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The Genome Reference Consortium

Putting sequences into a chromosome context.

The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome. Subsequent analysis has shown that for most mammalian genomes a single tiling path is insufficient to represent a genome in regions with complex allelic diversity. The GRC is now working to create assemblies that better represent this diversity and provide more robust substrates for genome analysis.

The GRC are now providing a track hub that will allow you to view tracks associated with our curator efforts in a range of genome browsers, including Ensembl and UCSC. The location of this hub is: http://ngs.sanger.ac.uk/production/grit/track_hub/hub.txt

Slides from presentations at the 2014 GRC Assembly Workshop at Genome Informatics are now available: http://www.slideshare.net/GenomeRef.

Transitioning to GRCh38 or GRCz10? Try the NCBI Remapping Service, which uses the same assembly-assembly alignments used by the GRC.

Subscribe to the grc-announce email list to receive email notification for all GRC assembly updates.

Page last updated: January 2, 2014

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