The Genome Reference Consortium
Putting sequences into a chromosome context.
The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome. Subsequent analysis has shown that for most mammalian genomes a single tiling path is insufficient to represent a genome in regions with complex allelic diversity. The GRC is now working to create assemblies that better represent this diversity and provide more robust substrates for genome analysis.
Subscribe to the grc-announce email list to receive email notification for all GRC assembly updates.
An issue has been encountered in the processing of the GRCh38 assembly. This issue is expected to delay the release of the assembly by several weeks. We will provide an updated release date estimate as it becomes available. If you have questions or concerns about this let us know.
Slides from the GRC's presentation at ASHG 2013 are available on the Workshops page.
We are planning to update the zebrafish reference assembly to GRCz10 in early 2014. If you have questions or concerns about this let us know.