Warning: The NCBI web site requires JavaScript to function. more...

My NCBI   Sign in to NCBI   Sign Out

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

    Results: 1 to 20 of 110

    1.

    Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.

    Mercer N, Ramakrishnan B, Boeggeman E, Qasba PK.

    PLoS One. 2011;6(10):e26093. doi: 10.1371/journal.pone.0026093. Epub 2011 Oct 10.

    PMID:
    22016817
    [PubMed - indexed for MEDLINE]
    Free PMC Article

    Related citations

    2.

    alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.

    Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH.

    J Mol Biol. 2009 Dec 18;394(5):994-1010. doi: 10.1016/j.jmb.2009.09.026. Epub 2009 Sep 18.

    PMID:
    19766653
    [PubMed - indexed for MEDLINE]

    Related citations

    3.

    A novel method for preparation of HAMLET-like protein complexes.

    Permyakov SE, Knyazeva EL, Leonteva MV, Fadeev RS, Chekanov AV, Zhadan AP, Håkansson AP, Akatov VS, Permyakov EA.

    Biochimie. 2011 Sep;93(9):1495-501. doi: 10.1016/j.biochi.2011.05.002. Epub 2011 May 11.

    PMID:
    21596091
    [PubMed - indexed for MEDLINE]

    Related citations

    4.

    Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.

    Mossberg AK, Hun Mok K, Morozova-Roche LA, Svanborg C.

    FEBS J. 2010 Nov;277(22):4614-25. doi: 10.1111/j.1742-4658.2010.07890.x. Review.

    PMID:
    20977665
    [PubMed - indexed for MEDLINE]

    Related citations

    5.

    Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

    Svensson M, Fast J, Mossberg AK, Düringer C, Gustafsson L, Hallgren O, Brooks CL, Berliner L, Linse S, Svanborg C.

    Protein Sci. 2003 Dec;12(12):2794-804.

    PMID:
    14627739
    [PubMed - indexed for MEDLINE]
    Free PMC Article

    Related citations

    6.

    Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid.

    Knyazeva EL, Grishchenko VM, Fadeev RS, Akatov VS, Permyakov SE, Permyakov EA.

    Biochemistry. 2008 Dec 9;47(49):13127-37. doi: 10.1021/bi801423s.

    PMID:
    19006329
    [PubMed - indexed for MEDLINE]

    Related citations

    7.

    alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.

    Pettersson J, Mossberg AK, Svanborg C.

    Biochem Biophys Res Commun. 2006 Jun 23;345(1):260-70. Epub 2006 Apr 27.

    PMID:
    16678133
    [PubMed - indexed for MEDLINE]

    Related citations

    8.

    HAMLET binding to α-actinin facilitates tumor cell detachment.

    Trulsson M, Yu H, Gisselsson L, Chao Y, Urbano A, Aits S, Mossberg AK, Svanborg C.

    PLoS One. 2011 Mar 8;6(3):e17179. doi: 10.1371/journal.pone.0017179.

    PMID:
    21408150
    [PubMed - indexed for MEDLINE]
    Free PMC Article

    Related citations

    9.

    Heat-treatment method for producing fatty acid-bound alpha-lactalbumin that induces tumor cell death.

    Kamijima T, Ohmura A, Sato T, Akimoto K, Itabashi M, Mizuguchi M, Kamiya M, Kikukawa T, Aizawa T, Takahashi M, Kawano K, Demura M.

    Biochem Biophys Res Commun. 2008 Nov 7;376(1):211-4. doi: 10.1016/j.bbrc.2008.08.127. Epub 2008 Sep 5.

    PMID:
    18774773
    [PubMed - indexed for MEDLINE]

    Related citations

    10.

    Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

    Hallgren O, Aits S, Brest P, Gustafsson L, Mossberg AK, Wullt B, Svanborg C.

    Adv Exp Med Biol. 2008;606:217-40. doi: 10.1007/978-0-387-74087-4_8. Review.

    PMID:
    18183931
    [PubMed - indexed for MEDLINE]

    Related citations

    11.

    No need to be HAMLET or BAMLET to interact with histones: binding of monomeric alpha-lactalbumin to histones and basic poly-amino acids.

    Permyakov SE, Pershikova IV, Khokhlova TI, Uversky VN, Permyakov EA.

    Biochemistry. 2004 May 18;43(19):5575-82.

    PMID:
    15134431
    [PubMed - indexed for MEDLINE]

    Related citations

    12.

    Can misfolded proteins be beneficial? The HAMLET case.

    Pettersson-Kastberg J, Aits S, Gustafsson L, Mossberg A, Storm P, Trulsson M, Persson F, Mok KH, Svanborg C.

    Ann Med. 2009;41(3):162-76. doi: 10.1080/07853890802502614. Review.

    PMID:
    18985467
    [PubMed - indexed for MEDLINE]

    Related citations

    13.

    Molten globule of bovine alpha-lactalbumin at neutral pH induced by heat, trifluoroethanol, and oleic acid: a comparative analysis by circular dichroism spectroscopy and limited proteolysis.

    Polverino de Laureto P, Frare E, Gottardo R, Fontana A.

    Proteins. 2002 Nov 15;49(3):385-97.

    PMID:
    12360528
    [PubMed - indexed for MEDLINE]

    Related citations

    14.

    α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity.

    Spolaore B, Pinato O, Canton M, Zambonin M, Polverino de Laureto P, Fontana A.

    Biochemistry. 2010 Oct 5;49(39):8658-67. doi: 10.1021/bi1012832. Epub 2010 Sep 9.

    PMID:
    20804154
    [PubMed - indexed for MEDLINE]

    Related citations

    15.

    Compact oleic acid in HAMLET.

    Fast J, Mossberg AK, Nilsson H, Svanborg C, Akke M, Linse S.

    FEBS Lett. 2005 Nov 7;579(27):6095-100. Epub 2005 Oct 6.

    PMID:
    16229842
    [PubMed - indexed for MEDLINE]

    Related citations

    16.

    Changes in proteasome structure and function caused by HAMLET in tumor cells.

    Gustafsson L, Aits S, Onnerfjord P, Trulsson M, Storm P, Svanborg C.

    PLoS One. 2009;4(4):e5229. doi: 10.1371/journal.pone.0005229. Epub 2009 Apr 14.

    PMID:
    19365565
    [PubMed - indexed for MEDLINE]
    Free PMC Article

    Related citations

    17.

    HAMLET interacts with lipid membranes and perturbs their structure and integrity.

    Mossberg AK, Puchades M, Halskau Ø, Baumann A, Lanekoff I, Chao Y, Martinez A, Svanborg C, Karlsson R.

    PLoS One. 2010 Feb 23;5(2):e9384. doi: 10.1371/journal.pone.0009384.

    PMID:
    20186341
    [PubMed - indexed for MEDLINE]
    Free PMC Article

    Related citations

    18.

    Oleic acid is a key cytotoxic component of HAMLET-like complexes.

    Permyakov SE, Knyazeva EL, Khasanova LM, Fadeev RS, Zhadan AP, Roche-Hakansson H, Håkansson AP, Akatov VS, Permyakov EA.

    Biol Chem. 2012 Jan 1;393(1-2):85-92. doi: 10.1515/BC-2011-230.

    PMID:
    22628302
    [PubMed - indexed for MEDLINE]

    Related citations

    19.

    Stepwise proteolytic removal of the beta subdomain in alpha-lactalbumin. The protein remains folded and can form the molten globule in acid solution.

    Polverino de Laureto P, Vinante D, Scaramella E, Frare E, Fontana A.

    Eur J Biochem. 2001 Aug;268(15):4324-33.

    PMID:
    11488928
    [PubMed - indexed for MEDLINE]
    Free Article

    Related citations

    20.

    The oleic acid complexes of proteolytic fragments of alpha-lactalbumin display apoptotic activity.

    Tolin S, De Franceschi G, Spolaore B, Frare E, Canton M, Polverino de Laureto P, Fontana A.

    FEBS J. 2010 Jan;277(1):163-73. doi: 10.1111/j.1742-4658.2009.07466.x. Epub 2009 Nov 26.

    PMID:
    19968717
    [PubMed - indexed for MEDLINE]

    Related citations

      Format
      Items per page
      Sort by

      Send to:

      Choose Destination

      Supplemental Content

      Filters: Manage Filters

      Find related data

      Recent activity

      Clear   Turn Off   Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      You are here: NCBI > Literature > PubMed
      Write to the Help Desk
      Text Only Options

      Top of page

      Text Only Options

      Open the original version of this page.

      Usablenet Assistive is a UsableNet product. Usablenet Assistive Main Page.