(Sty) Salmonella typhimurium LT2
generin.cgi	Functional categories
	Fun	All	J	A	K	L	B	D	Y	V	T	M	N	Z	W	U	O	C	G	E	F	H	I	P	Q	R	S
	COGs	2,167	141	2	93	114	-	30	-	26	64	135	57	-	1	66	96	164	158	199	71	136	54	127	37	264	297
	proteins	3,863	185	2	361	196	-	37	-	48	200	260	127	-	1	143	167	315	431	446	88	174	99	270	81	555	372
	Distribution of COGs by number of proteins
	proteins	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	21	23	30	51	68
	COGs	1499	337	162	72	24	20	9	9	8	2	3	8	1	6	2	1	1	1	1	1

Co-ocurrences in sister taxa	0	1	2	3	4	5
order Enterobacteriales	101	45	38	288	1142	553

+    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    ++    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 68    [G    E    P    R]    COG0477 Permeases of the major facilitator superfamily
||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 51    [K]    COG0583 Transcriptional regulator
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 30    [K]    COG2207 AraC-type DNA-binding domain-containing proteins
------------------------------------------|||||--|--|------------- 23    [N    U]    COG3539 P pilus assembly protein, pilin FimA
|-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 21    [T]    COG0642 Signal transduction histidine kinase
----------------||--||----|---||||||||----|||||-||||-|||---||||--- 15    [K    G]    COG1349 Transcriptional regulators of sugar metabolism
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||-- 15    [K]    COG1609 Transcriptional regulators
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||-- 14    [C]    COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 14    [K    R]    COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
|||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 14    [L]    COG0582 Integrase
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 14    [T    K]    COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 14    [T]    COG2200 FOG: EAL domain
------------------|--|--------------------|||||--|--|--|---||-|--| 14    [N    U]    COG3121 P pilus assembly protein, chaperone PapD
---------||-------||-|----||||||--||||----|||||-||-----|---|||||-- 13    [K]    COG2771 DNA-binding HTH domain-containing proteins
|-||||--|-|||||||||||||||-||||||||||||----|||||||||||||||||||||||| 12    [L    R]    COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
|||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 12    [Q    R]    COG0500 SAM-dependent methyltransferases
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||-- 12    [G]    COG0524 Sugar kinases, ribokinase family
|-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 12    [G    E    R]    COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 12    [C]    COG1012 NAD-dependent aldehyde dehydrogenases
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 12    [K]    COG1309 Transcriptional regulator
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 12    [T]    COG2199 FOG: GGDEF domain
------------------|-----------------------|||||--|--|--|---|--|--| 12    [N    U]    COG3188 P pilus assembly protein, porin PapC
--||---||-|||---|-------------------------|||||-||||---|--|-|-|--- 11    [C]    COG0437 Fe-S-cluster-containing hydrogenase components 1
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---||||||| 11    [E]    COG0531 Amino acid transporters
--|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 11    [I    Q    R]    COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 10    [T    K]    COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 10    [L]    COG2801 Transposase and inactivated derivatives
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  9    [M]    COG0463 Glycosyltransferases involved in cell wall biogenesis
-------------||---||------------||--------|||||-||||||||---|||||||  9    [O]    COG0625 Glutathione S-transferase
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-|||||||||||||  9    [E    T]    COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  9    [N    T]    COG0840 Methyl-accepting chemotaxis protein
----------------||||||--|||---|-||||||----|||||-||||||||||||||||||  9    [M]    COG0845 Membrane-fusion protein
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---|||||||  9    [K]    COG1396 Predicted transcriptional regulators
---------------------|----|||||----|||----|||||-||||-|||---|||||--  9    [K]    COG2186 Transcriptional regulators
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  9    [M    R]    COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
||||||||||||||||||||||---|||||||||||||----|||||-||||||||||||||||||  8    [M]    COG0438 Glycosyltransferase
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  8    [M    G]    COG0451 Nucleoside-diphosphate-sugar epimerases
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  8    [O    C]    COG0526 Thiol-disulfide isomerase and thioredoxins
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|---  8    [R]    COG0561 Predicted hydrolases of the HAD superfamily
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||--  8    [R]    COG0673 Predicted dehydrogenases and related proteins
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||--  8    [T]    COG0784 FOG: CheY-like receiver
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  8    [K]    COG0789 Predicted transcriptional regulators
------------------------------------------|||||||-||-|||----------  8    [M]    COG3203 Outer membrane protein (porin)
------------------------------------------|||||---||-||----|||||||  8    [M]    COG3637 Opacity protein and related surface antigens
----------------||||----||----||||-|||----||||||||||||||||||||||||  7    [M]    COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  7    [M]    COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
-------------|||------||--|---------------|||||-||||-||-|||-------  7    [E]    COG0814 Amino acid permeases
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  7    [E    R]    COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
--------------------------|||||||-||||----|||||--|---------|-|----  7    [E]    COG1113 Gamma-aminobutyrate permease and related permeases
---|------------||---|----|||-------||----|||||-||||---|--||||||--  7    [K]    COG1414 Transcriptional regulator
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||--  7    [G    T]    COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  7    [L]    COG1943 Transposase and inactivated derivatives
------------------|||---------||----|-----|||||----------------|--  7    [G]    COG2211 Na+/melibiose symporter and related transporters
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  6    [G]    COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  6    [R]    COG0457 FOG: TPR repeat
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  6    [P]    COG0471 Di- and tricarboxylate transporters
--||||--|-|||||||-||||---|||||||-||||||||||||||-||||||||||||||||||  6    [R]    COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  6    [M]    COG0668 Small-conductance mechanosensitive channel
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  6    [E]    COG0765 ABC-type amino acid transport system, permease component
-------------|||-----|--------------------|||||-||||-|||||||||||--  6    [R]    COG0790 FOG: TPR repeat, SEL1 subfamily
--|-------------||||||---|----|---|-||----|||||-||||||||||||||||||  6    [V]    COG0841 Cation/multidrug efflux pump
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  6    [G]    COG1070 Sugar (pentulose and hexulose) kinases
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  6    [C]    COG1145 Ferredoxin
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  6    [K]    COG1278 Cold shock proteins
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||--  6    [K]    COG1802 Transcriptional regulators
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||--  6    [K]    COG1846 Transcriptional regulators
--------------------|||||||---||||||||||||||||||||||||||---|||||--  6    [G]    COG1925 Phosphotransferase system, HPr-related proteins
---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||--  6    [K    G]    COG1940 Transcriptional regulator/sugar kinase
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  6    [K]    COG2188 Transcriptional regulators
--|-----------------|-----|---|-|-|-||----|||||-||||-|||----------  6    [G    E]    COG2610 H+/gluconate symporter and related permeases
--------------------------|---|-||||-|-||-|||-|-|--|--------------  6    [G]    COG3414 Phosphotransferase system, galactitol-specific IIB component
---------------------------||--------|----|||||-|-----------|-|---  6    [K]    COG3710 DNA-binding winged-HTH domains
------------------|||--------------|------|||-|-------------------  6    [Q    C]    COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  5    [I    Q]    COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  5    [L    K    J]    COG0513 Superfamily II DNA and RNA helicases
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  5    [S]    COG0586 Uncharacterized membrane-associated protein
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  5    [T]    COG0589 Universal stress protein UspA and related nucleotide-binding proteins
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  5    [P]    COG0607 Rhodanese-related sulfurtransferase
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  5    [R]    COG0637 Predicted phosphatase/phosphohexomutase
|||-----|--|-----|||----------|-----------|||||---||--------|-----  5    [R]    COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  5    [H    C]    COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  5    [I]    COG0671 Membrane-associated phospholipid phosphatase
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  5    [V]    COG0842 ABC-type multidrug transport system, permease component
-----------------|||----------|----||-----|||||-||-----|----------  5    [K    T]    COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  5    [P]    COG1226 Kef-type K+ transport systems, predicted NAD-binding component
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  5    [E]    COG1280 Putative threonine efflux protein
------------------|--|------------|||-----|||||-||||||||--|||||---  5    [S]    COG1289 Predicted membrane protein
--------------------||---||---||||||||-||||||||-||||---|----------  5    [G]    COG1445 Phosphotransferase system fructose-specific component IIB
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  5    [C]    COG1454 Alcohol dehydrogenase, class IV
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  5    [I]    COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
----------------|-|||---------------------|||||-||||||||||||||||||  5    [M    U]    COG1538 Outer membrane protein
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||--  5    [I]    COG1960 Acyl-CoA dehydrogenases
------------------|||------||||--|||||----|||||-||||---|----|-----  5    [E]    COG1982 Arginine/lysine/ornithine decarboxylases
----------------------||-------||-|-|-----|||||-||||------|-----||  5    [G]    COG2271 Sugar phosphate permease
--------------------|---------||||-||-----|||||----|||||---|||||--  5    [G]    COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
----------------|-------------------------|||||---||----------|---  5    [R]    COG3302 DMSO reductase anchor subunit
---|-------|------------------------------|||||-|-||---|----------  5    [R]    COG3381 Uncharacterized component of anaerobic dehydrogenases
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  4    [E    H]    COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  4    [Q]    COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  4    [G]    COG0246 Mannitol-1-phosphate/altronate dehydrogenases
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  4    [S]    COG0316 Uncharacterized conserved protein
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  4    [G]    COG0366 Glycosidases
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  4    [R]    COG0388 Predicted amidohydrolase
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4    [O]    COG0443 Molecular chaperone
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  4    [R]    COG0488 ATPase components of ABC transporters with duplicated ATPase domains
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  4    [J]    COG0564 Pseudouridylate synthases, 23S RNA-specific
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  4    [E    P]    COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  4    [R]    COG0628 Predicted permease
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  4    [R]    COG0656 Aldo/keto reductases, related to diketogulonate reductase
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||--  4    [E]    COG0665 Glycine/D-amino acid oxidases (deaminating)
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  4    [R]    COG0670 Integral membrane protein, interacts with FtsH
|||---||||-|----|-||----------|-----------|||-|---------|||-------  4    [C]    COG0680 Ni,Fe-hydrogenase maturation factor
|||-----||---||---|||---|-----||||-||-----|||||||||||--||||-------  4    [C]    COG0716 Flavodoxins
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  4    [G]    COG0726 Predicted xylanase/chitin deacetylase
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  4    [F]    COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
----------------||||||||||||||||||||||----||||||||||||||||||||||||  4    [M]    COG0768 Cell division protein FtsI/penicillin-binding protein 2
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  4    [L]    COG0776 Bacterial nucleoid DNA-binding protein
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  4    [O]    COG0826 Collagenase and related proteases
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  4    [L]    COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
------------------||-|----|||-|---||||----||||||||||||||||||||||||  4    [P]    COG0861 Membrane protein TerC, possibly involved in tellurium resistance
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  4    [R]    COG1011 Predicted hydrolase (HAD superfamily)
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4    [E]    COG1126 ABC-type polar amino acid transport system, ATPase component
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  4    [V]    COG1132 ABC-type multidrug transport system, ATPase and permease components
|||---||||-------|||----------------------|||||-------------------  4    [C]    COG1142 Fe-S-cluster-containing hydrogenase components 2
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||---  4    [E    P]    COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  4    [E]    COG1174 ABC-type proline/glycine betaine transport systems, permease component
|||-|||||||||---||--|------||-||||||------|||||-||||---|----------  4    [O]    COG1180 Pyruvate-formate lyase-activating enzyme
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  4    [J]    COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  4    [C]    COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
--------------------|----||---||||||||-|||||||||||-|---|-------|--  4    [G]    COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
--------------------|----||---||||||||||||||||||||-|---|-------|--  4    [G]    COG1264 Phosphotransferase system IIB components
--------------------||---||---||||||||-||||||||-|||----|----------  4    [G]    COG1299 Phosphotransferase system, fructose-specific IIC component
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  4    [Q]    COG1335 Amidases related to nicotinamidase
-----------------|||------|||||-----||----|||-|-||---|||---||||---  4    [S]    COG1376 Uncharacterized protein conserved in bacteria
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||--  4    [K]    COG1522 Transcriptional regulators
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  4    [O]    COG1651 Protein-disulfide isomerase
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  4    [M]    COG1686 D-alanyl-D-alanine carboxypeptidase
----------------|-----||||----|-----||----||||||||||||||--||||||||  4    [T]    COG1734 DnaK suppressor protein
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  4    [K]    COG1737 Transcriptional regulators
--------------------||----||||||||||||----|||||-||||-|||||||||||--  4    [E]    COG1760 L-serine deaminase
|||---||||-||-------|-----------|---------|||-|-|||---------------  4    [H]    COG1767 Triphosphoribosyl-dephospho-CoA synthetase
|||---|||||-----||------------|------|----|||||-||--||||-----||---  4    [C]    COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  4    [G]    COG1879 ABC-type sugar transport system, periplasmic component
|-------|-----------|---------||||||------|||||-|-||---|----------  4    [C]    COG1882 Pyruvate-formate lyase
------------------|-------|||-||||||||----|||||-||||-||-----------  4    [G]    COG1929 Glycerate kinase
|||---|||||-----||------------|------|----|||||-||--||||-----||---  4    [C]    COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  4    [L]    COG1961 Site-specific recombinases, DNA invertase Pin homologs
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  4    [K    T]    COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  4    [P]    COG2076 Membrane transporters of cations and cationic drugs
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  4    [I]    COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
------------------------------------------|||||-|||||||-||||||--||  4    [R]    COG2194 Predicted membrane-associated, metal-dependent hydrolase
-------------||---||----------------------|||||-||||----------|---  4    [T]    COG2198 FOG: HPt domain
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  4    [T]    COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  4    [F]    COG2233 Xanthine/uracil permeases
---|-------||-------||----|||--||---------|||||-|||----|---|||||--  4    [G]    COG2301 Citrate lyase beta subunit
--------------------|---------|--|-----|--|||||-|-||----||--------  4    [G]    COG2731 Beta-galactosidase, beta subunit
--------------------------|||--|--||||----|||||--||||--||||||-|---  4    [G]    COG2814 Arabinose efflux permease
-------------|||----------|---||--|||-----|||||-|---|||--------|--  4    [E]    COG3104 Dipeptide/tripeptide permease
--||---|------|------------||-------------|||||--|||-------|||||--  4    [P]    COG3119 Arylsulfatase A and related enzymes
------------------------------------------|||||-||-----|---|--|---  4    [S]    COG3157 Hemolysin-coregulated protein (uncharacterized)
--------------------|---------||||-||-----|||||----|--------------  4    [G]    COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB
------------------||----------------------|||||-||----||----|-----  4    [U    N    T    P]    COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
--------------------|---------||||-||-----|||||----|--------------  4    [G]    COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC
--------------------|---------||||-||-----|||||----|--------------  4    [G]    COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID
-------------------|----------|-----------|||||-----|--|------||-|  4    [R]    COG3772 Phage-related lysozyme (muraminidase)
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  4    [E]    COG4166 ABC-type oligopeptide transport system, periplasmic component
---------------------|-------------|||----|||||-|-----------------  4    [R]    COG4533 ABC-type uncharacterized transport system, periplasmic component
---------------------|--------||-|||||--|-||||||||||---|----------  4    [G]    COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
------------------||----------------------|||||------------------|  4    [S]    COG5464 Uncharacterized conserved protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3    [J]    COG0008 Glutamyl- and glutaminyl-tRNA synthetases
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  3    [E]    COG0031 Cysteine synthase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  3    [G]    COG0036 Pentose-5-phosphate-3-epimerase
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  3    [P]    COG0038 Chloride channel protein EriC
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  3    [J]    COG0042 tRNA-dihydrouridine synthase
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  3    [O]    COG0071 Molecular chaperone (small heat shock protein)
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3    [L]    COG0084 Mg-dependent DNase
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  3    [H    E]    COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  3    [E    G]    COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  3    [E]    COG0169 Shikimate 5-dehydrogenase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  3    [G]    COG0176 Transaldolase
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  3    [I]    COG0183 Acetyl-CoA acetyltransferase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  3    [G]    COG0191 Fructose/tagatose bisphosphate aldolase
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  3    [I]    COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  3    [L]    COG0210 Superfamily I DNA and RNA helicases
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  3    [J]    COG0251 Putative translation initiation inhibitor, yjgF family
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  3    [E    J]    COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  3    [O]    COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
|||---|||||||-----------------|-|||-|--||-|||-|-|-||--------------  3    [G]    COG0269 3-hexulose-6-phosphate synthase and related proteins
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  3    [C]    COG0280 Phosphotransacetylase
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  3    [C]    COG0282 Acetate kinase
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  3    [E    M]    COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  3    [O]    COG0330 Membrane protease subunits, stomatin/prohibitin homologs
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||--  3    [E]    COG0346 Lactoylglutathione lyase and related lyases
|||||||||||||-|--|||----------||||-|||----|||||-------------|-----  3    [C]    COG0371 Glycerol dehydrogenase and related enzymes
--|-----||------|--|----------|-----------|||-|---------|||-------  3    [C]    COG0374 Ni,Fe-hydrogenase I large subunit
|||---||||------|-||-|--------------------|||-|---------|||-------  3    [R]    COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  3    [L]    COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  3    [M]    COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  3    [E]    COG0436 Aspartate/tyrosine/aromatic aminotransferase
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  3    [M]    COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  3    [R]    COG0491 Zn-dependent hydrolases, including glyoxylases
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  3    [E    R]    COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  3    [O]    COG0501 Zn-dependent protease with chaperone function
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  3    [I]    COG0511 Biotin carboxyl carrier protein
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  3    [F]    COG0516 IMP dehydrogenase/GMP reductase
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  3    [R]    COG0517 FOG: CBS domain
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  3    [E]    COG0527 Aspartokinases
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  3    [V]    COG0534 Na+-driven multidrug efflux pump
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  3    [O]    COG0542 ATPases with chaperone activity, ATP-binding subunit
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  3    [H    C]    COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
|||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||--  3    [E]    COG0560 Phosphoserine phosphatase
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  3    [J]    COG0566 rRNA methylases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  3    [K]    COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  3    [P]    COG0609 ABC-type Fe3+-siderophore transport system, permease component
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  3    [P]    COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  3    [O    U]    COG0616 Periplasmic serine proteases (ClpP class)
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  3    [E]    COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  3    [E]    COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
---|---------||||-||-|||--|---------------||||||||||-|||---|||||||  3    [C]    COG0633 Ferredoxin
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  3    [H]    COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  3    [T]    COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
|||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||--  3    [C]    COG0644 Dehydrogenases (flavoproteins)
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  3    [C]    COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  3    [R]    COG0693 Putative intracellular protease/amidase
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  3    [O]    COG0695 Glutaredoxin and related proteins
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  3    [M    G]    COG0702 Predicted nucleoside-diphosphate-sugar epimerases
-------------||----|-|----|----|-|--------||||||||||||||------||--  3    [E]    COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
----------------||||||--||||||||--||||----||||||||||||||||||||||||  3    [M]    COG0739 Membrane proteins related to metalloendopeptidases
----------------||||||||||||||||||||||----||||||||||||||||||||||||  3    [O    U]    COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||----||||||||||||----||||||||||||||||||||||--  3    [M]    COG0744 Membrane carboxypeptidase (penicillin-binding protein)
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  3    [E]    COG0747 ABC-type dipeptide transport system, periplasmic component
------------------|-----------------------|||||---|-----||||---|--  3    [E]    COG0754 Glutathionylspermidine synthase
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  3    [O]    COG0760 Parvulin-like peptidyl-prolyl isomerase
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  3    [C]    COG0778 Nitroreductase
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  3    [K]    COG0782 Transcription elongation factor
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  3    [M]    COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-|||---------------------|||||-|||||||||||---||--  3    [M]    COG0859 ADP-heptose:LPS heptosyltransferase
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  3    [M]    COG0860 N-acetylmuramoyl-L-alanine amidase
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  3    [C]    COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---|||||||  3    [I]    COG1024 Enoyl-CoA hydratase/carnithine racemase
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  3    [C]    COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  3    [R]    COG1073 Hydrolases of the alpha/beta superfamily
-------------|||--|-----------------------||||||||||-|||--||||||||  3    [O]    COG1076 DnaJ-domain-containing proteins 1
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  3    [G]    COG1082 Sugar phosphate isomerases/epimerases
-----------------|--||---||||-||||||||--|||||||-||||---|----------  3    [G]    COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  3    [P]    COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  3    [G]    COG1109 Phosphomannomutase
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  3    [P    H]    COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  3    [G]    COG1129 ABC-type sugar transport system, ATPase component
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  3    [V]    COG1131 ABC-type multidrug transport system, ATPase component
--|-----|-|-|--------|--------------------|||||-|||||------|||||||  3    [O]    COG1138 Cytochrome c biogenesis factor
----------------||----||||----|----|||----||||||||-----|||||||||--  3    [N    U]    COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  3    [K    E]    COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  3    [E]    COG1171 Threonine dehydratase
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  3    [G]    COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  3    [E]    COG1177 ABC-type spermidine/putrescine transport system, permease component II
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  3    [J]    COG1186 Protein chain release factor B
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  3    [R]    COG1253 Hemolysins and related proteins containing CBS domains
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  3    [C]    COG1271 Cytochrome bd-type quinol oxidase, subunit 1
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  3    [C]    COG1294 Cytochrome bd-type quinol oxidase, subunit 2
|-|||||||||||||||-||-|-----||--------------||||--|-----|----------  3    [R]    COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily
----------------||------||----|----|||----|||||-||-----|||||||||--  3    [N]    COG1344 Flagellin and related hook-associated proteins
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  3    [S]    COG1357 Uncharacterized low-complexity proteins
----------------||||-|----|---||--||------|||||-||||||||---|||||||  3    [S]    COG1434 Uncharacterized conserved protein
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  3    [K]    COG1475 Predicted transcriptional regulators
--|-------------|----------||-|||||||||---||||||-------|---||-|---  3    [L]    COG1484 DNA replication protein
---------------------|||------------||----|||||-||||||||||||||||||  3    [O]    COG1495 Disulfide bond formation protein DsbB
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  3    [G]    COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
--------------------|-||--||||------------|||||-||||||||||||||||||  3    [M]    COG1560 Lauroyl/myristoyl acyltransferase
----------------|-----------------|-|-----|||||-|||--|||---|||||||  3    [V]    COG1566 Multidrug resistance efflux pump
-----------------|--|---|-|----------|----|--||-||||-------||--|--  3    [G]    COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  3    [E]    COG1605 Chorismate mutase
----------------|-|||---------------------|||||-||||||||||||||||--  3    [P]    COG1629 Outer membrane receptor proteins, mostly Fe transport
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  3    [G]    COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  3    [J]    COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
--|-----|-------|--|----------|-----------|||-|---------|||-------  3    [C]    COG1740 Ni,Fe-hydrogenase I small subunit
--|-||----|-------||------|||-|-----------|||||-||-|---|---|||||--  3    [R]    COG1741 Pirin-related protein
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  3    [U]    COG1826 Sec-independent protein secretion pathway components
------|||--------|--|---|-------|-------------|-|--|--------------  3    [C]    COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  3    [N    U]    COG1886 Flagellar motor switch/type III secretory pathway protein
||--|----|------|-------------------------|||||--|||----|||||-|---  3    [E]    COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  3    [C]    COG2025 Electron transfer flavoprotein, alpha subunit
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  3    [P]    COG2032 Cu/Zn superoxide dismutase
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  3    [Q]    COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  3    [C]    COG2055 Malate/L-lactate dehydrogenases
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  3    [C]    COG2086 Electron transfer flavoprotein, beta subunit
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  3    [U]    COG2095 Multiple antibiotic transporter
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  3    [R]    COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
---------|---|------|---------|||||||-----|||||-||||--------------  3    [P]    COG2116 Formate/nitrite family of transporters
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||--  3    [T]    COG2202 FOG: PAS/PAC domain
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  3    [P]    COG2217 Cation transport ATPase
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  3    [M]    COG2222 Predicted phosphosugar isomerases
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  3    [R]    COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  3    [R]    COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  3    [J]    COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  3    [S]    COG2606 Uncharacterized conserved protein
------------------------------|-----------|||||-|-||----|||-------  3    [R]    COG2704 Anaerobic C4-dicarboxylate transporter
----|------|------------------|-----||----|||||--------|--||||||--  3    [G]    COG2721 Altronate dehydratase
----------------|--||-||||-||-------------||||||||||||||||||||||||  3    [M]    COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
-------------------|----------------------|||-|-|---||||---||----|  3    [K]    COG2944 Predicted transcriptional regulator
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||--  3    [L]    COG2963 Transposase and inactivated derivatives
--------------------------|-----||||-|-||-|||||-|--|--------------  3    [S]    COG3037 Uncharacterized protein conserved in bacteria
------------------|-----------------------|||||-||-||-||---|||||-|  3    [C]    COG3038 Cytochrome B561
---------------------|--------------------|||||--||||------|||||--  3    [O]    COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes
--------------------|-----|----------|----|--||-||||-------||--|--  3    [G]    COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
------------------------------------------|||||-||||--------------  3    [S]    COG3111 Uncharacterized conserved protein
------------------|-----------------------|||-|--|----------------  3    [S]    COG3204 Uncharacterized protein conserved in bacteria
--------------------------|-----|---||----|||-|-|-----------------  3    [T]    COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism
------------------------------------------|||||---||--|-----------  3    [K]    COG3423 Predicted transcriptional regulator
------------------------------------------|||||---||-||----||||---  3    [M    U]    COG3468 Type V secretory pathway, adhesin AidA
------|||---------------|---------------------|-|--|--------------  3    [C]    COG3630 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit
-------------------|----------------|-----|||-|--|-------------|--  3    [R]    COG3729 General stress protein
------------------------------------------|||||--|||--------------  3    [M]    COG3765 Chain length determinant protein
------------------------------|-||||-|----|||-|-------------------  3    [G]    COG3775 Phosphotransferase system, galactitol-specific IIC component
---------------------|------------|-------|||||--|-|---|---||||---  3    [G]    COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  3    [E]    COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
------------------------------|----||---------|-------------------  3    [K]    COG3933 Transcriptional antiterminator
------------------------------------------|||||--||||------|||||--  3    [O]    COG4235 Cytochrome c biogenesis factor
---------------------------||--------------||-|-|-|-|--|----|-----  3    [S]    COG4453 Uncharacterized protein conserved in bacteria
--------------------------|-----|---||----|||-|-|-----------------  3    [K    T]    COG4565 Response regulator of citrate/malate metabolism
------------------------------------------|||||--|-|---|----------  3    [S]    COG4575 Uncharacterized conserved protein
-------------------------------------------||||--|-----|----------  3    [S]    COG4672 Phage-related protein
-------------------------------------------||||--|-----|----------  3    [S]    COG4718 Phage-related protein
-------------------------------------------||||--|-----|----------  3    [S]    COG4723 Phage-related protein, tail component
-------------------------------------------||||--|-----|----------  3    [S]    COG4733 Phage-related protein, tail component
------------------------------------------|||||-||--------||------  3    [P]    COG4771 Outer membrane receptor for ferrienterochelin and colicins
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  3    [E]    COG4992 Ornithine/acetylornithine aminotransferase
-------------------------------------------||||--|-----|---|-|----  3    [S]    COG5281 Phage-related minor tail protein
------------------------------|----||------||||-------------------  3    [N]    COG5492 Bacterial surface proteins containing Ig-like domains
-------------------------------------------||-|-----|--|----------  3    [R]    COG5511 Bacteriophage capsid protein
-------------------|---------------|------|||-|-----|--|----------  3    [R]    COG5525 Bacteriophage tail assembly protein
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  2    [E]    COG0006 Xaa-Pro aminopeptidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  2    [J]    COG0009 Putative translation factor (SUA5)
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  2    [E]    COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  2    [E]    COG0019 Diaminopimelate decarboxylase
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  2    [G]    COG0021 Transketolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [D]    COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  2    [H]    COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0050 GTPases - translation elongation factors
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  2    [G]    COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  2    [G]    COG0058 Glucan phosphorylase
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  2    [E]    COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  2    [E]    COG0066 3-isopropylmalate dehydratase small subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [R]    COG0073 EMAP domain
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  2    [C]    COG0074 Succinyl-CoA synthetase, alpha subunit
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  2    [E]    COG0078 Ornithine carbamoyltransferase
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  2    [E]    COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  2    [R]    COG0110 Acetyltransferase (isoleucine patch superfamily)
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  2    [E    H]    COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  2    [H]    COG0132 Dethiobiotin synthetase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  2    [E]    COG0136 Aspartate-semialdehyde dehydrogenase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2    [H]    COG0142 Geranylgeranyl pyrophosphate synthase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  2    [J]    COG0144 tRNA and rRNA cytosine-C5-methylases
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [E    H]    COG0147 Anthranilate/para-aminobenzoate synthases component I
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  2    [H]    COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  2    [H]    COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [F]    COG0167 Dihydroorotate dehydrogenase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  2    [E    H]    COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0180 Tryptophanyl-tRNA synthetase
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  2    [H    J]    COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  2    [F]    COG0208 Ribonucleotide reductase, beta subunit
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  2    [F]    COG0209 Ribonucleotide reductase, alpha subunit
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  2    [S]    COG0217 Uncharacterized conserved protein
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0223 Methionyl-tRNA formyltransferase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  2    [P]    COG0226 ABC-type phosphate transport system, periplasmic component
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [I    Q]    COG0236 Acyl carrier protein
-|--||-------|||--|-|------||-|-----------|||||||||||||||||---||--  2    [E]    COG0241 Histidinol phosphatase and related phosphatases
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  2    [C]    COG0247 Fe-S oxidoreductase
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  2    [F    P]    COG0248 Exopolyphosphatase
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [K]    COG0250 Transcription antiterminator
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0254 Ribosomal protein L31
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  2    [J]    COG0257 Ribosomal protein L36
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  2    [E]    COG0260 Leucyl aminopeptidase
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  2    [L]    COG0266 Formamidopyrimidine-DNA glycosylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  2    [C]    COG0277 FAD/FMN-containing dehydrogenases
-|--||----------|-|-|------||-|-----------||||||||||-||-|||---|---  2    [G]    COG0279 Phosphoheptose isomerase
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  2    [C]    COG0281 Malic enzyme
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  2    [P]    COG0288 Carbonic anhydrase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  2    [G]    COG0296 1,4-alpha-glucan branching enzyme
|||---||||--------||----------|-----------|||-|---|-----|||-------  2    [O]    COG0298 Hydrogenase maturation factor
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  2    [I    Q]    COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  2    [R]    COG0312 Predicted Zn-dependent proteases and their inactivated homologs
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  2    [T    K]    COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  2    [L]    COG0322 Nuclease subunit of the excinuclease complex
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  2    [E]    COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-|--|||-----------|||---|-----|----|-|----|||||-|-||||--||-------|  2    [L]    COG0338 Site-specific DNA methylase
-------------||---||-|----|---------------|||||-||||||||---|||||--  2    [E]    COG0339 Zn-dependent oligopeptidases
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  2    [E]    COG0347 Nitrogen regulatory protein PII
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  2    [L]    COG0350 Methylated DNA-protein cysteine methyltransferase
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  2    [I]    COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  2    [C]    COG0372 Citrate synthase
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  2    [R]    COG0385 Predicted Na+-dependent transporter
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  2    [G]    COG0406 Fructose-2,6-bisphosphatase
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  2    [Q]    COG0412 Dienelactone hydrolase and related enzymes
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  2    [D]    COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  2    [O]    COG0425 Predicted redox protein, regulator of disulfide bond formation
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  2    [E]    COG0440 Acetolactate synthase, small (regulatory) subunit
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  2    [E    P]    COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  2    [R]    COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  2    [O]    COG0450 Peroxiredoxin
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  2    [R]    COG0456 Acetyltransferases
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2    [E]    COG0460 Homoserine dehydrogenase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  2    [G]    COG0469 Pyruvate kinase
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  2    [M]    COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  2    [P]    COG0474 Cation transport ATPase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  2    [P]    COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  2    [H]    COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  2    [C]    COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  2    [D]    COG0489 ATPases involved in chromosome partitioning
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  2    [F]    COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  2    [L]    COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  2    [C]    COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [E    H]    COG0512 Anthranilate/para-aminobenzoate synthases component II
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  2    [F]    COG0518 GMP synthase - Glutamine amidotransferase domain
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  2    [E]    COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  2    [H]    COG0521 Molybdopterin biosynthesis enzymes
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  2    [R]    COG0523 Putative GTPases (G3E family)
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  2    [F    G    R]    COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
-------------||---||-||||-|---------------||||||||||||||-------|--  2    [O]    COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  2    [E]    COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  2    [E]    COG0548 Acetylglutamate kinase
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  2    [E]    COG0549 Carbamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0550 Topoisomerase IA
|||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||-------  2    [L]    COG0551 Zn-finger domain associated with topoisomerase type I
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  2    [O]    COG0555 ABC-type sulfate transport system, permease component
||||||--||-||-----||-|--------------------|||||-||||||||---|||||-|  2    [J]    COG0565 rRNA methylase
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  2    [C]    COG0578 Glycerol-3-phosphate dehydrogenase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  2    [G]    COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  2    [C]    COG0584 Glycerophosphoryl diester phosphodiesterase
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  2    [E    R]    COG0591 Na+/proline symporter
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0593 ATPase involved in DNA replication initiation
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  2    [P]    COG0598 Mg2+ and Co2+ transporters
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  2    [O]    COG0602 Organic radical activating enzymes
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  2    [C    R]    COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  2    [P]    COG0605 Superoxide dismutase
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  2    [J]    COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||----  2    [P]    COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  2    [J]    COG0621 2-methylthioadenine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0629 Single-stranded DNA-binding protein
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  2    [O]    COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  2    [I]    COG0657 Esterase/lipase
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  2    [G]    COG0662 Mannose-6-phosphate isomerase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  2    [R]    COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  2    [T]    COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
-|||||||-|||----||||-|---|-||-------------|||-|-----|---||--------  2    [L]    COG0675 Transposase and inactivated derivatives
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||---  2    [E]    COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  2    [E]    COG0687 Spermidine/putrescine-binding periplasmic protein
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  2    [E]    COG0703 Shikimate kinase
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  2    [O]    COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  2    [P]    COG0725 ABC-type molybdate transport system, periplasmic component
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  2    [P]    COG0735 Fe2+/Zn2+ uptake regulation proteins
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  2    [O]    COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
----------------||||||||------||||||||----||||||||||||||||||||||||  2    [I]    COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2    [D]    COG0772 Bacterial cell division membrane protein
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2    [M]    COG0773 UDP-N-acetylmuramate-alanine ligase
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  2    [F]    COG0775 Nucleoside phosphorylase
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  2    [M]    COG0787 Alanine racemase
-----------------|||||||||----------------|||||-||||||||||||||||||  2    [R]    COG0795 Predicted permeases
----------------||||||---|----||||||||----||||||||||||||||||||||||  2    [J]    COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
|-|------|------|-||||||------------------|||||-||||||||||||||||||  2    [U]    COG0811 Biopolymer transport proteins
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  2    [R]    COG0824 Predicted thioesterase
-------------||---------------||--|||-----|||||--|-----|||--------  2    [E]    COG0833 Amino acid transporters
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  2    [N    T]    COG0835 Chemotaxis signal transduction protein
--||--|||-------||||-|--------|-----------|||||-||--|---||-|||||-|  2    [M]    COG0836 Mannose-1-phosphate guanylyltransferase
----------------|-||||||------------------|||||-||||||||||||||||||  2    [U]    COG0848 Biopolymer transport protein
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  2    [L]    COG0863 DNA modification methylase
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  2    [E]    COG1045 Serine acetyltransferase
|||||||||||||-------||--|-----------------|||||-|||||||||||-------  2    [O]    COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  2    [C    H    R]    COG1052 Lactate dehydrogenase and related dehydrogenases
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  2    [R]    COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
--|||||||-||||||---|||--|-|||||-||||------|||||-|-----------------  2    [K    L]    COG1061 DNA or RNA helicases of superfamily II
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  2    [R]    COG1064 Zn-dependent alcohol dehydrogenases
--------------------||||-||---||||||||-|||||||||||||||||------||--  2    [G]    COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  2    [M]    COG1088 dTDP-D-glucose 4,6-dehydratase
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  2    [R]    COG1092 Predicted SAM-dependent methyltransferases
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  2    [E]    COG1115 Na+/alanine symporter
------------------||-------||--------|----|||||-||--||||||||||||--  2    [P]    COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  2    [P]    COG1121 ABC-type Mn/Zn transport systems, ATPase component
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  2    [P]    COG1122 ABC-type cobalt transport system, ATPase component
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  2    [R]    COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  2    [E]    COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  2    [P]    COG1135 ABC-type metal ion transport system, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  2    [V]    COG1136 ABC-type antimicrobial peptide transport system, ATPase component
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2    [C]    COG1140 Nitrate reductase beta subunit
|||||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  2    [C]    COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
---|--------------||------||||-|--|||-----|||||-||||---------|----  2    [H    Q]    COG1169 Isochorismate synthase
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  2    [G]    COG1175 ABC-type sugar transport systems, permease components
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  2    [E]    COG1176 ABC-type spermidine/putrescine transport system, permease component I
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  2    [M]    COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  2    [D]    COG1192 ATPases involved in chromosome partitioning
||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|--  2    [K    L]    COG1199 Rad3-related DNA helicases
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  2    [M]    COG1209 dTDP-glucose pyrophosphorylase
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  2    [M]    COG1210 UDP-glucose pyrophosphorylase
|-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||--  2    [R]    COG1216 Predicted glycosyltransferases
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  2    [R]    COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  2    [I]    COG1250 3-hydroxyacyl-CoA dehydrogenase
--------------------|----|------|||-||----|||-|---|------------|--  2    [S]    COG1288 Predicted membrane protein
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  2    [S]    COG1295 Predicted membrane protein
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  2    [C]    COG1301 Na+/H+-dicarboxylate symporters
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  2    [C]    COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2    [M]    COG1346 Putative effector of murein hydrolase
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  2    [S]    COG1359 Uncharacterized conserved protein
----------------||------||----|----|||----|||||-||-----|||||||||--  2    [N]    COG1360 Flagellar motor protein
----------------||----||||----|----|||----||||||||-----|||||||||--  2    [N    U]    COG1377 Flagellar biosynthesis pathway, component FlhB
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  2    [R]    COG1380 Putative effector of murein hydrolase LrgA
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2    [P]    COG1393 Arsenate reductase and related proteins, glutaredoxin family
-||-----|-------|--|-|--------|--|--------|||-|---------------|---  2    [O]    COG1397 ADP-ribosylglycohydrolase
-----------------|---|-|--||||||||||||----|||||-|-||--------------  2    [K]    COG1438 Arginine repressor
---------------------------------|--|-----|||-|---||----||--|---||  2    [M]    COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
-------------||-----|-||------------------|||||-||||||||----|-|---  2    [E]    COG1448 Aspartate/tyrosine/aromatic aminotransferase
----------------|---|-||------------------|||||-||--|--|--|---||--  2    [N    U]    COG1450 Type II secretory pathway, component PulD
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2    [P]    COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  2    [G]    COG1472 Beta-glucosidase-related glycosidases
-----------------|------------|----|||----|||||-|----------||-|---  2    [G]    COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
-||---|||-||------||-|-----||-----------------|---|-|--|---||-||-|  2    [R]    COG1487 Predicted nucleic acid-binding protein, contains PIN domain
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  2    [G]    COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
|-|-----|------|-|--------|||-|---|--||---|||||-|-||----|||-------  2    [P]    COG1528 Ferritin-like protein
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  2    [J]    COG1530 Ribonucleases G and E
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  2    [J]    COG1544 Ribosome-associated protein Y (PSrp-1)
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  2    [R]    COG1546 Uncharacterized protein (competence- and mitomycin-induced)
|||------|-------|------------------------||||||||||--------------  2    [P]    COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction
-------------|||---|----||----------------|||-|--|-----|----------  2    [G]    COG1626 Neutral trehalase
-------------|||-----|--|||---------------|||||-||||||||---|||||--  2    [L]    COG1643 HrpA-like helicases
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  2    [V]    COG1680 Beta-lactamase class C and other penicillin binding proteins
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  2    [T]    COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  2    [M]    COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
||-----||--------||||---|--||-|-----------|||-|--|--||||-------|--  2    [C]    COG1773 Rubredoxin
------|||----------------------|----|-----|||||----|---|--|||-||--  2    [M]    COG1794 Aspartate racemase
-------------------------|--------|-|-----|||||-|-||------|-------  2    [R]    COG1823 Predicted Na+/dicarboxylate symporter
||||--||||-||---|--|--||------------------|||||----|-------||-|---  2    [G]    COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  2    [P]    COG1840 ABC-type Fe3+ transport system, periplasmic component
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  2    [K    T]    COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  2    [R]    COG1881 Phospholipid-binding protein
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  2    [H]    COG1893 Ketopantoate reductase
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  2    [C]    COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  2    [S]    COG1937 Uncharacterized protein conserved in bacteria
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  2    [F]    COG1957 Inosine-uridine nucleoside N-ribohydrolase
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  2    [K]    COG1959 Predicted transcriptional regulator
--|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||-------  2    [T]    COG1966 Carbon starvation protein, predicted membrane protein
----------------|-------------------------|||-|---------|||-------  2    [C]    COG1969 Ni,Fe-hydrogenase I cytochrome b subunit
|||---||||--|-----------------|---||||----|||||--|-|--------------  2    [R]    COG1988 Predicted membrane-bound metal-dependent hydrolases
----------------|-|||----------------|----|||||-||-|||||||||||||--  2    [H]    COG1995 Pyridoxal phosphate biosynthesis protein
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2    [P]    COG2011 ABC-type metal ion transport system, permease component
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  2    [G]    COG2017 Galactose mutarotase and related enzymes
-||---|-|---|-----|||------||----|--------|--||-|------|---||-----  2    [J    D]    COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system
----------------|---------|||-||-|||||-|--|||||-||||---||||-------  2    [O]    COG2077 Peroxiredoxin
-------------||---||----------|---|-||----|||-|---|||--|----------  2    [H]    COG2091 Phosphopantetheinyl transferase
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  2    [S]    COG2128 Uncharacterized conserved protein
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  2    [Q]    COG2132 Putative multicopper oxidases
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  2    [M]    COG2148 Sugar transferases involved in lipopolysaccharide synthesis
---|-------------|||-------||----||-------|||-|-|----------|-----|  2    [D]    COG2161 Antitoxin of toxin-antitoxin stability system
------------------||-|||---||-------------|||||-|||||------|||||--  2    [R]    COG2166 SufE protein probably involved in Fe-S center assembly
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2    [C]    COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  2    [C]    COG2181 Nitrate reductase gamma subunit
--------------------|----||---||||||||-|||||||||||||---|-------|--  2    [G]    COG2190 Phosphotransferase system IIA components
--|-----------------||---|----||||||||----|||||-|-||------|-|--|--  2    [E]    COG2195 Di- and tripeptidases
-|------------------|---|-----------------|||||---||---|---||||---  2    [R]    COG2215 ABC-type uncharacterized transport system, permease component
----------------|---------||||----|-||----|||-|--|-----|----||-|--  2    [P]    COG2223 Nitrate/nitrite transporter
-------------||------|---||---|-|---------|||||--|||-------|||||--  2    [H]    COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  2    [S]    COG2246 Predicted membrane protein
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  2    [R]    COG2252 Permeases
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  2    [S]    COG2261 Predicted membrane protein
------------------||----------||-|--||||||-||||-||--||||----|-||--  2    [V]    COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
--------------------||----|----|||-||-----|||||--|-----|---|--||--  2    [S]    COG2315 Uncharacterized protein conserved in bacteria
--|------------------|--------------------|||||-|||||------|||||||  2    [O]    COG2332 Cytochrome c-type biogenesis protein CcmE
----||---------------|----|||-----||------|||||-||--|||||||||-||--  2    [S]    COG2353 Uncharacterized conserved protein
---------------------|----|---|---||||----|||-|--|----------------  2    [P]    COG2382 Enterochelin esterase and related enzymes
--|-----|------------|--------------------|||||-|||||------|||||--  2    [O]    COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component
----||----|||----|--|---------------------|||-|-------------|-|---  2    [C]    COG2440 Ferredoxin-like protein
----||||--||--------------|---||||||||----|||||-|----------||--|--  2    [G]    COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  2    [J]    COG2813 16S RNA G1207 methylase RsmC
---------------------|--------|-----------|||||-||||-|||----|---||  2    [R]    COG2823 Predicted periplasmic or secreted lipoprotein
------------------------|-----------------||||||||||||||---|||||--  2    [S]    COG2840 Uncharacterized protein conserved in bacteria
---|------||---------|----|----||---||----|||||-||||---|--||||||--  2    [S]    COG2860 Predicted membrane protein
--|-----|-------|-------------------------|||||-||||---|--|-|-----  2    [C]    COG2864 Cytochrome b subunit of formate dehydrogenase
------------------------------------------|||||--|---|||--|-------  2    [S]    COG2879 Uncharacterized small protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG2890 Methylase of polypeptide chain release factors
------------------------------------------|||||||-|||--|----------  2    [R]    COG2916 DNA-binding protein H-NS
--------------------|----------||-|--------|--|--||||||----|||||--  2    [K]    COG2932 Predicted transcriptional regulator
-------------------|-|--------------------|||||-|-||--------------  2    [S]    COG2949 Uncharacterized membrane protein
--------------------------|-------||||----|||||-||||---|---|||||--  2    [R]    COG2962 Predicted permeases
------------------------------------------|||||-||---|||----|||-||  2    [M]    COG2982 Uncharacterized protein involved in outer membrane biogenesis
---|----------------|-----|---------------|||||-|-||--------------  2    [R]    COG2985 Predicted permease
------------------------------------------|||||-|-||-||---|---|---  2    [S]    COG2990 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-|||----------  2    [S]    COG2995 Uncharacterized paraquat-inducible protein A
------------------------------------------|||||-||||------|||-----  2    [C]    COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
------------------------------------------|||||-||||-|||----------  2    [R]    COG3008 Paraquat-inducible protein B
--------------------|----||----|||||---|--|||||-|-||---------|----  2    [G]    COG3010 Putative N-acetylmannosamine-6-phosphate epimerase
--------------------|---------------------|||||-||||||||---|||||-|  2    [V]    COG3023 Negative regulator of beta-lactamase expression
----------------|-------------------------|||||-||------|||||||---  2    [S]    COG3034 Uncharacterized protein conserved in bacteria
--------|---------------------------------|||||-|----|||------|---  2    [R]    COG3042 Putative hemolysin
--------------------|----------||---------|||-|-|-|---------------  2    [C]    COG3051 Citrate lyase, alpha subunit
--------------------|----------||---------|||-|-|-|---------------  2    [C]    COG3052 Citrate lyase, gamma subunit
--------------------|----------||---------|||-|-|-|---------------  2    [C]    COG3053 Citrate lyase synthetase
--------------------|-----------||--------|||||-|-|-|------||----|  2    [L]    COG3077 DNA-damage-inducible protein J
------------------------------------------|||||-||||--------------  2    [U]    COG3114 Heme exporter protein D
------------------------------------------|||-|-||--|--|----------  2    [P]    COG3131 Periplasmic glucans biosynthesis protein
------------------------------------------|||||-||-|---|----------  2    [R]    COG3150 Predicted esterase
-------------------------------|--||------|||||-||----------|-||--  2    [S]    COG3152 Predicted membrane protein
---------------------|------------------------|--||---------|-----  2    [R]    COG3179 Predicted chitinase
--------------------------|----|||--------|||||--|||----||--------  2    [H]    COG3201 Nicotinamide mononucleotide transporter
--|---------------------------|----||-----|||||--|-----|------|---  2    [M]    COG3209 Rhs family protein
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  2    [S]    COG3238 Uncharacterized protein conserved in bacteria
-------------------|--------------------------|-||-||--|----------  2    [I    R]    COG3240 Phospholipase/lecithinase/hemolysin
------------------|-----------------------|||||--|||---|---|||||--  2    [M]    COG3264 Small-conductance mechanosensitive channel
-------------||----|-|----|---------------|||||-||-|-|||---||-|---  2    [G]    COG3265 Gluconate kinase
--|-|------|--|---------------|-----------|||||--|-|---|-------|--  2    [S]    COG3384 Uncharacterized conserved protein
------------------|||----------------|----|--||---||-------||||---  2    [S]    COG3395 Uncharacterized protein conserved in bacteria
------------------------------|----|||----|||-|--------|------||--  2    [L]    COG3449 DNA gyrase inhibitor
-------------------|-----------------------||||--|--|--|---|--|---  2    [R]    COG3497 Phage tail sheath protein FI
-------------------------------------------||-|--|--|--|----------  2    [R]    COG3498 Phage tail tube protein FII
-------------------|----------------------|||-|--|--|--|---|--|---  2    [R]    COG3500 Phage protein D
----------------|-------|-----------------|||-|-||-----|----|-|---  2    [K    T]    COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
---------------------------------|--------|||||---||-||-----------  2    [P]    COG3615 Uncharacterized protein/domain, possibly involved in tellurite resistance
--------------------------|---------------|||||--|||---|----|||---  2    [G]    COG3622 Hydroxypyruvate isomerase
--------------------------------||-----||-|||||-|-||--------------  2    [G]    COG3623 Putative L-xylulose-5-phosphate 3-epimerase
-------------------|-------------------------||--|--|--|------|---  2    [R]    COG3628 Phage baseplate assembly protein W
-------------------|----------------------|||-|--|---------||-|---  2    [S]    COG3685 Uncharacterized protein conserved in bacteria
--------------------|-----------|---------|||-|-|-|---------------  2    [H    I]    COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase)
--------------------|-----|---||||||||----|||||-------------------  2    [K]    COG3711 Transcriptional antiterminator
-----------------------------------|-|----|||-|----|----------|---  2    [G]    COG3730 Phosphotransferase system sorbitol-specific component IIC
-----------------------------------|-|----|||-|----|----------|---  2    [G]    COG3731 Phosphotransferase system sorbitol-specific component IIA
-----------------------------------|-|----||--|----|----------|---  2    [G]    COG3732 Phosphotransferase system sorbitol-specific component IIBC
--------------|-------------------------------|--|-----|---|||||--  2    [S]    COG3791 Uncharacterized conserved protein
----------------|-------------|----|||----|||-|--|-----|----------  2    [K    T]    COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  2    [G]    COG3839 ABC-type sugar transport systems, ATPase components
------------------------------------------|||||-||||-|||----------  2    [T]    COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific
----------------------------------------------|--|--|--|----------  2    [R]    COG3948 Phage-related baseplate assembly protein
----------------------------------------------|-|-----------|-----  2    [R]    COG3950 Predicted ATP-binding protein involved in virulence
--------------------------|--------|||-------||--------|---|||||--  2    [E]    COG3962 Acetolactate synthase
----------------------------------------------|------------|--|---  2    [R]    COG3964 Predicted amidohydrolase
---|---------------------------|---|-|-------||-||----------------  2    [R]    COG3979 Uncharacterized protein contain chitin-binding domain type 3
------------------------------------------|||||-|||||------|||||||  2    [O]    COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component
------------------------------------------|||||-||||-------||-|---  2    [E]    COG4160 ABC-type arginine/histidine transport system, permease component
------------------------------------------|||||-||||-------||-|---  2    [E]    COG4215 ABC-type arginine transport system, permease component
----------------------||------------------|||||-||||||||--|----|--  2    [O    C]    COG4232 Thiol:disulfide interchange protein
------------------------------------------|||||-|-------------|---  2    [M]    COG4238 Murein lipoprotein
----------------------------------------------|--|--|--|---|------  2    [R]    COG4385 Bacteriophage P2-related tail formation protein
------------------|---------------------------|---|-|-------|-||--  2    [S]    COG4456 Virulence-associated protein and related proteins
---------------------------------------------||--|--|--|----------  2    [R]    COG4540 Phage P2 baseplate assembly protein gpV
------------------|||--------------|------|||-|-------------------  2    [Q    C]    COG4576 Carbon dioxide concentrating mechanism/carboxysome shell protein
--|-------------|---||--||----|-----------||||||||||||||||||||||||  2    [M]    COG4591 ABC-type transport system, involved in lipoprotein release, permease component
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  2    [E]    COG4608 ABC-type oligopeptide transport system, ATPase component
--|--------------|--|---||---------|------||||||||||--------------  2    [C]    COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC
----------------------||-------------------||||--|-----|------|---  2    [U]    COG4669 Type III secretory pathway, lipoprotein EscJ
----------------------||-------------------||||--|-----|------|---  2    [U]    COG4789 Type III secretory pathway, component EscV
-------------------------------------------||||--|-----|------|---  2    [U]    COG4790 Type III secretory pathway, component EscR
----------------------||-------------------||||--|-----|------|---  2    [U]    COG4791 Type III secretory pathway, component EscT
----------------------||-------------------||||--|-----|------|---  2    [U]    COG4794 Type III secretory pathway, component EscS
----------------------------------||------|||-|-------------------  2    [S]    COG4808 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|-------------------  2    [E]    COG4810 Ethanolamine utilization protein
--------------------|--------------|------|||-|-------------------  2    [E]    COG4816 Ethanolamine utilization protein
--|----------|||---|----------|-|--|------|||||--|-----|----------  2    [S]    COG4886 Leucine-rich repeat (LRR) protein
--------------------|--------------|------|||-|-------------------  2    [E]    COG4917 Ethanolamine utilization protein
------------------------------------------|||-|--|--|--------|----  2    [T]    COG4943 Predicted signal transduction protein containing sensor and EAL domains
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2    [C]    COG5013 Nitrate reductase alpha subunit
|||---|-|-------||--|---|-------|-------------|-||-|------|-------  2    [C]    COG5016 Pyruvate/oxaloacetate carboxyltransferase
----------------------------------------------|--|-----|----------  2    [R]    COG5301 Phage-related tail fibre protein
----------------------------------------------|------------|--|---  2    [S]    COG5426 Uncharacterized membrane protein
------------------------------------------|||||------------|---|--  2    [S]    COG5463 Predicted integral membrane protein
-------------------------------------------|--|--------|-----|-|-|  2    [S]    COG5510 Predicted small secreted protein
------------------------------------------|||-|--|-||-------------  2    [N]    COG5571 Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion
------------------------------------------|||||--|||--------------  2    [R]    COG5645 Predicted periplasmic lipoprotein
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  1    [H]    COG0001 Glutamate-1-semialdehyde aminotransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1    [E]    COG0002 Acetylglutamate semialdehyde dehydrogenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1    [P]    COG0004 Ammonia permease
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  1    [F]    COG0005 Purine nucleoside phosphorylase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  1    [H]    COG0007 Uroporphyrinogen-III methylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1    [E]    COG0014 Gamma-glutamyl phosphate reductase
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1    [F]    COG0015 Adenylosuccinate lyase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||--||||--||----|||||||||||||||||||-|||-------------  1    [J]    COG0017 Aspartyl/asparaginyl-tRNA synthetases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0018 Arginyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1    [I]    COG0020 Undecaprenyl pyrophosphate synthase
|||||||||||||||---||----------------------|||||-||||--------------  1    [J]    COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1    [J]    COG0024 Methionine aminopeptidase
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  1    [P]    COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1    [F]    COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
-|----||---|------||------|||-------|-----|||||-||-|--------------  1    [F]    COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  1    [H]    COG0029 Aspartate oxidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0030 Dimethyladenosine transferase (rRNA methylation)
-------------||---|--|----|||-------------|||||-|----------|||||--  1    [G]    COG0033 Phosphoglucomutase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1    [F]    COG0035 Uracil phosphoribosyltransferase
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  1    [C]    COG0039 Malate/lactate dehydrogenases
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1    [E]    COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  1    [F]    COG0044 Dihydroorotase and related cyclic amidohydrolases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1    [C]    COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0049 Ribosomal protein S7
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1    [P]    COG0053 Predicted Co/Zn/Cd cation transporters
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0054 Riboflavin synthase beta-chain
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0056 F0F1-type ATP synthase, alpha subunit
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E    H]    COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1    [G]    COG0061 Predicted sugar kinase
|||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||--  1    [S]    COG0062 Uncharacterized conserved protein
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1    [G]    COG0063 Predicted sugar kinase
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0067 Glutamate synthase domain 1
|||---||||------|-||----------|-----------|||-|---------|||-------  1    [O]    COG0068 Hydrogenase maturation factor
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0069 Glutamate synthase domain 2
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0070 Glutamate synthase domain 3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0072 Phenylalanyl-tRNA synthetase beta subunit
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  1    [E]    COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1    [E]    COG0077 Prephenate dehydratase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0082 Chorismate synthase
-|-|||||-||||||-||||-|----||||||-|||||----|||||||-|||---|||-------  1    [E]    COG0083 Homoserine kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0094 Ribosomal protein L5
---|||||---||||-||||--||--|----|||||||-||||||||-||----------------  1    [H]    COG0095 Lipoate-protein ligase A
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1    [J]    COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1    [F]    COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1    [F]    COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0107 Imidazoleglycerol-phosphate synthase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1    [O]    COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  1    [E]    COG0112 Glycine/serine hydroxymethyltransferase
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1    [H]    COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1    [C]    COG0114 Fumarase
-|----|||||-|-----|-||--------||||||||----||||||||||||||----------  1    [L]    COG0116 Predicted N6-adenine-specific DNA methylase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0117 Pyrimidine deaminase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0118 Glutamine amidotransferase
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  1    [E]    COG0119 Isopropylmalate/homocitrate/citramalate synthases
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1    [G]    COG0120 Ribose 5-phosphate isomerase
||--|-||--||-|----||-------||-------------|||||-||||-|||---||||---  1    [R]    COG0121 Predicted glutamine amidotransferase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  1    [L]    COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1    [F]    COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0128 5-enolpyruvylshikimate-3-phosphate synthase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1    [J]    COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0131 Imidazoleglycerol-phosphate dehydratase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1    [E]    COG0135 Phosphoribosylanthranilate isomerase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1    [F]    COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0143 Methionyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0148 Enolase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0149 Triosephosphate isomerase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1    [F]    COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1    [F]    COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
------|---|--||--|--|---|-|||-||-|--||----|||||-|-||--------------  1    [G]    COG0153 Galactokinase
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  1    [P]    COG0155 Sulfite reductase, beta subunit (hemoprotein)
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  1    [H]    COG0157 Nicotinate-nucleotide pyrophosphorylase
---|---------||---||----------------------|||||-||||-||||||-||-|--  1    [G]    COG0158 Fructose-1,6-bisphosphatase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0159 Tryptophan synthase alpha chain
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  1    [E]    COG0160 4-aminobutyrate aminotransferase and related aminotransferases
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  1    [H]    COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0162 Tyrosyl-tRNA synthetase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1    [G]    COG0166 Glucose-6-phosphate isomerase
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  1    [P]    COG0168 Trk-type K+ transport systems, membrane components
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1    [H]    COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0173 Aspartyl-tRNA synthetase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  1    [E]    COG0174 Glutamine synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1    [L]    COG0177 Predicted EndoIII-related endonuclease
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0178 Excinuclease ATPase subunit
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1    [H]    COG0181 Porphobilinogen deaminase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0186 Ribosomal protein S17
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1    [H]    COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1    [H]    COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1    [H]    COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0203 Ribosomal protein L17
-------------||||||||||||||||||||||||||||||||||||-|||------||-|---  1    [G]    COG0205 6-phosphofructokinase
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1    [D]    COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1    [F]    COG0207 Thymidylate synthase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1    [H]    COG0212 5-formyltetrahydrofolate cyclo-ligase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  1    [F]    COG0213 Thymidine phosphorylase
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0216 Protein chain release factor A
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1    [R]    COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1    [J]    COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1    [C]    COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0222 Ribosomal protein L7/L12
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0224 F0F1-type ATP synthase, gamma subunit
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1    [O]    COG0225 Peptide methionine sulfoxide reductase
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1    [J]    COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1    [O]    COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0230 Ribosomal protein L34
------------------|--|----||||-----|------|||||-||||---|---|||||||  1    [F]    COG0232 dGTP triphosphohydrolase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1    [O]    COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1    [H]    COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0238 Ribosomal protein S18
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  1    [D]    COG0239 Integral membrane protein possibly involved in chromosome condensation
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1    [C]    COG0240 Glycerol-3-phosphate dehydrogenase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0242 N-formylmethionyl-tRNA deformylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1    [I]    COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1    [L]    COG0249 Mismatch repair ATPase (MutS family)
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1    [E]    COG0253 Diaminopimelate epimerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0256 Ribosomal protein L18
-------------||---||-|-----|||------------|||||-|||-||||---|||||--  1    [H]    COG0259 Pyridoxamine-phosphate oxidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0261 Ribosomal protein L21
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  1    [H]    COG0262 Dihydrofolate reductase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1    [E]    COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0264 Translation elongation factor Ts
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0267 Ribosomal protein L33
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0268 Ribosomal protein S20
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  1    [L]    COG0270 Site-specific DNA methylase
---|---------||---||----------------------||||||||||||||---|||||||  1    [T]    COG0271 Stress-induced morphogen (activity unknown)
|--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|---  1    [F]    COG0274 Deoxyribose-phosphate aldolase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1    [H]    COG0276 Protoheme ferro-lyase (ferrochelatase)
---|---------|||--||----------------------||||||||||||||---|||||||  1    [O]    COG0278 Glutaredoxin-related protein
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1    [F]    COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1    [F]    COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1    [H]    COG0285 Folylpolyglutamate synthase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  1    [V]    COG0286 Type I restriction-modification system methyltransferase subunit
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1    [E]    COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1    [E]    COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0292 Ribosomal protein L20
||||||--||---|||--------||----------------||||||||||||||---|||||||  1    [J]    COG0293 23S rRNA methylase
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1    [H]    COG0294 Dihydropteroate synthase and related enzymes
---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||--  1    [F]    COG0295 Cytidine deaminase
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  1    [G]    COG0297 Glycogen synthase
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
|||||||||||||----|------|-----|||||||||||||||||-||||--------------  1    [H]    COG0301 Thiamine biosynthesis ATP pyrophosphatase
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  1    [H]    COG0302 GTP cyclohydrolase I
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  1    [H]    COG0303 Molybdopterin biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0305 Replicative DNA helicase
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  1    [P]    COG0306 Phosphate/sulphate permeases
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0307 Riboflavin synthase alpha chain
--|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||--  1    [E]    COG0308 Aminopeptidase N
|||||||||||||---|-||----------|-----------|||-|---------|||-------  1    [O]    COG0309 Hydrogenase maturation factor
||||----||--------||----------|----|----------|---|----------|----  1    [P]    COG0310 ABC-type Co2+ transport system, permease component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1    [H]    COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1    [H]    COG0315 Molybdenum cofactor biosynthesis enzyme
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1    [H]    COG0320 Lipoate synthase
----------|--||---||-|----||||------------||||||||||||||---|||||||  1    [H]    COG0321 Lipoate-protein ligase B
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1    [L]    COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1    [J]    COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1    [R]    COG0325 Predicted enzyme with a TIM-barrel fold
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  1    [O]    COG0326 Molecular chaperone, HSP90 family
||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||-------  1    [S]    COG0327 Uncharacterized conserved protein
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1    [L]    COG0328 Ribonuclease HI
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1    [I]    COG0331 (acyl-carrier-protein) S-malonyltransferase
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  1    [I]    COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [J]    COG0333 Ribosomal protein L32
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0337 3-dehydroquinate synthetase
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1    [H]    COG0340 Biotin-(acetyl-CoA carboxylase) ligase
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1    [U]    COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  1    [U]    COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  1    [J]    COG0343 Queuine/archaeosine tRNA-ribosyltransferase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1    [S]    COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1    [E]    COG0345 Pyrroline-5-carboxylate reductase
-||-||--||-|------||----------|-----------|||-|-||||-|||||||||||--  1    [C]    COG0348 Polyferredoxin
-------------|----||------|||||-----------|||||-|||||------|||||||  1    [J]    COG0349 Ribonuclease D
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  1    [H]    COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  1    [H]    COG0352 Thiamine monophosphate synthase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1    [L]    COG0353 Recombinational DNA repair protein (RecF pathway)
-------------||-|-||-|----||||------------||||||||||||||---|||||||  1    [R]    COG0354 Predicted aminomethyltransferase related to GcvT
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1    [M]    COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0361 Translation initiation factor 1 (IF-1)
-------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||---  1    [G]    COG0362 6-phosphogluconate dehydrogenase
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  1    [G]    COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1    [G]    COG0364 Glucose-6-phosphate 1-dehydrogenase
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  1    [E]    COG0367 Asparagine synthase (glutamine-hydrolyzing)
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1    [H]    COG0368 Cobalamin-5-phosphate synthase
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  1    [P]    COG0369 Sulfite reductase, alpha subunit (flavoprotein)
|||---|||||-----||||-|--------||--||------|||||-||--|--||||----|--  1    [P]    COG0370 Fe2+ transport system protein B
||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||-------  1    [H]    COG0373 Glutamyl-tRNA reductase
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  1    [P]    COG0376 Catalase (peroxidase I)
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  1    [O    K]    COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  1    [H]    COG0379 Quinolinate synthase
|---||----|--|||--|-------||||------------|||-|--------|----|-|---  1    [G]    COG0380 Trehalose-6-phosphate synthase
||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----||  1    [M]    COG0381 UDP-N-acetylglucosamine 2-epimerase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  1    [H]    COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  1    [R]    COG0384 Predicted epimerase, PhzC/PhzF homolog
-------------|||--|-|-----|---|||||||||---|||||--|--||||-------|--  1    [O]    COG0386 Glutathione peroxidase
-------------||---||-|----||||------|-----|||||------------||-|---  1    [P]    COG0387 Ca2+/H+ antiporter
-||-------------||||-------||-----|-|-----|||-|--------|----------  1    [R]    COG0390 ABC-type uncharacterized transport system, permease component
||||----||---|--||||-|----||||||||||||----|||||-|--|--------------  1    [S]    COG0391 Uncharacterized conserved protein
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  1    [S]    COG0392 Predicted integral membrane protein
|||||||||--|-----|||-------|||-|---|-|----|||-|-|--|-----------|--  1    [S]    COG0393 Uncharacterized conserved protein
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  1    [T]    COG0394 Protein-tyrosine-phosphatase
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  1    [G]    COG0395 ABC-type sugar transport system, permease component
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  1    [O]    COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
-------------||---||------|----------|----|||-|-||--|--|---||--|--  1    [S]    COG0397 Uncharacterized conserved protein
-------------||---||----------------------|||-|--|---------|------  1    [S]    COG0401 Uncharacterized homolog of Blt101
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  1    [F    R]    COG0402 Cytosine deaminase and related metal-dependent hydrolases
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1    [E]    COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  1    [E]    COG0404 Glycine cleavage system T protein (aminomethyltransferase)
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  1    [E]    COG0405 Gamma-glutamyltransferase
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1    [H]    COG0407 Uroporphyrinogen-III decarboxylase
-------------||---||----------------------|||||-||--|--|---|||||||  1    [H]    COG0408 Coproporphyrinogen III oxidase
|||---||||------|-||----------|-----------|||-|---------|||-------  1    [O]    COG0409 Hydrogenase maturation factor
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1    [E]    COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
-|------|-|||----|||||-----------|--------|||||--|-----|--|||||---  1    [E]    COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1    [H]    COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1    [H]    COG0414 Panthothenate synthetase
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  1    [L]    COG0415 Deoxyribodipyrimidine photolyase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1    [I]    COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||||||||||||---|----------------------|||||-||----------------  1    [L]    COG0417 DNA polymerase elongation subunit (family B)
-------------||---|-----------------------||||||||---||||||||-----  1    [F]    COG0418 Dihydroorotase
||||||||||||||||||||||--||----||--|||-----|||||-||----------------  1    [L]    COG0419 ATPase involved in DNA repair
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  1    [L]    COG0420 DNA repair exonuclease
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  1    [E]    COG0421 Spermidine synthase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  1    [H]    COG0422 Thiamine biosynthesis protein ThiC
|||---|||-------|||||---------|-----------|||-|--|-----|----------  1    [C]    COG0426 Uncharacterized flavoproteins
---|----|----||---|-|-----|---------------|||||--|---------|-|-|--  1    [C]    COG0427 Acetyl-CoA hydrolase
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  1    [P]    COG0428 Predicted divalent heavy-metal cations transporter
-------------|-|--||----------------------|||||-||---|||----------  1    [R]    COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold
||||--|||||||||||--|----------------------|||-|--|-----|----------  1    [A]    COG0430 RNA 3'-terminal phosphate cyclase
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  1    [R]    COG0431 Predicted flavoprotein
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  1    [S]    COG0432 Uncharacterized conserved protein
-|-|--|||||-|-----||----------------------|---|------------|--|---  1    [R]    COG0434 Predicted TIM-barrel enzyme
---|---------||---||------|---------------|||-|-||---------||||---  1    [O]    COG0435 Predicted glutathione S-transferase
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0439 Biotin carboxylase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0442 Prolyl-tRNA synthetase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [D]    COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
---|----|---------||------||||-|--|||-----|||||-|-||--------------  1    [H]    COG0447 Dihydroxynaphthoic acid synthase
-----------------|||||||--||||||-|--||----|||||-|-||-------||-|---  1    [G]    COG0448 ADP-glucose pyrophosphorylase
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1    [H]    COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1    [E    F]    COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1    [O]    COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1    [F]    COG0461 Orotate phosphoribosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  1    [F    E]    COG0462 Phosphoribosylpyrophosphate synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0465 ATP-dependent Zn proteases
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  1    [O]    COG0466 ATP-dependent Lon protease, bacterial type
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0468 RecA/RadA recombinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1    [L]    COG0470 ATPase involved in DNA replication
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  1    [C    E]    COG0473 Isocitrate/isopropylmalate dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0480 Translation elongation factors (GTPases)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  1    [G]    COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [R]    COG0486 Predicted GTPase
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0492 Thioredoxin reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0495 Leucyl-tRNA synthetase
||||----|||-||--||||-||||-----------------|||||-||||||||||||||||--  1    [R]    COG0496 Predicted acid phosphatase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0498 Threonine synthase
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1    [H]    COG0502 Biotin synthase and related enzymes
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1    [F]    COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1    [E    F]    COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1    [E]    COG0506 Proline dehydrogenase
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  1    [E]    COG0509 Glycine cleavage system H protein (lipoate-binding)
-------------||-----|---|------|||||||-||||||||-|-|-----------|---  1    [M]    COG0510 Predicted choline kinase involved in LPS biosynthesis
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  1    [L]    COG0514 Superfamily II DNA helicase
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1    [F]    COG0519 GMP synthase, PP-ATPase domain/subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0525 Valyl-tRNA synthetase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0528 Uridylate kinase
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  1    [P]    COG0529 Adenylylsulfate kinase and related kinases
||||||||||||-||-|||-----||-----------|----|||||-|--|--------|-----  1    [P]    COG0530 Ca2+/Na+ antiporter
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0536 Predicted GTPase
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1    [C]    COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1    [J]    COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1    [F]    COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0541 Signal recognition particle GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  1    [R]    COG0546 Predicted phosphatases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0552 Signal recognition particle GTPase
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  1    [K    L]    COG0553 Superfamily II DNA/RNA helicases, SNF2 family
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  1    [C]    COG0554 Glycerol kinase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1    [K]    COG0557 Exoribonuclease R
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  1    [I]    COG0558 Phosphatidylglycerophosphate synthase
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1    [E]    COG0559 Branched-chain amino acid ABC-type transport system, permease components
|--------------------|----|||||---------|||---|-----------||------  1    [M]    COG0562 UDP-galactopyranose mutase
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0563 Adenylate kinase and related kinases
-------------||------|||--||||----|-||----||||||||||||||---|||||||  1    [C]    COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  1    [P]    COG0569 K+ transport systems, NAD-binding component
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0571 dsRNA-specific ribonuclease
---|---------||--|||-|-|||----|||||||||-|||||||-|-||--------------  1    [F]    COG0572 Uridine kinase
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1    [P]    COG0573 ABC-type phosphate transport system, permease component
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  1    [G]    COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1    [I]    COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0576 Molecular chaperone GrpE (heat shock protein)
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  1    [V]    COG0577 ABC-type antimicrobial peptide transport system, permease component
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  1    [R]    COG0579 Predicted dehydrogenase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1    [P]    COG0581 ABC-type phosphate transport system, permease component
|||||||||||||||||----|--------------------|||||-||||----|||-------  1    [S]    COG0585 Uncharacterized conserved protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0587 DNA polymerase III, alpha subunit
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1    [G]    COG0588 Phosphoglycerate mutase 1
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  1    [F    J]    COG0590 Cytosine/adenosine deaminases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0594 RNase P protein component
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M    U]    COG0597 Lipoprotein signal peptidase
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1    [R]    COG0603 Predicted PP-loop superfamily ATPase
|--------|------||||||---||||-|-----------|||||-||||||||||||||||-|  1    [O]    COG0606 Predicted ATPase with chaperone activity
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1    [L]    COG0608 Single-stranded DNA-specific exonuclease
|||||||||||||---|-||------||||------||----||||||||||||||--|----|--  1    [H]    COG0611 Thiamine monophosphate kinase
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  1    [R]    COG0612 Predicted Zn-dependent peptidases
||||----|--||---||||-|--------|------|----|||||-||||-|||----------  1    [R]    COG0613 Predicted metal-dependent phosphoesterases (PHP family)
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  1    [E]    COG0620 Methionine synthase II (cobalamin-independent)
||||--|||||||||--|--|---|----|||||||||-||||||||-||----------------  1    [R]    COG0622 Predicted phosphoesterase
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  1    [I]    COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1    [R]    COG0627 Predicted esterase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0632 Holliday junction resolvasome, DNA-binding subunit
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1    [F]    COG0634 Hypoxanthine-guanine phosphoribosyltransferase
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  1    [K]    COG0640 Predicted transcriptional regulators
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  1    [N    T]    COG0643 Chemotaxis protein histidine kinase and related kinases
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1    [E]    COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1    [G]    COG0647 Predicted sugar phosphatases of the HAD superfamily
||||||||--||||||||----||---||||---|||||||||||||||-----------------  1    [L]    COG0648 Endonuclease IV
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
|||--|||-|-|-----|---------||-------------|||-|-------------------  1    [C]    COG0650 Formate hydrogenlyase subunit 4
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  1    [C    P]    COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1    [R]    COG0655 Multimeric flavodoxin WrbA
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1    [R]    COG0658 Predicted membrane metal-binding protein
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  1    [P]    COG0659 Sulfate permease and related transporters (MFS superfamily)
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  1    [R]    COG0661 Predicted unusual protein kinase
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1    [H]    COG0669 Phosphopantetheine adenylyltransferase
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1    [C]    COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
-------------|------------|---------------|||||-|||||-------------  1    [G]    COG0676 Uncharacterized enzymes related to aldose 1-epimerase
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  1    [M]    COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  1    [U]    COG0681 Signal peptidase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0682 Prolipoprotein diacylglyceryltransferase
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  1    [H]    COG0684 Demethylmenaquinone methyltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1    [E]    COG0685 5,10-methylenetetrahydrofolate reductase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  1    [I]    COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1    [J]    COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0691 tmRNA-binding protein
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  1    [L]    COG0692 Uracil DNA glycosylase
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1    [O]    COG0694 Thioredoxin-like proteins and domains
--||-----------|--||----------|---|||||||||||||-||------||||------  1    [G]    COG0696 Phosphoglyceromutase
----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-||  1    [G]    COG0698 Ribose 5-phosphate isomerase RpiB
------------------|-----------|-----||----|||-|-||-----|----------  1    [S]    COG0700 Uncharacterized membrane protein
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1    [P]    COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1    [R]    COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0706 Preprotein translocase subunit YidC
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  1    [L]    COG0708 Exonuclease III
-|-------|||----|-------------------------|||||--|||------|-|-----  1    [E]    COG0709 Selenophosphate synthase
||||||-|||||-||-|-----||-------||||||-----|||-|------||-----------  1    [E]    COG0710 3-dehydroquinate dehydratase
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0711 F0F1-type ATP synthase, subunit b
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
--||||------|---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  1    [R]    COG0714 MoxR-like ATPases
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  1    [F]    COG0717 Deoxycytidine deaminase
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1    [S]    COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1    [H]    COG0720 6-pyruvoyl-tetrahydropterin synthase
-|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|---  1    [R]    COG0727 Predicted Fe-S-cluster oxidoreductase
----------------|||||||||||||||-----------||||||||||||||||||||||||  1    [R]    COG0728 Uncharacterized membrane protein, putative virulence factor
----------------|---|---------------------|||||-||||||||---|||||--  1    [M]    COG0729 Outer membrane protein
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  1    [R]    COG0730 Predicted permeases
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  1    [V]    COG0732 Restriction endonuclease S subunits
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1    [I]    COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
-------------|----------------------|-----|||-|---|-|||-|||--|-|--  1    [G]    COG0738 Fucose permease
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1    [L]    COG0742 N6-adenine-specific methylase
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  1    [I]    COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1    [H]    COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1    [M]    COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1    [J]    COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1    [J]    COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||------|----|-------||||----|||||-||||-||||||||||---  1    [P]    COG0753 Catalase
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1    [F]    COG0756 dUTPase
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1    [L    U]    COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1    [S]    COG0759 Uncharacterized conserved protein
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1    [I    M]    COG0761 Penicillin tolerance protein
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  1    [S]    COG0762 Predicted integral membrane protein
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG0763 Lipid A disaccharide synthetase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1    [S]    COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1    [R]    COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0781 Transcription termination factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1    [P]    COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
------------------|-|-----|-------|-------|||||-|||--||-||--------  1    [E]    COG0786 Na+/glutamate symporter
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  1    [F]    COG0788 Formyltetrahydrofolate hydrolase
----------------||||||--|-|||||-----------|||||-||||||||||||||||--  1    [L]    COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1    [M]    COG0793 Periplasmic protease
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1    [M]    COG0796 Glutamate racemase
----------------|-||----||----|-----------|||||-||||||||||||||||||  1    [M]    COG0797 Lipoproteins
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1    [S]    COG0799 Uncharacterized homolog of plant Iojap protein
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  1    [G]    COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1    [H]    COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1    [R]    COG0802 Predicted ATPase or kinase
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  1    [P]    COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1    [U]    COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1    [J]    COG0806 RimM protein, required for 16S rRNA processing
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0807 GTP cyclohydrolase II
----------------|--||---------------------|||||-||||||||||||||||--  1    [M]    COG0810 Periplasmic protein TonB, links inner and outer membranes
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0812 UDP-N-acetylmuramate dehydrogenase
-----------|--------||--|------||||||-|||||||||||-||----||----|---  1    [F]    COG0813 Purine-nucleoside phosphorylase
----------------||||-|||||||||------------|||||-||||-|||||||||||||  1    [M]    COG0815 Apolipoprotein N-acyltransferase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1    [L]    COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------||||||||-||||------------|||||-||||||||||||||||||  1    [L]    COG0817 Holliday junction resolvasome, endonuclease subunit
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1    [M]    COG0818 Diacylglycerol kinase
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1    [R]    COG0820 Predicted Fe-S-cluster redox enzyme
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1    [I]    COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1    [C]    COG0822 NifU homolog involved in Fe-S cluster formation
--|-----|---------||--||------------------|||||-|||||--|||||||||||  1    [U]    COG0823 Periplasmic component of the Tol biopolymer transport system
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1    [J]    COG0828 Ribosomal protein S21
------------------||----------------------|||||--|--||||||-|||||--  1    [G]    COG0837 Glucokinase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
--||||--|--||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1    [C]    COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|--  1    [K]    COG0846 NAD-dependent protein deacetylases, SIR2 family
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1    [D]    COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1    [D]    COG0850 Septum formation inhibitor
------------------||||--------------------||||||||--||||||-||||---  1    [D]    COG0851 Septum formation topological specificity factor
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  1    [H]    COG0853 Aspartate 1-decarboxylase
----------------|-||----------------------|||||-||--||||||||||||--  1    [H]    COG0854 Pyridoxal phosphate biosynthesis protein
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  1    [P]    COG0855 Polyphosphate kinase
---|----|---------||-|-----||-------------||||||||||-||-|||-------  1    [R]    COG0857 BioD-like N-terminal domain of phosphotransacetylase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0858 Ribosome-binding factor A
||||--|||||||-----------------|----|||----|||-|---------||---|-|--  1    [K]    COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
-|||||----|----------|---||---|-----|-|----||-|---|---|-|||----|--  1    [V]    COG1002 Type II restriction enzyme, methylase subunits
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1    [E]    COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  1    [M]    COG1004 Predicted UDP-glucose 6-dehydrogenase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
--||||----------|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  1    [C    P]    COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG1010 Precorrin-3B methylase
|||||||||||||||-|||||---|--||-||--||-|----|||||-|-------|||-------  1    [C]    COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  1    [C]    COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
-----------------|---|--------||||||||-|--|||||||-------||-||-|---  1    [G]    COG1015 Phosphopentomutase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  1    [C]    COG1017 Hemoglobin-like flavoprotein
-------------||----|------||||-||||||-----|||||-||-----|--||-||---  1    [Q]    COG1020 Non-ribosomal peptide synthetase modules and related proteins
---------------------------||-------|-----|||||-||-----------|----  1    [Q]    COG1021 Peptide arylation enzymes
-------------|||------||------------------|||||-||----------------  1    [O]    COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  1    [E]    COG1027 Aspartate ammonia-lyase
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  1    [C]    COG1032 Fe-S oxidoreductase
----------------||||-|-----||-|-----------||||||-|--||||||||||||||  1    [C]    COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1    [R]    COG1040 Predicted amidophosphoribosyltransferases
-|||||||||||-------|----------------------|||||-||---||-----|-|---  1    [C]    COG1042 Acyl-CoA synthetase (NDP forming)
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  1    [C]    COG1048 Aconitase A
------------------||----------------------|||||-||-|||||||||------  1    [C]    COG1049 Aconitase B
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1    [R]    COG1054 Predicted sulfurtransferase
|||||||||-|||-----|--|-----||--|----------|||||---||---|----------  1    [H]    COG1056 Nicotinamide mononucleotide adenylyltransferase
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1    [H]    COG1057 Nicotinic acid mononucleotide adenylyltransferase
||||||--|||-|---||||||||---||||------|----|||||-|-------|||-------  1    [H    R]    COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  1    [C]    COG1062 Zn-dependent alcohol dehydrogenases, class III
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1    [O]    COG1066 Predicted ATP-dependent serine protease
||||||||||-------|------|-----|-----||----|||||-||||--------------  1    [O]    COG1067 Predicted ATP-dependent protease
-------------|--------------------|-||----|||||------------||||---  1    [C]    COG1069 Ribulose kinase
-----|-------||-----------||||-|||-|||----|||||-|-||-------||||---  1    [H]    COG1072 Panthothenate kinase
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1    [L]    COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
|---||--||------||-||-||||----|----|||----|||||-|||||--||||----|||  1    [D]    COG1077 Actin-like ATPase involved in cell morphogenesis
--|---|-|-|--||--|--------||--||----------|||||-|-||--------------  1    [C]    COG1085 Galactose-1-phosphate uridylyltransferase
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  1    [M]    COG1087 UDP-glucose 4-epimerase
|-|-----|-------|-||-------||-|-----------|||-|-||--|---||-|-|||--  1    [M]    COG1089 GDP-D-mannose dehydratase
----||------------||------||||----||||----|||||--||||-------------  1    [R]    COG1090 Predicted nucleoside-diphosphate sugar epimerase
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  1    [M]    COG1091 dTDP-4-dehydrorhamnose reductase
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  1    [E]    COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------|  1    [L]    COG1112 Superfamily I DNA and RNA helicases and helicase subunits
--------------------|-|||-|---|-|||-|-----|||||-||||--------------  1    [E]    COG1114 Branched-chain amino acid permeases
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1    [P]    COG1117 ABC-type phosphate transport system, ATPase component
--|----------||------|----||||-|--||||----|||||----|--------------  1    [P]    COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA
--|--|--------------|-||--------|-|--|||--|||||------------||||---  1    [E    P]    COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
------------------------------------------|||-|-----------|||||---  1    [I]    COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1    [G    M]    COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
----------------||||||||||----------------|||||-||||||||||||||||||  1    [R]    COG1137 ABC-type (unclassified) transport system, ATPase component
||||||-|||||-----|||-|----|||||-----------|||-|-||--|--|||||||||||  1    [C]    COG1146 Ferredoxin
|||----|||-------|--|---------|-----------|||||-------------------  1    [C]    COG1151 6Fe-6S prismane cluster-containing protein
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1    [H    I]    COG1154 Deoxyxylulose-5-phosphate synthase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1    [K]    COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG1160 Predicted GTPases
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  1    [R]    COG1162 Predicted GTPases
---|--------------||------||||-|--|||-----|||||-|-||--------------  1    [H]    COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
------------------||-|--------------------|||||-||-||||-|||-------  1    [E]    COG1166 Arginine decarboxylase (spermidine biosynthesis)
--------------------||----||||||-|-|||----|||||---|----|----------  1    [E]    COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  1    [P]    COG1178 ABC-type Fe3+ transport system, permease component
-------------||-----|---------|---|-||----|||||-|||||||||||-------  1    [H]    COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
-------------------|----------||--||||-||||||||--||----|---||-|---  1    [I]    COG1182 Acyl carrier protein phosphodiesterase
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1    [J]    COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1    [J]    COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  1    [J]    COG1190 Lysyl-tRNA synthetase (class II)
----------------||||--|||--||-|---||||----|||||-||-----||||-------  1    [K]    COG1191 DNA-directed RNA polymerase specialized sigma subunit
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1    [L]    COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1    [L]    COG1195 Recombinational DNA repair ATPase (RecF pathway)
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1    [L    K]    COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [L]    COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1    [L    K]    COG1200 RecG-like helicase
|||---|||-|||---||--|-----------|----|----|||||----|--------------  1    [R]    COG1203 Predicted helicases
----------------||||||----||||||||||||----||||||||||||||||||||||||  1    [M]    COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  1    [M    J]    COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  1    [I]    COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  1    [M]    COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
------------------||||----||||||||||||----||||||||||||||||||||||||  1    [T]    COG1217 Predicted membrane GTPase involved in stress response
-------------||-|-||--||--||||------------|||||||||||-----||||||||  1    [P]    COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1    [O]    COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1    [O]    COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1    [O]    COG1225 Peroxiredoxin
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  1    [Q]    COG1228 Imidazolonepropionase and related amidohydrolases
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  1    [P]    COG1230 Co/Zn/Cd efflux system component
|||---||||-------|------------|---------------|-------------------  1    [R]    COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II
-||------|------|-------------------------|||||-||||||||--||||||||  1    [S]    COG1238 Predicted membrane protein
-|-------|------||--|---------|||-||||----|||||-|-----------------  1    [R]    COG1242 Predicted Fe-S oxidoreductase
--||------------|----|-----|||------||----||||||||-|-|||----------  1    [E]    COG1246 N-acetylglutamate synthase and related acetyltransferases
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  1    [M]    COG1247 Sortase and related acyltransferases
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  1    [C]    COG1251 NAD(P)H-nitrite reductase
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  1    [C]    COG1252 NADH dehydrogenase, FAD-containing subunit
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  1    [C]    COG1254 Acylphosphatases
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1256 Flagellar hook-associated protein
----------------||------------------------||||||||-----|||||||||--  1    [N    O]    COG1261 Flagellar basal body P-ring biosynthesis protein
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  1    [R]    COG1266 Predicted metal-dependent membrane protease
|||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----||  1    [I]    COG1267 Phosphatidylglycerophosphatase A and related proteins
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  1    [H]    COG1270 Cobalamin biosynthesis protein CobD/CbiB
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1    [R]    COG1272 Predicted membrane protein, hemolysin III homolog
-|--|-|||----||-----------|||--||||-------|||-|-|-||-|------------  1    [P]    COG1275 Tellurite resistance protein and related permeases
----------------|----|-------------|||----|||||--------|----|-|---  1    [P]    COG1276 Putative copper export protein
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  1    [R]    COG1279 Lysine efflux permease
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1    [O]    COG1281 Disulfide bond chaperones of the HSP33 family
------------------||-------|||------------|||||-||||-|||---|||||||  1    [C]    COG1282 NAD/NADP transhydrogenase beta subunit
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  1    [P]    COG1283 Na+/phosphate symporter
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  1    [S]    COG1285 Uncharacterized membrane protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1    [R]    COG1286 Uncharacterized membrane protein, required for colicin V production
----------------||------||----|----|||----|||||-||-----|||||||||--  1    [N]    COG1291 Flagellar motor component
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  1    [M]    COG1292 Choline-glycine betaine transporter
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1    [E]    COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1298 Flagellar biosynthesis pathway, component FlhA
----||-----------|------------||----||----|||||---|--------||||---  1    [G]    COG1312 D-mannonate dehydratase
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1    [U]    COG1314 Preprotein translocase subunit SecG
-----------------|----||||----|-----||----||||||||-----||||---|---  1    [N    U]    COG1317 Flagellar biosynthesis/type III secretory pathway protein
|||||||||||||----|---||||-||||||||||||----|||-|-----|---------|---  1    [K]    COG1321 Mn-dependent transcriptional regulator
----------------------||-------|||-----|--|||||-||||||||---|||||||  1    [S]    COG1322 Uncharacterized protein conserved in bacteria
|-|-|||||||-|--|||-|-|-|------------------|||||-----|--|--------||  1    [P]    COG1324 Uncharacterized protein involved in tolerance to divalent cations
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1    [K]    COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
|||---||-|-------|--|---------||||||------|||||-||||---|----------  1    [F]    COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase
----------------------||-|-||-------------|||||||||||||-----------  1    [L]    COG1330 Exonuclease V gamma subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1338 Flagellar biosynthesis pathway, component FliP
----------------||------||----|----|||----|||||-||-----||||-------  1    [N]    COG1345 Flagellar capping protein
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  1    [N    T]    COG1352 Methylase of chemotaxis methyl-accepting proteins
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  1    [G]    COG1363 Cellulase M and related proteins
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  1    [M]    COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1    [L]    COG1381 Recombinational DNA repair protein (RecF pathway)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1    [S]    COG1385 Uncharacterized protein conserved in bacteria
|||-||||||---||-||--||-----||-||--||||----|||||-|-----------|-----  1    [E    R]    COG1387 Histidinol phosphatase and related hydrolases of the PHP family
----------------|---------||||------------|||||-||||-|||---|||||--  1    [O    T]    COG1391 Glutamine synthetase adenylyltransferase
----------------||||-|----||||||||||||----|||||-||||||||----------  1    [R]    COG1399 Predicted metal-binding, possibly nucleic acid-binding protein
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  1    [O]    COG1404 Subtilisin-like serine proteases
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  1    [R]    COG1409 Predicted phosphohydrolases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  1    [E]    COG1410 Methionine synthase I, cobalamin-binding domain
||||||||||------||--||--||----|||||||||-|||||-|---------|||||-----  1    [R]    COG1418 Predicted HD superfamily hydrolase
-----------------|-|--||||-----|||||||----|||||-|||||--|--------||  1    [S]    COG1426 Uncharacterized protein conserved in bacteria
---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|---  1    [F]    COG1435 Thymidine kinase
-------------------------|----||||-|||----|||||-|-----------------  1    [G]    COG1440 Phosphotransferase system cellobiose-specific component IIB
------------------------------------------|||||-|-||--------------  1    [H]    COG1441 O-succinylbenzoate synthase
---|---------|||----------|||-------------|||-|-------------------  1    [I]    COG1443 Isopentenyldiphosphate isomerase
---|--||||||||||--------------------------|||||-|-||--------------  1    [R]    COG1444 Predicted P-loop ATPase fused to an acetyltransferase
---|||||--||--|---||----------------------|||-|-|------|---|---|--  1    [E]    COG1446 Asparaginase
-------------------------|----||||||||----|||||-|-----------------  1    [G]    COG1447 Phosphotransferase system cellobiose-specific component IIA
||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-|  1    [R]    COG1451 Predicted metal-dependent hydrolase
----------------|-------||----------------|||||-||||||||||||||||||  1    [M]    COG1452 Organic solvent tolerance protein OstA
-------------------------|----||||||||----|||||-|-----------------  1    [G]    COG1455 Phosphotransferase system cellobiose-specific component IIC
----||||---|-|---------------------|||----|||-|--|-|-||-----------  1    [F]    COG1457 Purine-cytosine permease and related proteins
----------------||||||||------||||||||----|||||-||||||||------||--  1    [N    U]    COG1459 Type II secretory pathway, component PulF
----------------|-||-|--------------------|||||--|---|||-------|--  1    [M]    COG1462 Uncharacterized protein involved in formation of curli polymers
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG1466 DNA polymerase III, delta subunit
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  1    [H]    COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
--------|----||--|---|---|||||||||||||-|--|||||-|--|--------------  1    [G]    COG1482 Phosphomannose isomerase
-------------||------|-----||-------------|||||-||--||||---|||||||  1    [R]    COG1485 Predicted ATPase
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  1    [H]    COG1488 Nicotinic acid phosphoribosyltransferase
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  1    [R]    COG1489 DNA-binding protein, stimulates sugar fermentation
-------------||-||--||----|||-||||||||----|||||-||||-|||----------  1    [J]    COG1490 D-Tyr-tRNAtyr deacylase
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  1    [H]    COG1492 Cobyric acid synthase
--|---------------||||----|||||-----||----|||-|-|-||---------|||--  1    [G]    COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  1    [S]    COG1496 Uncharacterized conserved protein
----------------|-----||||----|----|||----|||||-||--||||||||||||--  1    [K]    COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
-||-------------||--||--|-----------||----|||||-|-|||------||-||--  1    [E]    COG1509 Lysine 2,3-aminomutase
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  1    [J]    COG1514 2'-5' RNA ligase
---||||||||||-|-||-|-|--------|-----|-----|||||-----|-------------  1    [L]    COG1515 Deoxyinosine 3'endonuclease (endonuclease V)
----------------||------||----|----|||----|||||-||-----||||-------  1    [N    U    O]    COG1516 Flagellin-specific chaperone FliS
|||-|||-|||||---||-||------||---|--|-|----|||||----|--|---|-------  1    [L]    COG1518 Uncharacterized protein predicted to be involved in DNA repair
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1519 3-deoxy-D-manno-octulosonic-acid transferase
||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------|||  1    [S]    COG1520 FOG: WD40-like repeat
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1    [C]    COG1526 Uncharacterized protein required for formate dehydrogenase activity
||||--||||-||-------|---------||||||||----|||||-||||||||----------  1    [J]    COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein
-----------------|------------------|-----|||-|-||-----------|----  1    [Q]    COG1535 Isochorismate hydrolase
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N]    COG1536 Flagellar motor switch protein
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  1    [H]    COG1539 Dihydroneopterin aldolase
------||------------||----|--|----|-||----|||||-|||--|||--||------  1    [R]    COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
-----------------|------||----|-----||----|||||||||||---|||-------  1    [T]    COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing)
--|--------------|||||----|||-||||||||----|||||-||||||||--|-------  1    [L]    COG1555 DNA uptake protein and related DNA-binding proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1    [R]    COG1559 Predicted periplasmic solute-binding protein
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1    [S]    COG1561 Uncharacterized stress-induced protein
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1    [L]    COG1570 Exonuclease VII, large subunit
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  1    [R]    COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
---|-------------||||-----||||-|--|||-----|||||-|-||--------------  1    [H]    COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1    [S]    COG1576 Uncharacterized conserved protein
----------------||------||----|-----||----|||||-||-----||||-------  1    [N]    COG1580 Flagellar basal body-associated protein
|-|-||-----|-||---------------------------|||||-|--|--------------  1    [S]    COG1584 Predicted membrane protein
||-|--||-||||----|||||----|||||-----------|||||-||-||------|||||--  1    [O    U]    COG1585 Membrane protein implicated in regulation of membrane protease activity
-|--|||||-|||---||------------|-----||----||||||-|--|--|----------  1    [E]    COG1586 S-adenosylmethionine decarboxylase
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1    [H]    COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1    [M]    COG1589 Cell division septal protein
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  1    [K]    COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
----------------||||----------------------|||-|-||-|||||--||||||--  1    [M]    COG1596 Periplasmic protein involved in polysaccharide export
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  1    [I    R]    COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1    [C]    COG1600 Uncharacterized Fe-S protein
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  1    [I]    COG1607 Acyl-CoA hydrolase
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  1    [R]    COG1611 Predicted Rossmann fold nucleotide-binding protein
------------------||-------|||-------|----|||||--|--||||---|||||--  1    [P]    COG1613 ABC-type sulfate transport system, periplasmic component
----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------||  1    [V]    COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  1    [C]    COG1620 L-lactate permease
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1    [C]    COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
----------|-----|-||||||-||||--|||--------|||||-||||---|----------  1    [G]    COG1640 4-alpha-glucanotransferase
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1    [H]    COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  1    [S]    COG1652 Uncharacterized protein containing LysM domain
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  1    [G]    COG1653 ABC-type sugar transport system, periplasmic component
--||---||------------|--------||||||||----|||||-|||||-------------  1    [K]    COG1654 Biotin operon repressor
--------------------||----||||||||||||----|||||-||||||||----------  1    [R]    COG1660 Predicted P-loop-containing kinase
|-||||||||--|---------------------|--------||-|-|----------||-|---  1    [R]    COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1663 Tetraacyldisaccharide-1-P 4'-kinase
-------------------|-------||-------||----|||||-||||---|--|-------  1    [S]    COG1666 Uncharacterized protein conserved in bacteria
------------------------||----|---||||----|||||-||---------|||||--  1    [S]    COG1671 Uncharacterized protein conserved in bacteria
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  1    [D]    COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1677 Flagellar hook-basal body protein
---------------------|||--||||------------|||||-||||||||---|||||||  1    [K]    COG1678 Putative transcriptional regulator
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1    [G    M]    COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  1    [S]    COG1683 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1684 Flagellar biosynthesis pathway, component FliR
|||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|----------  1    [S]    COG1690 Uncharacterized conserved protein
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  1    [R]    COG1694 Predicted pyrophosphatase
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  1    [K]    COG1695 Predicted transcriptional regulators
-----------------|-------------||-|||-----|||||-||-----|-----|----  1    [N    U]    COG1705 Muramidase (flagellum-specific)
----------------||-------|----------------||||||||-----|||||||||--  1    [N]    COG1706 Flagellar basal-body P-ring protein
|||---|||||||---||------------|---|-----------|---|--------||----|  1    [R]    COG1708 Predicted nucleotidyltransferases
|-||---------------|-|-----||-------------|---|-------------------  1    [V]    COG1715 Restriction endonuclease
||||--|||||||----|------------------------|||||-||||-||-------||--  1    [S]    COG1720 Uncharacterized conserved protein
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1    [L]    COG1722 Exonuclease VII small subunit
----------------|-------------------------|||||-||--||||---|||||||  1    [S]    COG1729 Uncharacterized protein conserved in bacteria
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  1    [K]    COG1733 Predicted transcriptional regulators
-----------|---------|-----||------|-|-||-|---|------------|--|---  1    [R]    COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  1    [S]    COG1738 Uncharacterized conserved protein
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1    [S]    COG1739 Uncharacterized conserved protein
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  1    [S]    COG1742 Uncharacterized conserved protein
----------------|-------||----|----|------||||||||-----|||||||||--  1    [N]    COG1749 Flagellar hook protein FlgE
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  1    [R]    COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
---|--||----|-------|----|----|---|-||-------||-|-||-||-|||-------  1    [C]    COG1757 Na+/H+ antiporter
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1    [K]    COG1758 DNA-directed RNA polymerase, subunit K/omega
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  1    [H]    COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  1    [O]    COG1764 Predicted redox protein, regulator of disulfide bond formation
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  1    [O]    COG1765 Predicted redox protein, regulator of disulfide bond formation
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
-------------------|------||||---|--------|||||-||--|------|||||||  1    [E]    COG1770 Protease II
--|-------------|---|---------------------|||||-|||||||||||-------  1    [R]    COG1778 Low specificity phosphatase (HAD superfamily)
---------------------|----||||-||||-|--||||||||------------|-|----  1    [F]    COG1780 Protein involved in ribonucleotide reduction
|||||||||||||----|------------|-----------|||||||----||-----------  1    [F]    COG1781 Aspartate carbamoyltransferase, regulatory subunit
----------------|--||-||||----||-|||||----|||||-|||||--||||----|||  1    [M]    COG1792 Cell shape-determining protein
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  1    [H]    COG1797 Cobyrinic acid a,c-diamide synthase
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  1    [S]    COG1801 Uncharacterized conserved protein
-----------------||------|----|----|||----|||||-|-||---|---|||----  1    [G]    COG1803 Methylglyoxal synthase
-----|--|-||---------|-----||-------------|||-|--|-----|---|||||--  1    [C]    COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
---------------------|------------||||----|||||-||--||||---|||||||  1    [S]    COG1806 Uncharacterized protein conserved in bacteria
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  1    [M]    COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
--------|--------|--||--------|----|||----|||-|-------------------  1    [R]    COG1811 Uncharacterized membrane protein, possible Na+ channel or pump
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1815 Flagellar basal body protein
-------------||----|----|--|-|||----------|||-|-||-----|---||-||--  1    [F]    COG1816 Adenosine deaminase
|||------|---|----|--|-----||||-----|------||||-||------------|---  1    [G    C]    COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  1    [G]    COG1820 N-acetylglucosamine-6-phosphate deacetylase
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1    [J]    COG1825 Ribosomal protein L25 (general stress protein Ctc)
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  1    [R]    COG1832 Predicted CoA-binding protein
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  1    [I]    COG1835 Predicted acyltransferases
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1    [J]    COG1841 Ribosomal protein L30/L7E
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1843 Flagellar hook capping protein
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  1    [C]    COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  1    [R]    COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
---------------------|---|----||||||||----|||||-|-||-||-|||-------  1    [T]    COG1854 LuxS protein involved in autoinducer AI2 synthesis
--|-------------|----|--------------------|||||-||-|---|||||--|---  1    [P]    COG1858 Cytochrome c peroxidase
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1    [U]    COG1862 Preprotein translocase subunit YajC
--|----------||----||----|--------------------|--|-----||||----|--  1    [F]    COG1864 DNA/RNA endonuclease G, NUC1
------------||------||------------|-||----|||||-||||------|||||---  1    [C]    COG1866 Phosphoenolpyruvate carboxykinase (ATP)
----------------||------||----|----|||----||||||||-----||||||||---  1    [N]    COG1868 Flagellar motor switch protein
-----------------|--------|----|--|-||-|--|||||-|-||--------------  1    [G]    COG1869 ABC-type ribose transport system, auxiliary component
|||----|||--|------|--||----|-------------|||||-|--|-------|--||||  1    [S]    COG1872 Uncharacterized conserved protein
|---||----|--|||----------||||------------|||-|--------|------|---  1    [G]    COG1877 Trehalose-6-phosphatase
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1    [C]    COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
---|--|||||||||------|------------||------|||||-||-|----||||||||--  1    [R]    COG1896 Predicted hydrolases of HD superfamily
-----------------|------------||-|--||----|||||-|---------||||----  1    [E]    COG1897 Homoserine trans-succinylase
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1    [M]    COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  1    [H]    COG1903 Cobalamin biosynthesis protein CbiD
-----------------|--------|---||----||----|||||-------------||||--  1    [G]    COG1904 Glucuronate isomerase
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1    [C]    COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  1    [P]    COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  1    [S]    COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
|||----|||-------||--|--------||--||------|||||-||--|--|-||----|--  1    [P]    COG1918 Fe2+ transport system protein A
-----------------|||-|--|-----|---|||-----|||||-|---|------|-|||--  1    [M]    COG1922 Teichoic acid biosynthesis proteins
-|--------------||------------|---||||----|||||-||||||||----||||--  1    [R]    COG1923 Uncharacterized host factor I protein
||||----|----------|---------------|----------|-------------------  1    [P]    COG1930 ABC-type cobalt transport system, periplasmic component
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1    [H    E]    COG1932 Phosphoserine aminotransferase
----------------|-||----------------------|||||-||||||||||||||||--  1    [S]    COG1934 Uncharacterized protein conserved in bacteria
||||-----|-----------------||-------------|||||--|||-------||-|---  1    [S]    COG1944 Uncharacterized conserved protein
-------------|-|----------||||------------|||||-|||||------|||||--  1    [I]    COG1946 Acyl-CoA thioesterase
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1    [I]    COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
-------------||-----------||||------------||||||||||||||----------  1    [A]    COG1949 Oligoribonuclease (3'->5' exoribonuclease)
-|----------------------------------------||||||||||||||---|||||||  1    [U]    COG1952 Preprotein translocase subunit SecB
-----------||||---------------------|-----|||||--|-----|----||||--  1    [F    H]    COG1953 Cytosine/uracil/thiamine/allantoin permeases
---|||-------|---|------------||||||||----|||||-||-||||-------||--  1    [T]    COG1956 GAF domain-containing protein
-------------|||--------------------------||||||||||-|||--------||  1    [P]    COG1965 Protein implicated in iron transport, frataxin homolog
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1    [V]    COG1968 Uncharacterized bacitracin resistance protein
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1    [M]    COG1970 Large-conductance mechanosensitive channel
|-|-----------------|-----|---|-----||----|||||--|--|||---|-------  1    [S]    COG1971 Predicted membrane protein
-------------------|------------|-|-||----|||||-|-||----||-----|--  1    [F]    COG1972 Nucleoside permease
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1    [H]    COG1977 Molybdopterin converting factor, small subunit
-----------------|-||---------|----|||----|||||-|--|--------------  1    [C]    COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family
--|---||---------|--------|---||||-|||----|||||-|-----------------  1    [K    T]    COG1983 Putative stress-responsive transcriptional regulator
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  1    [E]    COG1984 Allophanate hydrolase subunit 2
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG1985 Pyrimidine reductase, riboflavin biosynthesis
||--||--|||||------------------------|----|||||-|-----------------  1    [S]    COG1986 Uncharacterized conserved protein
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1987 Flagellar biosynthesis pathway, component FliQ
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  1    [N    O    U]    COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  1    [S]    COG2001 Uncharacterized protein conserved in bacteria
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  1    [L]    COG2003 DNA repair proteins
|-|-----||||------------------------------|||||--|||---|--|||-||--  1    [R]    COG2005 N-terminal domain of molybdenum-binding protein
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  1    [E]    COG2008 Threonine aldolase
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1    [C]    COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  1    [H]    COG2022 Uncharacterized enzyme of thiazole biosynthesis
--|---------------||-|----||||------|-----|||||-||||||||----------  1    [M]    COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  1    [I]    COG2030 Acyl dehydratase
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  1    [H]    COG2038 NaMN:DMB phosphoribosyltransferase
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  1    [R]    COG2041 Sulfite oxidase and related enzymes
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  1    [E]    COG2049 Allophanate hydrolase subunit 1
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1    [P]    COG2060 K+-transporting ATPase, A chain
--------|-|||---|-||------||||------------|||||-|||||--|--||||||--  1    [T]    COG2062 Phosphohistidine phosphatase SixA
----------------||------------------------||||||||-----|||||||||--  1    [N]    COG2063 Flagellar basal body L-ring protein
------------------|||-----|---------||----|||||-||-----|---|||||--  1    [E]    COG2066 Glutaminase
----------------|---|---------------------|||||-|||||||-||-|||||--  1    [I]    COG2067 Long-chain fatty acid transport protein
||-|||--||||------|||---------|----|----------|--|-----|---||||---  1    [H]    COG2073 Cobalamin biosynthesis protein CbiG
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  1    [R]    COG2079 Uncharacterized protein involved in propionate catabolism
------------------||----------||||||||----|||||-||||---|---|||-|--  1    [R]    COG2081 Predicted flavoproteins
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2082 Precorrin isomerase
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1    [H]    COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  1    [S]    COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2099 Precorrin-6x reductase
------------------||-|--------||--|-||----|||||-|-||--------|-|---  1    [R]    COG2103 Predicted sugar phosphate isomerase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  1    [H]    COG2104 Sulfur transfer protein involved in thiamine biosynthesis
-||---|---||------||-|--------------||----|||||-||-----|----------  1    [S]    COG2105 Uncharacterized conserved protein
--||||||--|------|||||-----||-------------|||||-||-----|---||||---  1    [H]    COG2109 ATP:corrinoid adenosyltransferase
--|----------------------|-----||--||-----|||||--|-----|---||||---  1    [E]    COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
-----------------|-------------|----||----|||||---|--------||||---  1    [G]    COG2115 Xylose isomerase
------------------||-|----|||||-----------|||||-||--||||||||||||--  1    [S]    COG2127 Uncharacterized conserved protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  1    [R]    COG2130 Putative NADP-dependent oxidoreductases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  1    [G]    COG2133 Glucose/sorbosone dehydrogenases
---------------------------|||------------|||||---------||--------  1    [I]    COG2134 CDP-diacylglycerol pyrophosphatase
---|---------|-----|------||||------|-----|||-|--|---------||||---  1    [S]    COG2135 Uncharacterized conserved protein
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  1    [R]    COG2137 Uncharacterized protein conserved in bacteria
--|---|||---------|-----------------|---------|--------|---||-|---  1    [G    R]    COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  1    [C]    COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
----||--|---|--------|-----|||------------|||||-||--||||---|||||||  1    [C]    COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
--|---|||----||-----------|---||-|||||----|||-|---||----||-|------  1    [H]    COG2145 Hydroxyethylthiazole kinase, sugar kinase family
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  1    [P    R]    COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
----------------|-||------|||-------------|||-|-------------------  1    [S]    COG2149 Predicted membrane protein
--------------|---|-------|||--|-----|----|||-|-||-----------|----  1    [R]    COG2153 Predicted acyltransferase
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  1    [P]    COG2156 K+-transporting ATPase, c chain
-----------------|------------|-----||----|||||-------------|-----  1    [G]    COG2160 L-arabinose isomerase
---------------------------||-----|-||----|||-|--|------------||--  1    [Q]    COG2162 Arylamine N-acetyltransferase
----------------||||||||------||||||||----|||||-|||||--|--|---||--  1    [N    U]    COG2165 Type II secretory pathway, pseudopilin PulG
|----------------|------------------------||||||||||--------------  1    [P]    COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur
---------------------------||--|---|||----|||||-||-----|---|||||-|  1    [F]    COG2169 Adenosine deaminase
---|--------------||------|||-------------|||-|--|-----|----------  1    [S]    COG2170 Uncharacterized conserved protein
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1    [E]    COG2171 Tetrahydrodipicolinate N-succinyltransferase
------------------||-------||-------------|||-|---------------||--  1    [M]    COG2173 D-alanyl-D-alanine dipeptidase
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  1    [D]    COG2177 Cell division protein
----|-||--|||----|---|---------|||||||----|||||-|----------|------  1    [G]    COG2182 Maltose-binding periplasmic proteins/domains
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1    [K]    COG2183 Transcriptional accessory protein
---------------------------||----|--------|||-|--||-|||-||-||-|---  1    [D]    COG2184 Protein involved in cell division
-----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|---  1    [L]    COG2189 Adenine specific DNA methylase Mod
------------------||-------|||------------|||||-||--||||---|||||--  1    [P]    COG2193 Bacterioferritin (cytochrome b1)
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  1    [N    T]    COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  1    [T]    COG2205 Osmosensitive K+ channel histidine kinase
------------------------------|--|||||-||-|||||||--|--------------  1    [G]    COG2213 Phosphotransferase system, mannitol-specific IIBC component
---|---------|||-|||-|--||----|---------|||||-|-||--|||-||||||||--  1    [O]    COG2214 DnaJ-class molecular chaperone
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  1    [P]    COG2216 High-affinity K+ transport system, ATPase chain B
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  1    [R]    COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
|||-----|||-------------------|---------------|-------------------  1    [C]    COG2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  1    [C]    COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  1    [C]    COG2225 Malate synthase
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1    [H]    COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
-------------||---||-|--------------------|||||-||-|||||---|||||||  1    [H]    COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
--|-------------|----|----|||||-----------|||||-||-----|||||||||--  1    [M]    COG2230 Cyclopropane fatty acid synthase and related methyltransferases
|-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|--  1    [R]    COG2234 Predicted aminopeptidases
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  1    [E]    COG2235 Arginine deiminase
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  1    [H]    COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  1    [H]    COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2243 Precorrin-2 methylase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1    [L]    COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1    [S]    COG2258 Uncharacterized protein conserved in bacteria
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  1    [S]    COG2259 Predicted membrane protein
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1    [R]    COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1    [J]    COG2264 Ribosomal protein L11 methylase
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  1    [I]    COG2267 Lysophospholipase
------------------||------|----|----||----|||-|--|------------|---  1    [S]    COG2268 Uncharacterized protein conserved in bacteria
----------------|-------|-----------------|||||||-|||------||-||--  1    [J]    COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II)
--------------|------|----|||-|---|-|---------|--------|-------|--  1    [I]    COG2272 Carboxylesterase type B
--|-----|--||-----||||---|||||------||----|--||-||------------|---  1    [R]    COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
---|-----------------|----|---------||----|||||-----|----------|--  1    [S]    COG2311 Predicted membrane protein
---------------------|----|||---|---------|||||--|-|---|---||||---  1    [R]    COG2321 Predicted metalloprotease
-------------------|||--------||-|--||----|||-|-------------|-----  1    [S]    COG2323 Predicted membrane protein
|----------------|||-|--------|-----------|||-|------------|-|----  1    [S]    COG2327 Uncharacterized conserved protein
---|---------------|-|--------||||||||----|||||-||||||||----------  1    [R]    COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily)
--|---------------|-||--------------||----|||||-||---|||---|||||--  1    [R]    COG2334 Putative homoserine kinase type II (protein kinase fold)
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  1    [S]    COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  1    [R]    COG2351 Transthyretin-like protein
------------------||-|----|--|--||--------|||||-||||-|||-------|--  1    [C]    COG2352 Phosphoenolpyruvate carboxylase
---------------------|----|||-------------|||-|-||---|-------|-|--  1    [S]    COG2354 Uncharacterized protein conserved in bacteria
---------------------|--------------|-----||||||||----------------  1    [L]    COG2356 Endonuclease I
------------------||-|--------------------|||||-||--||||--||||||--  1    [O]    COG2360 Leu/Phe-tRNA-protein transferase
--------------|----|-|------------||||----|||||-||||-------|||||--  1    [S]    COG2363 Uncharacterized small membrane protein
--------|-||---------|--------------||-------||--|-|--------------  1    [Q]    COG2368 Aromatic ring hydroxylase
---------------------|----|--------|||----|||||--------|----|-|---  1    [R]    COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
-----------------|-|||--------------------|||||--|-||--|---||-||||  1    [R]    COG2373 Large extracellular alpha-helical protein
---------------------|----|||-------------|||-|-||-----|---||-----  1    [P]    COG2375 Siderophore-interacting protein
---------|--------||-|--------------------|||||-||||||||---|||||--  1    [O]    COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
--------------------||----|||||---||||----|---|-||--|-||--||||||--  1    [K]    COG2378 Predicted transcriptional regulator
---------------------|--------||||||||----|||||-|--|---|---||||---  1    [K]    COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  1    [R]    COG2391 Predicted transporter component
------||--|-|----|------------|--|--------|||||---|---------------  1    [G]    COG2407 L-fucose isomerase and related proteins
-||------||||-----------------------------|||||-|-----------------  1    [R]    COG2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------||--|||-------|---------------------|||||-|-||-||-----------  1    [S]    COG2431 Predicted membrane protein
-------------------|||----|---||||||||||--|||||-|----|||----------  1    [S]    COG2501 Uncharacterized conserved protein
--------------------|---|-------||----|---|||||---||--------------  1    [E]    COG2502 Asparagine synthetase A
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  1    [G]    COG2513 PEP phosphonomutase and related enzymes
------||------|--|-|----------------------|||||-|------|--|---||--  1    [E]    COG2515 1-aminocyclopropane-1-carboxylate deaminase
||||--|||||||-|--|------------------------|||||-||--||||||||||||--  1    [O]    COG2518 Protein-L-isoaspartate carboxylmethyltransferase
-|----------------------------------------|||-|--|--------|-------  1    [R]    COG2603 Predicted ATPase
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1    [P]    COG2608 Copper chaperone
---------------------|----||||------------||||||||||||||------||--  1    [C]    COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
--------------|---------------||-||||-----||||||-|-----|----------  1    [G]    COG2706 3-carboxymuconate cyclase
------------------------------|----|||----|||||---||-||-----------  1    [S]    COG2707 Predicted membrane protein
------------------------------------------|||||-||--|----------|--  1    [E]    COG2716 Glycine cleavage system regulatory protein
-------------------|-|--|-----|-----------|||||--|-|---|--||||-|--  1    [S]    COG2717 Predicted membrane protein
---|--------------------------|-----||----|||||-||----------|-|---  1    [S]    COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  1    [S]    COG2719 Uncharacterized conserved protein
------------------------------|-----|-----|||||------|------------  1    [K]    COG2732 Barstar, RNAse (barnase) inhibitor
--------------------------|||-|-----------|||-|-----|---------|---  1    [S]    COG2733 Predicted membrane protein
----------------||------------|-----||----|||||-||-----|----------  1    [K    N    U]    COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor)
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  1    [E]    COG2755 Lysophospholipase L1 and related esterases
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  1    [S]    COG2764 Uncharacterized protein conserved in bacteria
---|--------------------------|-----||----|||||-||----------|-|---  1    [T]    COG2766 Putative Ser protein kinase
----------------||||||||------||||||||----|||||-||||||||--|---||--  1    [N    U]    COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
----------------||||||--------|-----------|||||-||--||||----------  1    [N    U]    COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  1    [P]    COG2807 Cyanate permease
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG2812 DNA polymerase III, gamma/tau subunits
--|----------||------|----|||-|-----------|||||-||||-------|||||--  1    [L]    COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1    [L]    COG2818 3-methyladenine DNA glycosylase
---------------------|--------|--|--|------||-|--|---|----||---|--  1    [R]    COG2819 Predicted hydrolase of the alpha/beta superfamily
---|------|||-----------|----|-||---------|||||-|-||--------------  1    [F]    COG2820 Uridine phosphorylase
------------------||----------------------||||||||||-|||---|||||--  1    [M]    COG2821 Membrane-bound lytic murein transglycosylase
--------------------------|----|||-|------|||||-||||-|||||||||||--  1    [P]    COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
----------------||---|||||----------------|||||-||||-|||-------|||  1    [M]    COG2825 Outer membrane protein
---|----------------|----------|||||||----|||||-||---||-----||||--  1    [L]    COG2827 Predicted endonuclease containing a URI domain
------------------------------------------|||||----|-||-|||-------  1    [M]    COG2829 Outer membrane phospholipase A
--------------------||-----------||-------|||-|-||||-||----|||----  1    [S]    COG2832 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  1    [M]    COG2834 Outer membrane lipoprotein-sorting protein
--||------|||-------------||||------------|||||-||-|||||----||||--  1    [S]    COG2835 Uncharacterized conserved protein
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  1    [P]    COG2837 Predicted iron-dependent peroxidase
--------------------------|||-------------|||||-||||-|||---|||||--  1    [O]    COG2844 UTP:GlnB (protein PII) uridylyltransferase
------------------------------|---|-------|||||---|--|||----|-----  1    [D]    COG2846 Regulator of cell morphogenesis and NO signaling
--------------------|-||------------|--------||--|---||---|-------  1    [S]    COG2849 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--|||||||----------  1    [S]    COG2850 Uncharacterized conserved protein
--------------------|---------------------|||||-||||||||--|----|||  1    [M]    COG2853 Surface lipoprotein
------------------------------------------|||||-||||||||--|----|||  1    [Q]    COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1    [S]    COG2855 Predicted membrane protein
-------------------------|-----------|----|||-|--|||------|||-||--  1    [S]    COG2861 Uncharacterized protein conserved in bacteria
--|-------------|----|--------------------|||-||||||---|||||---|--  1    [S]    COG2862 Predicted membrane protein
--|----------||---|-----------------||----|||||--|---|||-------|--  1    [E]    COG2866 Predicted carboxypeptidase
-------------||---------------------------|||||-||-|||||---|||||||  1    [I]    COG2867 Oligoketide cyclase/lipid transport protein
-|--------------|---|---------------------||||||-|||-||||||---||--  1    [M]    COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2875 Precorrin-4 methylase
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
--|--------------|--|---------------------||||||||||||||----------  1    [C]    COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB
-----------------|------|-----|-----||----||||||||-----|----------  1    [N    U    O]    COG2882 Flagellar biosynthesis chaperone
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  1    [D]    COG2884 Predicted ATPase involved in cell division
-------------------|----|------|-|||||----|||||-|||||--|----------  1    [M]    COG2891 Cell shape-determining protein
----------------||||||--------|----|||----||||||||--||||||-||||---  1    [D]    COG2894 Septum formation inhibitor-activating ATPase
--------------------------|||-|-----------||||||||--||||---|||||--  1    [P]    COG2895 GTPases - Sulfate adenylate transferase subunit 1
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1    [H]    COG2896 Molybdenum cofactor biosynthesis enzyme
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  1    [P]    COG2897 Rhodanese-related sulfurtransferase
------------------------------------------|||||-|||||||----||||---  1    [S]    COG2900 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1    [K    L]    COG2901 Factor for inversion stimulation Fis, transcriptional activator
------------------------------------------|||||-|||||--|--------||  1    [S]    COG2904 Uncharacterized protein conserved in bacteria
------------------|---------|-------------||-||-||--||||-------|--  1    [P]    COG2906 Bacterioferritin-associated ferredoxin
-----------------|------------------------|||||-|||||||||||||-||--  1    [S]    COG2908 Uncharacterized protein conserved in bacteria
---------------------------||-|-----------|||||-||----------------  1    [K]    COG2909 ATP-dependent transcriptional regulator
------------------------------------------||||||||||||||---|||||--  1    [S]    COG2911 Uncharacterized protein conserved in bacteria
-------------------|--||------------------|||||||||||--|-------|--  1    [S]    COG2912 Uncharacterized conserved protein
------------------------------------------||||||||||||||---|||||||  1    [J]    COG2913 Small protein A (tmRNA-binding)
------------------------------------------||||||||||||||----------  1    [S]    COG2914 Uncharacterized protein conserved in bacteria
------------------------------------------|||||||||||-------------  1    [R]    COG2915 Uncharacterized protein involved in purine metabolism
------------------------------------------||||||||||-|||----||||||  1    [D]    COG2917 Intracellular septation protein A
------------------------------|----|------||||||||-|--------------  1    [H]    COG2918 Gamma-glutamylcysteine synthetase
------------------------||||||-|||||||----||||||||||||||---|||||||  1    [D]    COG2919 Septum formation initiator
--------|-|-------------------------------||||||||||--------------  1    [P]    COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit
------------------------------------------||||||||||||||----------  1    [S]    COG2921 Uncharacterized conserved protein
------------------------------------------|||||||---|||-----------  1    [S]    COG2922 Uncharacterized protein conserved in bacteria
|-|--------------|------------------------||||||||||--------------  1    [P]    COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur
------------------------------------------||||||||||||||----------  1    [C    O]    COG2924 Fe-S cluster protector protein
------------------------------------------|||||||||||--|----------  1    [L]    COG2925 Exonuclease I
--------------------|---------------------|||||||-||--------------  1    [S]    COG2926 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||||  1    [L]    COG2927 DNA polymerase III, chi subunit
------------------||--------------------------|-|---|||-----||-|--  1    [S]    COG2929 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--||||-------------  1    [R]    COG2933 Predicted SAM-dependent methyltransferase
---------------------------|||------------|||||-|||||-------------  1    [I]    COG2937 Glycerol-3-phosphate O-acyltransferase
-------------||---------------------------|||||-||||||||---|||||||  1    [S]    COG2938 Uncharacterized conserved protein
------------------||----------------------|||-|-----|--|---|||||--  1    [G]    COG2942 N-acyl-D-glucosamine 2-epimerase
------------------------------------------|||-|-||--|--|-------|--  1    [M]    COG2943 Membrane glycosyltransferase
--------------------------|||-------------|||||-||-|||||---|||||--  1    [M]    COG2951 Membrane-bound lytic murein transglycosylase B
------------------------------------------|||||-|-||||||----------  1    [G]    COG2956 Predicted N-acetylglucosaminyl transferase
------------------------------------------|||||-||||-|||----------  1    [H]    COG2959 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||--||||---||||---  1    [S]    COG2960 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||-|  1    [R]    COG2961 Protein involved in catabolism of external DNA
--------------------|-----------|---------|||||-||||---|--|-|-----  1    [S]    COG2964 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-|||----------  1    [L]    COG2965 Primosomal replication protein N
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1    [S]    COG2966 Uncharacterized conserved protein
---------------------|--------------------|||||-||--|--|---|||||--  1    [P]    COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport
--||--------------||-------||--------|----|||||-|---|------|||||--  1    [S]    COG2968 Uncharacterized conserved protein
------------------------------------------|||||-||||||||----------  1    [R]    COG2969 Stringent starvation protein B
----------------------|-------------------|||||-|-|||-------------  1    [K]    COG2973 Trp operon repressor
------------------------------------------|||||-||||||||----------  1    [L]    COG2974 DNA recombination-dependent growth factor C
------------------------------------------|||||-|||--|||----------  1    [S]    COG2975 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||----------  1    [S]    COG2976 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-||---------|-||---  1    [Q]    COG2977 Phosphopantetheinyl transferase component of siderophore synthetase
------------------------------------------|||-|-||-|-||----||||---  1    [S]    COG2979 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1    [M]    COG2980 Rare lipoprotein B
------------------|-----------------------|||||-||||-------||||---  1    [E]    COG2981 Uncharacterized protein involved in cysteine biosynthesis
-|----------------------------------------|||||-||||-------|||||--  1    [S]    COG2983 Uncharacterized conserved protein
---|||--------------||----------|-|-||-------||-||-----|---|||||--  1    [E]    COG2986 Histidine ammonia-lyase
------------------||----------------------|||||-||----------------  1    [E]    COG2988 Succinylglutamate desuccinylase
------------------------------------------|||||-|-||-------|||||--  1    [S]    COG2989 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||-|-|---------|-------  1    [R]    COG2992 Uncharacterized FlgJ-related protein
------------------------------------------|||-|-|--|-||-----------  1    [O]    COG2999 Glutaredoxin 2
------------------||------|-------|-------|||||-|--|--------------  1    [G]    COG3001 Fructosamine-3-kinase
------------------------------------------|||||-|-||----|||-||||-|  1    [P]    COG3004 Na+/H+ antiporter
------------------------------------------|||||-|-||--------------  1    [D]    COG3006 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-||---|||----------  1    [S]    COG3009 Uncharacterized protein conserved in bacteria
---------------------|----|---------------|||||-||||-|-|----------  1    [S]    COG3012 Uncharacterized protein conserved in bacteria
-|----------------------------------------|||||-|--|--------------  1    [S]    COG3013 Uncharacterized conserved protein
------------------------------------------|||||-||||||||----------  1    [M]    COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis
-------------------|-|--------------------|||||-|--|-------|-|||--  1    [S]    COG3021 Uncharacterized protein conserved in bacteria
----------------|---|-----|-----||--------|||||-||||-|||--|----|-|  1    [S]    COG3022 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----||||--  1    [S]    COG3024 Uncharacterized protein conserved in bacteria
--|---------------------------------------|||||-||||---|------||--  1    [S]    COG3025 Uncharacterized conserved protein
------------------------------------------|||||-||||---|----------  1    [T]    COG3026 Negative regulator of sigma E activity
-----------------------|------|---||||----|||||-|||||||----|||||||  1    [S]    COG3027 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||----------  1    [S]    COG3028 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-|-||--------------  1    [C]    COG3029 Fumarate reductase subunit C
--||----------------------||-------|||----|||||-||-|-||----||||---  1    [R]    COG3030 Protein affecting phage T7 exclusion by the F plasmid
------------------------------------------|--||-||||-|------------  1    [S]    COG3036 Uncharacterized protein conserved in bacteria
--------------------------|---------------|||-|-||--------||--||--  1    [M]    COG3040 Bacterial lipocalin
-------------------|-------------|--------|||-|-|-|-|---||-|------  1    [S]    COG3041 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||------|||-----  1    [C]    COG3043 Nitrate reductase cytochrome c-type subunit
------------------------------------------|||||-||---|||---||||---  1    [S]    COG3045 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-||--|---|-|||||  1    [M]    COG3047 Outer membrane protein W
--------------------|---------------||----|||-|-||----------------  1    [E]    COG3048 D-serine dehydratase
--|---------------|------------|--|-|---------|-|----------|-||---  1    [M]    COG3049 Penicillin V acylase and related amidases
------------------------------------------|||||-|-||--------------  1    [L]    COG3050 DNA polymerase III, psi subunit
------------------------------------------|||||-|-||--------------  1    [R]    COG3054 Predicted transcriptional regulator
--------------------|---------------------|||||-|-||---------|----  1    [S]    COG3055 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [M]    COG3056 Uncharacterized lipoprotein
------------------------------------------|||||-|-||--------------  1    [L]    COG3057 Negative regulator of replication initiationR
----------------|-------------------------|||||--|||--------|-----  1    [O]    COG3058 Uncharacterized protein involved in formate dehydrogenase formation
------------------------------------------|||-|-|-||----||--------  1    [S]    COG3059 Predicted membrane protein
------------------------------------------|||||-|-||--------------  1    [K    E]    COG3060 Transcriptional regulator of met regulon
------------------------------------------|||||-|-||--------------  1    [M]    COG3061 Cell envelope opacity-associated protein A
------------------------------------------|||||-||||------|||-----  1    [P]    COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase
------------------------------------------|||||-|-||--------------  1    [M]    COG3064 Membrane protein involved in colicin uptake
------------------------------------------|||||-|-|||-------------  1    [M]    COG3065 Starvation-inducible outer membrane lipoprotein
------------------------------------------|||||-|-||--------------  1    [L]    COG3066 DNA mismatch repair protein
------------------------------------------|||||-||||--------------  1    [P]    COG3067 Na+/H+ antiporter
------------------------------------------|||||-|-||--------------  1    [S]    COG3068 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|-|-||--------------  1    [C]    COG3069 C4-dicarboxylate transporter
------------------------------|--|||------|||||-||||-|-|----|-||-|  1    [K]    COG3070 Regulator of competence-specific genes
------------------------------------------|||||-||||||||----------  1    [H]    COG3071 Uncharacterized enzyme of heme biosynthesis
------------------------------------------|||||-||||--------------  1    [F]    COG3072 Adenylate cyclase
------------------------------------------|||||-|||||--|----------  1    [T]    COG3073 Negative regulator of sigma E activity
------------------------------------------|||||-|-||--------------  1    [S]    COG3074 Uncharacterized protein conserved in bacteria
---|--------------------------------------|||||-|-||--------------  1    [E]    COG3075 Anaerobic glycerol-3-phosphate dehydrogenase
------------------------------------------|||||-|-||--------------  1    [S]    COG3076 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3078 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|||||-------------  1    [S]    COG3079 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-|-||--------------  1    [C]    COG3080 Fumarate reductase subunit D
------------------------------------------|||||-||||--------------  1    [R]    COG3081 Nucleoid-associated protein
------------------------------------------|||||-|-||--------------  1    [S]    COG3082 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1    [R]    COG3083 Predicted hydrolase of alkaline phosphatase superfamily
------------------------------------------|||||-|-||--------------  1    [S]    COG3084 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3085 Uncharacterized protein conserved in bacteria
-----------------|--|---------------------|||||-||||--------------  1    [T]    COG3086 Positive regulator of sigma E activity
------------------------------------------|||||-||||||||----------  1    [D]    COG3087 Cell division protein
------------------------------------------|||||-||||--------------  1    [S]    COG3089 Uncharacterized protein conserved in bacteria
-------------------------------|||||||----|||||-||||--------------  1    [S]    COG3091 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3092 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-||-----------  1    [S]    COG3094 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [D]    COG3095 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-|-||--------------  1    [D]    COG3096 Uncharacterized protein involved in chromosome partitioning
------------------------------------------|||||-|-||--------------  1    [S]    COG3097 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1    [S]    COG3098 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3099 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1    [S]    COG3100 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3101 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3102 Uncharacterized protein conserved in bacteria
-----------------------------------||-----|||||-||||--------------  1    [T]    COG3103 SH3 domain protein
------------------------------------------|||||-||||--------------  1    [S]    COG3105 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-------||||---  1    [R]    COG3106 Predicted ATPase
------------------------------------------|||||-|||||-------------  1    [R]    COG3107 Putative lipoprotein
------------------------------------------|||||-|-||-------|||||--  1    [S]    COG3108 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||--------------  1    [T]    COG3109 Activator of osmoprotectant transporter ProP
------------------------------------------|||||-|-||--------------  1    [S]    COG3110 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3112 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||||||----------  1    [R]    COG3113 Predicted NTP binding protein (contains STAS domain)
------------------------------------------|||||-|||||-------------  1    [D]    COG3115 Cell division protein
------------------------------------------|||||||||||--|----------  1    [D]    COG3116 Cell division protein
------------------------------------------|||||-||||||||----------  1    [S]    COG3117 Uncharacterized protein conserved in bacteria
--------------------------||||------------|||||-|||||--|---|||||--  1    [O]    COG3118 Thioredoxin domain-containing protein
------------------------------------------|||||-|-||--------------  1    [S]    COG3120 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|--|-------------  1    [S]    COG3122 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|----------  1    [S]    COG3123 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1    [S]    COG3124 Uncharacterized protein conserved in bacteria
----------------------------------||||----||||||-|--|--|---|-|||--  1    [C]    COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
------------------------------------------|||||-||---------|-||---  1    [S]    COG3126 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||||--  1    [Q]    COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
--------------|---------------------------|||||-||----------------  1    [R]    COG3129 Predicted SAM-dependent methyltransferase
------------------------------------------|||||-||----------------  1    [J]    COG3130 Ribosome modulation factor
------------------------------------------|||||-||------------|---  1    [S]    COG3132 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|||---|----------  1    [M]    COG3133 Outer membrane lipoprotein
------------------------------------------|||||--|--|-------------  1    [S]    COG3134 Predicted outer membrane lipoprotein
---------------------|----|---------------|||-|-||----------|||---  1    [Q]    COG3135 Uncharacterized protein involved in benzoate metabolism
------------------------------------------|||||-||------------|---  1    [R]    COG3136 Uncharacterized membrane protein required for alginate biosynthesis
------------------------------------------|||||-|---|-------------  1    [M]    COG3137 Putative salt-induced outer membrane protein
------------------------------------------|||||-||-------------|--  1    [E]    COG3138 Arginine/ornithine N-succinyltransferase beta subunit
------------------------------------------|||||-||----------------  1    [S]    COG3139 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [S]    COG3140 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1    [S]    COG3141 Uncharacterized protein conserved in bacteria
--------------------|----------|||-|------|||||-|--||------||-||--  1    [P]    COG3142 Uncharacterized protein involved in copper resistance
------------------------------------------|||||-||-----|----------  1    [N    T]    COG3143 Chemotaxis protein
-----------------|------------|-----||----||||||||-----|----------  1    [N]    COG3144 Flagellar hook-length control protein
--------------|----|------||||------------|||-|-||--|--|---|||||--  1    [L]    COG3145 Alkylated DNA repair protein
------------------------------------------|||||-||--|--|----------  1    [S]    COG3147 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1    [S]    COG3148 Uncharacterized conserved protein
------------------------------------------|||||-||--|-------------  1    [S]    COG3151 Uncharacterized protein conserved in bacteria
--|----------------|------|----|--||------|||||-||---------|||||--  1    [R]    COG3153 Predicted acetyltransferase
------------------------------------------|||||-||-----|---|||----  1    [I]    COG3154 Putative lipid carrier protein
------------------------------------------|||||-||----------------  1    [Q]    COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis
--|-----------------------|----||---------|||||-||--|--|---|||||--  1    [P]    COG3158 K+ transporter
------------------------------------------|||||-||-||--|-------|--  1    [S]    COG3159 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1    [K]    COG3160 Regulator of sigma D
|||-----||-----------------|||------------|||||-||-|-|||----------  1    [H]    COG3161 4-hydroxybenzoate synthetase (chorismate lyase)
---------------------|----|---------|-----|||||--|--|-------------  1    [S]    COG3162 Predicted membrane protein
------------------------------------------|||||-||--|--|----------  1    [S]    COG3164 Predicted membrane protein
------------------------------------------|||||-||-|||||----------  1    [S]    COG3165 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||-||--||||------|---  1    [N    U]    COG3166 Tfp pilus assembly protein PilN
------------------------------------------|||||--|||-||-----------  1    [S]    COG3171 Uncharacterized protein conserved in bacteria
---------------------------||--|----------|||||--|||--------------  1    [H]    COG3172 Predicted ATPase/kinase involved in NAD metabolism
-------------------||-----|-------|-||----|||-|-||---------||-|---  1    [R]    COG3180 Putative ammonia monooxygenase
--------------------|-----|---------||--------|-||-|---|---||-----  1    [S]    COG3181 Uncharacterized protein conserved in bacteria
--|------------------|------------------------|-||------------|---  1    [V]    COG3183 Predicted restriction endonuclease
--|---------------|-||----|---------------|||||-||-----||||||||---  1    [O]    COG3187 Heat shock protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1    [S]    COG3189 Uncharacterized conserved protein
----------------------||------------||----||||||||-----|----------  1    [N]    COG3190 Flagellar biogenesis protein
--------------------|--------------||-----|||-|--|----------------  1    [E]    COG3192 Ethanolamine utilization protein
----------||------|----------------|------|---|--|-----|---|-|||--  1    [R]    COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
-------------||---------------------------|||-|--|---------||||---  1    [F]    COG3194 Ureidoglycolate hydrolase
----------------||||----------------------|||-|-||-||--|---|||||--  1    [M]    COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis
---------------------|-----||-------------|||-|--|---------||-||--  1    [S]    COG3214 Uncharacterized protein conserved in bacteria
---|---------------|----------------------|||||-||---------||-||--  1    [R]    COG3217 Uncharacterized Fe-S protein
-------------------------------|---||-----|||||--||---------------  1    [S]    COG3223 Predicted membrane protein
---------------------------||-------------|||-|--|----------------  1    [S]    COG3226 Uncharacterized protein conserved in bacteria
------------------||----------------------|||||--|-----|----------  1    [S]    COG3228 Uncharacterized protein conserved in bacteria
---------------------|-----------------------||-||-|---|-----|----  1    [E]    COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
-------------------|------|----||||||-----|||-|--|---------||-||--  1    [S]    COG3237 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||--|--|-----||---  1    [S]    COG3242 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|-||----------------  1    [M]    COG3248 Nucleoside-binding outer membrane protein
---------------------------||-------|------|--|--|-----|---|------  1    [S]    COG3251 Uncharacterized protein conserved in bacteria
----||-----------------------------|||----|||||-----------|||||---  1    [S]    COG3254 Uncharacterized conserved protein
---------------------|--------------------|||-|--|---------||||---  1    [R]    COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization
|||--|||-|-|---------------||-------------|||-|-------------------  1    [C]    COG3260 Ni,Fe-hydrogenase III small subunit
|||--|||-|-|---------------|--------------|||-|-------------------  1    [C]    COG3261 Ni,Fe-hydrogenase III large subunit
--|---||-------------------|--------------|||-|-------------------  1    [C]    COG3262 Ni,Fe-hydrogenase III component G
--------------------|----------------|----|||-|-||---------|--|---  1    [P]    COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
------------------------------------------|||||-||----------------  1    [S]    COG3266 Uncharacterized protein conserved in bacteria
---------------------------||-----------------|-||----------------  1    [U]    COG3267 Type II secretory pathway, component ExeA (predicted ATPase)
------|||-----------------------||--------|||-|-|-----------------  1    [S]    COG3270 Uncharacterized conserved protein
|-|---------------------------------------|||||-||----------------  1    [S]    COG3272 Uncharacterized conserved protein
-------------------------------|----------|||||-|------|--------|-  1    [S]    COG3274 Uncharacterized protein conserved in bacteria
--------------------|-------------|-|-----|||||-|-----------|-----  1    [T]    COG3275 Putative regulator of cell autolysis
-||-||---|-|----|-------------------------|||-|--|||------|-|-----  1    [J]    COG3276 Selenocysteine-specific translation elongation factor
--------------------|---------||||||||----|||||-||--|--|---|||||--  1    [K    T]    COG3279 Response regulator of the LytR/AlgR family
-----------|-------|-|----|||-----------------|--|-----|----|-----  1    [G]    COG3280 Maltooligosyl trehalose synthase
------------------------------------------|||||-||||--------------  1    [K    E]    COG3283 Transcriptional regulator of aromatic amino acids metabolism
------------------||-------|-|------------|||||-||||-|||---|||||||  1    [C]    COG3288 NAD/NADP transhydrogenase alpha subunit
------------------|-----------------|---------|--|-----|---||-||--  1    [T]    COG3300 MHYT domain (predicted integral membrane sensor domain)
--------|-||------------------------------|||-|---||--------------  1    [P]    COG3301 Formate-dependent nitrite reductase, membrane component
------------------------------------------|||-|---||------|-------  1    [P]    COG3303 Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit
--------------------------|||-------------|||||-|--|-----------|--  1    [S]    COG3304 Predicted membrane protein
-----------------||||---------|--||-------|||||-||||||||||-|||||||  1    [M]    COG3307 Lipid A core - O-antigen ligase and related enzymes
------------------------------------------|||||-|---|--|----|||---  1    [K]    COG3311 Predicted transcriptional regulator
------------------------------------------|||||-||||-||-----------  1    [C]    COG3312 F0F1-type ATP synthase, subunit I
------------------------------------------|||||-||-----|----||||--  1    [R]    COG3313 Predicted Fe-S protein
--------------------|---------|---|-||----|||-|-|-----------|-----  1    [S]    COG3314 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-|||----------  1    [M]    COG3317 Uncharacterized lipoprotein
----------------------||------------|-----|||-|-||---||-----------  1    [R]    COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA
-------------------|------||||------|-----|||||--|-----|-----||---  1    [Q]    COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
--|-----------------------|||--------|--------|-||-|---|---|||||--  1    [R]    COG3324 Predicted enzyme related to lactoylglutathione lyase
---|---------|---------------------|-|--------|-|-----------------  1    [G]    COG3325 Chitinase
--|----------------------------|||-|||--------|--|---||-|--|------  1    [S]    COG3326 Predicted membrane protein
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  1    [L]    COG3328 Transposase and inactivated derivatives
--------------------|-----|----------|--------|-||-|---|---||-----  1    [S]    COG3333 Uncharacterized protein conserved in bacteria
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|---  1    [L]    COG3335 Transposase and inactivated derivatives
-------------------|||----|--------|||----|||-|---||--------------  1    [E]    COG3340 Peptidase E
--|----------|----|||------||-|---|--|----|--||-||----------|-----  1    [L]    COG3344 Retron-type reverse transcriptase
----|------|--|------------||-----|----------||--------|||--------  1    [P]    COG3376 High-affinity nickel permease
---------||||-----------------|||---||--------|--|-----|------|---  1    [S]    COG3382 Uncharacterized conserved protein
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  1    [G]    COG3386 Gluconolactonase
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  1    [S]    COG3391 Uncharacterized conserved protein
-----------------------------------|-|----|||||-|------------||---  1    [S]    COG3394 Uncharacterized protein conserved in bacteria
----------------|--------------------|----|||-|------------|------  1    [G]    COG3405 Endoglucanase Y
------------------------------------------|||||||-------|||-------  1    [R]    COG3417 Collagen-binding surface adhesin SpaP (antigen I/II family)
------------------------------------------||||||||----------------  1    [N    U    O]    COG3418 Flagellar biosynthesis/type III secretory pathway chaperone
---------------------------||-------|-----|||||-||-----------|----  1    [Q]    COG3433 Aryl carrier domain
-----------|--------------|----------|-----||-|--|-----|----------  1    [Q]    COG3435 Gentisate 1,2-dioxygenase
--||||-----|----|-------|---------------------|------||------|----  1    [S]    COG3439 Uncharacterized conserved protein
-------------------------------||||-|-----|||-|------------|--|---  1    [R]    COG3443 Predicted periplasmic or secreted protein
------------------------------------------|||||-|-||--------------  1    [R]    COG3445 Acid-induced glycyl radical enzyme
------------------||----------------------|||-|--|----------|-|---  1    [T]    COG3447 Predicted integral membrane sensor domain
-----------------|-|--------------------------|--|---------||-|---  1    [R]    COG3450 Predicted enzyme of the cupin superfamily
---|--------------------------|--------|------|-----|--|||-|||||||  1    [U]    COG3451 Type IV secretory pathway, VirB4 components
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3455 Uncharacterized protein conserved in bacteria
-----------------|----------------|--|----|---|---------------|---  1    [E]    COG3457 Predicted amino acid racemase
|-|||--------------|||--------||-----|--------|------|||----|||---  1    [R]    COG3467 Predicted flavin-nucleotide-binding protein
--------------------|----------||---||--------|-|-----------------  1    [C]    COG3493 Na+/citrate symporter
-------------------------------------------||-|--|--|--|---|------  1    [R]    COG3499 Phage protein U
-------------------|-----------------------||||-||-----|---|--|---  1    [S]    COG3501 Uncharacterized protein conserved in bacteria
-------------------|----------|---------------|-----|--|||-||-|-||  1    [U]    COG3505 Type IV secretory pathway, VirD4 components
---------------------------------------------||-----|||----||-|---  1    [S]    COG3514 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3515 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3516 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3517 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3518 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3519 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3520 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|------|---  1    [S]    COG3521 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3522 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  1    [S]    COG3523 Uncharacterized protein conserved in bacteria
-------------------------------------------||-|-|-------||--------  1    [S]    COG3528 Uncharacterized protein conserved in bacteria
-------------------------------------------|-||-||----------------  1    [R]    COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain
-------------------------------------------|-||-||-----|----------  1    [S]    COG3530 Uncharacterized protein conserved in bacteria
-----------------|-------------------|-----||-|------------||-||--  1    [S]    COG3533 Uncharacterized protein conserved in bacteria
----------|--------|----------|-----||-----||-|--|----------------  1    [P]    COG3546 Mn-containing catalase
-------------------|--------------------------|--|--|--|-----||---  1    [O]    COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
--------------------------------||-|------|||-|--|--|--|---|||||--  1    [R]    COG3568 Metal-dependent hydrolase
--------------------|-------------------------|----|-||-||--------  1    [V]    COG3587 Restriction endonuclease
---------------------------------||-|-----|||||-------------|-|---  1    [E]    COG3591 V8-like Glu-specific endopeptidase
-||---------------|-|---------------------|||||-||-|-------|--|---  1    [L]    COG3593 Predicted ATP-dependent endonuclease of the OLD family
------------------------------------------|||||-||---------|||||--  1    [T]    COG3605 Signal transduction protein containing GAF and PtsI domains
-||||||||-|||------|-------||--------------||||-----|--|---||-||--  1    [K]    COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
|------------||-----|-----|||-|--|||-|----|||||-|-|||-----|-------  1    [S]    COG3610 Uncharacterized conserved protein
--------------------------------|---------|||||-||||-||---|-------  1    [E]    COG3633 Na+/serine symporter
-------------------------------||-|-|-----|||-|--|--|--|-------|--  1    [O]    COG3634 Alkyl hydroperoxide reductase, large subunit
-------------------|-------------|-----|-----||-||---|-------|-|--  1    [R]    COG3654 Prophage maintenance system killer protein
--|-----------|------|--------------------|||-|----|-|||--|----|--  1    [L]    COG3663 G:T/U mismatch-specific DNA glycosylase
--||--||---|------|-----------|-----------|||||--------|----------  1    [L]    COG3677 Transposase and inactivated derivatives
-|------------------|---------------------|||-|---|---------------  1    [S]    COG3681 Uncharacterized conserved protein
--------------------|---|--------------------||---||-------||||---  1    [R]    COG3683 ABC-type uncharacterized transport system, periplasmic component
--------------------------------||||------|||-|---------------|---  1    [G]    COG3684 Tagatose-1,6-bisphosphate aldolase
------------------------------------------|||||-|-||--------------  1    [S]    COG3691 Uncharacterized protein conserved in bacteria
--------------|------|----|||--|---|------|||||-||----------------  1    [L]    COG3695 Predicted methylated DNA-protein cysteine methyltransferase
----------------|-||----------------------|||-|--|-----|||--|--|--  1    [P]    COG3696 Putative silver efflux pump
--------------------------------|---------|||-|---|---------------  1    [R]    COG3700 Acid phosphatase (class B)
--------------------|---------------------|||||-|--|---|---||-||--  1    [M]    COG3713 Outer membrane protein V
---------------------------||-------------|||||-|------|-----|||--  1    [S]    COG3714 Predicted membrane protein
------------------------------------||----|||||------------||--|--  1    [G]    COG3717 5-keto 4-deoxyuronate isomerase
--------------------------|--------|||-------||--------|---|||||--  1    [G]    COG3718 Uncharacterized enzyme involved in inositol metabolism
------------------------------------------|||-|---||-------|||||--  1    [J]    COG3719 Ribonuclease I
------------------------------------------|||||-|--|--------------  1    [K]    COG3722 Transcriptional regulator
------------------------------------------|||||--|-------------|--  1    [E]    COG3724 Succinylarginine dihydrolase
------------------------------------------|||||--|--|-------------  1    [V]    COG3725 Membrane protein required for beta-lactamase induction
------------------------------------------|||||-||-|--------------  1    [R]    COG3726 Uncharacterized membrane protein affecting hemolysin expression
------------------------------------------|||-|-------||----|--|--  1    [L]    COG3727 DNA G:T-mismatch repair endonuclease
------------------------------------------|---|--------|---|||||--  1    [G]    COG3734 2-keto-3-deoxy-galactonokinase
------------------------|-----|-----------|||||-|----------|||||--  1    [S]    COG3735 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--|-|-----------|--  1    [S]    COG3738 Uncharacterized protein conserved in bacteria
---------------------------||--|---|-------||-|--------|---|---|--  1    [R]    COG3740 Phage head maturation protease
-------------------|-|--------------------|||-|--|---------||-||--  1    [S]    COG3755 Uncharacterized protein conserved in bacteria
------------------------------------||----|||-|--------|---|---|--  1    [S]    COG3766 Predicted membrane protein
------------------------------------------|||||---||-------||||---  1    [S]    COG3768 Predicted membrane protein
------||----|-----------------------------|||-|-------------------  1    [R]    COG3769 Predicted hydrolase (HAD superfamily)
------------------------------------------|||||---||-------||||---  1    [M]    COG3770 Murein endopeptidase
------------------------------------------|||||-|-||--------------  1    [S]    COG3771 Predicted membrane protein
------------------------------------------|||||-||----------------  1    [S]    COG3776 Predicted membrane protein
------------------||----------------------|||-|--------|------|---  1    [S]    COG3781 Predicted membrane protein
------------------------------------------|||||-|--|--------------  1    [C]    COG3783 Soluble cytochrome b562
------------------------------------------|||||--|-------------|--  1    [S]    COG3784 Uncharacterized protein conserved in bacteria
------------------------------------------|||||------------|||||--  1    [S]    COG3785 Uncharacterized conserved protein
------------------------------------------|||||----|------|-------  1    [S]    COG3787 Uncharacterized protein conserved in bacteria
-------------------|----------------------|||||-|--------------|--  1    [R]    COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily
------------------------------------------|||-|--|-------------|--  1    [S]    COG3789 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|--|--------------  1    [S]    COG3790 Predicted membrane protein
----------------------------------------------|--|----------|-||--  1    [S]    COG3811 Uncharacterized protein conserved in bacteria
----|--|--||-----|---|---------|||||||-|--|||||-|-----------------  1    [G]    COG3833 ABC-type maltose transport systems, permease component
------------------------------|-----||----|||||-|||---------------  1    [K    T]    COG3835 Sugar diacid utilization regulator
------------------------------------------|||||-|-||-------||||---  1    [H]    COG3840 ABC-type thiamine transport system, ATPase component
------------------------------------------|||-|-|--|--------------  1    [T]    COG3851 Signal transduction histidine kinase, glucose-6-phosphate specific
------------------------------------------|||||-||--|--|---|||||--  1    [T]    COG3852 Signal transduction histidine kinase, nitrogen specific
---------------------------------------------||--------|---|||||--  1    [S]    COG3892 Uncharacterized protein conserved in bacteria
------------------|-----------------------|||||--|-----|---|||----  1    [R]    COG3895 Predicted periplasmic protein
----------------------------------------------|--|---------||||---  1    [S]    COG3921 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||--------------  1    [L]    COG3923 Primosomal replication protein N''
------------------------------------------|||||---||--------------  1    [S]    COG3924 Predicted membrane protein
------------------------------------------|||||---||--------------  1    [G]    COG3925 N-terminal domain of the phosphotransferase system fructose-specific component IIB
----------------------------------------------|------||-----|||---  1    [R]    COG3926 Putative secretion activating protein
------------------------------|------|--------|-------------------  1    [R]    COG3940 Predicted beta-xylosidase
---------------------------------------------||--|---||-----------  1    [R]    COG3943 Virulence protein
------------------------|-----------------||||||||-----|----------  1    [M    N    O]    COG3951 Rod binding protein
------------------------------------------|||||-|-----------|-----  1    [C]    COG3954 Phosphoribulokinase
-|--||-|--|||----|--|------------|-----------||------------||-|---  1    [G]    COG3958 Transketolase, C-terminal subunit
-|--||-|--|||----|--|------------|-----------||------------||-|---  1    [G]    COG3959 Transketolase, N-terminal subunit
------------------------------------------|||-|--|-----|----|-|---  1    [R]    COG3960 Glyoxylate carboligase
--|----------||------------|||||--|-----------|-------------------  1    [G    H    R]    COG3961 Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes
-------------------------------||--|------|||-|--|-----|----------  1    [R]    COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase
---------------------|-----||-------------|||||--|-|---|---|-|-|--  1    [Q]    COG3971 2-keto-4-pentenoate hydratase
----------------------------------------------|--|--|------|------  1    [R]    COG3972 Superfamily I DNA and RNA helicases
-------------------|----------------------|||||-|----||-----------  1    [E]    COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase
------------------------------------------|||||-|--||-------------  1    [S]    COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit
--|----------------|-------------|--------|||-|--------|----------  1    [V]    COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
----------------|-------------------------||||||||||||||||||||||||  1    [R]    COG4105 DNA uptake lipoprotein
------------------||-|----|---||||||------||||||||||||||---|||||--  1    [J]    COG4108 Peptide chain release factor RF-3
-------------------------------------|----|||||-------------|-----  1    [R]    COG4114 Uncharacterized Fe-S protein
-------------------|----------------------|||-|--|-----|-----||---  1    [C]    COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
||--------------|-||-|---|----------------|||||-||||---|--|||--|--  1    [S]    COG4121 Uncharacterized conserved protein
----------------||--|---------||||||||||--|||||-|-||----||||||||--  1    [R]    COG4123 Predicted O-methyltransferase
---------------------------------------------||--|-----|---||-----  1    [S]    COG4125 Predicted membrane protein
--|---------------------------|---------------|----------------|--  1    [S]    COG4127 Uncharacterized conserved protein
----------------------------------------------|--------|---||-|---  1    [G]    COG4130 Predicted sugar epimerase
------------------------------------------|||||-||-|||||----------  1    [R]    COG4137 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-|-----------------  1    [H]    COG4138 ABC-type cobalamin transport system, ATPase component
------------------------------------------|||||-|-----------------  1    [H]    COG4139 ABC-type cobalamin transport system, permease component
---|--||--|----------|--|-----------------|||||-|-||-||----||||---  1    [H]    COG4143 ABC-type thiamine transport system, periplasmic component
--------|-----------|----|----------------|||||---||--------------  1    [H]    COG4145 Na+/panthothenate symporter
--------|-------|--|-|----|---------||----|||||-||--|--|----------  1    [R]    COG4147 Predicted symporter
----------------------------------|-------|||||-||||-------||||---  1    [P]    COG4148 ABC-type molybdate transport system, ATPase component
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1    [P]    COG4149 ABC-type molybdate transport system, permease component
------------------------------------------|||||-|----------|-||---  1    [P]    COG4150 ABC-type sulfate transport system, periplasmic component
---------------------------------|--------|||-|---|--------||||---  1    [G]    COG4154 Fucose dissimilation pathway protein FucU
------------------------------------------|||||-|-||--------------  1    [E]    COG4161 ABC-type arginine transport system, ATPase component
------------------------------------------|||||-|-||--------------  1    [V]    COG4167 ABC-type antimicrobial peptide transport system, ATPase component
------------------------------------------|||||-|-||--------------  1    [V]    COG4168 ABC-type antimicrobial peptide transport system, permease component
------------------------------------------|||||-|-||--------------  1    [V]    COG4170 ABC-type antimicrobial peptide transport system, ATPase component
------------------------------------------|||||-|-||--------------  1    [V]    COG4171 ABC-type antimicrobial peptide transport system, permease component
--------------------|---------------------|||||-||-----|---||||---  1    [R]    COG4172 ABC-type uncharacterized transport system, duplicated ATPase component
------------------------------------------|||||-||-----|||-||||---  1    [R]    COG4174 ABC-type uncharacterized transport system, permease component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1    [E]    COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  1    [E]    COG4176 ABC-type proline/glycine betaine transport system, permease component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  1    [E]    COG4177 ABC-type branched-chain amino acid transport system, permease component
------------------------------------------|||||-||-----|---||-||--  1    [Q]    COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
----------------------------------------------|-|--|--------------  1    [T]    COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system
------------------------------------------|||||-||-----|-----|-|--  1    [H]    COG4206 Outer membrane cobalamin receptor protein
------------------||-------||--------|----|||||-||--||||---|||||--  1    [P]    COG4208 ABC-type sulfate transport system, permease component
--------------------|---|-----------------|||||-|-||--------------  1    [G]    COG4211 ABC-type glucose/galactose transport system, permease component
------------------------------------------|||-|-----|------|------  1    [L]    COG4220 Phage DNA packaging protein, Nu1 subunit of terminase
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1    [R]    COG4221 Short-chain alcohol dehydrogenase of unknown specificity
------------------------------|-----||-------||------------|------  1    [R]    COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
------------------------------------------|||||--|-|-|||---|||||--  1    [C]    COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
----------------------||----------------------|------------|||||--  1    [O    C]    COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis
-------------------------|----------------|||||-||-----|||-||||---  1    [R]    COG4239 ABC-type uncharacterized transport system, permease component
------------------------------------------|||-|--------|----|-|---  1    [P]    COG4256 Hemin uptake protein
---------------------|--------------------|||||--------|---||-----  1    [S]    COG4269 Predicted membrane protein
-----------------|----------------------------|-----|--|----------  1    [R]    COG4287 PhoPQ-activated pathogenicity-related protein
--------------------|---------|----|------|||-|--|-----|----------  1    [E]    COG4302 Ethanolamine ammonia-lyase, small subunit
--------------------|---------|----|------|||-|--|-----|----------  1    [E]    COG4303 Ethanolamine ammonia-lyase, large subunit
------------------------------|---------------|------------|--|---  1    [S]    COG4332 Uncharacterized protein conserved in bacteria
------------------------------||-|-|||-----|-||-------------------  1    [S]    COG4405 Uncharacterized protein conserved in bacteria
--------------------------|------|------------|-|--|--------------  1    [G]    COG4409 Neuraminidase (sialidase)
-------------------|--------------------------|-||----------------  1    [F    J]    COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA
--------------------|---------------------|||||--|---------|------  1    [V]    COG4452 Inner membrane protein involved in colicin E2 resistance
---------------------------------------------||--|---------|------  1    [R]    COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion
---------------------------------------------||----|----------|---  1    [S]    COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor
---------------------------------------------||----|----------|---  1    [S]    COG4458 Uncharacterized protein conserved in bacteria, putative virulence factor
----------------------------------------------|--|------------|---  1    [S]    COG4460 Uncharacterized protein conserved in bacteria
---------------------------||----------------||--|---------|--|---  1    [S]    COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein
------------------------------------------|||||-||||-------|||----  1    [P]    COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin
------------------------------------------||||||||||||||----------  1    [P]    COG4535 Putative Mg2+ and Co2+ transporter CorC
----------------------------------|-------|||||-||||---|----||||||  1    [P]    COG4536 Putative Mg2+ and Co2+ transporter CorB
------------------------------|----|----------|---------------|---  1    [Q]    COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
----------------------------------------------|--|-|---|---|||||--  1    [T]    COG4566 Response regulator
------------------------------------------|||||-||----------------  1    [K]    COG4568 Transcriptional antiterminator
------------------------------------------|||||------------|--|---  1    [M]    COG4571 Outer membrane protease
-------------------|----------------------|||-|------------------|  1    [R]    COG4572 Putative cation transport regulator
------------------------------------------|||||--------|---||-|---  1    [G]    COG4573 Predicted tagatose 6-phosphate kinase
------------------------------------------|||||--|---------------|  1    [R]    COG4574 Serine protease inhibitor ecotin
--------------------------||||-------|----|||-|----|----------|---  1    [K]    COG4578 Glucitol operon activator
------------------------------------------|||||--|-----|----------  1    [T]    COG4579 Isocitrate dehydrogenase kinase/phosphatase
------------------------------------------|||||-|------|----------  1    [G]    COG4580 Maltoporin (phage lambda and maltose receptor)
------------------------------------------|||||-|------|----------  1    [S]    COG4582 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||----------------  1    [P]    COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component
------------------------------------------|||||-||---------||-|---  1    [E]    COG4598 ABC-type histidine transport system, ATPase component
------------------------------------------|||-|--|-----|--|-------  1    [Q    P]    COG4615 ABC-type siderophore export system, fused ATPase and permease components
----------------------------------|-------|||-|--------|----------  1    [R]    COG4619 ABC-type uncharacterized transport system, ATPase component
------------------------------------------|||||-||||--------------  1    [M]    COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
--|----------------------------|----------|||||-|--|----------|---  1    [C    H]    COG4635 Flavodoxin
-------------------------------------------||||-----|--|----------  1    [S]    COG4643 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--|-----|----------  1    [K    T]    COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
------------------------------------------|||||-||--|--|----|||---  1    [P]    COG4651 Kef-type K+ transport system, predicted NAD-binding component
--|--------------|--|---------------------||||||||||--------------  1    [C]    COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA
--|--------------|--|---|-----------------||||||||||--------------  1    [C]    COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD
--|--------------|--|---------------------||||||||||--------------  1    [C]    COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG
--|--------------|--|---------------------||||||||||--------------  1    [C]    COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE
--------------------|-----|---|-----------|||||-|--|--------------  1    [R]    COG4667 Predicted esterase of the alpha-beta hydrolase superfamily
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1    [I]    COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
------------------------------|-----------|||||--------|----------  1    [G]    COG4677 Pectin methylesterase
-------------------|-------------|---------||||---|-|-------------  1    [S]    COG4679 Phage-related protein
-------------------|----------------------|||-|-------------|-|---  1    [S]    COG4680 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-----|----------  1    [S]    COG4681 Uncharacterized protein conserved in bacteria
------------------------------------|-----|||||--------|----------  1    [S]    COG4682 Predicted membrane protein
--|----------------------------||-------------|--|----------------  1    [E]    COG4690 Dipeptidase
----------------------------------------------|---------||-||-----  1    [G]    COG4692 Predicted neuraminidase (sialidase)
----------------------------------------------|----|---|----------  1    [S]    COG4714 Uncharacterized membrane-anchored protein conserved in bacteria
----------------------------------------------|-----|--|----------  1    [S]    COG4727 Uncharacterized protein conserved in bacteria
------------------||----------------------|||-|---------||--------  1    [S]    COG4735 Uncharacterized protein conserved in bacteria
-------------------|-----------------------||-|------|||----|-----  1    [S]    COG4737 Uncharacterized protein conserved in bacteria
--------------------|--------------|------|||-|------------|------  1    [E]    COG4766 Ethanolamine utilization protein
------------------------------------------|||||--|---||-----------  1    [P]    COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
-------------||-||||||||||----------------||||||||||||||||||||||||  1    [M]    COG4775 Outer membrane protein/protective antigen OMA87
------------------------------------------|||||||-||--------------  1    [K]    COG4776 Exoribonuclease II
--------------------------|---------------|||||-||---------|------  1    [P]    COG4779 ABC-type enterobactin transport system, permease component
----------------|-||----------------------|||||-||--|--|-----|||--  1    [R]    COG4783 Putative Zn-dependent protease, contains TPR repeats
------------------------------------------|||||-|-||--------------  1    [R]    COG4785 Lipoprotein NlpI, contains TPR repeats
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG4786 Flagellar basal body rod protein
------------------------------------------||||||||-----|----------  1    [N]    COG4787 Flagellar basal body rod protein
-------------------------------------------||||--|------------|---  1    [U]    COG4792 Type III secretory pathway, component EscU
------------------------------------------|||||-|||||--|-------|--  1    [U]    COG4795 Type II secretory pathway, component PulJ
----------------||||----------------------|||||-||||||||----------  1    [U]    COG4796 Type II secretory pathway, component HofQ
--|-----------------|---------------------|||-|--------|---------|  1    [S]    COG4804 Uncharacterized conserved protein
-----------------------------------|||----|||||-------------------  1    [G]    COG4806 L-rhamnose isomerase
--------------------|---------------------|||||--|----------------  1    [S]    COG4807 Uncharacterized protein conserved in bacteria
-----------------------------------|------|||||----|--------------  1    [S]    COG4811 Predicted membrane protein
--------------------|--------------|------|||-|-------------------  1    [E]    COG4812 Ethanolamine utilization cobalamin adenosyltransferase
--------------------|--------------|------|||-|-------------------  1    [E]    COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition
--------------------|--------------|------|||-|-------------------  1    [E]    COG4820 Ethanolamine utilization protein, possible chaperonin
--------------------|---------|----|----------|-------------------  1    [H]    COG4822 Cobalamin biosynthesis protein CbiK, Co2+ chelatase
-----------------|-----------------|----------|-------------------  1    [Q]    COG4869 Propanediol utilization protein
----------------------------------------------|-|------------|----  1    [S]    COG4890 Predicted outer membrane lipoprotein
----------------------------------------------|--|-----------|----  1    [S]    COG4893 Uncharacterized protein conserved in bacteria
-----------------------------------|----------|---------------|---  1    [Q]    COG4909 Propanediol dehydratase, large subunit
-----------------------------------|----------|---------------|---  1    [Q]    COG4910 Propanediol dehydratase, small subunit
-|---------------|-|-|----|-------------------|------------|------  1    [R]    COG4928 Predicted P-loop ATPase
--|-------|-----------------------------------|-------------------  1    [O]    COG4930 Predicted ATP-dependent Lon-type protease
------------------------------|----|----------|-------------------  1    [T    K]    COG4936 Predicted sensor domain
--------------------|---------------------|||||-|||||||----|||||--  1    [D]    COG4942 Membrane-bound metallopeptidase
--------------------------|---------------|||||--------|---||-----  1    [S]    COG4950 Uncharacterized protein conserved in bacteria
-------------------||---------------------|||-|----||------||-||-|  1    [M]    COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC
------------------------------------------|||||-||--||||----------  1    [N    U]    COG4967 Tfp pilus assembly protein PilV
----------------|-------------------------|||||-||||||||----------  1    [N    U]    COG4969 Tfp pilus assembly protein, major pilin PilA
------------------------------------------|||||-||||||||----------  1    [L]    COG4973 Site-specific recombinase XerC
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  1    [L]    COG4974 Site-specific recombinase XerD
-------------------------------|--||||----|||||-|-||-------|-|-|--  1    [C    O]    COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
--------------------|-----|||--||-||||----|||||-|-||-------|-|-|--  1    [C    O]    COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
------------------------------|--|||||----|||||-|----------|--|---  1    [R]    COG4989 Predicted oxidoreductase
------------------------------------------|||-|--|---------||-|---  1    [G]    COG4993 Glucose dehydrogenase
------------------------------------------|||||-|-----------------  1    [T]    COG4999 Uncharacterized domain of BarA-like signal transduction histidine kinases
----------------------------------------------|--|--|--|----------  1    [R]    COG5004 P2-like prophage tail protein X
---------------------|----|---------------|||||-||-----|------||--  1    [R]    COG5006 Predicted permease, DMT superfamily
------------------------------------------||||||||||||||----------  1    [K]    COG5007 Predicted transcriptional regulator, BolA superfamily
----------------|-------||----------------|||||-||||||||---|||||||  1    [M]    COG5009 Membrane carboxypeptidase/penicillin-binding protein
------------------------------||---|-------||-|-----|-------------  1    [S]    COG5283 Phage-related tail protein
--|-----------------|----------------|-----||||---||||||----|||---  1    [U    W]    COG5295 Autotransporter adhesin
---------------------------||--------------||-|-------------|-|---  1    [R]    COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
------||----------||-------|||----------------|-------------------  1    [S]    COG5305 Predicted membrane protein
---------------------|--------------------|||||-|-||-||-----------  1    [S]    COG5339 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-------------||----  1    [S]    COG5383 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-----|----------  1    [S]    COG5393 Predicted membrane protein
------------------------------------------|||||--|----------------  1    [D]    COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation
----------------||-------|--------||||----|||||||||||--|||||||||||  1    [O]    COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
-------------------------------------------||||--|-----|----------  1    [S]    COG5435 Uncharacterized conserved protein
------------------------------------------|||-|--------|---|||||--  1    [S]    COG5455 Predicted integral membrane protein
------------------------------------------|||-|--|---------||||---  1    [S]    COG5457 Uncharacterized conserved small protein
-------------------------------------------||-|-----|------|------  1    [S]    COG5471 Uncharacterized conserved protein
------------------------------------------|||-|------------|--|---  1    [S]    COG5475 Uncharacterized small protein
-------------------------------------------|-||--|-----|---||||---  1    [S]    COG5487 Small integral membrane protein
-------------------|----------------------|||-|-------------|-|---  1    [K]    COG5499 Predicted transcription regulator containing HTH domain
-----------------------------------||---------|--------|----------  1    [R]    COG5518 Bacteriophage capsid portal protein
--|-------------------------------|--------||||----|--------------  1    [L]    COG5519 Superfamily II helicase and inactivated derivatives
------------------------------|-----|---------|----------------|--  1    [M]    COG5520 O-Glycosyl hydrolase
------------------------------------------|||||--|-----|----------  1    [R]    COG5544 Predicted periplasmic lipoprotein
---|----|---------------------------------|||-|-------------------  1    [C]    COG5557 Polysulphide reductase
---------------------------||--|--||------|||-|-------------------  1    [R]    COG5562 Phage envelope protein
--------------------------------------------|-|-|-|---------------  1    [S]    COG5566 Uncharacterized conserved protein
------------------------------------------||-||--|-----------|----  1    [N]    COG5567 Predicted small periplasmic lipoprotein
-----------------|------------|-----||----|||||--|----------------  1    [M]    COG5581 Predicted glycosyltransferase
-------------------|-----------------------||-|-----|-------------  1    [S]    COG5606 Uncharacterized conserved small protein
----------------------------------------------|----------||-------  1    [R]    COG5610 Predicted hydrolase (HAD superfamily)
-------------------------------------------||||--|----------------  1    [S]    COG5613 Uncharacterized conserved protein
------------------------------------------|||||-|-||--------------  1    [R]    COG5633 Predicted periplasmic lipoprotein
||||--||||--||----||-------||--|---|-|----||||--|-|---------|||---  0    [E]    COG0076 Glutamate decarboxylase and related PLP-dependent proteins
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  0    [J]    COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
-----||----|-||--|||-------||--|||-|-|----|-----------------------  0    [G]    COG0383 Alpha-mannosidase
--||---------||---||------|||-||||||||----|||---|-----------|--|--  0    [S]    COG0398 Uncharacterized conserved protein
-------------||---||-|||-------|--||||----|||----|--|------||||-||  0    [R]    COG0400 Predicted esterase
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  0    [R]    COG0433 Predicted ATPase
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  0    [R    T    K    L]    COG0515 Serine/threonine protein kinase
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  0    [S]    COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  0    [P]    COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-||||  0    [R]    COG0666 FOG: Ankyrin repeat
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  0    [P]    COG0672 High-affinity Fe2+/Pb2+ permease
-------------||---||-------------------------|--|-||-|||---|||||--  0    [O]    COG0678 Peroxiredoxin
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  0    [R]    COG0679 Predicted permeases
-------------|||--||-|-----||-----|-||----|||----|-----||||-------  0    [R]    COG0699 Predicted GTPases (dynamin-related)
|||-----||------||||-------||-|-||-|||----|||-------------|-------  0    [R]    COG0701 Predicted permeases
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  0    [P]    COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  0    [E]    COG0757 3-dehydroquinate dehydratase II
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0    [E]    COG0804 Urea amidohydrolase (urease) alpha subunit
--------------|---||-|----|-------|--||----||----||----|||-||||---  0    [O]    COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  0    [O]    COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  0    [E]    COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  0    [E]    COG0832 Urea amidohydrolase (urease) beta subunit
|||-----||-----------|---|----|----|||----|||--------------||||---  0    [F]    COG1001 Adenine deaminase
---|----|-|-|||||-|||---||||||---------------|--||||--------------  0    [I]    COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  0    [F]    COG1051 ADP-ribose pyrophosphatase
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  0    [P]    COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  0    [P]    COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
|--|||--|-|||-------||---------|----||----|||------|-||||||-------  0    [C]    COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain
|||||||||||||------|------|||-------------|||----|-----|---|||||--  0    [R]    COG1201 Lhr-like helicases
|||||||||||||||||-------------------------|----------------||-----  0    [R]    COG1204 Superfamily II helicase
|||---||||||-||----|-|----|||-------||-----||---------------|-----  0    [R]    COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
--||--|-|-|--||-|----|||--||||----||||-------|---------|-------|--  0    [H]    COG1232 Protoporphyrinogen oxidase
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  0    [R]    COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
----------|||--------|--||-||-------||----|||----|-----|---||-|---  0    [C]    COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
----------------------||---------------------|--||||-||-----------  0    [C]    COG1347 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD
----------------|----|||-||||-||--||||-------|--||||--------------  0    [M]    COG1388 FOG: LysM repeat
|-|---|---||----|-|--|-----------|--|-----|--|----------|||-------  0    [V]    COG1401 GTPase subunit of restriction endonuclease
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  0    [V]    COG1403 Restriction endonuclease
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  0    [R]    COG1408 Predicted phosphohydrolases
|-||---------|||--||--||||--------|-||----||-----|------------|---  0    [C]    COG1413 FOG: HEAT repeat
||||--|||||||------------|----|--------------|---------|----------  0    [F]    COG1437 Adenylate cyclase, class 2 (thermophilic)
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  0    [R]    COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
-|||--|----------|-||-----|---|----|--||---|||--|--|--|-|||-------  0    [S]    COG1479 Uncharacterized conserved protein
-----------------|||----|------|----||----|||----|-|---|-----|||--  0    [R]    COG1512 Beta-propeller domains of methanol dehydrogenase type
----------------|-||----------------------|||----|-----|----------  0    [P]    COG1513 Cyanate lyase
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  0    [C]    COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
|-|-----|--|-------|||---------------|----|--|--|---|--|----------  0    [H]    COG1541 Coenzyme F390 synthetase
------|------|-----|-------|||||---||--|--|||--------||-----------  0    [G]    COG1554 Trehalose and maltose hydrolases (possible phosphorylases)
---|----|-----------||---------|----||----|||------|-||||||-------  0    [S]    COG1556 Uncharacterized conserved protein
|-|||---|--------|||-------------|--------||||--------|--|--|-||-|  0    [S]    COG1598 Uncharacterized conserved protein
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  0    [G]    COG1621 Beta-fructosidases (levanase/invertase)
------------------||-|--------------|-----||||---------|-----|----  0    [S]    COG1649 Uncharacterized protein conserved in bacteria
--|--------|----|-|-----------------------||||-----|--------------  0    [L]    COG1662 Transposase and inactivated derivatives, IS1 family
----------------------||||----|-----|--------|--||--|--||||----|--  0    [M]    COG1664 Integral membrane protein CcmA involved in cell shape determination
|||---||--||-----||||------------------------|------------|-------  0    [R]    COG1672 Predicted ATPase (AAA+ superfamily)
---||||||--||--------|----||||-------|----|||----------|-------|--  0    [E]    COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  0    [S]    COG1704 Uncharacterized conserved protein
||||||||||||||||-----|-----------------------|---|----------------  0    [T    D]    COG1718 Serine/threonine protein kinase involved in cell cycle control
--|--------------|||-------------------------|-----------|--|-||--  0    [N]    COG1724 Predicted periplasmic or secreted lipoprotein
----------------------||---------------------|--||||-||-----------  0    [C]    COG1726 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA
-|------||----------|---------|-----------|||---------------------  0    [E]    COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  0    [P]    COG1785 Alkaline phosphatase
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  0    [I]    COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
|||-----||-----------------------------------|--------------------  0    [S]    COG1795 Uncharacterized conserved protein
------------------||--||---------------------|--||||-||-------|---  0    [C]    COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
--|-|||||||-|||-----||--------------------|||----|---------|------  0    [J]    COG1859 RNA:NAD 2'-phosphotransferase
------||---------|------------|--|--||-------|------|-------|--|--  0    [G]    COG1874 Beta-galactosidase
------------------||----||----||||-|||-------|--|-|||-------------  0    [M]    COG1876 D-alanyl-D-alanine carboxypeptidase
---||||||--||--------|----||||-------|----|||----------|---|||||--  0    [I]    COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
-|||--|||||||---||-|-------------|||-------||-----------||--------  0    [S]    COG1912 Uncharacterized conserved protein
|||-----||------||--|---------||---|------|||---------------------  0    [I]    COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)
|-------|----------|------|----|||||||----||||------|||||||||-||--  0    [R]    COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
-----------------|--|---------|---||||----|||---------------------  0    [K]    COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding)
----------|||--------|-----||-------||----|||----|-----|---|||||--  0    [O]    COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
---|--|||-|||-----||-------||-|----|||----|||--------------||-|---  0    [K]    COG2002 Regulators of stationary/sporulation gene expression
-------------|-------------||-------------|||---||-------------|--  0    [Q]    COG2015 Alkyl sulfatase and related hydrolases
--------|---|-------|-----|-----|----|----|------||-----||--------  0    [I]    COG2031 Short chain fatty acids transporter
------||---|--------||-----||---|||-||-------|---------|----------  0    [O]    COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
-------------||---|--------||||-----|-----|----------------|--|---  0    [E]    COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  0    [I]    COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
|||||||||||||-------------||--|--------------|---|-|---|---||-||--  0    [N    U]    COG2064 Flp pilus assembly protein TadC
|--------||||--------|-----||-------||----|||----------|---||-||--  0    [R]    COG2068 Uncharacterized MobA-related protein
--------------|-----|------|||||||-|------|||----|--------||||||||  0    [R]    COG2071 Predicted glutamine amidotransferases
----------|||--------|--||-||-------||----|||----|-----|---||-||--  0    [C]    COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
--|---||-|-|-|||-----|----||||----|-||----|--|-------------||||---  0    [S]    COG2120 Uncharacterized proteins, LmbE homologs
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  0    [R]    COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
--|---||----|---||-----------------|---------|--------------------  0    [G]    COG2152 Predicted glycosylase
-------------||------------|||------------||||--||-----|------|---  0    [Q]    COG2175 Probable taurine catabolism dioxygenase
---||||||--||-------||----||||-------|----|||----------|---|||||--  0    [I]    COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  0    [T]    COG2203 FOG: GAF domain
----------------------||---------------------|--||||-||-----------  0    [C]    COG2209 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  0    [P]    COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  0    [E]    COG2303 Choline dehydrogenase and related flavoproteins
------------------|--|--------|-----|------|||--------------------  0    [T]    COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
--------------|--|---|------------||------|||--------------||-|---  0    [Q]    COG2313 Uncharacterized enzyme involved in pigment biosynthesis
---|--||--|||-------||-------------|||-------|--|-------------|--|  0    [E]    COG2317 Zn-dependent carboxypeptidase
-------------------|-|---------------|----|||--------|||---|------  0    [T]    COG2336 Growth regulator
-------------------|-|-----||-|---||||----|||-------|||----|||---|  0    [T]    COG2337 Growth inhibitor
----||------------||-|----||||-------|-------|--|-----------------  0    [K]    COG2345 Predicted transcriptional regulator
-------------||------|-----||--|---|---------|---|-----|---|---|--  0    [T]    COG2365 Protein tyrosine/serine phosphatase
-|-------------------|-------------|--------|-----|-|||-----------  0    [S]    COG2369 Uncharacterized protein, homolog of phage Mu protein gp30
------------------||-|----|-------|--||----|||---||----|||-||||---  0    [O]    COG2371 Urease accessory protein UreE
-------------||-----||---------|--||-|----||||-----|-------||||---  0    [G]    COG2376 Dihydroxyacetone kinase
--------|---|-------||----|----|--||------|||---||-|-------|||||--  0    [R]    COG2388 Predicted acetyltransferase
------||||--|--------------------------------|--------------------  0    [R]    COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain
-||-|||||-|-|-----------------|-----------|||---------------------  0    [C]    COG2414 Aldehyde:ferredoxin oxidoreductase
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  0    [E]    COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
-||---||--||-||----|-|----|---------------||||--||----------------  0    [T]    COG2453 Predicted protein-tyrosine phosphatase
||----||-|---------|-------------------------|---|---||----|-|----  0    [S]    COG2510 Predicted membrane protein
----------------------------------|||-----||||-------||-----------  0    [P]    COG2822 Predicted periplasmic lipoprotein involved in iron transport
--------------------------|||--|-|---|-|--|||--------|||---||--|--  0    [L]    COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------|-----|||---||--||||---||-|---  0    [S]    COG2828 Uncharacterized protein conserved in bacteria
------------------|||----------------------|||---|||||||--|----|--  0    [U]    COG2831 Hemolysin activation/secretion protein
------------------------------------------|||----|-|-||-|||--|----  0    [S]    COG2841 Uncharacterized protein conserved in bacteria
-------------------|-|------------||--------|-----|--||-----------  0    [R]    COG2842 Uncharacterized ATPase, putative transposase
-------------------|-|-------------|------|-------|--||-----|--|--  0    [S]    COG2852 Uncharacterized protein conserved in bacteria
------------------|------|-----------------||---|---------|-------  0    [S]    COG2859 Uncharacterized protein conserved in bacteria
---------------------|-----------------------|--||-|-||||||-|-----  0    [C]    COG2863 Cytochrome c553
----------------------||---------------------|--||||-||-----------  0    [C]    COG2869 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC
----------------------||---------------------|--||||-||-----------  0    [C]    COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF
----------------|-||-------------------------|--||--||||---||-||--  0    [Q]    COG2931 RTX toxins and related Ca2+-binding proteins
---------------------|---------|-|-----------|---|--|---|||----|--  0    [E]    COG2957 Peptidylarginine deiminase and related enzymes
--------------------|-----|-------|--|----||||--|--|-||--------|--  0    [H]    COG2978 Putative p-aminobenzoyl-glutamate transporter
---|||--------------||----------|-|-||-------|--||-----|---|||||--  0    [E]    COG2987 Urocanate hydratase
---------------------------------------------|--||||-||-----------  0    [S]    COG2991 Uncharacterized protein conserved in bacteria
------------------------------|--------------|--||--|-------------  0    [S]    COG3007 Uncharacterized paraquat-inducible protein B
------------------||--------------|-||-------|--||--|--|------||--  0    [S]    COG3011 Uncharacterized protein conserved in bacteria
------------------------|-----------------||||--|-----------------  0    [M    P]    COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance
----------------|-------------------------|-----|-----------------  0    [U]    COG3031 Type II secretory pathway, component PulC
---|--------|-------|---------------------|||---|--|--------------  0    [E]    COG3033 Tryptophanase
--||||---------------------||-------------|-----|----|||---||-|---  0    [L]    COG3039 Transposase and inactivated derivatives, IS5 family
---------------------------------------------|--||||||||----------  0    [N    U]    COG3063 Tfp pilus assembly protein PilF
-------------------||-----|---------------|||---|||-|-------|-||--  0    [R]    COG3093 Plasmid maintenance system antidote protein
------------------------------------------|||----|--|---------||--  0    [S]    COG3128 Uncharacterized iron-regulated protein
------------------------------------------|-----||-----|----------  0    [U]    COG3149 Type II secretory pathway, component PulM
------------------------------------------|--|--||--|--|------||--  0    [U]    COG3156 Type II secretory pathway, component PulK
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  0    [S]    COG3177 Uncharacterized conserved protein
---------------------------||-------------|------|----------------  0    [S]    COG3196 Uncharacterized protein conserved in bacteria
-------------------|-------||||-----||-------|---|-----|---|--|---  0    [Q]    COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
------------------|||----------------------|||---|||||||--|----|--  0    [U]    COG3210 Large exoproteins involved in heme utilization or adhesion
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  0    [P]    COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
-----------------|------------------------|||----|-----|----------  0    [S]    COG3234 Uncharacterized protein conserved in bacteria
-------------------|-|----|---------------|------|----------------  0    [S]    COG3236 Uncharacterized protein conserved in bacteria
--|----------------|-------||--|--||------||||---|-----|----|||---  0    [S]    COG3247 Uncharacterized conserved protein
-----------|-----|-------------|||---|----||||------|------||-----  0    [G]    COG3250 Beta-galactosidase/beta-glucuronidase
-------------------|----------|-----||----|-----||-----|---|||||--  0    [Q    K]    COG3284 Transcriptional activator of acetoin/glycerol metabolism
------------------------------------------|--|--||-------------|--  0    [U]    COG3297 Type II secretory pathway, component PulL
-----------------------------------||-----|-||----|-|-|-----------  0    [S]    COG3299 Uncharacterized homolog of phage Mu protein gp47
---------------------------------------------|----||-||-||-|-||--|  0    [M]    COG3306 Glycosyltransferase involved in LPS biosynthesis
-|-|----|-------|---------|-------||---------|------|--------|||--  0    [L]    COG3316 Transposase and inactivated derivatives
-------------------|------|||||-----|--------|---------|---||-|---  0    [Q]    COG3321 Polyketide synthase modules and related proteins
--|-----|------------------------------------|--||----------|--|--  0    [T]    COG3322 Predicted periplasmic ligand-binding sensor domain
-----------|---------------||--------|----|-----------------|-----  0    [K]    COG3327 Phenylacetic acid-responsive transcriptional repressor
-----------------|---------------|---|-------|--|-----------------  0    [G]    COG3345 Alpha-galactosidase
----|-------------|-----------------||-------|-------------||-|---  0    [S]    COG3347 Uncharacterized conserved protein
--|-||----|------|-|-------------------------|-----|------|-------  0    [S]    COG3350 Uncharacterized conserved protein
---|-------|-------|------|||--||--|-------|||------|--|----------  0    [R]    COG3378 Predicted ATPase
--||-|-----|------||-|---------------|----|------------|----|-----  0    [L]    COG3385 FOG: Transposase and inactivated derivatives
-----------|---------|---------------|----|------------|----|-----  0    [S]    COG3396 Uncharacterized conserved protein
-------------------------------|---|-|-------|--||----------------  0    [S]    COG3397 Uncharacterized protein conserved in bacteria
--------------------||---------|-|||-|----|||-----------------|---  0    [S]    COG3412 Uncharacterized protein conserved in bacteria
-----------------------------------------------|-|--|--|---|------  0    [S]    COG3416 Uncharacterized protein conserved in bacteria
--|---------------------------------------||||---|-|-||----|-|||--  0    [S]    COG3422 Uncharacterized conserved protein
||||||||||||||||---------|-----||||||--------|-----------------|--  0    [I]    COG3425 3-hydroxy-3-methylglutaryl CoA synthase
--||-|---------------|----------||---------|||-------------||||---  0    [L]    COG3436 Transposase and inactivated derivatives
-----|-------------|-|---------------------||--------||-----------  0    [V]    COG3440 Predicted restriction endonuclease
-------------------|----------------------||||---|---------||||---  0    [P]    COG3454 Metal-dependent hydrolase involved in phosphonate metabolism
-------------------------------------------|||--||---------|--|---  0    [T]    COG3456 Uncharacterized conserved protein, contains FHA domain
-----------------|------------|----|---------|--|----------||||---  0    [G]    COG3459 Cellobiose phosphorylase
---------------------|---------------|----|------------|----|-----  0    [Q]    COG3460 Uncharacterized enzyme of phenylacetate metabolism
--------------------|---|--------------------|-----|------|--|----  0    [P]    COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport
-------------------------------|--|-------||||------------|-------  0    [S]    COG3477 Predicted periplasmic/secreted protein
--------------------------|------------------|---|-----|---|||||||  0    [Q]    COG3485 Protocatechuate 3,4-dioxygenase beta subunit
---|----------|----|-----------------|-------|---|-----|----|-|---  0    [Q]    COG3486 Lysine/ornithine N-monooxygenase
--------------|------------------------------|---|-----|--|---||--  0    [R]    COG3491 Isopenicillin N synthase and related dioxygenases
------------------------------||----||----|-----------------|--|--  0    [G]    COG3507 Beta-xylosidase
---------------------------------------------|--||-----|------|---  0    [O]    COG3531 Predicted protein-disulfide isomerase
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  0    [L]    COG3547 Transposase and inactivated derivatives
--------------------|-----|---------------|||---|-|--|-|---||-||--  0    [R]    COG3550 Uncharacterized protein related to capsule biosynthesis enzymes
------------------------------|||-|--------||-----|---|-----------  0    [K]    COG3561 Phage anti-repressor protein
-------------------|-|---------|-|-----------|--|----------|--||--  0    [S]    COG3575 Uncharacterized protein conserved in bacteria
--|----------------------------------------||-----|-----||---|----  0    [S]    COG3586 Uncharacterized conserved protein
--|----------------------------|---|------|||-----------------|---  0    [S]    COG3592 Uncharacterized conserved protein
------||----------------------||---|||-------|--------------------  0    [S]    COG3595 Uncharacterized conserved protein
------------------||----------------------|||---|-----|--|--------  0    [R]    COG3596 Predicted GTPase
-------------------------------||--|-------|||---||-|--------|----  0    [K]    COG3617 Prophage antirepressor
---------------------------------------------|---|-----|--|||||---  0    [R]    COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3624 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3625 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3626 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3627 Uncharacterized enzyme of phosphonate metabolism
---------------------------------------------|----|-|--|----|--|--  0    [K]    COG3636 Predicted transcriptional regulator
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  0    [P]    COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  0    [P]    COG3639 ABC-type phosphate/phosphonate transport system, permease component
-------------------------------||-|||------|||--------------------  0    [S]    COG3645 Uncharacterized phage-encoded protein
-------------------------------|-|-||------||-----||--------------  0    [S]    COG3646 Uncharacterized phage-encoded protein
------------------------------------------|||---|--|--------------  0    [S]    COG3647 Predicted membrane protein
-------------------|-------------------------|----|-|--|----|--|--  0    [S]    COG3657 Uncharacterized protein conserved in bacteria
-------------------|-|-----||--------------|||--||--|--|---|||||--  0    [R]    COG3668 Plasmid stabilization system protein
---------------------|---------------------||--------||-----------  0    [S]    COG3680 Uncharacterized protein conserved in bacteria
------------------------------------------|||-----|--|---------|--  0    [S]    COG3692 Uncharacterized protein conserved in bacteria
---------------------|--------------------|||--------------||||---  0    [S]    COG3698 Predicted periplasmic protein
-------------||---------------------|-----|||----------|---|||||--  0    [P]    COG3703 Uncharacterized protein involved in cation transport
------------------------------------------||||---|---------||||---  0    [P]    COG3709 Uncharacterized component of phosphonate metabolism
------------------------------------------|------|-----|---||--|--  0    [P    T]    COG3712 Fe2+-dicitrate sensor, membrane component
-------------------------------------------|||---|-----|----|-|---  0    [P]    COG3720 Putative heme degradation protein
-------------------------------------------|||--|--|-------|------  0    [P]    COG3721 Putative heme iron utilization protein
-------------------------------||-||||----|||---------------------  0    [L]    COG3723 Recombinational DNA repair protein (RecE pathway)
-------------------------------||-|||------|||---|------------|---  0    [L]    COG3728 Phage terminase, small subunit
-----------|--|----|-|--------------------|-------------------|---  0    [Q]    COG3733 Cu2+-containing amine oxidase
---------------------|-----------------------|---|---------|||||--  0    [E]    COG3741 N-formylglutamate amidohydrolase
---------------------------||-||-----------||---------------------  0    [L]    COG3747 Phage terminase, small subunit
------------------------------------------|||----|-----|----|||---  0    [S]    COG3753 Uncharacterized protein conserved in bacteria
------------------------------------------|---------|---------|---  0    [S]    COG3756 Uncharacterized protein conserved in bacteria
------------------------------||||--------|||-------|------||||---  0    [M]    COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase)
--------------------|-----------|---------||||---|-----|---||||---  0    [S]    COG3758 Uncharacterized protein conserved in bacteria
------------------------------------------|-||----|--||-----------  0    [S]    COG3778 Uncharacterized protein conserved in bacteria
------------------------------------------|----------||-------|---  0    [S]    COG3779 Uncharacterized protein conserved in bacteria
------------------||-|---------------------|||-------------|---|--  0    [P]    COG3793 Tellurite resistance protein
---|---------------------------------------||-----------------|---  0    [E]    COG3799 Methylaspartate ammonia-lyase
--------------------------------||-----------|---------|--|----|--  0    [S]    COG3817 Predicted membrane protein
--------------------------------||-----------|---------|--|----|--  0    [S]    COG3819 Predicted membrane protein
------------------------------------|------|||-----|---------||---  0    [R]    COG3822 ABC-type sugar transport system, auxiliary component
---------------------|----|-----|------------|-----------------|--  0    [O]    COG3823 Glutamine cyclotransferase
-------------------|||--------------------|||--------------|--|---  0    [S]    COG3831 Uncharacterized conserved protein
-----------------|------------|-----||-------|--------------------  0    [G]    COG3867 Arabinogalactan endo-1,4-beta-galactosidase
---------------------------------------------|---|--|-------------  0    [R]    COG3907 PAP2 (acid phosphatase) superfamily protein
---------------------------------------------|---|-----|---||-|---  0    [T    Q]    COG3916 N-acyl-L-homoserine lactone synthetase
--------------------------------------------||--|||---------------  0    [R]    COG3941 Mu-like prophage protein
-------------------------------------|-------|-------------||||---  0    [I]    COG3963 Phospholipid N-methyltransferase
-------------------------------------|-------|--|----------||-----  0    [P]    COG3965 Predicted Co/Zn/Cd cation transporters
-----------|---------------------------------|-------------||-||--  0    [R]    COG3970 Fumarylacetoacetate (FAA) hydrolase family protein
-----------------|---------------------------|-----|--------|-----  0    [R]    COG4099 Predicted peptidase
--|----------------|-------------------------|--||-----|---|--|---  0    [S]    COG4104 Uncharacterized conserved protein
---------------------|-----||-------------||||---|---------||||---  0    [R]    COG4106 Trans-aconitate methyltransferase
-------------------|----------------------||||---|---------||-|---  0    [P]    COG4107 ABC-type phosphonate transport system, ATPase component
---------------------|--------|------------|||--------------------  0    [R]    COG4110 Uncharacterized protein involved in stress response
---------------------------------------------|--||----------------  0    [R]    COG4128 Zonula occludens toxin
------------------------------------------||||--|----------|||----  0    [R]    COG4134 ABC-type uncharacterized transport system, periplasmic component
------------------------------------------|||---|-----------|-----  0    [R]    COG4135 ABC-type uncharacterized transport system, permease component
------------------------------------------|||---|-----------|-----  0    [R]    COG4136 ABC-type uncharacterized transport system, ATPase component
-------------------------------------|----|||-----||--------------  0    [R]    COG4146 Predicted symporter
-------------------------------------------|||-----|----------|---  0    [R]    COG4158 Predicted ABC-type sugar transport system, permease component
-------------|----||-------|||------------|||-----||-|-|---||||---  0    [R]    COG4178 ABC-type uncharacterized transport system, permease and ATPase components
------------------------------------------|||-------|------|------  0    [S]    COG4197 Uncharacterized protein conserved in bacteria, prophage-related
-------------------------------------|-|--||||----|----|---||||---  0    [G]    COG4213 ABC-type xylose transport system, periplasmic component
-------------------------------------|-|--||||----|----|---||||---  0    [G]    COG4214 ABC-type xylose transport system, permease component
------------------||-|-----------------------|------------|||-|---  0    [S]    COG4222 Uncharacterized protein conserved in bacteria
-------------------|-|---------------------||-------|--|----|----|  0    [S]    COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters
--------------------------------------------||----|--||-----------  0    [R]    COG4228 Mu-like prophage DNA circulation protein
-----|-----|---------------||-------------|||---------------------  0    [C]    COG4237 Hydrogenase 4 membrane component (E)
-------------------|----------------------||||----------|---------  0    [R]    COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain
-------------------|-|--------------------|||---------------------  0    [R]    COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains
---------------------------------------------|---|-----|----------  0    [S]    COG4253 Uncharacterized protein conserved in bacteria
-------------------------------------------||-------|--|----------  0    [R]    COG4258 Predicted exporter
---------------------------------------------|---|---|||----------  0    [S]    COG4259 Uncharacterized protein conserved in bacteria
-------------------------------------------||-------|--|----------  0    [R]    COG4261 Predicted acyltransferase
---|---------------|--------------|--|-------|---------|----|-----  0    [Q]    COG4264 Siderophore synthetase component
--|------------------|-----------|--------|--|------------|-------  0    [V]    COG4268 McrBC 5-methylcytosine restriction system component
-----------------|---------------------------|-------------||-----  0    [S]    COG4289 Uncharacterized protein conserved in bacteria
------------------------------|--------------|-------||-----------  0    [S]    COG4304 Uncharacterized protein conserved in bacteria
------------------------------||-------------|----------------|---  0    [S]    COG4331 Predicted membrane protein
----------------------------------|--------||---------------|-----  0    [S]    COG4333 Uncharacterized protein conserved in bacteria
---------------------|----------------------|-----|---------------  0    [R]    COG4373 Mu-like prophage FluMu protein gp28
--------------------------------------------||----|--||-----------  0    [R]    COG4379 Mu-like prophage tail protein gpP
---------------------------------------------|---|---|||----------  0    [S]    COG4380 Uncharacterized protein conserved in bacteria
--------------------------------------------||----|--||-----------  0    [S]    COG4381 Mu-like prophage protein gp46
--------------------------------------------|-----|--||-----------  0    [S]    COG4382 Mu-like prophage protein gp16
--------------------------------------------|-----|--||-----------  0    [S]    COG4383 Mu-like prophage protein gp29
--------------------------------------------||----|--||-----------  0    [S]    COG4384 Mu-like prophage protein gp45
--------------------------------------------||----|--||-----------  0    [R]    COG4386 Mu-like prophage tail sheath protein gpL
--------------------------------------------|-----|--||-----------  0    [S]    COG4387 Mu-like prophage protein gp36
--------------------------------------------|-----|--||-----------  0    [R]    COG4388 Mu-like prophage I protein
--------------------|------------------------|-----|------|-------  0    [S]    COG4393 Predicted membrane protein
--------------------------------------------|-----|---|-----------  0    [R]    COG4396 Mu-like prophage host-nuclease inhibitor protein Gam
--------------------------------------------|-----|---|-----------  0    [R]    COG4397 Mu-like prophage major head subunit gpT
----------------------------------|--|-------|---|----------------  0    [S]    COG4408 Uncharacterized protein conserved in bacteria
----------------------------------|----------|---|-----------|----  0    [E]    COG4413 Urea transporter
------------------------------|-------------|-----|---------------  0    [R]    COG4416 Mu-like prophage protein Com
---------------------------------------------|---|--|-------------  0    [S]    COG4517 Uncharacterized protein conserved in bacteria
--------------------------------------------|---|-|---------------  0    [S]    COG4518 Mu-like prophage FluMu protein gp41
---------------------------------------------|--||----------------  0    [S]    COG4519 Uncharacterized protein conserved in bacteria
------------------------------------------||||---|----------|-|---  0    [P]    COG4521 ABC-type taurine transport system, periplasmic component
------------------------------------------||||---|---------||-|---  0    [P]    COG4525 ABC-type taurine transport system, ATPase component
--------------------------|||-----|-------|||--------------||||---  0    [S]    COG4529 Uncharacterized protein conserved in bacteria
---------------------------------------------|-------------|||||--  0    [H]    COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
---------------------|----|----------------|||--||-|-------||-|---  0    [P]    COG4558 ABC-type hemin transport system, periplasmic component
---------------------|----|----------------|||--||---------||-|---  0    [P]    COG4559 ABC-type hemin transport system, ATPase component
---------------------------||-------------|||----------|----------  0    [Q]    COG4569 Acetaldehyde dehydrogenase (acetylating)
----------------|--------------||-|||-----|||---------------------  0    [L]    COG4570 Holliday junction resolvase
--|------------------------||-----||-|-----|||---------|---||-|---  0    [L]    COG4584 Transposase and inactivated derivatives
-------------------------------------------||---|---------|-|-----  0    [R]    COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain
--------------------|---------------------||||--||-|--------|-----  0    [R]    COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase
---------------------------------------------|--||----------------  0    [R]    COG4590 ABC-type uncharacterized transport system, permease component
----------------------------------|-|-----|--------|--------------  0    [P]    COG4594 ABC-type Fe3+-citrate transport system, periplasmic component
-------------------|----------------------|||---|----------||||---  0    [E]    COG4597 ABC-type amino acid transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0    [P]    COG4604 ABC-type enterochelin transport system, ATPase component
--------------------------|------||-||-------|--|----||---||-|----  0    [P]    COG4605 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0    [P]    COG4606 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  0    [P]    COG4607 ABC-type enterochelin transport system, periplasmic component
----------------|----------------------------|---|---------||-||||  0    [R]    COG4618 ABC-type protease/lipase transport system, ATPase and permease components
------------------------------||--||------|||-----------------|---  0    [R]    COG4626 Phage terminase-like protein, large subunit
---------------------|-----------------------|--|-----------------  0    [S]    COG4628 Uncharacterized conserved protein
-----------------|||------|||-------------||||---|-----|---|||||--  0    [P    R]    COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
---------------------|--------|--------------|-------------|--|---  0    [L]    COG4644 Transposase and inactivated derivatives, TnpA family
-------------------------------------------||---------||----------  0    [S]    COG4648 Predicted membrane protein
---------------------------||--------------||----------|---|--||--  0    [R]    COG4653 Predicted phage phi-C31 gp36 major capsid-like protein
------------------||-|----|----------|-------|---|-----|---||-|---  0    [R]    COG4674 Uncharacterized ABC-type transport system, ATPase component
------------------------------------------|||----|-----|----------  0    [S]    COG4676 Uncharacterized protein conserved in bacteria
------------------||-----------------------||----------|----------  0    [G]    COG4678 Muramidase (phage lambda lysozyme)
-------------------|-------||----------------|--------------------  0    [S]    COG4683 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-----|----------  0    [S]    COG4685 Uncharacterized protein conserved in bacteria
-------------------------------------------||------|---|----------  0    [S]    COG4688 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-----|----------  0    [Q]    COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis
------------------------------|||---------|||----------|---|-|||--  0    [S]    COG4695 Phage-related protein
-------------------------------------------||----------|-------|--  0    [S]    COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats
---------------------------------------------|--|-||--------------  0    [S]    COG4701 Uncharacterized protein conserved in bacteria
-------------||------------------------------|--------------|||---  0    [S]    COG4702 Uncharacterized conserved protein
-------------------------------------------||--------|-|----------  0    [I]    COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase
-------------------|-------------------------|-------------|------  0    [R]    COG4734 Antirestriction protein
--------------------------|---------------|||-----------------|---  0    [S]    COG4763 Predicted membrane protein
------------------------------------------|------|------||--|--|--  0    [P]    COG4772 Outer membrane receptor for Fe3+-dicitrate
------------------------------------------|||----|--|----------|--  0    [P]    COG4774 Outer membrane receptor for monomeric catechols
-------------------|----------------------||||---|---------||-|---  0    [P]    COG4778 ABC-type phosphonate transport system, ATPase component
---|----------------|----------------------||---------------------  0    [E]    COG4865 Glutamate mutase epsilon subunit
--------------------|--------------|------|-----------------------  0    [S]    COG4884 Uncharacterized protein conserved in bacteria
--------------------------|------------------|------|-------------  0    [S]    COG4913 Uncharacterized protein conserved in bacteria
--------------------------|------------------|------|-------------  0    [S]    COG4924 Uncharacterized protein conserved in bacteria
--|----------------||------------------------|-----|---------|----  0    [S]    COG4929 Uncharacterized membrane-anchored protein
--------------------------|------|---------||---------------------  0    [S]    COG4951 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-|---|---||-||--  0    [O    U]    COG4960 Flp pilus assembly protein, protease CpaA
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG4961 Flp pilus assembly protein TadG
||----||-|----------------|||-|--------------|---|-||--|---||-||--  0    [U]    COG4962 Flp pilus assembly protein, ATPase CpaF
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG4963 Flp pilus assembly protein, ATPase CpaE
--------------------------|||----------------|---|-|---|---||-||--  0    [U]    COG4965 Flp pilus assembly protein TadB
-------------------------------------------||----|-----|---|||||--  0    [K]    COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
--------------------|------------------------|-----|--------------  0    [S]    COG4984 Predicted membrane protein
---------------------------------------------|--||----------------  0    [P]    COG4985 ABC-type phosphate transport system, auxiliary component
--------------------------------------------|-----|--||-----------  0    [R]    COG5003 Mu-like prophage protein gp37
--------------------------------------------|-----|---|-----------  0    [R]    COG5005 Mu-like prophage protein gpG
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG5010 Flp pilus assembly protein TadD, contains TPR repeats
-------------||------------------------------|--------------------  0    [T]    COG5212 Low-affinity cAMP phosphodiesterase
-------------||------------------------------|---------|---|||||||  0    [O]    COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components
--|--------------|---------------------------|--------------------  0    [S]    COG5276 Uncharacterized conserved protein
---------------------------------------------|---|-----|---||-|---  0    [S]    COG5373 Predicted membrane protein
---------------------------------------------|---------|------||--  0    [S]    COG5419 Uncharacterized conserved protein
---------------------------------------------|---|-----|---|--|--|  0    [S]    COG5430 Uncharacterized secreted protein
-------------------|------------|---------|||---------------|-----  0    [L]    COG5433 Transposase
---------------------------------------------|--------------|||---  0    [S]    COG5441 Uncharacterized conserved protein
------------------------------------------|||----|-----|----------  0    [S]    COG5445 Predicted secreted protein
-------------------------------------|-------|-------------|---|--  0    [S]    COG5460 Uncharacterized conserved protein
---------------------------------------------|---------|--|-------  0    [S]    COG5472 Predicted small integral membrane protein
------------------------------------------|||---------------|-|---  0    [S]    COG5507 Uncharacterized conserved protein
--------------------------|---------------|||----|-----|----------  0    [Q]    COG5517 Small subunit of phenylpropionate dioxygenase
--|------------------------------------------|-----------------|--  0    [R]    COG5529 Pyocin large subunit
------------------------------------------|---------||------------  0    [S]    COG5532 Uncharacterized conserved protein
---------------------------------------------|--------------|-|---  0    [S]    COG5556 Uncharacterized conserved protein
---------------------------------------------|--------------|-|---  0    [R]    COG5564 Predicted TIM-barrel enzyme, possibly a dioxygenase
------------------------------------------|||----------|---||-----  0    [S]    COG5569 Uncharacterized conserved protein
------------------------------|------------||----------|---|------  0    [R]    COG5614 Bacteriophage head-tail adaptor
---------------------------------------------|--------------|||---  0    [R]    COG5618 Predicted periplasmic lipoprotein
---------------------------------------------|--------------|-|---  0    [S]    COG5642 Uncharacterized conserved protein
---------------------------||----------------|--------------|-|---  0    [S]    COG5654 Uncharacterized conserved protein

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