WOU: Medicinal Chemistry

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Department of Chemistry

MEDICINAL CHEMISTRY AND PHARMACOLOGY

The Medicinal Chemistry and Pharmacology Emphasis Program is designed for students interested in applying for Pharmacy School, Medical School, Dental School, or continuing on to Graduate School in focus areas such as Medicinal Chemistry, Biochemistry, Cancer Research, Toxicology, and Pharmacology. Thus, the entry requirements for several medical schools, dental schools, pharmacy schools, and graduate programs, nation-wide, have served as the basis for the development of the program. This has resulted in a multi-disciplinary degree plan that incorporates key elements of the chemical, physical, and biological sciences. The primary focus of this program is to apply chemistry to the study of biologically and clinically active substances. Course study will focus on biological and pharmacological interactions of drugs and natural substances, rational drug design, the biochemistry of enzymes and receptors, molecular toxicology and the biological mechanisms of drug action, molecular graphics and rational drug design, quantitative structure-activity relationships, organic chemistry, molecular biology, and analytical chemistry techniques used in natural product isolation and drug development.

Students majoring in this emphasis area will receive a B.S. or B.A. degree in Chemistry with a minor in Medicinal Chemistry and Pharmcology – Natural Science Track. This degree plan provides a broad education in both the biological and chemical sciences, requiring 39 credits of biology coursework and 64 credits of chemistry coursework. The Natural Science Track minor option may be taken by majors in scientific disciplines other than Chemistry providing they complete the general chemistry series, CH221-223. The Medicinal Chemistry and Pharmacology Minor – Health and Community Track will provide a scientific foundation in biological chemistry for students majoring in the Health Sciences, Gerontology, Psychology, or other health-related fields. Emphasis-specific courses will also provide elective course offerings that will be of high interest and relevance to Nursing majors.

CHEMISTRY MAJOR – MEDICINAL CHEMISTRY AND PHARMACOLOGY OPTION (75 Credits):

Course Number    Course Title    Credit Hours    Frequency   
CH221,222,223    General Chemistry Series    15 (5-5-5)    twice annually (fall-winter-spring or winter-spring-fall)   
CH312    Quantitative Analysis    4    annually (winter term)   
CH313    Instrumental Analysis    4    annually (spring term)   
CH334,335, 336    Organic Chemistry Lecture Series    9 (3-3-3)    annually (fall-winter-spring)   
CH337 & CH338    Organic Chemistry Lab    3 (1-2)    annually (winter-spring)   
CH340    Elementary Physical Chemistry    4    alt years*(odd, spring term)   
CH350W    Chemical Literature    1    annually (winter term)   
CH407W    Chemistry Seminar    1    annually (spring term)   
CH450 & CH451    Biochemistry Series    6 (3-3)    annually (fall-winter terms)   
CH461-462 W    Experimental Chemistry    4 (2-2)    alt years (even fall-winter)*   
PH201,202,203 or PH211,212,213   

General Physics (Algebra-Based) or

General Physics (Calculus-Based)

12 (4-4-4)    annually (fall-winter-spring)   
BI334 & BI335    Advanced Human Anatomy and Physiology    8 (4-4)    annually (fall-winter)   
BI336    Human Histology and Physiology    4    annually (spring)   

*even and odd designations refer to the fall term calendar year (example: Fall 2013-Winter 2014-Spring 2014 is an odd calendar year)

Both the B.A. and B.S. degrees require the completion of MTH 251Calculus I, MTH252 Calculus II, and either CS 121 Computer Applications or 161 Computer Science I. The six hours of writing intensive course work should come from CH 350W, CH 407W, CH 461W and CH 462W. The sequence BI 211, 212, 213 Principles of Biology is to be completed as the LACC science requirement. Pre-professional students should take EC 201 Introduction to Microeconomics or EC202 Introduction to Macroeconomics as part of their LACC requirements. Students selecting this major must complete the Medicinal Chemistry and Pharmacology Minor (Natural Science Track) and maintain a C average in their major and minor coursework. The B.A. degreee also requires the completion of the third term of the second year of a modern language course.

MEDICINAL CHEMISTRY AND PHARMACOLOGY MINOR: Natural Science Track - 29 Credits

Course Number    Course Title    Credit Hours    Frequency   
CH322    Medicinal Chemistry and Pharmacology    3    alt years (odd winter terms)*   
CH345    Introduction to Toxicology    3    alt years (even fall term)*   
CH347    Biochemistry of Complementary and Alternative Medicines (CAM)    3    alt years (odd spring terms)*   
CH452    Biochemistry Lab    3    alt years (odd spring terms)*   
MTH243    Introduction to Probability and Statistics    4    quarterly   
BI314    Introductory Genetics    4    annually (fall term)   
BI315    Cell Biology    4    annually (winter term)   
BI331    General Microbiology    4    annually (spring term)   

*even and odd designations refer to the fall term calendar year (example: Fall 2013-Winter 2014-Spring 2014 is an odd calendar year)

This minor must be completed by students pursuing the Chemistry Major - Medicinal Chemistry and Pharmacology Option. This minor may also be taken by majors in scientific disciplines other than Chemistry providing they complete CH221-223. Biology majors selecting this minor option should select Math option C in their major course requirements and substitute CH334-338 and CH313 for BI314, BI315, BI331, and MTH243 in the minor option. Pre-professional Biology Majors should complete PH201-203 or PH211-213 as their LACC science requirements.

MEDICINAL CHEMISTRY AND PHARMACOLOGY MINOR: Health and Community Track – 26 credits

Course Number    Course Title    Credit Hours    Frequency   
CH104,105,106    Introductory Chemistry    12 (4-4-4)    twice annually (fall-winter-spring or winter-spring-fall), also typically offered during summer term.   
HE325    Nutrition    4    annually   
CH322    Medicinal Chemistry and Pharmacology    3    alt years (odd winter terms)*   
CH345    Introduction to Toxicology    3    alt years (even spring terms)*   
CH347    Biochemistry of Complementary and Alternative Medicines (CAM)    3    alt years (odd spring terms)*   

*even and odd designations refer to the fall term calendar year (example: Fall 2013-Winter 2014-Spring 2014 is an odd calendar year)

Potential Course Schedule for Chemistry Emphasis Majors Starting in Odd Years

YEAR 1 (odd) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
General Biology    BI211 - 5 credits    BI212 - 5 credits    BI213 - 5 credits   
General Chemistry    CH221 - 5 credits    CH222 - 5 credits    CH223 - 5 credits   
College Algebra    MTH111 - 4 credits       
Elementary Functions      MTH112 - 4 credits     
Calculus 1        MTH251 - 5 credits   
College Writing II    WR135 - 4 credits       
Principles of public speaking      COMM 111 - 3 credits     
Individual Health and Fitness        PE 131 - 2 credits   
Total Credits    18 credits    17 credits    17 credits   
YEAR 2 (even) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Organic Chemistry    CH334 - 3 credits    CH335 - 3 credits    CH336 - 3 credits   
Organic Lab I      CH337 - 1 credit     
Organic Lab II        CH338 - 2 credits   
Physics    PH201/PH211 - 4 credits    PH202/212 - 4 credits    PH203/213 - 4 credits   
Genetics    BI 314 - 4 credits       
Cell BIology      BI315 - 4 credits     
Microbiology        BI331 - 4 credits   
Calculus II    MTH 252 - 5 credits       
LACC Courses/MTH252    0-2    4 credits    4 credits   
Total Credits    16-18 credits    16 credits    17 credits   
YEAR 3 (odd) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Biochemistry    CH450 - 3 credits    CH451 - 3 credits     
Human Anatomy and Phys    BI334 - 4 credits    BI335 - 4 credits    BI336 - 4 credits   
Instrumental Analysis        CH313 - 4 credits   
Med Chem and Pharm      CH322 - 4 credits     
Biochemistry of CAM        CH347 - 3 credits   
Chem Lit      CH350 - 1 credit     
LACCs    8-10 credits    3-5 credits    4-6 credits   
Total Credits    15-17 credits    15-17 credits    15-17 credits   
YEAR 4 (even) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Experimental Chemistry    CH461 - 2 credits    CH462 - 2 credits     
Probability and Statistics    CH243 4 credits       
Quantitative Analysis      CH312 - 4 credits     
Intro to Toxicology    CH345 - 3 credits       
Elementary P-Chem        CH340 - 4 credits   
Chemistry Seminar        CH407 - 1 credit   
Biochemistry Lab        CH452 - 3 credits   
LACCs    6-8 credits    9-10 credits    7-8 credits   
Total Credits    15-17 credits    15-16 credits    15-16 credits   

Potential Course Schedule for Chemistry Emphasis Majors Starting in Even Years

YEAR 1 (even) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
General Biology    BI211 - 5 credits    BI212 - 5 credits    BI213 - 5 credits   
General Chemistry    CH221 - 5 credits    CH222 - 5 credits    CH223 - 5 credits   
College Algebra    MTH111 - 4 credits       
Elementary Functions      MTH112 - 4 credits     
Calculus 1        MTH251 - 5 credits   
College Writing II    WR135 - 4 credits       
Principles of public speaking      COMM 111 - 3 credits     
Individual Health and Fitness        PE 131 - 2 credits   
Total Credits    18 credits    17 credits    17 credits   
YEAR 2 (odd) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Organic Chemistry    CH334 - 3 credits    CH335 - 3 credits    CH336 - 3 credits   
Organic Chemistry Lab      CH337 - 1 credit    CH338 - 2 credits   
Physics    PH201/211 - 4 credits    PH202/212 - 4 credits    PH203/213 - 4 credits   
Genetics    BI314 - 4 credits       
Cell Biology      BI315 - 4 credits     
Chemical Literature      CH350 - 1 credit     

Instrumental Analysis

CH313 - 4 credits   
LACCs/MTH 252    4-6 credits    2-3 credits    2-3 credits   
Total Credits    15-17 credits    15-16 credits    15-16 credits   
YEAR 3 (even) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Biochemistry    CH450 - 3 credits    CH451 - 3 credits    CH452(Lab) - 3 credits    
Experimental Chemistry    CH461 - 2 credits    CH462 - 2 credits     
Quantitative Analysis      CH312 - 4 credits     
Elementary Physical Chem        CH340 - 4 credits   
Intro to Toxicology    CH345 - 3 credits       
LACCs    7-9 credits    6-8 credits    8-10 credits   
Total Credits    15-17 credits    15-17 credits    15-17 credits   
YEAR 4 (odd) courses     Fall - (CRN - Credits)    Winter (CRN - Credits)    Spring (CRN - Credits)   
Human Anatomy and Phys    BI334 - 4 credits    BI335 - 4 credits    BI336 - 4 credits   
Microbiology        BI331 - 4 credits   
Chemistry Seminar        CH407 - 1 credit   
Med Chem and Pharm      CH322 - 4 credits     
Biochemistry of CAM        CH347 - 3 credits   
LACCs    11-13 credits    7-9 credits    0-4 credits   
Total Credits    15-17 credits    15-17 credits    12-15 credits   

Contact

Department of Chemistry (503) 838-8207 | or e-mail: courtna@wou.edu

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