(Bme) Brucella melitensis
generin.cgi	Functional categories
	Fun	All	J	A	K	L	B	D	Y	V	T	M	N	Z	W	U	O	C	G	E	F	H	I	P	Q	R	S
	COGs	1,653	138	-	66	77	1	19	-	15	34	97	28	-	1	44	87	114	84	167	59	107	52	102	35	192	239
	proteins	2,767	169	-	210	151	1	27	-	42	105	180	33	-	2	55	125	196	216	399	72	137	122	191	76	379	268
	Distribution of COGs by number of proteins
	proteins	1	2	3	4	5	6	7	8	9	10	11	12	13	14	16	21	23	25	26	31
	COGs	1217	247	76	34	18	11	9	12	9	8	2	1	2	1	1	1	1	1	1	1

Co-ocurrences in sister taxa	0	1	2	3
order Rhizobiales	55	74	132	1392

+    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    +    ++    +    +    +    +
||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 31    [G    E    P    R]    COG0477 Permeases of the major facilitator superfamily
--|---------------||-|----||-----|---------------------|---|-|||-- 26    [L]    COG3293 Transposase and inactivated derivatives
--|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 25    [I    Q    R]    COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 23    [K]    COG0583 Transcriptional regulator
||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 21    [C]    COG1012 NAD-dependent aldehyde dehydrogenases
|-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 16    [T]    COG0642 Signal transduction histidine kinase
|-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||-- 14    [R]    COG0673 Predicted dehydrogenases and related proteins
-|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 13    [E]    COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
|||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 13    [K]    COG1846 Transcriptional regulators
|-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||-- 12    [E]    COG0346 Lactoylglutathione lyase and related lyases
|-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 11    [G    E    R]    COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily
----------------||||||--|||---|-||||||----|||||-|||||||||||||||||| 11    [M]    COG0845 Membrane-fusion protein
||||||||||||||||||||||---|||||||||||||----|||||-|||||||||||||||||| 10    [M]    COG0438 Glycosyltransferase
----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 10    [T    K]    COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---||||||| 10    [I]    COG1024 Enoyl-CoA hydratase/carnithine racemase
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||--- 10    [E    P]    COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
|||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||-- 10    [K]    COG1522 Transcriptional regulators
----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||-- 10    [K]    COG1802 Transcriptional regulators
---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||-- 10    [I]    COG1960 Acyl-CoA dehydrogenases
--|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 10    [L]    COG2801 Transposase and inactivated derivatives
|-||||--|-|||||||||||||||-||||||||||||----||||||||||||||||||||||||  9    [L    R]    COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
--|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||---  9    [E    P]    COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components
--|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||---  9    [E]    COG0747 ABC-type dipeptide transport system, periplasmic component
---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||---  9    [G]    COG1175 ABC-type sugar transport systems, permease components
|-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||--  9    [K]    COG1309 Transcriptional regulator
-----------------||||-----|||-||-|||||----|||||-||||||||--||||||--  9    [K]    COG2207 AraC-type DNA-binding domain-containing proteins
||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||--  9    [E]    COG2303 Choline dehydrogenase and related flavoproteins
------------------------------------------|||||---||-||----|||||||  9    [M]    COG3637 Opacity protein and related surface antigens
|||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||---  9    [G]    COG3839 ABC-type sugar transport systems, ATPase components
---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||---  8    [G]    COG0395 ABC-type sugar transport system, permease component
-|------|-|||----|||||-----------|--------|||||--|-----|--|||||---  8    [E]    COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
--|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||---  8    [E    P]    COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||--  8    [M    G]    COG0451 Nucleoside-diphosphate-sugar epimerases
--|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||--  8    [E]    COG0665 Glycine/D-amino acid oxidases (deaminating)
--|-----|-|-|----||||||||-||||||||||||----|||||-||||-|||||||||||||  8    [E    T]    COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
-----------------|--|---|||----|----||-|--|||||-||||---|---|||||--  8    [G]    COG1129 ABC-type sugar transport system, ATPase component
|-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---|||||||  8    [K]    COG1396 Predicted transcriptional regulators
---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||---  8    [G]    COG1653 ABC-type sugar transport system, periplasmic component
----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||--  8    [T]    COG2199 FOG: GGDEF domain
|-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||--  8    [T]    COG2202 FOG: PAS/PAC domain
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  8    [E]    COG4177 ABC-type branched-chain amino acid transport system, permease component
--||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||--  7    [C]    COG0277 FAD/FMN-containing dehydrogenases
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  7    [E]    COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
-|------|-|||----|||||----|------|---|----|||||--|-----|--|||||---  7    [E]    COG0559 Branched-chain amino acid ABC-type transport system, permease components
-------------||---||------------||--------|||||-||||||||---|||||||  7    [O]    COG0625 Glutathione S-transferase
-------------||||||||||||-|||||||-||||----|||||-||||||||--||||||--  7    [T]    COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
--|-------------||||||---|----|---|-||----|||||-||||||||||||||||||  7    [V]    COG0841 Cation/multidrug efflux pump
--||--||--||-|||||||||||--||||||||||||||||||||||||||||||||||||||||  7    [V]    COG1132 ABC-type multidrug transport system, ATPase and permease components
---|------------||---|----|||-------||----|||||-||||---|--||||||--  7    [K]    COG1414 Transcriptional regulator
--|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||---  7    [E]    COG4608 ABC-type oligopeptide transport system, ATPase component
||||||||||||||||||||||---||||||||||||||||||||||-||||||||||||||||||  6    [M]    COG0463 Glycosyltransferases involved in cell wall biogenesis
|||||||||||||||||||||||||-||||||||||||----||||||||||||||||||||||||  6    [Q    R]    COG0500 SAM-dependent methyltransferases
---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---|||||||  6    [C]    COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes
|||||||||--||---||||||||--||||||||||||||--|||||-||||||||||||||||||  6    [L]    COG0582 Integrase
--||||--|-|||||||-||||---|||||||-||||||||||||||-||||||||||||||||||  6    [R]    COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 
|-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||--  6    [T]    COG0784 FOG: CheY-like receiver
--|-----|-------|-||||----||||||||||||----|||||-||||||||||||||||||  6    [K]    COG0789 Predicted transcriptional regulators
-----------------|--|-----|--|-|----||----|||||-||||---|---|||||--  6    [G]    COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components
-----------------|||------|||||-----||----|||-|-||---|||---||||---  6    [S]    COG1376 Uncharacterized protein conserved in bacteria
--|--------------|--|---|-|--|||----||----|||||-||||---|---|||||--  6    [G]    COG1879 ABC-type sugar transport system, periplasmic component
--||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||--  6    [E]    COG3842 ABC-type spermidine/putrescine transport systems, ATPase components
||||----|||||||-||||||||||||||||||||||||||---|---|---|||||||||||||  5    [J]    COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases
|-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||--  5    [I]    COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
|||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-|  5    [K    R]    COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--||||||||  5    [G]    COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family
|||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||--  5    [G]    COG0524 Sugar kinases, ribokinase family
--||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||--  5    [C    R]    COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases
|||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||--  5    [K]    COG0640 Predicted transcriptional regulators
-------------||---||-|----|||-----|-||----|||||-||-|||||---|||||||  5    [H    C]    COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
|||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||--  5    [R]    COG0730 Predicted permeases
----------------||||----||----||||-|||----||||||||||||||||||||||||  5    [M]    COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||--  5    [E]    COG1177 ABC-type spermidine/putrescine transport system, permease component II
||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---|||||||  5    [C]    COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
----------------||||-|----|---||--||------|||||-||||||||---|||||||  5    [S]    COG1434 Uncharacterized conserved protein
-----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||--  5    [K]    COG1609 Transcriptional regulators
--------------------|-||||||||||||||||----|||||-||||||||---|||||||  5    [M]    COG1686 D-alanyl-D-alanine carboxypeptidase
---------------------|----|||||----|||----|||||-||||-|||---|||||--  5    [K]    COG2186 Transcriptional regulators
-------------------|-|----|||-||||||||||--|||||-||-----|---|||||--  5    [K]    COG2188 Transcriptional regulators
-----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||---  5    [E]    COG4166 ABC-type oligopeptide transport system, periplasmic component
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  4    [C]    COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
|||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||--  4    [E]    COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase
||||----|||--||-||||||----||||||||||||----|||||-||||||||||||||||||  4    [E    H]    COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase
-|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||--  4    [H]    COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-|||||||  4    [I]    COG0183 Acetyl-CoA acetyltransferase
-|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||--  4    [D]    COG0239 Integral membrane protein possibly involved in chromosome condensation
---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||--  4    [J]    COG0251 Putative translation initiation inhibitor, yjgF family
-------------||-||||||||--||||||||||||----||||||||||||||||||||||||  4    [I    Q]    COG0304 3-oxoacyl-(acyl-carrier-protein) synthase
|||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-|||||||  4    [L    K    J]    COG0513 Superfamily II DNA and RNA helicases
|||||||||||||||-||||||||-|||||||||||||----|||||-||||||||||||||||||  4    [R]    COG0517 FOG: CBS domain
--|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||--  4    [R]    COG0523 Putative GTPases (G3E family)
|||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---|||||||  4    [T]    COG0589 Universal stress protein UspA and related nucleotide-binding proteins
-||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||--  4    [P]    COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component
-||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||--  4    [P]    COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components
--|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||--  4    [P]    COG0735 Fe2+/Zn2+ uptake regulation proteins
----------------||||||--||||||||--||||----||||||||||||||||||||||||  4    [M]    COG0739 Membrane proteins related to metalloendopeptidases
-------------|||||||||--||----||||||||----||||||||||||||||||||||||  4    [O]    COG0760 Parvulin-like peptidyl-prolyl isomerase
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4    [E]    COG0765 ABC-type amino acid transport system, permease component
-------------|||-----|--------------------|||||-||||-|||||||||||--  4    [R]    COG0790 FOG: TPR repeat, SEL1 subfamily
|-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||--  4    [V]    COG0842 ABC-type multidrug transport system, permease component
||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||--  4    [R]    COG1011 Predicted hydrolase (HAD superfamily)
---|||----||||||--||-|||---||--|||||||-|||-------|-----|---|||||||  4    [C]    COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
--|-----|-|-|----|||||||--|---||||||||----|||||-|||--|||||||||||||  4    [E]    COG1126 ABC-type polar amino acid transport system, ATPase component
---|||--|-|||-------||-----||||---|-||----|||||-||-----|---|||||||  4    [I]    COG1250 3-hydroxyacyl-CoA dehydrogenase
---|------------||--||----|||||||-||||----||||||||||||||---|||||||  4    [K]    COG1278 Cold shock proteins
----------------||--||----|---||||||||----|||||-||||-|||---||||---  4    [K    G]    COG1349 Transcriptional regulators of sugar metabolism
----------------|-----------------|-|-----|||||-|||--|||---|||||||  4    [V]    COG1566 Multidrug resistance efflux pump
--|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---|||||||  4    [V]    COG1680 Beta-lactamase class C and other penicillin binding proteins
-----|--|-||---------|-----||-------------|||-|--|-----|---|||||--  4    [C]    COG1804 Predicted acyl-CoA transferases/carnitine dehydratase
------------------||-|----|||-||||||||----|||||-||||||||---|||||--  4    [T    K]    COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
|-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||--  4    [P]    COG2217 Cation transport ATPase
-------------||-----||---------|--||-|----||||-----|-------||||---  4    [G]    COG2376 Dihydroxyacetone kinase
--------------------------|||-------------|||||-||-|||||---|||||--  4    [M]    COG2951 Membrane-bound lytic murein transglycosylase B
-------------------------------------|-|--||||----|----|---||||---  4    [G]    COG4213 ABC-type xylose transport system, periplasmic component
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  3    [E]    COG0006 Xaa-Pro aminopeptidase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3    [J]    COG0008 Glutamyl- and glutaminyl-tRNA synthetases
|||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||---  3    [E]    COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family
|||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||--  3    [E]    COG0019 Diaminopimelate decarboxylase
|||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||--  3    [F]    COG0044 Dihydroorotase and related cyclic amidohydrolases
|||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||--  3    [H    E]    COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases
|||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||--  3    [E]    COG0119 Isopropylmalate/homocitrate/citramalate synthases
|||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  3    [E    G]    COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  3    [E]    COG0169 Shikimate 5-dehydrogenase
|||||||||||||||-||||-|----||||-|||||||----|||||-||||||||||||||||||  3    [E]    COG0174 Glutamine synthetase
|||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||--  3    [Q]    COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
|-||------||-||-||||||||||||||||||||||----||||||||||||||||||||||||  3    [O]    COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
|||||||||||||---|||||-||--||||||||||||----||||||||||||||||||||||||  3    [E    M]    COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase
|||||||||||||||-||||||--||||||||||---|-|--||||||||||||||||||||||||  3    [O]    COG0330 Membrane protease subunits, stomatin/prohibitin homologs
-||-||--||-|------||----------|-----------|||-|-||||-|||||||||||--  3    [C]    COG0348 Polyferredoxin
||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-|  3    [L]    COG0350 Methylated DNA-protein cysteine methyltransferase
---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||--  3    [E]    COG0404 Glycine cleavage system T protein (aminomethyltransferase)
|||||||||||||||-|||||||||-||||||||||||----|||||-||||||||||||||||||  3    [E]    COG0436 Aspartate/tyrosine/aromatic aminotransferase
|||||||||--|-|||||||||||||----||||||||----|||||-||-|||||||||||||||  3    [R]    COG0457 FOG: TPR repeat
||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-||  3    [M]    COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase
-------------|||--||||||||||||||||||||-|--||||||||||||||||||||||||  3    [R]    COG0488 ATPase components of ABC transporters with duplicated ATPase domains
||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||--  3    [R]    COG0491 Zn-dependent hydrolases, including glyoxylases
|||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  3    [O    C]    COG0526 Thiol-disulfide isomerase and thioredoxins
|-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||--  3    [R]    COG0546 Predicted phosphatases
--------|----||-|||||||||||||||||||||||||||||||-||||||||||||||||||  3    [J]    COG0566 rRNA methylases
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  3    [K]    COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  3    [L]    COG0593 ATPase involved in DNA replication initiation
----------|-|||-||||||---|-|||||||||||----|||||-|||||--|||||||||||  3    [R]    COG0612 Predicted Zn-dependent peptidases
|||||||||||||---||||||-||-|||||---|-||----||||||||||||||||||||||||  3    [J]    COG0621 2-methylthioadenine synthetase
-|--|||||||||||-||--||-|--||||||||||||----||||||||||||||||||||||||  3    [E]    COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases
--||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||--  3    [E]    COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases
----------------|||||||||||||-|||||||||---||||||||||||||||||||||||  3    [H]    COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases
--|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||--  3    [R]    COG0637 Predicted phosphatase/phosphohexomutase
---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||--  3    [E]    COG0687 Spermidine/putrescine-binding periplasmic protein
|||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||--  3    [R]    COG0714 MoxR-like ATPases
--|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||--  3    [G]    COG0726 Predicted xylanase/chitin deacetylase
-----------------|||||----||||||||||||----||||||||||||||||||||||--  3    [M]    COG0744 Membrane carboxypeptidase (penicillin-binding protein)
----||----------||||||||||-|||||||||||||||||||||||||||||||||||||||  3    [L]    COG0776 Bacterial nucleoid DNA-binding protein
|||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||--  3    [C]    COG0778 Nitroreductase
-----------------|---|||||||||||||||||||||||||||||||||||||||||||||  3    [K]    COG0782 Transcription elongation factor
----|---|----||||||--||||-|||-||||||||----||||||||||||||||||||||||  3    [L]    COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
|||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||  3    [G]    COG1109 Phosphomannomutase
-||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||--  3    [P]    COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component
|-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||--  3    [V]    COG1131 ABC-type multidrug transport system, ATPase component
---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||--  3    [E]    COG1176 ABC-type spermidine/putrescine transport system, permease component I
---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||---  3    [P]    COG1178 ABC-type Fe3+ transport system, permease component
|-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||--  3    [E]    COG1280 Putative threonine efflux protein
--|||||||-|||---||||||--|--|||||||--------------|-|--|||||||||||||  3    [L]    COG1573 Uracil-DNA glycosylase
-----------------|||||--|-||||||--||||----|||||-||||||||---|||||--  3    [K]    COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
---|----|-|-----|-||-|||--||||----|||-----|||||-||||||||||||||||||  3    [O]    COG1651 Protein-disulfide isomerase
-|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-|||||||||||||  3    [J]    COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
-----------------|--------|---||||||||-|--|||||-||||-|||---|||||--  3    [K]    COG1737 Transcriptional regulators
---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||---  3    [R]    COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein
--||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||---  3    [P]    COG1840 ABC-type Fe3+ transport system, periplasmic component
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  3    [C]    COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3
-----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||--  3    [L]    COG1961 Site-specific recombinases, DNA invertase Pin homologs
---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||--  3    [I]    COG2030 Acyl dehydratase
--|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||--  3    [Q]    COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism
|-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||--  3    [I]    COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
----------------|-||-|---||||||----|||----|||||-||--|--|---|||||||  3    [T]    COG2200 FOG: EAL domain
----------------|---|-||||-----------|----|||||-||-|||||||||||||||  3    [T]    COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
-------------------|-|----||||-||||-|-----|||||--|-----|---|||||--  3    [S]    COG2261 Predicted membrane protein
--|---------------|-||--------------||----|||||-||---|||---|||||--  3    [R]    COG2334 Putative homoserine kinase type II (protein kinase fold)
----------------|--||-||||-||-------------||||||||||||||||||||||||  3    [M]    COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins
-----|--------------||----|||--|||||-|----|||||-|||----|---|||||--  3    [L]    COG2963 Transposase and inactivated derivatives
---------------------------------------------|----||-||-||-|-||--|  3    [M]    COG3306 Glycosyltransferase involved in LPS biosynthesis
--|---------------||-|----|||||-----||----------|------|---||||---  3    [M]    COG3409 Putative peptidoglycan-binding domain-containing protein
--||-|---------------|----------||---------|||-------------||||---  3    [L]    COG3436 Transposase and inactivated derivatives
------------------------------------------|||||---||-||----||||---  3    [M    U]    COG3468 Type V secretory pathway, adhesin AidA
---------------------|------------|-||-----------|-----|---|||||--  3    [R]    COG3545 Predicted esterase of the alpha/beta hydrolase fold
------------------------------------------------||---------|||||--  3    [S]    COG3672 Predicted periplasmic protein
|-|---------------|||------||||----|-----------------------|||||--  3    [T]    COG3920 Signal transduction histidine kinase
-------------------------------------|-|--||||----|----|---||||---  3    [G]    COG4214 ABC-type xylose transport system, permease component
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  3    [R]    COG4603 ABC-type uncharacterized transport system, permease component
---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||--  3    [M    R]    COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily
-----------------------------------------------------------||||--|  3    [R]    COG5342 Invasion protein B, involved in pathogenesis
||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||--  2    [H]    COG0001 Glutamate-1-semialdehyde aminotransferase
||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||--  2    [H]    COG0007 Uroporphyrinogen-III methylase
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  2    [F]    COG0015 Adenylosuccinate lyase
|||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||--  2    [E    H]    COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
--||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [E]    COG0031 Cysteine synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [D]    COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
-|||||||||-||||-|-||||----|||-||||---|----|||||-|-||-|||---|-|||--  2    [P]    COG0038 Chloride channel protein EriC
||||----||---|||||||||||||||||||||||||----|||||-||||||||||||||||||  2    [J]    COG0042 tRNA-dihydrouridine synthase
---------|---||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0050 GTPases - translation elongation factors
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  2    [H]    COG0054 Riboflavin synthase beta-chain
|||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---|||||||  2    [O]    COG0071 Molecular chaperone (small heat shock protein)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [R]    COG0073 EMAP domain
||||--||||--||----||-------||--|---|-|----||||--|-|---------|||---  2    [E]    COG0076 Glutamate decarboxylase and related PLP-dependent proteins
||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-|  2    [R]    COG0110 Acetyltransferase (isoleucine patch superfamily)
||||||||||||||||||||-|||||||||||||||||-|||||||||||||||||||||||||||  2    [E]    COG0112 Glycine/serine hydroxymethyltransferase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  2    [H]    COG0142 Geranylgeranyl pyrophosphate synthase
-|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||--  2    [J]    COG0144 tRNA and rRNA cytosine-C5-methylases
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [E    H]    COG0147 Anthranilate/para-aminobenzoate synthases component I
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  2    [G]    COG0149 Triosephosphate isomerase
--------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||--  2    [P]    COG0155 Sulfite reductase, beta subunit (hemoprotein)
-|--||||-----||||-||||||---|||----|-||----|||||-||||||||||||||||||  2    [H]    COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
--||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||---  2    [E]    COG0160 4-aminobutyrate aminotransferase and related aminotransferases
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  2    [F]    COG0167 Dihydroorotate dehydrogenase
-||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||--  2    [E    H]    COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
--||||--|----|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
-------------||||||||||||||||||||||||||||||||||-||||||||||||||||||  2    [I]    COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase
|-|||||||-|||||||||-|||||-||||||||||||-|||||||||||||||||||||||||||  2    [F]    COG0209 Ribonucleotide reductase, alpha subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0223 Methionyl-tRNA formyltransferase
||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--||||||  2    [G]    COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
--|----------||-||||||||||||||||||||||||||||||||||||||||||||||||||  2    [I    Q]    COG0236 Acyl carrier protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0242 N-formylmethionyl-tRNA deformylase
||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||--  2    [C]    COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing
--|--------|-|--||||||----|||||------|----|||||-||||||||||||||||||  2    [F    P]    COG0248 Exopolyphosphatase
|||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|----  2    [E    J]    COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D
------------|-|||-||||||--||||----|-|||||||||||||||||-||||||||||||  2    [E]    COG0260 Leucyl aminopeptidase
---|---------||---||----------------------||||||||||||||---|||||||  2    [T]    COG0271 Stress-induced morphogen (activity unknown)
--||-------------||-||--|||||-||||||||||||||||||||||||||-|||||||||  2    [C]    COG0280 Phosphotransacetylase
--|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--||||||||  2    [C]    COG0281 Malic enzyme
|--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||--  2    [P]    COG0288 Carbonic anhydrase
|||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||--  2    [H]    COG0303 Molybdopterin biosynthesis enzyme
||||----||--------||----------|----|----------|---|----------|----  2    [P]    COG0310 ABC-type Co2+ transport system, permease component
|||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||--  2    [R]    COG0312 Predicted Zn-dependent proteases and their inactivated homologs
--|----------||-|-||-|----||||----|-||----||||||||||||||---|||||||  2    [S]    COG0316 Uncharacterized conserved protein
----------------|-||||||---||-||||||||----|||||-||||||||||||||||||  2    [I]    COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  2    [U]    COG0341 Preprotein translocase subunit SecF
||||--||-|------|||||||||||||||---||||-|--|||||-||||||||||||||||||  2    [U]    COG0342 Preprotein translocase subunit SecD
|||||||||||||-||||||||||-||---||||||||----||||||||||||||||||||||||  2    [J]    COG0343 Queuine/archaeosine tRNA-ribosyltransferase
-------------|----||------|||||-----------|||||-|||||------|||||||  2    [J]    COG0349 Ribonuclease D
--|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||--  2    [H]    COG0352 Thiamine monophosphate synthase
|||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||---  2    [O    K]    COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase
|||||||||||||||-|-||-|||--|||||------|----|||||-||-|||||||||||||||  2    [H]    COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases
--||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||--  2    [R]    COG0384 Predicted epimerase, PhzC/PhzF homolog
--|----------|--|-||------|--|----|-||----|||||--|---|||---|||||--  2    [R]    COG0385 Predicted Na+-dependent transporter
|-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||--  2    [R]    COG0388 Predicted amidohydrolase
--||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||--  2    [L]    COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair
||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||---  2    [S]    COG0392 Predicted integral membrane protein
|-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||--  2    [T]    COG0394 Protein-tyrosine-phosphatase
||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||--  2    [M]    COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis
|||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||--  2    [F    R]    COG0402 Cytosine deaminase and related metal-dependent hydrolases
--|---||-----||-||||||||--|||||-----||----|||||-||-|||||||||||||||  2    [D]    COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
|||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||--  2    [R]    COG0433 Predicted ATPase
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [O]    COG0443 Molecular chaperone
|||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||--  2    [R]    COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases
||||||||||||||||||||||----|||||--|||||----|||||-||||||||||||||||||  2    [D]    COG0489 ATPases involved in chromosome partitioning
||||||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||  2    [O]    COG0492 Thioredoxin reductase
--|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--||||||||  2    [E    R]    COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||---  2    [F]    COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins
||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||--  2    [F]    COG0516 IMP dehydrogenase/GMP reductase
||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---|||||||  2    [E]    COG0531 Amino acid transporters
||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||--  2    [V]    COG0534 Na+-driven multidrug efflux pump
|||||||||-|||||||-||||||-|||||||||||||||||||||||||||||||||||||||||  2    [F    G    R]    COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
|------------||||||||||||||||||||||||||-|||||||-||||||||||||||||||  2    [O]    COG0542 ATPases with chaperone activity, ATP-binding subunit
---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||--  2    [C]    COG0554 Glycerol kinase
||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||--  2    [O]    COG0555 ABC-type sulfate transport system, permease component
-------------|||||||||||||||||||||||||||||||||||||||||||||||||||||  2    [J]    COG0564 Pseudouridylate synthases, 23S RNA-specific
||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||--  2    [V]    COG0577 ABC-type antimicrobial peptide transport system, permease component
---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||---  2    [C]    COG0578 Glycerol-3-phosphate dehydrogenase
----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||--  2    [S]    COG0586 Uncharacterized membrane-associated protein
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  2    [L]    COG0587 DNA polymerase III, alpha subunit
--|----------||||-||-|||--||||||-|||||----||||||||||||||---|||||||  2    [F    J]    COG0590 Cytosine/adenosine deaminases
|--------|------||||||---||||-|-----------|||||-||||||||||||||||-|  2    [O]    COG0606 Predicted ATPase with chaperone activity
-||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||--  2    [P]    COG0609 ABC-type Fe3+-siderophore transport system, permease component
-||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||--  2    [P]    COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component
|||||||||-|-|---|||||||||-||||-----|||----||||||||||||||||||||||||  2    [O    U]    COG0616 Periplasmic serine proteases (ClpP class)
----------------|-||-|||---|||-|--||||----|||-||-|||-|||||||||||||  2    [I]    COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH)
||||--|||-------||||||--|||||-||||||||----||||||||||||||||||||||||  2    [R]    COG0628 Predicted permease
|-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||--  2    [O]    COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
|||---||||------|||||------||-------||----|||||-||--||||||-|||||--  2    [G]    COG0662 Mannose-6-phosphate isomerase
||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-|||||||  2    [I]    COG0671 Membrane-associated phospholipid phosphatase
-||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||--  2    [R]    COG0693 Putative intracellular protease/amidase
|-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---|||||||  2    [O]    COG0695 Glutaredoxin and related proteins
|-|-||--|--|-|||--||||--|||||-||||-||-----|||||-||||||||||||||||||  2    [L]    COG0708 Exonuclease III
--|-------------|||||-----||||||||||||||||||||||||||||||||||||||||  2    [C]    COG0711 F0F1-type ATP synthase, subunit b
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  2    [O]    COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component
||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-|  2    [V]    COG0732 Restriction endonuclease S subunits
----------------||||||||------||||||||----||||||||||||||||||||||||  2    [I]    COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases
--|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||--  2    [F]    COG0775 Nucleoside phosphorylase
------------------||-|||--||||||---|||----|||||-||||||||||||||||--  2    [M]    COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
-----------------|||||||||----------------|||||-||||||||||||||||||  2    [R]    COG0795 Predicted permeases
----------------|-||----||----|-----------|||||-||||||||||||||||||  2    [M]    COG0797 Lipoproteins
-----------------|||----|-----||||--||----|||||-||||||||||-|||||--  2    [G]    COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  2    [E]    COG0804 Urea amidohydrolase (urease) alpha subunit
|-|------|------|-||||||------------------|||||-||||||||||||||||||  2    [U]    COG0811 Biopolymer transport proteins
|||------|-|----|--|||--------||||||||----|||||-||||-|||||||||----  2    [O]    COG0826 Collagenase and related proteases
--------------|---||-|----|-------|--||----||----||----|||-||||---  2    [O]    COG0829 Urease accessory protein UreH
--------------|---||-|----|||-----|--||----|||---||----|||-||||---  2    [O]    COG0830 Urease accessory protein UreF
--------------|---||-|----|||-----|-|||----|||---||----|||-||||---  2    [E]    COG0831 Urea amidohydrolase (urease) gamma subunit
--------------|---||-|----|||-----|-|||----|||---||----|||--|||---  2    [E]    COG0832 Urea amidohydrolase (urease) beta subunit
--||--|||-------||||-|--------|-----------|||||-||--|---||-|||||-|  2    [M]    COG0836 Mannose-1-phosphate guanylyltransferase
---|------||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  2    [C]    COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1
----------------|-||||||------------------|||||-||||||||||||||||||  2    [U]    COG0848 Biopolymer transport protein
------------------||-|----|||-|---||||----||||||||||||||||||||||||  2    [P]    COG0861 Membrane protein TerC, possibly involved in tellurium resistance
--||||-||-|||---|-||-|----|||-----||||----||||||||--||||||||||||||  2    [C    P]    COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
---|---------||-----||----|||-----|-||----||||||||--||||---|||||--  2    [C]    COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||--  2    [C    H    R]    COG1052 Lactate dehydrogenase and related dehydrogenases
-----------|-||---||------||||-------|----|||||--||--|||---|||||--  2    [C]    COG1062 Zn-dependent alcohol dehydrogenases, class III
--|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||---  2    [R]    COG1064 Zn-dependent alcohol dehydrogenases
--------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||---  2    [G]    COG1070 Sugar (pentulose and hexulose) kinases
-----|-------||-----------||||-|||-|||----|||||-|-||-------||||---  2    [H]    COG1072 Panthothenate kinase
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  2    [R]    COG1079 Uncharacterized ABC-type transport system, permease component
|||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||--  2    [G]    COG1082 Sugar phosphate isomerases/epimerases
|------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||--  2    [M]    COG1087 UDP-glucose 4-epimerase
|-|-----|-------|-||-------||-|-----------|||-|-||--|---||-|-|||--  2    [M]    COG1089 GDP-D-mannose dehydratase
-||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||--  2    [P    H]    COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
||||--|||||||----|||||--|-||||||||||||||||-||-|-|-|----|---|||----  2    [P]    COG1122 ABC-type cobalt transport system, ATPase component
||||----|||||---|||||||||||||-||||||||||||||||||||||||||||||||||||  2    [V]    COG1136 ABC-type antimicrobial peptide transport system, ATPase component
||||||-|||||-----|||-|----|||||-----------|||-|-||--|--|||||||||||  2    [C]    COG1146 Ferredoxin
----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||--  2    [K    E]    COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
--------|----------|||-----||-|||||||-----|||||--|-----|||-||||---  2    [E]    COG1174 ABC-type proline/glycine betaine transport systems, permease component
--|-------------||||||||||||||||||||||----|||||-||||||||||||||||||  2    [M]    COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes
||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-||  2    [I]    COG1183 Phosphatidylserine synthase
-------------||-|||||||||||||||||-||||----||||||||||||||||||||||||  2    [J]    COG1186 Protein chain release factor B
||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--||||||||||||||  2    [D]    COG1192 ATPases involved in chromosome partitioning
----------------||||||||||||||||||||||----||||||||||||||||||||||||  2    [L]    COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase
|||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||--  2    [M    J]    COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)
|-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-|  2    [M]    COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-||||||||||||||  2    [P]    COG1226 Kef-type K+ transport systems, predicted NAD-binding component
--|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||--  2    [M]    COG1247 Sortase and related acyltransferases
--||---------||-|||||||||||||-|||||||-||||||||||||||||||||||||||||  2    [R]    COG1253 Hemolysins and related proteins containing CBS domains
|-||--|||--------||||||-|-|---||||||||---------------------||||-||  2    [R]    COG1268 Uncharacterized conserved protein
--------------------|---|-|-----||||||-|--|||-|-||--------|||||---  2    [P]    COG1283 Na+/phosphate symporter
------------------|--|------------|||-----|||||-||||||||--|||||---  2    [S]    COG1289 Predicted membrane protein
----------------||----||||----|----|||----||||||||-----|||||||||--  2    [N    U]    COG1298 Flagellar biosynthesis pathway, component FlhA
|-||||--|-|||---|--|-|||---||-|-----|------------------------||---  2    [O]    COG1331 Highly conserved protein containing a thioredoxin domain
----------------||------||----|----|||----|||||-||-----|||||||||--  2    [N]    COG1344 Flagellin and related hook-associated proteins
----------------||------||----|----|||----|||||-||-----|||||||||--  2    [N]    COG1360 Flagellar motor protein
-------------------|||----|--||||||||||-|||||||-||||||||--||||||--  2    [P]    COG1393 Arsenate reductase and related proteins, glutaredoxin family
|-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||--  2    [R]    COG1409 Predicted phosphohydrolases
||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-|  2    [R]    COG1451 Predicted metal-dependent hydrolase
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  2    [P]    COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen
--||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||--  2    [R]    COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase
||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--||||||||||||||  2    [K]    COG1475 Predicted transcriptional regulators
--|-------------||--|||||-----||||-|------|||||-||||||||----||||--  2    [H]    COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis
---------------------|||------------||----|||||-||||||||||||||||||  2    [O]    COG1495 Disulfide bond formation protein DsbB
||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||---  2    [L]    COG1525 Micrococcal nuclease (thermonuclease) homologs
--||||||----|---||--||-----||------|||--------|--|-----|---|||||--  2    [R]    COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold
----------------||||----------------------|||-|-||-|||||--||||||--  2    [M]    COG1596 Periplasmic protein involved in polysaccharide export
--|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||--  2    [R]    COG1611 Predicted Rossmann fold nucleotide-binding protein
---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|----  2    [C]    COG1620 L-lactate permease
---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---|||||||  2    [C]    COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2
----------------|-|||---------------------|||||-||||||||||||||||--  2    [P]    COG1629 Outer membrane receptor proteins, mostly Fe transport
-------------|||-----|--|||---------------|||||-||||||||---|||||--  2    [L]    COG1643 HrpA-like helicases
-------------------|-||||||||||||||||||---|||||-||||||||||||||||||  2    [D]    COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins
-------------||||||-|---|--|||-|----||----|||-|-||--||||---|||||||  2    [R]    COG1752 Predicted esterase of the alpha-beta hydrolase superfamily
----------------||------||----|----|||----||||||||-----|||||||||--  2    [N    U]    COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein
--------|--|--------||----|||-|-|---||----|------||----|||-|||||-|  2    [I]    COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit
|-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---|||||||  2    [R]    COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
--||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||--  2    [C]    COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family
-----------------|--------|---||----||----|||||-------------||||--  2    [G]    COG1904 Glucuronate isomerase
---|||--|-|-|---||||||---|||||||||||||-|--|||||-|-||-------|||||--  2    [K    G]    COG1940 Transcriptional regulator/sugar kinase
----------------||||||-----||-||-|||||----|||||-||||||||--||||||||  2    [K]    COG1959 Predicted transcriptional regulator
--|-----|---------||-|----||||------||----------||---|||||||||||--  2    [C]    COG2010 Cytochrome c, mono- and diheme variants
--|---|||---||||--||-------||-|-----------------|-||---|----|||---  2    [O]    COG2020 Putative protein-S-isoprenylcysteine methyltransferase
--||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||--  2    [R]    COG2041 Sulfite oxidase and related enzymes
------------------|||-----|---------||----|||||-||-----|---|||||--  2    [E]    COG2066 Glutaminase
||-|||--||||------|||---------|----|----------|--|-----|---||||---  2    [H]    COG2073 Cobalamin biosynthesis protein CbiG
------------------||----------||||||||----|||||-||||---|---|||-|--  2    [R]    COG2081 Predicted flavoproteins
-||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||--  2    [U]    COG2095 Multiple antibiotic transporter
--|----------------------|-----||--||-----|||||--|-----|---||||---  2    [E]    COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components
----------------|---|-----------------------------------|||--|||||  2    [S]    COG2121 Uncharacterized protein conserved in bacteria
---|------|--||-|--|------|||-------||----|||||--|||||||--||||||--  2    [Q]    COG2132 Putative multicopper oxidases
||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||--  2    [C]    COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
|||-||||-||||----|---|----||||-|||||||----|---------|--|---|||||--  2    [R]    COG2151 Predicted metal-sulfur cluster biosynthetic enzyme
---------------------------||--|---|||----|||||-||-----|---|||||-|  2    [F]    COG2169 Adenosine deaminase
---|---------|||-|||-|--||----|---------|||||-|-||--|||-||||||||--  2    [O]    COG2214 DnaJ-class molecular chaperone
||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||--  2    [R]    COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
-|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|--  2    [R]    COG2252 Permeases
-------||----||--|-|||----||||||--||||----|||||-||||---|---|||||--  2    [I]    COG2267 Lysophospholipase
---|-------||-------||----|||--||---------|||||-|||----|---|||||--  2    [G]    COG2301 Citrate lyase beta subunit
---|||-----||--------|----||||----||||-----------|-----|---||||---  2    [R]    COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase
----||--|-|||-----||-|---------------------------|-----|-----|-|--  2    [R]    COG2366 Protein related to penicillin acylase
------------------||-|----|-------|--||----|||---||----|||-||||---  2    [O]    COG2371 Urease accessory protein UreE
---------------------|--------||||||||----|||||-|--|---|---||||---  2    [K]    COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
---|||---|||-----|---|------------|-------|||||-||--|--|--|||||---  2    [R]    COG2391 Predicted transporter component
||||--|||||||-|--|------------------------|||||-||--||||||||||||--  2    [O]    COG2518 Protein-L-isoaspartate carboxylmethyltransferase
---------||-------||-|----||||||--||||----|||||-||-----|---|||||--  2    [K]    COG2771 DNA-binding HTH domain-containing proteins
-|----||-|-|-----|---|---------|||||||----||||||||||-------|||||--  2    [J]    COG2813 16S RNA G1207 methylase RsmC
----||-----|-----|-|-|--------|-----------------|-----------|||---  2    [G]    COG2971 Predicted N-acetylglucosamine kinase
---|||--------------||----------|-|-||-------||-||-----|---|||||--  2    [E]    COG2986 Histidine ammonia-lyase
------------------------------------------|||||-|-||-------|||||--  2    [S]    COG2989 Uncharacterized protein conserved in bacteria
------------------|-----------------------|||||-||-||-||---|||||-|  2    [C]    COG3038 Cytochrome B561
------------------------------------------|||||-|-||-------|||||--  2    [S]    COG3108 Uncharacterized protein conserved in bacteria
--|----------------|------|----|--||------|||||-||---------|||||--  2    [R]    COG3153 Predicted acetyltransferase
------||---|---------|----||||-------------------|-----|---|||||--  2    [E    Q]    COG3191 L-aminopeptidase/D-esterase
----------------||||----------------------|||-|-||-||--|---|||||--  2    [M]    COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis
------------------||-------|-|------------|||||-||||-|||---|||||||  2    [C]    COG3288 NAD/NADP transhydrogenase alpha subunit
--|-----------------------|||--------|--------|-||-|---|---|||||--  2    [R]    COG3324 Predicted enzyme related to lactoylglutathione lyase
-------------||-----------||||-------------------|-----|---|||||||  2    [S]    COG3346 Uncharacterized conserved protein
----||-----|-|-------|------------|-|---------|--|-||--|---|||||--  2    [G]    COG3386 Gluconolactonase
------------------|||----------------|----|--||---||-------||||---  2    [S]    COG3395 Uncharacterized protein conserved in bacteria
-------------||--------------------------------------------|||||||  2    [C]    COG3474 Cytochrome c2
--------------------------|------------------|---|-----|---|||||||  2    [Q]    COG3485 Protocatechuate 3,4-dioxygenase beta subunit
-------------------|--------------------------|--|--|--|-----||---  2    [O]    COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases
-------------------------------||--|-------|||---||-|--------|----  2    [K]    COG3617 Prophage antirepressor
---------------------|-----------------------|---|---------|||||--  2    [E]    COG3741 N-formylglutamate amidohydrolase
---|-------------------------------------------------------|||||--  2    [S]    COG3743 Uncharacterized conserved protein
------------------------------||||--------|||-------|------||||---  2    [M]    COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase)
------------------------------|-----||---------------------|||||--  2    [M]    COG3773 Cell wall hydrolyses involved in spore germination
--------------------------|||------------------------------|||||--  2    [R]    COG3800 Predicted transcriptional regulator
---------------------|------------|-------|||||--|-|---|---||||---  2    [G]    COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||---  2    [R]    COG3845 ABC-type uncharacterized transport systems, ATPase components
----------------------------------------------|--|---------||||---  2    [S]    COG3921 Uncharacterized protein conserved in bacteria
----------------------------------------------|------||-----|||---  2    [R]    COG3926 Putative secretion activating protein
-------------------------------------------------|---------||||---  2    [E]    COG3931 Predicted N-formylglutamate amidohydrolase
-------------------------------------------------|---------||||---  2    [E]    COG3938 Proline racemase
------------------------------------------------|----------||||---  2    [S]    COG4103 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||||-||-----|---||||---  2    [R]    COG4172 ABC-type uncharacterized transport system, duplicated ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  2    [E]    COG4175 ABC-type proline/glycine betaine transport system, ATPase component
--|----------------------|-----||--||-----|||||--|-----|---||||---  2    [E]    COG4176 ABC-type proline/glycine betaine transport system, permease component
-------------|----||-------|||------------|||-----||-|-|---||||---  2    [R]    COG4178 ABC-type uncharacterized transport system, permease and ATPase components
------------------||-------||--------|----|||||-||--||||---|||||--  2    [P]    COG4208 ABC-type sulfate transport system, permease component
-------------------------------------------------|-----|----||----  2    [C]    COG4263 Nitrous oxide reductase
-------------------------------------------------|-----|---||||---  2    [R]    COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis
------------------------------------------------||-----|---|||||||  2    [S]    COG4395 Uncharacterized protein conserved in bacteria
---|----------------------||||-------------------|-----|---|||||||  2    [I]    COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit
----------------||------||----|----|||----||||||||-----|||||||||--  2    [N]    COG4786 Flagellar basal body rod protein
---|--|||--|-||--|--||----||||------||-----------|-----|---|||||||  2    [I]    COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
------------------------------------------|||-|--|--|--------|----  2    [T]    COG4943 Predicted signal transduction protein containing sensor and EAL domains
-------------------------------------------||----|-----|---|||||--  2    [K]    COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain
------------------------------|-----|----------------------||||---  2    [S]    COG4991 Uncharacterized protein with a bacterial SH3 domain homologue
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  2    [E]    COG4992 Ornithine/acetylornithine aminotransferase
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  2    [C]    COG5013 Nitrate reductase alpha subunit
--|-----------------|----------------|-----||||---||||||----|||---  2    [U    W]    COG5295 Autotransporter adhesin
--|--------------------------------------------------------||||---  2    [Q]    COG5310 Homospermidine synthase
-----------------------------------------------------------|||||--  2    [S]    COG5349 Uncharacterized protein conserved in bacteria
------------------------------------------------|------|-----|----  2    [S]    COG5591 Uncharacterized conserved protein
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||--  1    [E]    COG0002 Acetylglutamate semialdehyde dehydrogenase
|||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||--  1    [P]    COG0004 Ammonia permease
||||||||||||||||||||||||||||||||||||||||||||||||||||||||---|||||||  1    [J]    COG0009 Putative translation factor (SUA5)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0012 Predicted GTPase, probable translation factor
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0013 Alanyl-tRNA synthetase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1    [E]    COG0014 Gamma-glutamyl phosphate reductase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0016 Phenylalanyl-tRNA synthetase alpha subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0018 Arginyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1    [I]    COG0020 Undecaprenyl pyrophosphate synthase
-------------|||||||-||||-||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0021 Transketolase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1    [J]    COG0024 Methionine aminopeptidase
---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||--  1    [F]    COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0030 Dimethyladenosine transferase (rRNA methylation)
-------------||---|--|----|||-------------|||||-|----------|||||--  1    [G]    COG0033 Phosphoglucomutase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase
|--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||--  1    [F]    COG0035 Uracil phosphoribosyltransferase
-|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0036 Pentose-5-phosphate-3-epimerase
||||||--|||||||-||||||||-|||||||||||||-||||||||-|-|||--|--||||||||  1    [C]    COG0039 Malate/lactate dehydrogenases
||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||--  1    [E]    COG0040 ATP phosphoribosyltransferase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1    [H]    COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1    [C]    COG0045 Succinyl-CoA synthetase, beta subunit
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0048 Ribosomal protein S12
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0049 Ribosomal protein S7
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0051 Ribosomal protein S10
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0052 Ribosomal protein S2
||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--||||||||  1    [P]    COG0053 Predicted Co/Zn/Cd cation transporters
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0055 F0F1-type ATP synthase, beta subunit
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0056 F0F1-type ATP synthase, alpha subunit
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1    [G]    COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase
|||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E    H]    COG0059 Ketol-acid reductoisomerase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0060 Isoleucyl-tRNA synthetase
|||||||||||||||||||||---|||||||||||||||-||||||||||||||||||||||||||  1    [G]    COG0061 Predicted sugar kinase
|||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||--  1    [S]    COG0062 Uncharacterized conserved protein
||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||--  1    [G]    COG0063 Predicted sugar kinase
||||----||-||||-||||||||||||||||||||||||||-------|---|||||||||||||  1    [J]    COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)
||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0065 3-isopropylmalate dehydratase large subunit
|||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||--  1    [E]    COG0066 3-isopropylmalate dehydratase small subunit
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0067 Glutamate synthase domain 1
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0069 Glutamate synthase domain 2
|||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||--  1    [E]    COG0070 Glutamate synthase domain 3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0072 Phenylalanyl-tRNA synthetase beta subunit
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--||||||||  1    [C]    COG0074 Succinyl-CoA synthetase, alpha subunit
||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||--  1    [E]    COG0077 Prephenate dehydratase
|||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||--  1    [E]    COG0078 Ornithine carbamoyltransferase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0080 Ribosomal protein L11
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0081 Ribosomal protein L1
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0082 Chorismate synthase
|||---||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0084 Mg-dependent DNase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0087 Ribosomal protein L3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0088 Ribosomal protein L4
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0089 Ribosomal protein L23
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0090 Ribosomal protein L2
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0091 Ribosomal protein L22
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0092 Ribosomal protein S3
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0093 Ribosomal protein L14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0094 Ribosomal protein L5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0096 Ribosomal protein S8
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0097 Ribosomal protein L6P/L9E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0098 Ribosomal protein S5
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0099 Ribosomal protein S13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0100 Ribosomal protein S11
|||||||||||--||||||||||||||||||||||||||-||||||||||||||||||||||||||  1    [J]    COG0101 Pseudouridylate synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0102 Ribosomal protein L13
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0103 Ribosomal protein S9
||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||--  1    [F]    COG0104 Adenylosuccinate synthase
|||||||||||||||||-||-||||||||||--|||||----|||||-||||||||||||||||||  1    [F]    COG0105 Nucleoside diphosphate kinase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0107 Imidazoleglycerol-phosphate synthase
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase
---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---|||||||  1    [O]    COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor)
||||||--|||||||-|-||||||--|||||---||||----|||||-||-|||||||||||||||  1    [H]    COG0113 Delta-aminolevulinic acid dehydratase
--||------|||||---|--|||--||||----||||----|||||-||||||||||||||||||  1    [C]    COG0114 Fumarase
-------------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0117 Pyrimidine deaminase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0118 Glutamine amidotransferase
||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||--  1    [G]    COG0120 Ribose 5-phosphate isomerase
||--|-||--||-|----||-------||-------------|||||-||||-|||---||||---  1    [R]    COG0121 Predicted glutamine amidotransferase
|-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||--  1    [L]    COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
||||--|||||||||||-||-|------------|-||----------||---|||---|||||--  1    [B    Q]    COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0124 Histidyl-tRNA synthetase
||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||||||||||  1    [F]    COG0125 Thymidylate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0126 3-phosphoglycerate kinase
||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0127 Xanthosine triphosphate pyrophosphatase
||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0128 5-enolpyruvylshikimate-3-phosphate synthase
||||||||||||||||||||||||||||||||||||||||--||||||||||||||--||||||||  1    [J]    COG0130 Pseudouridine synthase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0131 Imidazoleglycerol-phosphate dehydratase
-|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||--  1    [H]    COG0132 Dethiobiotin synthetase
||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0133 Tryptophan synthase beta chain
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0134 Indole-3-glycerol phosphate synthase
||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||--  1    [E]    COG0135 Phosphoribosylanthranilate isomerase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1    [E]    COG0136 Aspartate-semialdehyde dehydrogenase
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0137 Argininosuccinate synthase
--||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||--  1    [F]    COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0139 Phosphoribosyl-AMP cyclohydrolase
||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0140 Phosphoribosyl-ATP pyrophosphohydrolase
||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0141 Histidinol dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0143 Methionyl-tRNA synthetase
-||--|--|||||||-|-||-------|-------|-|------------------||-|||||--  1    [E    Q]    COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit
-||--|---||||||-|-||-------|----------------------------||-|||||--  1    [E    Q]    COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||--  1    [G]    COG0148 Enolase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0150 Phosphoribosylaminoimidazole (AIR) synthetase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||--  1    [F]    COG0151 Phosphoribosylamine-glycine ligase
||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||||  1    [F]    COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase
---|---------||---||----------------------|||||-||||-||||||-||-|--  1    [G]    COG0158 Fructose-1,6-bisphosphatase
||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0159 Tryptophan synthase alpha chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0162 Tyrosyl-tRNA synthetase
|||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-|||  1    [H]    COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase
||||||||||||||||||||||||-|||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0164 Ribonuclease HII
||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||--  1    [E]    COG0165 Argininosuccinate lyase
-|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||--  1    [G]    COG0166 Glucose-6-phosphate isomerase
||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||----  1    [P]    COG0168 Trk-type K+ transport systems, membrane components
|||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||--  1    [H]    COG0171 NAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0172 Seryl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0173 Aspartyl-tRNA synthetase
-|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||--  1    [G]    COG0176 Transaldolase
||||||||||||||||||||||||||||||||||||||----||||||||||||||||||||||||  1    [L]    COG0177 Predicted EndoIII-related endonuclease
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0178 Excinuclease ATPase subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0180 Tryptophanyl-tRNA synthetase
||||||--|||||||-|-||||||--|||||---||||----||||||||-|||||||||||||||  1    [H]    COG0181 Porphobilinogen deaminase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0184 Ribosomal protein S15P/S13E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0185 Ribosomal protein S19
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0186 Ribosomal protein S17
-|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||--  1    [H    J]    COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
--||||----||-||-|||||||||||||||||||||||||||||||||||||-||||||||||||  1    [H]    COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
-------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||--  1    [G]    COG0191 Fructose/tagatose bisphosphate aldolase
-------------||-||||||--||||||||||||||||||||||||||||||||||||||||--  1    [H]    COG0192 S-adenosylmethionine synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0193 Peptidyl-tRNA hydrolase
-------------|||||||||||--||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0194 Guanylate kinase
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0195 Transcription elongation factor
-------------||-|||||||||-||||||||||||||||||||||||||||||||||||||--  1    [H]    COG0196 FAD synthase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0197 Ribosomal protein L16/L10E
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0198 Ribosomal protein L24
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0199 Ribosomal protein S14
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0200 Ribosomal protein L15
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0201 Preprotein translocase subunit SecY
||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0203 Ribosomal protein L17
||||||||||------||||||--||||||||||||||-|||||||||||||||||||||||||||  1    [D]    COG0206 Cell division GTPase
|||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||--  1    [F]    COG0207 Thymidylate synthase
---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-|||  1    [F]    COG0208 Ribonucleotide reductase, beta subunit
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0210 Superfamily I DNA and RNA helicases
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0211 Ribosomal protein L27
|--|-----||||||-|-|||||||-||||||-|||||--|||||||-||||||||||||||||||  1    [H]    COG0212 5-formyltetrahydrofolate cyclo-ligase
--|||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0215 Cysteinyl-tRNA synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0216 Protein chain release factor A
-------------||-|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [S]    COG0217 Uncharacterized conserved protein
-|||--||||---|--||--|---------||||||||||||||||||||||||||||||||||||  1    [R]    COG0218 Predicted GTPase
------------------||||||--|||||||||-|||||||||||-||||||||--||||||--  1    [J]    COG0219 Predicted rRNA methylase (SpoU class)
-------------||||||||||||-||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0220 Predicted S-adenosylmethionine-dependent methyltransferase
|-||||||-|-||||||-||||||--|||||----|-|||||||||||||||||||||||||||||  1    [C]    COG0221 Inorganic pyrophosphatase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0222 Ribosomal protein L7/L12
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0224 F0F1-type ATP synthase, gamma subunit
|-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||--  1    [O]    COG0225 Peptide methionine sulfoxide reductase
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1    [P]    COG0226 ABC-type phosphate transport system, periplasmic component
-------------||-|||||||||||||-|||||||||||||||||||||||||||||-||||||  1    [J]    COG0227 Ribosomal protein L28
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0228 Ribosomal protein S16
|-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||--  1    [O]    COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0230 Ribosomal protein L34
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)
------------------|--|----||||-----|------|||||-||||---|---|||||||  1    [F]    COG0232 dGTP triphosphohydrolase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0233 Ribosome recycling factor
--|----------||-||||||||||||||||||||||--||||||||||||||||||||||||||  1    [O]    COG0234 Co-chaperonin GroES (HSP10)
||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||||  1    [H]    COG0237 Dephospho-CoA kinase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0238 Ribosomal protein S18
|-------|----|||||||||||||||||||||||||||--|||||-||||||||||||||||||  1    [C]    COG0240 Glycerol-3-phosphate dehydrogenase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0244 Ribosomal protein L10
----------------|||||||||-|||||----|||--||||||||||||||||||||||||--  1    [I]    COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
-------------|---|--------|---||-||-||-||-||||||||-|---|---|||||--  1    [G]    COG0246 Mannitol-1-phosphate/altronate dehydrogenases
||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||---  1    [C]    COG0247 Fe-S oxidoreductase
--||-|-------|||||||||||||----|||-||||----||||||||||||||---|||||||  1    [L]    COG0249 Mismatch repair ATPase (MutS family)
|||||||||||||-|-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0250 Transcription antiterminator
||------||------|||||-||--|||||---||||----||||||||||||||||||||||||  1    [E]    COG0253 Diaminopimelate epimerase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0254 Ribosomal protein L31
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0255 Ribosomal protein L29
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0256 Ribosomal protein L18
-------------||-||||-||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0257 Ribosomal protein L36
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0258 5'-3' exonuclease (including N-terminal domain of PolI)
-------------||---||-|-----|||------------|||||-|||-||||---|||||--  1    [H]    COG0259 Pyridoxamine-phosphate oxidase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0261 Ribosomal protein L21
--|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-|  1    [H]    COG0262 Dihydrofolate reductase
--|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||--  1    [E]    COG0263 Glutamate 5-kinase
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0264 Translation elongation factor Ts
------------------||-|----||||-||||||||||||||||-||||||||---|||||-|  1    [L]    COG0266 Formamidopyrimidine-DNA glycosylase
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0267 Ribosomal protein L33
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0268 Ribosomal protein S20
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0272 NAD-dependent DNA ligase (contains BRCT domain type II)
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
----||-------||-|-||-|||--||||-|-|||||----|||||-||||||||||||||||||  1    [H]    COG0276 Protoheme ferro-lyase (ferrochelatase)
---|---------|||--||----------------------||||||||||||||---|||||||  1    [O]    COG0278 Glutaredoxin-related protein
--|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-||  1    [C]    COG0282 Acetate kinase
---------------||||||||||||||||||||||||||||||||-||||||||---|||||||  1    [F]    COG0283 Cytidylate kinase
|||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1    [F]    COG0284 Orotidine-5'-phosphate decarboxylase
---|||-------||-||||||--|-||||||||||||----||||||||||||||||||||||||  1    [H]    COG0285 Folylpolyglutamate synthase
||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-|  1    [V]    COG0286 Type I restriction-modification system methyltransferase subunit
||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||--  1    [E]    COG0287 Prephenate dehydrogenase
|||-----||------||||--||--|||-||-|||||----||||||||||||||||||||||||  1    [E]    COG0289 Dihydrodipicolinate reductase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0290 Translation initiation factor 3 (IF-3)
-------------|--||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0291 Ribosomal protein L35
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0292 Ribosomal protein L20
||||||--||---|||--------||----------------||||||||||||||---|||||||  1    [J]    COG0293 23S rRNA methylase
|||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1    [H]    COG0294 Dihydropteroate synthase and related enzymes
--||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||--  1    [F]    COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN
----------||-||-|-||||----||||||||-|||----|||||-|||||--|||||||||||  1    [H]    COG0302 GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0305 Replicative DNA helicase
---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0307 Riboflavin synthase alpha chain
--|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||--  1    [E]    COG0308 Aminopeptidase N
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0313 Predicted methyltransferases
|||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||--  1    [H]    COG0314 Molybdopterin converting factor, large subunit
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1    [H]    COG0315 Molybdenum cofactor biosynthesis enzyme
----------------||||||---||||||||||||||-|||||||-||||||||||||||||-|  1    [T    K]    COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases
|-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--||||||||  1    [I    Q]    COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0319 Predicted metal-dependent hydrolase
---|------|||||-|-||-|||--||||----|-||----||||||||||||||---|||||||  1    [H]    COG0320 Lipoate synthase
----------|--||---||-|----||||------------||||||||||||||---|||||||  1    [H]    COG0321 Lipoate-protein ligase B
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0322 Nuclease subunit of the excinuclease complex
--||---------|||||||||||||----||||||||----||||||||||||||---|||||||  1    [L]    COG0323 DNA mismatch repair enzyme (predicted ATPase)
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1    [J]    COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase
--|----------||-||||||----||||||||||||----||||||||||||||||||||||--  1    [R]    COG0325 Predicted enzyme with a TIM-barrel fold
---|------|--||---||-|--|-||||----||||----|||||-||||||||||||||||||  1    [L]    COG0328 Ribonuclease HI
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||||  1    [I]    COG0331 (acyl-carrier-protein) S-malonyltransferase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [J]    COG0333 Ribosomal protein L32
--|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|--  1    [E]    COG0334 Glutamate dehydrogenase/leucine dehydrogenase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0335 Ribosomal protein L19
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0336 tRNA-(guanine-N1)-methyltransferase
----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0337 3-dehydroquinate synthetase
-------------||---||-|----|---------------|||||-||||||||---|||||--  1    [E]    COG0339 Zn-dependent oligopeptidases
||||--|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||||  1    [H]    COG0340 Biotin-(acetyl-CoA carboxylase) ligase
----------------||||||--------|||||||||||||||||-||||-|||||||||||--  1    [S]    COG0344 Predicted membrane protein
|-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||--  1    [E]    COG0345 Pyrroline-5-carboxylate reductase
|||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||--  1    [E]    COG0347 Nitrogen regulatory protein PII
|||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||--  1    [H]    COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
----------------|-|||||||-||||||||||||||--|||||-||||||||||||||||||  1    [L]    COG0353 Recombinational DNA repair protein (RecF pathway)
-------------||-|-||-|----||||------------||||||||||||||---|||||||  1    [R]    COG0354 Predicted aminomethyltransferase related to GcvT
--|----------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)
--|----------|--|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0356 F0F1-type ATP synthase, subunit a
----------------||||||--|||||||||||||||||||||||-||||||||||||||||||  1    [M]    COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0358 DNA primase (bacterial type)
--------------|-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0359 Ribosomal protein L9
-------------||-|||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0360 Ribosomal protein S6
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0361 Translation initiation factor 1 (IF-1)
-------------|||-|||--||||||||-|-||||-----|||||||-||-||----||||---  1    [G]    COG0362 6-phosphogluconate dehydrogenase
-------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||--  1    [G]    COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase
-------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||--  1    [G]    COG0364 Glucose-6-phosphate 1-dehydrogenase
|||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||---  1    [H]    COG0368 Cobalamin-5-phosphate synthase
-------------|||--||--||----------|-||----||||||||--|||----|-|-|--  1    [P]    COG0369 Sulfite reductase, alpha subunit (flavoprotein)
|-||||--|-|||||-||||-|----||||-|--||||----|||||-||-|||||||||||||||  1    [C]    COG0372 Citrate synthase
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases
|||||||||||||----|||-||||-||||||||||||----|||||-----|------|||||--  1    [O]    COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
-------------||---||-|||-------|--||||----|||----|--|------||||-||  1    [R]    COG0400 Predicted esterase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1    [E]    COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain
--|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||--  1    [G]    COG0406 Fructose-2,6-bisphosphatase
--|-||-------||-|-||-|||--||||----||||----|||||-||-|||||||||||||||  1    [H]    COG0407 Uroporphyrinogen-III decarboxylase
-------------||---||----------------------|||||-||--|--|---|||||||  1    [H]    COG0408 Coproporphyrinogen III oxidase
---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||--  1    [H]    COG0413 Ketopantoate hydroxymethyltransferase
-------------||-||||-|----|||||---||||----||||||||--||||||||||||--  1    [H]    COG0414 Panthothenate synthetase
----------------||||||||------|||||||||||||||||-||-|-|||||||||||--  1    [I]    COG0416 Fatty acid/phospholipid biosynthesis enzyme
||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||--  1    [O]    COG0425 Predicted redox protein, regulator of disulfide bond formation
---|----|----||---|-|-----|---------------|||||--|---------|-|-|--  1    [C]    COG0427 Acetyl-CoA hydrolase
---|---------||---||------|---------------|||-|-||---------||||---  1    [O]    COG0435 Predicted glutathione S-transferase
|||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0439 Biotin carboxylase
|||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||--  1    [E]    COG0440 Acetolactate synthase, small (regulatory) subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0441 Threonyl-tRNA synthetase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0442 Prolyl-tRNA synthetase
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [D]    COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division
||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||--  1    [M]    COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
|||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--|||||||||||  1    [O]    COG0450 Peroxiredoxin
|||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||--  1    [H]    COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase
||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||--  1    [R]    COG0456 Acetyltransferases
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1    [E    F]    COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
||||||||||||||||||||||||||||||||||||||--||||||||||||||||||||||||||  1    [O]    COG0459 Chaperonin GroEL (HSP60 family)
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0460 Homoserine dehydrogenase
|||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||--  1    [F]    COG0461 Orotate phosphoribosyltransferase
|||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-|  1    [F    E]    COG0462 Phosphoribosylpyrophosphate synthetase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0465 ATP-dependent Zn proteases
--|----------||-||--||||||----|-----||||||||||||||||||||||||||||||  1    [O]    COG0466 ATP-dependent Lon protease, bacterial type
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0468 RecA/RadA recombinase
-|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||--  1    [G]    COG0469 Pyruvate kinase
|||||||||||||||||||||||||-||||-|||||||||||||||||||||||||||||||||||  1    [L]    COG0470 ATPase involved in DNA replication
||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||----  1    [P]    COG0471 Di- and tricarboxylate transporters
|||---||||||-||-||||-|----||||||--||||----||||||||||||||--||||||||  1    [C    E]    COG0473 Isocitrate/isopropylmalate dehydrogenase
|||-|--------||||-|||-----||||||||-||||||||||||--|----------|||---  1    [P]    COG0474 Cation transport ATPase
|||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-||||||||||||||  1    [P]    COG0475 Kef-type K+ transport systems, membrane components
|-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||--  1    [H]    COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||||||||||||  1    [C]    COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0480 Translation elongation factors (GTPases)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0481 Membrane GTPase LepA
-------------||-||||||||-|||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
|-||||-------|||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
-------------||-||||||||||----||||||||||||||||||||||||||||||||||||  1    [R]    COG0486 Predicted GTPase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0495 Leucyl-tRNA synthetase
||||----|||-||--||||-||||-----------------|||||-||||||||||||||||--  1    [R]    COG0496 Predicted acid phosphatase
----------------|-||||--|-||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0497 ATPase involved in DNA repair
|||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0498 Threonine synthase
|||||||||||||||-||||------||||-------------------|--|--|---|||||--  1    [H]    COG0499 S-adenosylhomocysteine hydrolase
|||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||--  1    [O]    COG0501 Zn-dependent protease with chaperone function
|||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||--  1    [H]    COG0502 Biotin synthase and related enzymes
||||||||||||||||||||-|||||||||||||||||||--||||||||||||||||||||||||  1    [F]    COG0504 CTP synthase (UTP-ammonia lyase)
||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||--  1    [E    F]    COG0505 Carbamoylphosphate synthase small subunit
---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||--  1    [E]    COG0506 Proline dehydrogenase
-|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||---  1    [L]    COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member
---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||--  1    [E]    COG0509 Glycine cleavage system H protein (lipoate-binding)
|||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||--  1    [I]    COG0511 Biotin carboxyl carrier protein
||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||--  1    [E    H]    COG0512 Anthranilate/para-aminobenzoate synthases component II
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1    [F]    COG0518 GMP synthase - Glutamine amidotransferase domain
|||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||--  1    [F]    COG0519 GMP synthase, PP-ATPase domain/subunit
|-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||--  1    [E]    COG0520 Selenocysteine lyase
|||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||--  1    [H]    COG0521 Molybdopterin biosynthesis enzymes
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0522 Ribosomal protein S4 and related proteins
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0525 Valyl-tRNA synthetase
|||||-|||||||||-||||-|||--||||||-|||||----||||||||||||||||||||||||  1    [E]    COG0527 Aspartokinases
|||||||||||||---||||||||||||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0528 Uridylate kinase
-------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||--  1    [P]    COG0529 Adenylylsulfate kinase and related kinases
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0532 Translation initiation factor 2 (IF-2; GTPase)
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0533 Metal-dependent proteases with possible chaperone activity
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG0536 Predicted GTPase
---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||--  1    [C]    COG0538 Isocitrate dehydrogenases
-------------||-||||||||||||||||||||||-|--||||||||||||||||||||||||  1    [J]    COG0539 Ribosomal protein S1
|||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||--  1    [F]    COG0540 Aspartate carbamoyltransferase, catalytic chain
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0541 Signal recognition particle GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)
||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||--  1    [E]    COG0547 Anthranilate phosphoribosyltransferase
|||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-|  1    [E]    COG0548 Acetylglutamate kinase
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0550 Topoisomerase IA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0552 Signal recognition particle GTPase
|-||------------|||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0556 Helicase subunit of the DNA excision repair complex
---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||--  1    [K]    COG0557 Exoribonuclease R
|-|||||||-|||||||||||-|||||||||||||||||||||||||-||||||||||||||||||  1    [I]    COG0558 Phosphatidylglycerophosphate synthase
|||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||--  1    [E]    COG0560 Phosphoserine phosphatase
--||--|||----|||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [F]    COG0563 Adenylate kinase and related kinases
||||||--||-||-----||-|--------------------|||||-||||||||---|||||-|  1    [J]    COG0565 rRNA methylase
-------------||------|||--||||----|-||----||||||||||||||---|||||||  1    [C]    COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes
||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||----  1    [P]    COG0569 K+ transport systems, NAD-binding component
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0571 dsRNA-specific ribonuclease
||||---||||||---||||-|---||||||||||||||-|||||||-|-|||--|--||||||--  1    [P]    COG0573 ABC-type phosphate transport system, permease component
|||||||||||||---||||||--|-|||||--|-||-----|||||-||--||||||||||||||  1    [G]    COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
|||||||||||||||||||||||||||||||||||||||||||||||-||||||||||||||||||  1    [I]    COG0575 CDP-diglyceride synthetase
|-||||-------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0576 Molecular chaperone GrpE (heat shock protein)
----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||--  1    [R]    COG0579 Predicted dehydrogenase
|-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||--  1    [G]    COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1    [P]    COG0581 ABC-type phosphate transport system, permease component
---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||--  1    [C]    COG0584 Glycerophosphoryl diester phosphodiesterase
--|----------||-----|-||||||||||||||------||||||--||||||----||||--  1    [G]    COG0588 Phosphoglycerate mutase 1
|-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-||  1    [E    R]    COG0591 Na+/proline symporter
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
-----------------||||||||||||||||||||||||||||||||||||||||||-||||||  1    [J]    COG0594 RNase P protein component
||||--||-|-------|||||----||||||||||||||||--------------||||||||||  1    [R]    COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M    U]    COG0597 Lipoprotein signal peptidase
-||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-|  1    [P]    COG0598 Mg2+ and Co2+ transporters
|||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||--  1    [S]    COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit
||||||||||||----|-|||---------||||||||----|||||-||||||||||||||||||  1    [O]    COG0602 Organic radical activating enzymes
|||||||||||||---|-||----------|---|-||----|||||-||||||||||||||||||  1    [R]    COG0603 Predicted PP-loop superfamily ATPase
|-||||----|||||||-||-|||-|||||||||||||----||||||||||||||||||||||||  1    [P]    COG0605 Superoxide dismutase
||||||||||||----|||||||||||---||||||||----|||||-||||||||||||||||||  1    [L]    COG0608 Single-stranded DNA-specific exonuclease
||||---||----------|-----------||-||--|||-------||||||--|||-||-|-|  1    [V]    COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
-------------|||||||||||||||||||||||||----||||||||||||||||||||||||  1    [J]    COG0617 tRNA nucleotidyltransferase/poly(A) polymerase
||||--||||-||----|||||----||||||||||||||||-||-|---|--------|||----  1    [P]    COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
-------------|----||------||||-|||||------|||||--|||-|||---|||||--  1    [R]    COG0627 Predicted esterase
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG0629 Single-stranded DNA-binding protein
-||||||||-|||---------------------------------------|---||-|||||||  1    [N    U]    COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG0632 Holliday junction resolvasome, DNA-binding subunit
---|---------||||-||-|||--|---------------||||||||||-|||---|||||||  1    [C]    COG0633 Ferredoxin
----------------||--||----||||||-|||||||||||||||||||||||---|||||--  1    [F]    COG0634 Hypoxanthine-guanine phosphoribosyltransferase
||||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K
|||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||--  1    [C]    COG0644 Dehydrogenases (flavoproteins)
-----------------|||||----|||||---||||----|||||-||-----|---|||||--  1    [E]    COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain
---|--|||--||||-||--|-----|||--|||||||----|||||--|--------||||||||  1    [G]    COG0647 Predicted sugar phosphatases of the HAD superfamily
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7
||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--||  1    [C    P]    COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase)
|||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-|  1    [R]    COG0655 Multimeric flavodoxin WrbA
---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||--  1    [R]    COG0656 Aldo/keto reductases, related to diketogulonate reductase
----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-|  1    [R]    COG0658 Predicted membrane metal-binding protein
|-||||-----|-||---||-------||||------|----|||||-||-|||||---|||||||  1    [R]    COG0661 Predicted unusual protein kinase
|||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--||||||||  1    [R]    COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily
|||||||||||||-||||||||--|||||-||||||||----||||||||--||||||||||||||  1    [M]    COG0668 Small-conductance mechanosensitive channel
----------------||||||--||||||||||||||-|--||||||||||||||||||||||--  1    [H]    COG0669 Phosphopantetheine adenylyltransferase
-------------||---||||||-|----|||||||--|--|||||-||||-|||||||||||||  1    [R]    COG0670 Integral membrane protein, interacts with FtsH
--------|---|||--||||---|---------|||-----||||---|-|-||---|--|--||  1    [P]    COG0672 High-affinity Fe2+/Pb2+ permease
-------------||---||-------------------------|--|-||-|||---|||||--  1    [O]    COG0678 Peroxiredoxin
||-------|---||-|||||-----|---||--||||----||||--||-||--|--||||||||  1    [R]    COG0679 Predicted permeases
||||||||||||||||||||||||||||||||||||||-|--||||||||||||||||||||||||  1    [U]    COG0681 Signal peptidase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [M]    COG0682 Prolipoprotein diacylglyceryltransferase
--|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||--  1    [E]    COG0685 5,10-methylenetetrahydrofolate reductase
||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-||  1    [I]    COG0688 Phosphatidylserine decarboxylase
|---|||||||||||||--|||----||||-----|||----|||||-||||||||---|||||||  1    [J]    COG0689 RNase PH
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0690 Preprotein translocase subunit SecE
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG0691 tmRNA-binding protein
---|----|----||---||--||----------||||----|||||||||||---||||||||||  1    [O]    COG0694 Thioredoxin-like proteins and domains
----------------|||-|-----|||||-|||||||||||--||----|----|||-|||-||  1    [G]    COG0698 Ribose 5-phosphate isomerase RpiB
---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||--  1    [M    G]    COG0702 Predicted nucleoside-diphosphate-sugar epimerases
--|----------||-||||||||--||||||||||||----||||||||||||||||||||||--  1    [E]    COG0703 Shikimate kinase
|||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||--  1    [P]    COG0704 Phosphate uptake regulator
-||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||--  1    [R]    COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid)
-------------||-||||||||||||||||||||||||||||||||||||||||||||||||||  1    [U]    COG0706 Preprotein translocase subunit YidC
--|------|-|----||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
-------------||-|||||-----||||||||||||||||||||||||||||||||||||||||  1    [C]    COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)
--||||------|---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)
|||||||||||||---|-||--||--|||||------|----||||||-|||||||||||||||||  1    [F]    COG0717 Deoxycytidine deaminase
-----------------|||||||-|||||||||||||||||||||||||||||||||||||||||  1    [S]    COG0718 Uncharacterized protein conserved in bacteria
||||||||||||----||||----------|---|-||----|||||-||||||||||||||||||  1    [H]    COG0720 6-pyruvoyl-tetrahydropterin synthase
||||----||-||---||||||||||||||||||||||--||-------|---|||||||||||||  1    [J]    COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit
--||||----|||||-|-||-|----|||||-----||----------||--||||||||||||||  1    [C]    COG0723 Rieske Fe-S protein
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1    [P]    COG0725 ABC-type molybdate transport system, periplasmic component
----------------|||||||||||||||-----------||||||||||||||||||||||||  1    [R]    COG0728 Uncharacterized membrane protein, putative virulence factor
----------------|---|---------------------|||||-||||||||---|||||--  1    [M]    COG0729 Outer membrane protein
-------------||-||--|||||||||||||||||||||||||||||----|||||||||||||  1    [I]    COG0736 Phosphopantetheinyl transferase (holo-ACP synthase)
-------------|----------------------|-----|||-|---|-|||-|||--|-|--  1    [G]    COG0738 Fucose permease
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [O    U]    COG0740 Protease subunit of ATP-dependent Clp proteases
-----------------|||||||||||||||||||||-|--||||||||||||||||||||||||  1    [L]    COG0742 N6-adenine-specific methylase
|||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||--  1    [H]    COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A
-------------|--||||||||||||||||||||||----|||||-||||||||||||||||||  1    [L]    COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains
|||||||||||||---||||||||||||||||||||||----|||||-||||||||||||||||||  1    [M]    COG0750 Predicted membrane-associated Zn-dependent proteases 1
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1    [J]    COG0751 Glycyl-tRNA synthetase, beta subunit
----------------|||||-||-------|||-|||----||||||||||||||||||||||||  1    [J]    COG0752 Glycyl-tRNA synthetase, alpha subunit
-------------||------|----|-------||||----|||||-||||-||||||||||---  1    [P]    COG0753 Catalase
--|-----|-|-|---|-||-|----||||----|-||----|||||-||||||||||||||||||  1    [O]    COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
-------------||||---|-|||-||||||||-||-----||||||-|||||||||-|||||||  1    [F]    COG0756 dUTPase
-----------------|||||----|||||-----||-------|-||||||--|||||||||--  1    [E]    COG0757 3-dehydroquinate dehydratase II
----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-|  1    [L    U]    COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake
----------------||||||||||-||-||||||||----|---|-|||||||||||||||||-  1    [S]    COG0759 Uncharacterized conserved protein
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1    [I    M]    COG0761 Penicillin tolerance protein
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG0763 Lipid A disaccharide synthetase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG0767 ABC-type transport system involved in resistance to organic solvents, permease component
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0768 Cell division protein FtsI/penicillin-binding protein 2
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0769 UDP-N-acetylmuramyl tripeptide synthase
|||------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0770 UDP-N-acetylmuramyl pentapeptide synthase
|--------|------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [D]    COG0772 Bacterial cell division membrane protein
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0773 UDP-N-acetylmuramate-alanine ligase
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0777 Acetyl-CoA carboxylase beta subunit
----------------||||||--|||||-||||||||----|||||-||||||||||||||||||  1    [S]    COG0779 Uncharacterized protein conserved in bacteria
----------|-|---||||-------------||-||----|||||-||||||||||||||||||  1    [R]    COG0780 Enzyme related to GTP cyclohydrolase I
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [K]    COG0781 Transcription termination factor
---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-|||  1    [P]    COG0783 DNA-binding ferritin-like protein (oxidative damage protectant)
|-|---|||-|-|---||||||--|-||||--||--||------------||----||-||||---  1    [O]    COG0785 Cytochrome c biogenesis protein
--------------|-|-||||--||||||||||||||----|||||-||||||||||||||||||  1    [M]    COG0787 Alanine racemase
---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|--  1    [F]    COG0788 Formyltetrahydrofolate hydrolase
----------------||||||--|-|||||-----------|||||-||||||||||||||||--  1    [L]    COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase
----||----||----||||||||||----|---||||----|||||-||||||||||||||||||  1    [M]    COG0793 Periplasmic protease
|||---|||||||---|---|-||------|---|||-----|||||-||||||||||||||||||  1    [M]    COG0794 Predicted sugar phosphate isomerase involved in capsule formation
----------------|-||||--||||||||||||||----||||||||||-|||||||||||--  1    [M]    COG0796 Glutamate racemase
----------------||||-|||||||||-|||||||----|||||-||||||||||||||||||  1    [S]    COG0799 Uncharacterized homolog of plant Iojap protein
-------------||-||||||||--||||||||||||----|||||-||||||||||||||||-|  1    [H]    COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase
----------------||||||||||||||||||||||-|--|||||-||||||||||||||||||  1    [R]    COG0802 Predicted ATPase or kinase
--||||--|-|||---|-||-|----||||----||||----|||||-||||||||||||||||||  1    [U]    COG0805 Sec-independent protein secretion pathway component TatC
----------------||||||--||||||||||||||----||||||||||||||||||||||||  1    [J]    COG0806 RimM protein, required for 16S rRNA processing
----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG0807 GTP cyclohydrolase II
----------------||||||---|----||||||||----||||||||||||||||||||||||  1    [J]    COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)
----------------|--||---------------------|||||-||||||||||||||||--  1    [M]    COG0810 Periplasmic protein TonB, links inner and outer membranes
----------------||||||||||||||||||||||----||||||||||||||||||||||||  1    [M]    COG0812 UDP-N-acetylmuramate dehydrogenase
----------------||||-|||||||||------------|||||-||||-|||||||||||||  1    [M]    COG0815 Apolipoprotein N-acyltransferase
----------------||||||||--|||||||-||||||||||||||||||||||||||||||||  1    [L]    COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis)
-----------------||||||||-||||------------|||||-||||||||||||||||||  1    [L]    COG0817 Holliday junction resolvasome, endonuclease subunit
-----------------|||-|--------||||||||----|||||-|||||||||||||||---  1    [M]    COG0818 Diacylglycerol kinase
----||||--|||||----|------|----|-|||||------------||----|||--|----  1    [K]    COG0819 Putative transcription activator
----------------||||||--|-|||-|||||||||---||||||||||||||||||||||--  1    [R]    COG0820 Predicted Fe-S-cluster redox enzyme
----------------|||||||||-|||||-----||----||||||||||||||||||||||--  1    [I]    COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
--||----|----|||||-||-||||||||||||||||||||||||||||||-|||||||||||||  1    [C]    COG0822 NifU homolog involved in Fe-S cluster formation
--|-----|---------||--||------------------|||||-|||||--|||||||||||  1    [U]    COG0823 Periplasmic component of the Tol biopolymer transport system
|-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||--  1    [R]    COG0824 Predicted thioesterase
----------------|-||||||--|||-||||||||----|||||-||||||||||||||||--  1    [I]    COG0825 Acetyl-CoA carboxylase alpha subunit
----------------|-||--||||----|||||||||-||||||||||||||||||||||||||  1    [J]    COG0828 Ribosomal protein S21
------------------||----------------------|||||--|--||||||-|||||--  1    [G]    COG0837 Glucokinase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A)
--||||--|--||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J)
---------|------||--||--||----||||||||----||||||||||||||||||||||||  1    [D]    COG0849 Actin-like ATPase involved in cell division
----------------||||||--------|----|||----||||||||-|||||||-||||---  1    [D]    COG0850 Septum formation inhibitor
------------------||||--------------------||||||||--||||||-||||---  1    [D]    COG0851 Septum formation topological specificity factor
--|||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit
----------------|-||----------------------|||||-||--||||||||||||--  1    [H]    COG0854 Pyridoxal phosphate biosynthesis protein
--|---------------||-|-----||||------|----|||||-||--||||||||||||--  1    [P]    COG0855 Polyphosphate kinase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG0858 Ribosome-binding factor A
----------------|-|||||||||||||---||||----||||||||||||||||||||||--  1    [M]    COG0860 N-acetylmuramoyl-L-alanine amidase
-|-||||----------|-|||----------|--|-|----|||||-|-|-||-|||-|||||--  1    [L]    COG0863 DNA modification methylase
||||--|||||||-----------------|----|||----|||-|---------||---|-|--  1    [K]    COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain
|||-----||-----------|---|----|----|||----|||--------------||||---  1    [F]    COG1001 Adenine deaminase
---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||--  1    [E]    COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain
-|||---||--|----|-||------|||---|---||----|||||-||-||--|--||||||||  1    [M]    COG1004 Predicted UDP-glucose 6-dehydrogenase
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H)
||||--||---------|||-|----|-------||||----------||---------|||--||  1    [P]    COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit
--||||--|-|||---|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N)
--||||----------|-||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M)
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG1010 Precorrin-3B methylase
-------------||----|------||||-||||||-----|||||-||-----|--||-||---  1    [Q]    COG1020 Non-ribosomal peptide synthetase modules and related proteins
---------------------------||-------|-----|||||-||-----------|----  1    [Q]    COG1021 Peptide arylation enzymes
----||-----------|-|------|---|-----||----|||||-||||-||-||||-|----  1    [E]    COG1027 Aspartate ammonia-lyase
----------------||||-|-----||-|-----------||||||-|--||||||||||||||  1    [C]    COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
-------------||-----------|||-||--||||---------------------||||---  1    [C]    COG1038 Pyruvate carboxylase
----------------||||||--||-||-||||||||----|||||-||||||||||||||||-|  1    [R]    COG1040 Predicted amidophosphoribosyltransferases
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase
----------------|-|||-||------------------|||||-||||||||||||||||||  1    [M]    COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase
--||----------|--|||------||||||||||||----||||||||||-|||||||||||--  1    [E]    COG1045 Serine acetyltransferase
--||||----|||||-|----|----||||||--|||-----|||||-||--||||---|||||||  1    [C]    COG1048 Aconitase A
|||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-|  1    [F]    COG1051 ADP-ribose pyrophosphatase
||-|||--|||||||-||||||||--||||||--||||----|||||-||||||||||||||||||  1    [C]    COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
------------------||-|||--|----||||||-----||||||||--|--|---|||||||  1    [R]    COG1054 Predicted sulfurtransferase
-------------||-|||||---||||||||||||||||||||||||||--||||||||||||--  1    [H]    COG1057 Nicotinic acid mononucleotide adenylyltransferase
---||||||-||||---|||||-----||||-||||||----|||||-|----|||---|||||--  1    [R]    COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
----------------|||||||||-|||-|||-||||----|||||-||||||||||||||||||  1    [O]    COG1066 Predicted ATP-dependent serine protease
-------------|--------------------|-||----|||||------------||||---  1    [C]    COG1069 Ribulose kinase
--||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||--  1    [R]    COG1073 Hydrolases of the alpha/beta superfamily
--------------------|-||||-||-||||||||----||||||||||||||||||||||||  1    [L]    COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
-------------|||--|-----------------------||||||||||-|||--||||||||  1    [O]    COG1076 DnaJ-domain-containing proteins 1
-|---------------|--|---|-|---|--||-||----------||-||||||||-||||||  1    [M    G]    COG1086 Predicted nucleoside-diphosphate sugar epimerases
-|----||-|--|---||--||||-------||||||-----||||||||||||||---||||---  1    [R]    COG1092 Predicted SAM-dependent methyltransferases
--------------------|-----|-----||--------------||-----|---||||-||  1    [R]    COG1101 ABC-type uncharacterized transport system, ATPase component
--|-----|----||||||||||||-||||||||||||----||||||||||-|||||||||||||  1    [E]    COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes
|-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-||  1    [P]    COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components
--------------------------|||||||-||||----|||||--|---------|-|----  1    [E]    COG1113 Gamma-aminobutyrate permease and related permeases
--|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||----  1    [E]    COG1115 Na+/alanine symporter
||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||--  1    [P]    COG1117 ABC-type phosphate transport system, ATPase component
------------------||-------||--------|----|||||-||--||||||||||||--  1    [P]    COG1118 ABC-type sulfate/molybdate transport systems, ATPase component
|-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-||  1    [P]    COG1121 ABC-type Mn/Zn transport systems, ATPase component
--|--|--------------|-||--------|-|--|||--|||||------------||||---  1    [E    P]    COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
--------|----------|||-----||-|||||||-----|||||--|------||-||||---  1    [E]    COG1125 ABC-type proline/glycine betaine transport systems, ATPase components
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component
------------------------------------------|||-|-----------|||||---  1    [I]    COG1133 ABC-type long-chain fatty acid transport system, fused permease and ATPase components
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1    [G    M]    COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component
------------------||||-||-|---||||||||----|||||-||||||||||||||||--  1    [P]    COG1135 ABC-type metal ion transport system, ATPase component
----------------||||||||||----------------|||||-||||||||||||||||||  1    [R]    COG1137 ABC-type (unclassified) transport system, ATPase component
--|-----|-|-|--------|--------------------|||||-|||||------|||||||  1    [O]    COG1138 Cytochrome c biogenesis factor
----------|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1    [C]    COG1140 Nitrate reductase beta subunit
|||||||||-|||---||||-|-----||-------------||||||-|--||||||||||||||  1    [C]    COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)
----------------|||||||||-||||||---|||----||||||||||||||||||||||--  1    [H    I]    COG1154 Deoxyxylulose-5-phosphate synthase
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1157 Flagellar biosynthesis/type III secretory pathway ATPase
----------------||--|||||||||||---||||----||||||||||||||||||||||||  1    [K]    COG1158 Transcription termination factor
----------------||||||--||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG1159 GTPase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [R]    COG1160 Predicted GTPases
--||-------------|--||||||-----|||||||||||------|-------||||||||--  1    [E]    COG1164 Oligoendopeptidase F
---|--------------||------||||-|--|||-----|||||-||||---------|----  1    [H    Q]    COG1169 Isochorismate synthase
---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--||||||||  1    [E]    COG1171 Threonine dehydratase
-------------||-||||||||||||||||||||||----||||||||||||||||||||||||  1    [J]    COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
----------------||||||||||||||||||||||-|--||||||||||||||||||||||||  1    [J]    COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases
-----------------|--|-----|---||||||||----|||||-||||-|||||||||||--  1    [J]    COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
--|-----|-------|||||----|||||||||-|||||----------------||||||||||  1    [J]    COG1189 Predicted rRNA methylase
|--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||--  1    [L]    COG1194 A/G-specific DNA glycosylase
----------|-------|||||-|-||||||||||||----|||||-|||||------|||||||  1    [L]    COG1195 Recombinational DNA repair ATPase (RecF pathway)
-||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||--  1    [D]    COG1196 Chromosome segregation ATPases
-----------------|||||||||||||||||||||----||||||||||||||||||||||||  1    [L    K]    COG1197 Transcription-repair coupling factor (superfamily II helicase)
----------------||||||--||||||||||||||----|||||-||||||||||||||||||  1    [L    K]    COG1200 RecG-like helicase
|||||||||||||------|------|||-------------|||----|-----|---|||||--  1    [R]    COG1201 Lhr-like helicases
----------------||||||---------|||||||---------------------|||||--  1    [J]    COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation
----------------||||||----||||||||||||----||||||||||||||||||||||||  1    [M]    COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
|||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||--  1    [M]    COG1210 UDP-glucose pyrophosphorylase
------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||--  1    [I]    COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [O]    COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone
------------------||||----||||||||||||----||||||||||||||||||||||||  1    [T]    COG1217 Predicted membrane GTPase involved in stress response
-------------||-|-||--||--||||------------|||||||||||-----||||||||  1    [P]    COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase
-------------|--||||||||||||||||||||||----||||||||||||||||||||||||  1    [O]    COG1219 ATP-dependent protease Clp, ATPase subunit
----------------||-------|--------||||----|||||||||||--|||||||||||  1    [O]    COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit
--||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-|  1    [O]    COG1225 Peroxiredoxin
|--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||--  1    [Q]    COG1228 Imidazolonepropionase and related amidohydrolases
--|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||--  1    [P]    COG1230 Co/Zn/Cd efflux system component
||||||||||----|-|-|||-||||----||||||||----||||---|-----|---|||||||  1    [R]    COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
-||------|------|-------------------------|||||-||||||||--||||||||  1    [S]    COG1238 Predicted membrane protein
---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||---  1    [C]    COG1252 NADH dehydrogenase, FAD-containing subunit
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1256 Flagellar hook-associated protein
----------------||------------------------||||||||-----|||||||||--  1    [N    O]    COG1261 Flagellar basal body P-ring biosynthesis protein
--|-----------|---||--||---||-------||----------||-|||||---|||||--  1    [S]    COG1262 Uncharacterized conserved protein
|||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||---  1    [H]    COG1270 Cobalamin biosynthesis protein CobD/CbiB
--||||--|-------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1    [C]    COG1271 Cytochrome bd-type quinol oxidase, subunit 1
-------------|||----||--|||||-||||||||----|||||-||--|||----|||||--  1    [R]    COG1272 Predicted membrane protein, hemolysin III homolog
--|||||||--||----|||-|--||----|---|||||||--------|-----|----||----  1    [R]    COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
--------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---|  1    [R]    COG1279 Lysine efflux permease
----------------||||||--------||||||||-|--|||||-||||||||---|||||--  1    [O]    COG1281 Disulfide bond chaperones of the HSP33 family
------------------||-------|||------------|||||-||||-|||---|||||||  1    [C]    COG1282 NAD/NADP transhydrogenase beta subunit
---------|-------|--|-||-|----||||||||||||------|----------|||----  1    [S]    COG1284 Uncharacterized conserved protein
----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||----  1    [S]    COG1285 Uncharacterized membrane protein
------------------------||-----|||||||----|||||-||||||||||||||||||  1    [R]    COG1286 Uncharacterized membrane protein, required for colicin V production
---|||----||||--|-||-|----||||------||----------||--||||||||||||||  1    [C]    COG1290 Cytochrome b subunit of the bc complex
----------------||------||----|----|||----|||||-||-----|||||||||--  1    [N]    COG1291 Flagellar motor component
--||------------|-||--||--|||--|--||||----|||||-||||---|--||||||||  1    [C]    COG1294 Cytochrome bd-type quinol oxidase, subunit 2
--|-------------|-||||||--||||||||||||-|--|||||-||||||||||||||||||  1    [S]    COG1295 Predicted membrane protein
--|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||---  1    [E]    COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
|||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----|||||||  1    [C]    COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
----||-----------|------------||----||----|||||---|--------||||---  1    [G]    COG1312 D-mannonate dehydratase
----------------|-|||||||||||||||||||||-|-||||||||||||||||||||||||  1    [U]    COG1314 Preprotein translocase subunit SecG
||||--||---------|---|----|-------||||----------||---------|||--||  1    [P]    COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit
----------------------||-------|||-----|--|||||-||||||||---|||||||  1    [S]    COG1322 Uncharacterized protein conserved in bacteria
-----------------||-||||--||||||||||||----|||||-||||||||---|||||--  1    [K]    COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains
---------------------|--||||||------||---------------------|||||||  1    [K]    COG1329 Transcriptional regulators, similar to M. xanthus CarD
--|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||--  1    [Q]    COG1335 Amidases related to nicotinamidase
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1338 Flagellar biosynthesis pathway, component FliP
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1    [M]    COG1346 Putative effector of murein hydrolase
-||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||--  1    [S]    COG1354 Uncharacterized conserved protein
|||-----||---||-||||-|----||||||--||||-----------|---|||---|||||--  1    [E]    COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase)
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1377 Flagellar biosynthesis pathway, component FlhB
--|---||------------||--------||--|-||----|||||-||||-|||-----|----  1    [R]    COG1380 Putative effector of murein hydrolase LrgA
------------------|||||||-||||||||||||||--|||||-||||||||---|||||||  1    [L]    COG1381 Recombinational DNA repair protein (RecF pathway)
||||||||||--|-----------||-----------------------------------|||||  1    [J]    COG1384 Lysyl-tRNA synthetase (class I)
----------------||||||--||||||||||||||||--||||||||||||||||||||||||  1    [S]    COG1385 Uncharacterized protein conserved in bacteria
--|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||--  1    [K]    COG1386 Predicted transcriptional regulator containing the HTH domain
----------------|---------||||------------|||||-||||-|||---|||||--  1    [O    T]    COG1391 Glutamine synthetase adenylyltransferase
||-|-----||||----|||-------||------|-|---------------------|||||--  1    [R]    COG1402 Uncharacterized protein, putative amidase
---|--------------||-|-----||||||-|||-----|||---|---|--|---|||||--  1    [V]    COG1403 Restriction endonuclease
|||||||||||||----------------------------------------------|||||--  1    [R]    COG1407 Predicted ICC-like phosphoesterases
-----------------|||-|----|||||------|----|||||-|||-|--|---|||||--  1    [E]    COG1410 Methionine synthase I, cobalamin-binding domain
-----------------||||-||--||||||||||||||||----------|--|||||||||--  1    [K]    COG1420 Transcriptional regulator of heat shock gene
||||-----|--------||-------||--------------------|-----|---||||---  1    [H]    COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases
||-|--||-||------|||----||--------------------------|--|---|||||--  1    [S]    COG1430 Uncharacterized conserved protein
||||--||||------|-||-|--|-|---------------------||----|-||||||||--  1    [S]    COG1432 Uncharacterized conserved protein
----------------|-------||----------------|||||-||||||||||||||||||  1    [M]    COG1452 Organic solvent tolerance protein OstA
|-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||---  1    [C]    COG1454 Alcohol dehydrogenase, class IV
----------------|-||-------|||------------|||||-||||||||||||||||||  1    [Q]    COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
----------------||||-|||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG1466 DNA polymerase III, delta subunit
-----------|--|--|||-|---|||||||---|||----|||||-||||||||---|||||||  1    [G]    COG1472 Beta-glucosidase-related glycosidases
-------------||------|-----||-------------|||||-||--||||---|||||||  1    [R]    COG1485 Predicted ATPase
--|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||---  1    [H]    COG1488 Nicotinic acid phosphoribosyltransferase
|---||--|-|||---||||----------|------|----|||||-||||-------|||-|--  1    [R]    COG1489 DNA-binding protein, stimulates sugar fermentation
||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||--  1    [H]    COG1492 Cobyric acid synthase
---------|----------|---|-----||||||||||||----------||||---|||||--  1    [T]    COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism
--|---------------||||----|||||-----||----|||-|-|-||---------|||--  1    [G]    COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins
----------------|-||||||-||||||---|-||----|||||-||||||||--||||||||  1    [S]    COG1496 Uncharacterized conserved protein
----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-|||||||  1    [I]    COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes
----------------|-----||||----|----|||----|||||-||--||||||||||||--  1    [K]    COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
-|----||--------------------------|-|------------------|---|-|----  1    [K]    COG1510 Predicted transcriptional regulators
-----------------|||----|------|----||----|||----|-|---|-----|||--  1    [R]    COG1512 Beta-propeller domains of methanol dehydrogenase type
|||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||--  1    [J]    COG1514 2'-5' RNA ligase
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1519 3-deoxy-D-manno-octulosonic-acid transferase
|||-||--|-||--------------|||-----||||----|||||-||||---|--||||||--  1    [C]    COG1526 Uncharacterized protein required for formate dehydrogenase activity
---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---|||||||  1    [J]    COG1530 Ribonucleases G and E
-||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-|  1    [L]    COG1533 DNA repair photolyase
-----------------|------------------|-----|||-|-||-----------|----  1    [Q]    COG1535 Isochorismate hydrolase
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N]    COG1536 Flagellar motor switch protein
----------------|-|||---------------------|||||-||||||||||||||||||  1    [M    U]    COG1538 Outer membrane protein
-------------||---||||||--||||||||||||----|||||-||||||||||||||||--  1    [H]    COG1539 Dihydroneopterin aldolase
----------------||||||-|-|||||||||||||----|||||-|||||--|---|||||||  1    [J]    COG1544 Ribosome-associated protein Y (PSrp-1)
---|------------||||||----|||||-||-||||||||||||-||--||||||||||||--  1    [R]    COG1546 Uncharacterized protein (competence- and mitomycin-induced)
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1558 Flagellar basal body rod protein
----------------|---||--||||||||||-|||----|||||-||||||||||||||||||  1    [R]    COG1559 Predicted periplasmic solute-binding protein
--------------------|-||--||||------------|||||-||||||||||||||||||  1    [M]    COG1560 Lauroyl/myristoyl acyltransferase
----------------||--|----|----|----|||----|||||-||||||||---|||||--  1    [S]    COG1561 Uncharacterized stress-induced protein
|--|-------|-||---||-|----|||-----|-|---------------||||---|||||--  1    [I]    COG1562 Phytoene/squalene synthetase
-------------||--|--||--|-----|||||||-------------------||-||||---  1    [H]    COG1564 Thiamine pyrophosphokinase
----------------|-||--------------------------------||||||||||||||  1    [S]    COG1565 Uncharacterized conserved protein
-----------------|-|||||--||||||||||||----|||||-||||||||||||||||||  1    [L]    COG1570 Exonuclease VII, large subunit
-----------------|--||--------||||||||||--|||||-||||||||||||||||--  1    [S]    COG1576 Uncharacterized conserved protein
||-|--||-||||----|||||----|||||-----------|||||-||-||------|||||--  1    [O    U]    COG1585 Membrane protein implicated in regulation of membrane protease activity
||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||---  1    [H]    COG1587 Uroporphyrinogen-III synthase
------------------||-|--||||||||||||||----|||||-||||||||---|||||||  1    [M]    COG1589 Cell division septal protein
|-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||--  1    [C]    COG1600 Uncharacterized Fe-S protein
||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||--  1    [E]    COG1605 Chorismate mutase
---|||----|||--------|||--|-------||||----||||||||||-|||||||||||--  1    [I]    COG1607 Acyl-CoA hydrolase
-------------|---|--------|||-|----|||----------||--||||--|||||---  1    [S]    COG1610 Uncharacterized conserved protein
---|--------|||-|-||-|----||||----||||-----------|--|--|---|||||||  1    [O]    COG1612 Uncharacterized protein required for cytochrome oxidase assembly
------------------||-------|||-------|----|||||--|--||||---|||||--  1    [P]    COG1613 ABC-type sulfate transport system, periplasmic component
|-|---||---|----||------------|-----||---------------------||||---  1    [S]    COG1633 Uncharacterized conserved protein
||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||--  1    [H]    COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
------------------||-|--------------|-----||||---------|-----|----  1    [S]    COG1649 Uncharacterized protein conserved in bacteria
-------------------|-|--||---------||-----|||-|-||-|||||---|||||--  1    [S]    COG1652 Uncharacterized protein containing LysM domain
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG1663 Tetraacyldisaccharide-1-P 4'-kinase
------------------------||----|---||||----|||||-||---------|||||--  1    [S]    COG1671 Uncharacterized protein conserved in bacteria
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1677 Flagellar hook-basal body protein
---------------------|||--||||------------|||||-||||||||---|||||||  1    [K]    COG1678 Putative transcriptional regulator
--|-----|-------|-||------|||||||-||||--------|-||-||||---|-||||||  1    [G    M]    COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1684 Flagellar biosynthesis pathway, component FliR
----------------|---||---|--------||||||||-----------------|||||--  1    [S]    COG1692 Uncharacterized protein conserved in bacteria
--|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-|  1    [R]    COG1694 Predicted pyrophosphatase
---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||--  1    [T]    COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase
-||--------------|--|---|-------||-|--||---|||---|-|---|---|||||--  1    [S]    COG1704 Uncharacterized conserved protein
-----------------|-------------||-|||-----|||||-||-----|-----|----  1    [N    U]    COG1705 Muramidase (flagellum-specific)
----------------||-------|----------------||||||||-----|||||||||--  1    [N]    COG1706 Flagellar basal-body P-ring protein
|--------|--------||-------||||----|||----------|||--|||||||||||||  1    [S]    COG1714 Predicted membrane protein/domain
--|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||--  1    [R]    COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
-----------------|-|||----||||||||||||----|||||-||||||||||||||||||  1    [L]    COG1722 Exonuclease VII small subunit
----------------|-------------------------|||||-||--||||---|||||||  1    [S]    COG1729 Uncharacterized protein conserved in bacteria
---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||---  1    [M]    COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
----------------|-----||||----|-----||----||||||||||||||--||||||||  1    [T]    COG1734 DnaK suppressor protein
--||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||---  1    [S]    COG1738 Uncharacterized conserved protein
--||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||----  1    [S]    COG1739 Uncharacterized conserved protein
--|-||----|-------||------|||-|-----------|||||-||-|---|---|||||--  1    [R]    COG1741 Pirin-related protein
----|||-|-|-|||---||-|-----------|---|----------|--|----|||||||---  1    [E]    COG1748 Saccharopine dehydrogenase and related proteins
----------------|-------||----|----|------||||||||-----|||||||||--  1    [N]    COG1749 Flagellar hook protein FlgE
------------------||-|---|||||----------------------|------|||||||  1    [R]    COG1754 Uncharacterized C-terminal domain of topoisomerase IA
||||||||||||||||||||-|--||||||||||||||----|||||-||||||||||||||||||  1    [K]    COG1758 DNA-directed RNA polymerase, subunit K/omega
--------------------||----||||||||||||----|||||-||||-|||||||||||--  1    [E]    COG1760 L-serine deaminase
--------------------|-|||||---||||||||-||||||||-||||-|||---|||||--  1    [G    T]    COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
|||||-|||||||---|-----------------||||----|||||-|-||---|--|||||---  1    [H]    COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein
----||---------------|----|----|--|||---|||||-|-||--|--|---|||||--  1    [O]    COG1764 Predicted redox protein, regulator of disulfide bond formation
-------------------|------||||---|--------|||||-||--|------|||||||  1    [E]    COG1770 Protease II
---------------------|----||||-||||-|--||||||||------------|-|----  1    [F]    COG1780 Protein involved in ribonucleotide reduction
--||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|----  1    [P]    COG1785 Alkaline phosphatase
||||||--||||------||||-----||-|----|-|--------|--|-----|---||||---  1    [H]    COG1797 Cobyrinic acid a,c-diamide synthase
-----------------||------|----|----|||----|||||-|-||---|---|||----  1    [G]    COG1803 Methylglyoxal synthase
---------------------|------------||||----|||||-||--||||---|||||||  1    [S]    COG1806 Uncharacterized protein conserved in bacteria
------|||-------|-|||---------|-----|-----|||||--|--||||---|||||--  1    [M]    COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1815 Flagellar basal body protein
-----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||--  1    [G]    COG1820 N-acetylglucosamine-6-phosphate deacetylase
----------------||||-|||||||||----||||----||||||||||||||||||||||||  1    [J]    COG1825 Ribosomal protein L25 (general stress protein Ctc)
--||||--|||||---|-||-|----||||----||||----|||||-||||||||||||||||||  1    [U]    COG1826 Sec-independent protein secretion pathway components
||||||||||||----||||-|----||||-|--||||--------------------|-||||--  1    [F]    COG1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component
--|----------------|||----||||-||||||------||-|--||-||||---|||||-|  1    [I]    COG1835 Predicted acyltransferases
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1    [C]    COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
||||||||||||||||||--||--||||||||||||||----||||||||||||||----||||||  1    [J]    COG1841 Ribosomal protein L30/L7E
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N]    COG1843 Flagellar hook capping protein
----------------||--|-||-|||||||||||||----||||||||||||||||||||||||  1    [U]    COG1862 Preprotein translocase subunit YajC
||||--||---------|---|----|-------||||----------||---------|||--||  1    [P]    COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit
------------||------||------------|-||----|||||-||||------|||||---  1    [C]    COG1866 Phosphoenolpyruvate carboxykinase (ATP)
----------------||------||----|----|||----||||||||-----||||||||---  1    [N]    COG1868 Flagellar motor switch protein
---||||||--||--------|----||||-------|----|||----------|---|||||--  1    [I]    COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit
----------------||----||||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1886 Flagellar motor switch/type III secretory pathway protein
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1    [C]    COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit
---|--|||||||||------|------------||------|||||-||-|----||||||||--  1    [R]    COG1896 Predicted hydrolases of HD superfamily
-----------------|------------||-|--||----|||||-|---------||||----  1    [E]    COG1897 Homoserine trans-succinylase
|-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||--  1    [M]    COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes
|||-||--||||------|||---------|----|----------|--|-----|---|-|----  1    [H]    COG1903 Cobalamin biosynthesis protein CbiD
|-------------|-||||-|-----||-------------||||||-|--||||---|||||||  1    [C]    COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit
----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||---  1    [P]    COG1914 Mn2+ and Fe2+ transporters of the NRAMP family
||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||---  1    [S]    COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain
-----------------|||-|--|-----|---|||-----|||||-|---|------|-|||--  1    [M]    COG1922 Teichoic acid biosynthesis proteins
-|--------------||------------|---||||----|||||-||||||||----||||--  1    [R]    COG1923 Uncharacterized host factor I protein
--------------------|||||||---||||||||||||||||||||||||||---|||||--  1    [G]    COG1925 Phosphotransferase system, HPr-related proteins
--|----------||----|------||||-|---|||----||||||||||||||--||||||--  1    [H    E]    COG1932 Phosphoserine aminotransferase
----------------|-||----------------------|||||-||||||||||||||||--  1    [S]    COG1934 Uncharacterized protein conserved in bacteria
-------------|-|----------||||------------|||||-|||||------|||||--  1    [I]    COG1946 Acyl-CoA thioesterase
----------------|||||||-|-|||||---|||||---||||||||||||||||||||||--  1    [I]    COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase
|||---|||||-----||------------|------|----|||||-||--||||-----||---  1    [C]    COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
-|----------------------------------------||||||||||||||---|||||||  1    [U]    COG1952 Preprotein translocase subunit SecB
-----------||||---------------------|-----|||||--|-----|----||||--  1    [F    H]    COG1953 Cytosine/uracil/thiamine/allantoin permeases
-----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||--  1    [F]    COG1957 Inosine-uridine nucleoside N-ribohydrolase
|--------|||----||||||---||||||||||-||----||||||||--||||--||||||--  1    [V]    COG1968 Uncharacterized bacitracin resistance protein
--|---------------|-||----||||-||||||-----|||||-|||||--|---|||||--  1    [M]    COG1970 Large-conductance mechanosensitive channel
-----------------|||-|----||||||--||||----|||||-|||||--|---|||||--  1    [K    T]    COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases)
----------|||--------|-----||-------||----|||----|-----|---|||||--  1    [O]    COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family
--||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||--  1    [H]    COG1977 Molybdopterin converting factor, small subunit
------------------||-----------------------------|--||||||||||||||  1    [S]    COG1981 Predicted membrane protein
||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||--  1    [H]    COG1985 Pyrimidine reductase, riboflavin biosynthesis
----------------||------||----|----|||----||||||||-----|||||||||--  1    [N    U]    COG1987 Flagellar biosynthesis pathway, component FliQ
-||---||-|------||---------||--------------------------------|-|--  1    [S]    COG1993 Uncharacterized conserved protein
----------------|-|||----------------|----|||||-||-|||||||||||||--  1    [H]    COG1995 Pyridoxal phosphate biosynthesis protein
---|------|-|||-|----|--------------||----------||--||||--||||||||  1    [R]    COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems
--|-------------|||||---------||||||||----|||||-||||||||---||||--|  1    [L]    COG2003 DNA repair proteins
---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||--  1    [E]    COG2008 Threonine aldolase
---|||--|-|-|||------|||---|||----|-||----|||||-||--||||||||||||||  1    [C]    COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit
--------------------||-||-|---||||||||----|||||-||||||||||||||||--  1    [P]    COG2011 ABC-type metal ion transport system, permease component
----||-----|-||--|||||--------||-|||||----|||-|-|-||-|||---|||||--  1    [G]    COG2017 Galactose mutarotase and related enzymes
||--||||-||||------------------------------------------------|----  1    [F]    COG2019 Archaeal adenylate kinase
----------------|-||||----|||||-----||----|||||-||--||||--||||||--  1    [H]    COG2022 Uncharacterized enzyme of thiazole biosynthesis
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  1    [C]    COG2025 Electron transfer flavoprotein, alpha subunit
--|----------||-|----|-----||||-----|-----|||||-|--|-|||----||-|--  1    [P]    COG2032 Cu/Zn superoxide dismutase
|||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||--  1    [H]    COG2038 NaMN:DMB phosphoribosyltransferase
||----||-|----------------|---|-----|-----|||-|--|||-------||||---  1    [C]    COG2055 Malate/L-lactate dehydrogenases
-----------|--------||----|||-|-|---||----|------||----|||-|||||-|  1    [I]    COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
--------|-|||---|-||------||||------------|||||-|||||--|--||||||--  1    [T]    COG2062 Phosphohistidine phosphatase SixA
----------------||------------------------||||||||-----|||||||||--  1    [N]    COG2063 Flagellar basal body L-ring protein
----------------|---|---------------------|||||-|||||||-||-|||||--  1    [I]    COG2067 Long-chain fatty acid transport protein
--------|----|--||-|||----|||-||||||||-----------|--||||||||||-|--  1    [R]    COG2070 Dioxygenases related to 2-nitropropane dioxygenase
--------------|-----|------|||||||-|------|||----|--------||||||||  1    [R]    COG2071 Predicted glutamine amidotransferases
--||---------------|-|-----|||||---|||----|||||-||---||---||||||--  1    [P]    COG2076 Membrane transporters of cations and cationic drugs
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2082 Precorrin isomerase
---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||--  1    [C]    COG2086 Electron transfer flavoprotein, beta subunit
------------------||||----|||-|----|-|----|||-|-||-----|---||||---  1    [H]    COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase
---||||||-|||-------||----||||-----|||--------|--|-----|---|||||--  1    [S]    COG2096 Uncharacterized conserved protein
||----------------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2099 Precorrin-6x reductase
|-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||--  1    [H]    COG2104 Sulfur transfer protein involved in thiamine biosynthesis
--||||||--|------|||||-----||-------------|||||-||-----|---||||---  1    [H]    COG2109 ATP:corrinoid adenosyltransferase
||||--||---------|||-|----|-------||||----------||---------|||--||  1    [P]    COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit
-----------------|-------------|----||----|||||---|--------||||---  1    [G]    COG2115 Xylose isomerase
--|---||-|-|-|||-----|----||||----|-||----|--|-------------||||---  1    [S]    COG2120 Uncharacterized proteins, LmbE homologs
---|---------||---||-|----|||||-----||-----------|--|--|--||||||--  1    [Q]    COG2124 Cytochrome P450
------------------||-|----|||||-----------|||||-||--||||||||||||--  1    [S]    COG2127 Uncharacterized conserved protein
--|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||--  1    [S]    COG2128 Uncharacterized conserved protein
---|---------|-----|------||||------|-----|||-|--|---------||||---  1    [S]    COG2135 Uncharacterized conserved protein
----||--|---|--------|-----|||------------|||||-||--||||---|||||||  1    [C]    COG2142 Succinate dehydrogenase, hydrophobic anchor subunit
---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||--  1    [M]    COG2148 Sugar transferases involved in lipopolysaccharide synthesis
--------------|---|-------|||--|-----|----|||-|-||-----------|----  1    [R]    COG2153 Predicted acyltransferase
---|------||-||-|-||------||||------------------||--|--|----||||--  1    [H]    COG2154 Pterin-4a-carbinolamine dehydratase
------------------||-|||---||-------------|||||-|||||------|||||--  1    [R]    COG2166 SufE protein probably involved in Fe-S center assembly
---------|-------|--------||||||-|||||----||||||||||||||||||||||||  1    [E]    COG2171 Tetrahydrodipicolinate N-succinyltransferase
-------------------|||----||||||||-|||----|||||-|||||||----|||||--  1    [D]    COG2177 Cell division protein
--------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|----  1    [C]    COG2180 Nitrate reductase delta subunit
--------|-|---------------|||-----|-|-----|||-|--|-----|-----|----  1    [C]    COG2181 Nitrate reductase gamma subunit
-------------|||---||---|-|---|||||||||---|||||-||||||||---||||---  1    [K]    COG2183 Transcriptional accessory protein
---||||||--||-------||----||||-------|----|||----------|---|||||--  1    [I]    COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)
------------------||-------|||------------|||||-||--||||---|||||--  1    [P]    COG2193 Bacterioferritin (cytochrome b1)
------------------------------------------|||||-|||||||-||||||--||  1    [R]    COG2194 Predicted membrane-associated, metal-dependent hydrolase
|-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||--  1    [T]    COG2203 FOG: GAF domain
|-||--||---------|---|----|-------||||----------||---------|||--|-  1    [P]    COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit
-|------------------|---|-----------------|||||---||---|---||||---  1    [R]    COG2215 ABC-type uncharacterized transport system, permease component
||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--|  1    [R]    COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold
|-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||--  1    [M]    COG2222 Predicted phosphosugar isomerases
----------------|---------||||----|-||----|||-|--|-----|----||-|--  1    [P]    COG2223 Nitrate/nitrite transporter
-----------|-||------|----||||-------|----|||||-||-----|---|||||--  1    [C]    COG2224 Isocitrate lyase
----------||-|-------|----||||-------|----|||||-||-----|---|||||--  1    [C]    COG2225 Malate synthase
--|-||----||-||-||||||||--||||----||||----|||||-||-|||||||||||||||  1    [H]    COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis
-------------||---||-|--------------------|||||-||-|||||---|||||||  1    [H]    COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase
--|-------------|----|----|||||-----------|||||-||-----|||||||||--  1    [M]    COG2230 Cyclopropane fatty acid synthase and related methyltransferases
-------|------|--|--||----|---||||||||----|||||-||||-|||---|||----  1    [F]    COG2233 Xanthine/uracil permeases
|----------------||||-|||||||-|---|-||||-----|--||--|||----|||||||  1    [P]    COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain)
-------------||------|---||---|-|---------|||||--|||-------|||||--  1    [H]    COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase
||||||--||||------|||-----|||-|----|----------|--|-----|---||||---  1    [H]    COG2241 Precorrin-6B methylase 1
||||||--||||------|||-----|||-|----|----------|--|---------||||---  1    [H]    COG2242 Precorrin-6B methylase 2
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2243 Precorrin-2 methylase
-----------------||||||||||||||||||||||||||||||-||||||||||||||||||  1    [L]    COG2255 Holliday junction resolvasome, helicase subunit
-------------||--|--||----|||||||||||||---|||||-||||||||||||||||--  1    [L]    COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
---------------------|----|||-|---||||----|||-|--||----|--||-|----  1    [S]    COG2258 Uncharacterized protein conserved in bacteria
---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||--  1    [S]    COG2259 Predicted membrane protein
-|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||--  1    [R]    COG2262 GTPases
----------------||||||--------||||||||----|||||-||||||||||||||||--  1    [J]    COG2264 Ribosomal protein L11 methylase
------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||--  1    [J]    COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase
-------------||-|---------|||||----|||---------------------|||||--  1    [R]    COG2270 Permeases of the major facilitator superfamily
---|--|--|--|---|----|---|-------|||||---------------------||||---  1    [E]    COG2309 Leucyl aminopeptidase (aminopeptidase T)
------------------|--|--------------||-----------|---------||||---  1    [S]    COG2318 Uncharacterized protein conserved in bacteria
--|----------|||-|||||--------------------------|----------|||||--  1    [R]    COG2319 FOG: WD40 repeat
---------------------|----|||---|---------|||||--|-|---|---||||---  1    [R]    COG2321 Predicted metalloprotease
--|---------------||-|----|||-------------------||-----|--||||||--  1    [S]    COG2326 Uncharacterized conserved protein
|----------------|||-|--------|-----------|||-|------------|-|----  1    [S]    COG2327 Uncharacterized conserved protein
--|------------------|--------------------|||||-|||||------|||||||  1    [O]    COG2332 Cytochrome c-type biogenesis protein CcmE
-------------------|-|-----||-|---||||----|||-------|||----|||---|  1    [T]    COG2337 Growth inhibitor
--------|----|-|---|||---||---|---||||-----------|---------|||||--  1    [S]    COG2340 Uncharacterized protein with SCP/PR1 domains
------------------|--|----||||----|-||-----------------|--||||||--  1    [R]    COG2346 Truncated hemoglobins
------------------||||----|---|-----|-----|||||-||||-|||---|||||--  1    [S]    COG2350 Uncharacterized protein conserved in bacteria
--------------|------|--------------||----|||-|--|-----|--||||||--  1    [R]    COG2351 Transthyretin-like protein
---------------------|----|||-------------|||-|-||---|-------|-|--  1    [S]    COG2354 Uncharacterized protein conserved in bacteria
------||--|||-|------|||-----------|-|-----------|-----|---|||||--  1    [E]    COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
---|----|---|-----|--|---------------|----------||-|--------||--||  1    [R]    COG2358 TRAP-type uncharacterized transport system, periplasmic component
------------------||-|--------------------|||||-||--||||--||||||--  1    [O]    COG2360 Leu/Phe-tRNA-protein transferase
--------------|----|-|------------||||----|||||-||||-------|||||--  1    [S]    COG2363 Uncharacterized small membrane protein
---------|--------||-|--------------------|||||-||||||||---|||||--  1    [O]    COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases
--------------------||----|||||---||||----|---|-||--|-||--||||||--  1    [K]    COG2378 Predicted transcriptional regulator
----||||--|||----|---|---------------------------|-----|---||||---  1    [G]    COG2379 Putative glycerate kinase
--|-----|------------|--------------------|||||-|||||------|||||--  1    [O]    COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component
--------|---|-------||----|----|--||------|||---||-|-------|||||--  1    [R]    COG2388 Predicted acetyltransferase
|-||||--|||||||-----------|-------|----------|---|-----|---||||---  1    [E]    COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog
||----||-|---------|-------------------------|---|---||----|-|----  1    [S]    COG2510 Predicted membrane protein
----------|-|--------|----|-----||||||---------------------||||---  1    [R]    COG2514 Predicted ring-cleavage extradiol dioxygenase
----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||--  1    [S]    COG2606 Uncharacterized conserved protein
----------------|-||----------|------------------|---|||--||||||--  1    [R]    COG2607 Predicted ATPase (AAA+ superfamily)
--||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||----  1    [P]    COG2608 Copper chaperone
-------------------|-|--|-----|-----------|||||--|-|---|--||||-|--  1    [S]    COG2717 Predicted membrane protein
----|------|------------------|-----||----|||||--------|--||||||--  1    [G]    COG2721 Altronate dehydratase
-------------------|||----||||||||||||||----------------||||||||--  1    [K]    COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination
-----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||--  1    [E]    COG2755 Lysophospholipase L1 and related esterases
---|-------|---------|----|---|---||||----------|---|--|---|||||--  1    [Q]    COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis
--------------|---||-|-----||-------------------||-----|---|||||--  1    [R]    COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease
---------------------|----|---|--|-||-----|||-|--|-----|--|--|----  1    [P]    COG2807 Cyanate permease
----------------||||||||||||||||||||||||||||||||||||||||||||||||||  1    [L]    COG2812 DNA polymerase III, gamma/tau subunits
--|----------||------|----|||-|-----------|||||-||||-------|||||--  1    [L]    COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
--------------------------||||-|||||-|----|||||-||||-|||---|||||--  1    [L]    COG2818 3-methyladenine DNA glycosylase
------------------||----------------------||||||||||-|||---|||||--  1    [M]    COG2821 Membrane-bound lytic murein transglycosylase
--------------------------|----|||-|------|||||-||||-|||||||||||--  1    [P]    COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism
---|----------------|----------|||||||----|||||-||---||-----||||--  1    [L]    COG2827 Predicted endonuclease containing a URI domain
--------------------||-----------||-------|||-|-||||-||----|||----  1    [S]    COG2832 Uncharacterized protein conserved in bacteria
--------------------------------------------------||-|||--||||----  1    [S]    COG2833 Uncharacterized protein conserved in bacteria
-|||----|-------|----|--||----|-----||----|||||-||||||||||||||||||  1    [M]    COG2834 Outer membrane lipoprotein-sorting protein
--||------|||-------------||||------------|||||-||-|||||----||||--  1    [S]    COG2835 Uncharacterized conserved protein
------------------------|-----------------||||||||||||||---|||||--  1    [S]    COG2840 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-|-||-|||--|----  1    [S]    COG2841 Uncharacterized protein conserved in bacteria
--------------------------|||-------------|||||-||||-|||---|||||--  1    [O]    COG2844 UTP:GlnB (protein PII) uridylyltransferase
------------------------|----------------------------||---|||||---  1    [S]    COG2845 Uncharacterized protein conserved in bacteria
----------|-----|----|----|---------------------||-|-|||--||||||||  1    [S]    COG2847 Uncharacterized protein conserved in bacteria
--------|-----------|-----|----|||||------|||||--|||-|||--||||||--  1    [S]    COG2855 Predicted membrane protein
-------------------|||---|-||-|--|||||--------------||-|-----|----  1    [E]    COG2856 Predicted Zn peptidase
-------------||-|-------------------||----------||--||||||||||||||  1    [C]    COG2857 Cytochrome c1
---|------||---------|----|----||---||----|||||-||||---|--||||||--  1    [S]    COG2860 Predicted membrane protein
-------------||---------------------------|||||-||-|||||---|||||||  1    [I]    COG2867 Oligoketide cyclase/lipid transport protein
--|-||||--||||---|--||--------|------|----------||-----|---||||---  1    [R]    COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain
--||---------||--|---|----|||-||---|-|-----------|-|---|--|||||---  1    [E]    COG2873 O-acetylhomoserine sulfhydrylase
||||||--||||------|||------||-|----|----------|--|-----|---||||---  1    [H]    COG2875 Precorrin-4 methylase
----------------|---|-||------------------|||||-||||||||||||||||||  1    [M]    COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
-------------------|-|----||||||||-|||----|||||-|||||||----|||||--  1    [D]    COG2884 Predicted ATPase involved in cell division
--|---------|-----------|-||||-------------------------|||||||||||  1    [L]    COG2887 RecB family exonuclease
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||  1    [J]    COG2890 Methylase of polypeptide chain release factors
--------------------|---------||||-||-----|||||----|||||---|||||--  1    [G]    COG2893 Phosphotransferase system, mannose/fructose-specific component IIA
----------------||||||--------|----|||----||||||||--||||||-||||---  1    [D]    COG2894 Septum formation inhibitor-activating ATPase
--------------------------|||-|-----------||||||||--||||---|||||--  1    [P]    COG2895 GTPases - Sulfate adenylate transferase subunit 1
|||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||--  1    [H]    COG2896 Molybdenum cofactor biosynthesis enzyme
|--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||--  1    [P]    COG2897 Rhodanese-related sulfurtransferase
--|-----------------------||||-|--|||------------|--|--|---|||||--  1    [S]    COG2898 Uncharacterized conserved protein
---------------------|-----|||-|--------------------|------|||----  1    [S]    COG2899 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|||||||----||||---  1    [S]    COG2900 Uncharacterized protein conserved in bacteria
-------------||------------|||------------------||--|------|||||||  1    [E]    COG2902 NAD-specific glutamate dehydrogenase
------------------------------------------||||||||||||||---|||||--  1    [S]    COG2911 Uncharacterized protein conserved in bacteria
------------------------------------------||||||||||||||---|||||||  1    [J]    COG2913 Small protein A (tmRNA-binding)
------------------------------------------||||||||||-|||----||||||  1    [D]    COG2917 Intracellular septation protein A
------------------------||||||-|||||||----||||||||||||||---|||||||  1    [D]    COG2919 Septum formation initiator
------------------------------------------|||||-||||||||---|||||||  1    [L]    COG2927 DNA polymerase III, chi subunit
------------------||--------------------------|-|---|||-----||-|--  1    [S]    COG2929 Uncharacterized protein conserved in bacteria
--------------------|----------||-|--------|--|--||||||----|||||--  1    [K]    COG2932 Predicted transcriptional regulator
-------------||---------------------------------||--|--|--||||||--  1    [O]    COG2935 Putative arginyl-tRNA:protein arginylyltransferase
-------------||---------------------------|||||-||||||||---|||||||  1    [S]    COG2938 Uncharacterized conserved protein
------------------||----------------------|||-|-----|--|---|||||--  1    [G]    COG2942 N-acyl-D-glucosamine 2-epimerase
---|----|----------------------------------------|--||||---|||||||  1    [R]    COG2945 Predicted hydrolase of the alpha/beta superfamily
--------------|---||-|---------------------------|--|--|---||||---  1    [S]    COG2947 Uncharacterized conserved protein
----------------------------------------------------|--|||-|||||||  1    [U]    COG2948 Type IV secretory pathway, VirB10 components
------------------------------------------|||||-||--||||---||||---  1    [S]    COG2960 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||||||---|||||-|  1    [R]    COG2961 Protein involved in catabolism of external DNA
--------------------------|-------||||----|||||-||||---|---|||||--  1    [R]    COG2962 Predicted permeases
---------------------|--------------------|||||-||--|--|---|||||--  1    [P]    COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport
--||--------------||-------||--------|----|||||-|---|------|||||--  1    [S]    COG2968 Uncharacterized conserved protein
--------------------------||||------------|||||-||---------|-||---  1    [Q]    COG2977 Phosphopantetheinyl transferase component of siderophore synthetase
------------------------------------------|||-|-||-|-||----||||---  1    [S]    COG2979 Uncharacterized protein conserved in bacteria
------------------|-----------------------|||||-||||-------||||---  1    [E]    COG2981 Uncharacterized protein involved in cysteine biosynthesis
------------------------------------------|||||-||---|||----|||-||  1    [M]    COG2982 Uncharacterized protein involved in outer membrane biogenesis
-|----------------------------------------|||||-||||-------|||||--  1    [S]    COG2983 Uncharacterized conserved protein
----------------|---|-||--|-----||--------------||-----|---||||-||  1    [R]    COG2984 ABC-type uncharacterized transport system, periplasmic component
---|||--------------||----------|-|-||-------|--||-----|---|||||--  1    [E]    COG2987 Urocanate hydratase
------------------------------------------------||---|||||||||||--  1    [C]    COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit
------------------------------------------|||||-|-||----|||-||||-|  1    [P]    COG3004 Na+/H+ antiporter
--------------------|----||----|||||---|--|||||-|-||---------|----  1    [G]    COG3010 Putative N-acetylmannosamine-6-phosphate epimerase
-------------------|-|--------------------|||||-|--|-------|-|||--  1    [S]    COG3021 Uncharacterized protein conserved in bacteria
--------------------|---------------------|||||-||||||||---|||||-|  1    [V]    COG3023 Negative regulator of beta-lactamase expression
------------------------------------------|||||-||||-|||----||||--  1    [S]    COG3024 Uncharacterized protein conserved in bacteria
-----------------------|------|---||||----|||||-|||||||----|||||||  1    [S]    COG3027 Uncharacterized protein conserved in bacteria
--||----------------------||-------|||----|||||-||-|-||----||||---  1    [R]    COG3030 Protein affecting phage T7 exclusion by the F plasmid
----------------|-------------------------|||||-||------|||||||---  1    [S]    COG3034 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||---|||---||||---  1    [S]    COG3045 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-||--|---|-|||||  1    [M]    COG3047 Outer membrane protein W
--|---------------|------------|--|-|---------|-|----------|-||---  1    [M]    COG3049 Penicillin V acylase and related amidases
--------------------|---------------------|||||-|-||---------|----  1    [S]    COG3055 Uncharacterized protein conserved in bacteria
---------------------|--------------------|||||--||||------|||||--  1    [O]    COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes
------------------------------------------|||||-|-||-------||||---  1    [R]    COG3106 Predicted ATPase
--------------------------||||------------|||||-|||||--|---|||||--  1    [O]    COG3118 Thioredoxin domain-containing protein
--||---|------|------------||-------------|||||--|||-------|||||--  1    [P]    COG3119 Arylsulfatase A and related enzymes
----------------------------------||||----||||||-|--|--|---|-|||--  1    [C]    COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4
------------------------------------------|||||-||---------|-||---  1    [S]    COG3126 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||||--  1    [Q]    COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component
---------------------|----|---------------|||-|-||----------|||---  1    [Q]    COG3135 Uncharacterized protein involved in benzoate metabolism
--------------|----|------||||------------|||-|-||--|--|---|||||--  1    [L]    COG3145 Alkylated DNA repair protein
------------------||-----------------------------|--|--|---|||||--  1    [S]    COG3146 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||-----|---|||----  1    [I]    COG3154 Putative lipid carrier protein
--|-----------------------|----||---------|||||-||--|--|---|||||--  1    [P]    COG3158 K+ transporter
---------------------|--------------------------||--|-------||----  1    [S]    COG3169 Uncharacterized protein conserved in bacteria
-------------||----------------------------------|-----|---|||||||  1    [O]    COG3175 Cytochrome oxidase assembly factor
-------------------|-------||-------------------||-----|---|||||--  1    [R]    COG3176 Putative hemolysin
-------------------------------------------------|--||||---|||||--  1    [R]    COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases
-------------------------------------------------|--|||----||||---  1    [S]    COG3184 Uncharacterized protein conserved in bacteria
--|---------------|-||----|---------------|||||-||-----||||||||---  1    [O]    COG3187 Heat shock protein
----||-----|--------------|||-----|-------|||-|--|-----|---||||---  1    [S]    COG3189 Uncharacterized conserved protein
----------||------|----------------|------|---|--|-----|---|-|||--  1    [R]    COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol
-------------||---------------------------|||-|--|---------||||---  1    [F]    COG3194 Ureidoglycolate hydrolase
---------------------|----|---------||-----------|-----|---|||||--  1    [S]    COG3195 Uncharacterized protein conserved in bacteria
--------------------------||||-------------------|------||||||||--  1    [E]    COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
------------------------------------------------||---|||---|||----  1    [P]    COG3213 Uncharacterized protein involved in response to NO
------------------|-----------------------------||---------||||---  1    [S]    COG3216 Uncharacterized protein conserved in bacteria
-------------------------------------------------|--|-----||||||--  1    [R]    COG3218 ABC-type uncharacterized transport system, auxiliary component
---------------------|-----------------------||-||-|---|-----|----  1    [E]    COG3232 5-carboxymethyl-2-hydroxymuconate isomerase
------------------------------------------|||||-||--|--|-----||---  1    [S]    COG3242 Uncharacterized protein conserved in bacteria
--|----------------|-------||--|--||------||||---|-----|----|||---  1    [S]    COG3247 Uncharacterized conserved protein
----||-----------------------------|||----|||||-----------|||||---  1    [S]    COG3254 Uncharacterized conserved protein
----------||------|------------------------------|---|||---|||----  1    [P]    COG3256 Nitric oxide reductase large subunit
---------------------|--------------------|||-|--|---------||||---  1    [R]    COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization
------------------|------------------------------|-----|--|--|----  1    [C]    COG3258 Cytochrome c
------------------|-----------------------|||||--|||---|---|||||--  1    [M]    COG3264 Small-conductance mechanosensitive channel
---|-----------|--|--------|||-------------------|-----------|----  1    [S]    COG3268 Uncharacterized conserved protein
------------------------------------------------||---|||||||||||--  1    [O]    COG3278 Cbb3-type cytochrome oxidase, subunit 1
--------------------|---------||||||||----|||||-||--|--|---|||||--  1    [K    T]    COG3279 Response regulator of the LytR/AlgR family
-------------------|----------|-----||----|-----||-----|---|||||--  1    [Q    K]    COG3284 Transcriptional activator of acetoin/glycerol metabolism
-----------------||||---------|--||-------|||||-||||||||||-|||||||  1    [M]    COG3307 Lipid A core - O-antigen ligase and related enzymes
------------------------------------------|||||-|---|--|----|||---  1    [K]    COG3311 Predicted transcriptional regulator
------------------------------------------|||||-||-----|----||||--  1    [R]    COG3313 Predicted Fe-S protein
-|-|----|-------|---------|-------||---------|------|--------|||--  1    [L]    COG3316 Transposase and inactivated derivatives
-------------------|------||||------|-----|||||--|-----|-----||---  1    [Q]    COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases
----------------|-------------------||------------------||||||||--  1    [S]    COG3334 Uncharacterized conserved protein
|-|---------------||----------|-----||-----------------|---|||||--  1    [S]    COG3339 Uncharacterized conserved protein
-----------------------------------|-|----|||||-|------------||---  1    [S]    COG3394 Uncharacterized protein conserved in bacteria
----------|--------------------------------------|---|||----||----  1    [P]    COG3420 Nitrous oxidase accessory protein
--|---------------------------------------||||---|-|-||----|-|||--  1    [S]    COG3422 Uncharacterized conserved protein
---|||----|||--------|-----||--------------------------|----|||---  1    [S]    COG3427 Uncharacterized conserved protein
---------------------------||-------|-----|||||-||-----------|----  1    [Q]    COG3433 Aryl carrier domain
--||||-----|----|-------|---------------------|------||------|----  1    [S]    COG3439 Uncharacterized conserved protein
---|--------------------------|--------|------|-----|--|||-|||||||  1    [U]    COG3451 Type IV secretory pathway, VirB4 components
----------------------------------------------------|||----|||||--  1    [S]    COG3453 Uncharacterized protein conserved in bacteria
-------------------|----------------------||||---|---------||||---  1    [P]    COG3454 Metal-dependent hydrolase involved in phosphonate metabolism
-----------------|------------|----|---------|--|----------||||---  1    [G]    COG3459 Cellobiose phosphorylase
|-|||--------------|||--------||-----|--------|------|||----|||---  1    [R]    COG3467 Predicted flavin-nucleotide-binding protein
--------------------|---|--------------------|-----|------|--|----  1    [P]    COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport
----------------|---|--------------------------------------|||||||  1    [S]    COG3494 Uncharacterized protein conserved in bacteria
-------------------|-|-----||------------------------------|||||--  1    [S]    COG3502 Uncharacterized protein conserved in bacteria
|-|-----|----------------------------------------|-----|---|||||--  1    [S]    COG3503 Predicted membrane protein
----------------------------------------------------|--|||-|||||||  1    [U]    COG3504 Type IV secretory pathway, VirB9 components
------------------------------------------------||---------||||---  1    [O]    COG3526 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---|||---||||---  1    [S]    COG3536 Uncharacterized protein conserved in bacteria
|-|-----|---------------------|----------------------------|-||---  1    [S]    COG3543 Uncharacterized conserved protein
------------------------------------------------||-----------|||--  1    [S]    COG3553 Uncharacterized protein conserved in bacteria
-------------|----------------||--||-------------|---||----|-|----  1    [R]    COG3560 Predicted oxidoreductase related to nitroreductase
---------------------------||--------|----------------------|||---  1    [S]    COG3564 Uncharacterized protein conserved in bacteria
--------------------------------||-|------|||-|--|--|--|---|||||--  1    [R]    COG3568 Metal-dependent hydrolase
---------------------------||----|------------------|------|||||--  1    [H]    COG3572 Gamma-glutamylcysteine synthetase
---------------------|-----||------------------------------|-||---  1    [R]    COG3573 Predicted oxidoreductase
-------------------------------------------------|---------|||||||  1    [R]    COG3577 Predicted aspartyl protease
--|----------------------------------------||-----|-----||---|----  1    [S]    COG3586 Uncharacterized conserved protein
--------------------------|----|------|-------------|--------|-|--  1    [S]    COG3600 Uncharacterized phage-associated protein
------------------------------------------|||||-||---------|||||--  1    [T]    COG3605 Signal transduction protein containing GAF and PtsI domains
|--|-----|--------------------------------------||---------||||---  1    [R]    COG3608 Predicted deacylase
-------------||-----|-----|||--------------------|-----|---|||||--  1    [E]    COG3616 Predicted amino acid aldolase or racemase
---------------------------------------------|---|-----|--|||||---  1    [R]    COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold
--|---------------|-|------||-||||-||------------|-----|---||||---  1    [S]    COG3619 Predicted membrane protein
--------------------------|---------------|||||--|||---|----|||---  1    [G]    COG3622 Hydroxypyruvate isomerase
-------------------|-------------|-----|-----||-||---|-------|-|--  1    [R]    COG3654 Prophage maintenance system killer protein
-------------------|-|-----||--------------|||--||--|--|---|||||--  1    [R]    COG3668 Plasmid stabilization system protein
--------------------|---|--------------------||---||-------||||---  1    [R]    COG3683 ABC-type uncharacterized transport system, periplasmic component
-------------------|-----------------------------|---|||---|-|-|--  1    [S]    COG3686 Predicted membrane protein
---------------------|--------------------|||--------------||||---  1    [S]    COG3698 Predicted periplasmic protein
----------------------------------------------------|------|||||-|  1    [U]    COG3702 Type IV secretory pathway, VirB3 components
-------------||---------------------|-----|||----------|---|||||--  1    [P]    COG3703 Uncharacterized protein involved in cation transport
----------------------------------------------------|------|||||||  1    [U]    COG3704 Type IV secretory pathway, VirB6 components
----------------|-||-|--------||---|||-----------|---|||---|||||--  1    [E]    COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis
-----------------|||-----|-----------|-----------|--------||||||||  1    [T]    COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain
------------------------------------------||||---|---------||||---  1    [P]    COG3709 Uncharacterized component of phosphonate metabolism
---------------------------||-------------|||||-|------|-----|||--  1    [S]    COG3714 Predicted membrane protein
--------------------------|--------|||-------||--------|---|||||--  1    [G]    COG3718 Uncharacterized enzyme involved in inositol metabolism
------------------------------------------|||-|---||-------|||||--  1    [J]    COG3719 Ribonuclease I
------------------------------------------|---|--------|---|||||--  1    [G]    COG3734 2-keto-3-deoxy-galactonokinase
------------------------|-----|-----------|||||-|----------|||||--  1    [S]    COG3735 Uncharacterized protein conserved in bacteria
----------------------------------------------------|---||-||||-||  1    [U]    COG3736 Type IV secretory pathway, component VirB8
----------------------------------------------------||||---|||||--  1    [S]    COG3737 Uncharacterized conserved protein
-------------------------------------------------|-----|---|||||--  1    [S]    COG3748 Predicted membrane protein
-------------------------------------------------|-----|---|||||--  1    [S]    COG3749 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG3750 Uncharacterized protein conserved in bacteria
------------------------------------------|||----|-----|----|||---  1    [S]    COG3753 Uncharacterized protein conserved in bacteria
--------------------|-----------|---------||||---|-----|---||||---  1    [S]    COG3758 Uncharacterized protein conserved in bacteria
-------------------------------|-----------------|---------|||||--  1    [S]    COG3760 Uncharacterized conserved protein
-----------------------------------------------------------|||||||  1    [C]    COG3761 NADH:ubiquinone oxidoreductase 17.2 kD subunit
------------------------|--------------------------|---|-----|||--  1    [S]    COG3762 Predicted membrane protein
------------------------------------------|||||---||-------||||---  1    [S]    COG3768 Predicted membrane protein
------------------------------------------|||||---||-------||||---  1    [M]    COG3770 Murein endopeptidase
-------------||----------------------------------|-----------|-|--  1    [S]    COG3777 Uncharacterized conserved protein
------------------------------------------|||||------------|||||--  1    [S]    COG3785 Uncharacterized conserved protein
---------------------------||||----|-----------------------|||||--  1    [S]    COG3786 Uncharacterized protein conserved in bacteria
--------------|-------------------------------|--|-----|---|||||--  1    [S]    COG3791 Uncharacterized conserved protein
--||--------------||---------------------------------------||||---  1    [C]    COG3794 Plastocyanin
-------------------------------------------------|---------|||||--  1    [S]    COG3802 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|||||--  1    [S]    COG3803 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG3807 Uncharacterized protein conserved in bacteria
--|-------|------|--|--------------------------------------|||||--  1    [C]    COG3808 Inorganic pyrophosphatase
-----------------------------------------------------------|||||||  1    [S]    COG3814 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------|||||--  1    [S]    COG3816 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG3820 Uncharacterized protein conserved in bacteria
------------------------------------|------|||-----|---------||---  1    [R]    COG3822 ABC-type sugar transport system, auxiliary component
--------------------------|||-------------------------------||||--  1    [S]    COG3824 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG3827 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-------||||---  1    [H]    COG3840 ABC-type thiamine transport system, ATPase component
------------------------------------------|||||-||--|--|---|||||--  1    [T]    COG3852 Signal transduction histidine kinase, nitrogen specific
---------------------------------------------||--------|---|||||--  1    [S]    COG3892 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|||||||||--  1    [L]    COG3893 Inactivated superfamily I helicase
------------------|-----------------------|||||--|-----|---|||----  1    [R]    COG3895 Predicted periplasmic protein
-------------||----------------------------------|---------|||||--  1    [R]    COG3897 Predicted methyltransferase
-----------------------------------------------------------|||||--  1    [S]    COG3898 Uncharacterized membrane-bound protein
-------------------------------------------------|---|||----||----  1    [K]    COG3901 Regulator of nitric oxide reductase transcription
-----------------------------------------------------------|||||--  1    [S]    COG3908 Uncharacterized protein conserved in bacteria
-------------------------------------------------|--|--|---|||----  1    [U]    COG3946 Type IV secretory pathway, VirJ component
--------------|---||----------||-----------------|----------|||---  1    [G]    COG3957 Phosphoketolase
--------------------------|--------|||-------||--------|---|||||--  1    [E]    COG3962 Acetolactate synthase
-------------------------------------|-------|-------------||||---  1    [I]    COG3963 Phospholipid N-methyltransferase
---------------------|-----||-------------|||||--|-|---|---|-|-|--  1    [Q]    COG3971 2-keto-4-pentenoate hydratase
-------------------|---------------|-|---------------------|-||---  1    [E]    COG4091 Predicted homoserine dehydrogenase
-----------------------------------------------------------|||||--  1    [S]    COG4093 Uncharacterized protein conserved in bacteria
----------------|-------------------------||||||||||||||||||||||||  1    [R]    COG4105 DNA uptake lipoprotein
---------------------|-----||-------------||||---|---------||||---  1    [R]    COG4106 Trans-aconitate methyltransferase
------------------||-|----|---||||||------||||||||||||||---|||||--  1    [J]    COG4108 Peptide chain release factor RF-3
-------------------|----------------------|||-|--|-----|-----||---  1    [C]    COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein)
--------------------|-----|-----||--------------||-----|---||||-||  1    [R]    COG4120 ABC-type uncharacterized transport system, permease component
----------------||--|---------||||||||||--|||||-|-||----||||||||--  1    [R]    COG4123 Predicted O-methyltransferase
------------------------------|-----|----------------------||||---  1    [G]    COG4124 Beta-mannanase
--------------------------|||-|-||||||---------------------|-|----  1    [S]    COG4129 Predicted membrane protein
-------------------------------------------------|--------|||||---  1    [R]    COG4132 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-|||||------|||||||  1    [O]    COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component
------------------------------------------||||--|----------|||----  1    [R]    COG4134 ABC-type uncharacterized transport system, periplasmic component
---|--||--|----------|--|-----------------|||||-|-||-||----||||---  1    [H]    COG4143 ABC-type thiamine transport system, periplasmic component
----------------------------------|-------|||||-||||-------||||---  1    [P]    COG4148 ABC-type molybdate transport system, ATPase component
--|---------|---|-||------|||-----||||----|||||-||||---|||||||||--  1    [P]    COG4149 ABC-type molybdate transport system, permease component
------------------------------------------|||||-|----------|-||---  1    [P]    COG4150 ABC-type sulfate transport system, periplasmic component
---------------------------------|--------|||-|---|--------||||---  1    [G]    COG4154 Fucose dissimilation pathway protein FucU
------------------------------------------|||||-||-----|||-||||---  1    [R]    COG4174 ABC-type uncharacterized transport system, permease component
------------------------------------------|||||-||-----|-----|-|--  1    [H]    COG4206 Outer membrane cobalamin receptor protein
---|---------||---||||----|||--|-|||------|||-|-||||||||||||||----  1    [R]    COG4221 Short-chain alcohol dehydrogenase of unknown specificity
-----------------------------------------------------------|||||--  1    [S]    COG4223 Uncharacterized protein conserved in bacteria
------------------------------------------|||||--|-|-|||---|||||--  1    [C]    COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase
----------------------||----------------------|------------|||||--  1    [O    C]    COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis
------------------------------------------|||||--||||------|||||--  1    [O]    COG4235 Cytochrome c biogenesis factor
-------------------------|----------------|||||-||-----|||-||||---  1    [R]    COG4239 ABC-type uncharacterized transport system, permease component
---------------------|---------------------------------|---||||---  1    [S]    COG4291 Predicted membrane protein
-----------|------------------|------------------------|---|||----  1    [S]    COG4309 Uncharacterized conserved protein
------------------------------|---------------------------||-|----  1    [R]    COG4310 Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain
-------------------------------------------------|-----|---||||---  1    [E]    COG4311 Sarcosine oxidase delta subunit
-------------------------------------------------|---|||----||----  1    [C]    COG4314 Predicted lipoprotein involved in nitrous oxide reduction
----------------------------------------------------||||---|||-|-|  1    [S]    COG4391 Uncharacterized protein conserved in bacteria
----------------------------------|----------|---|-----------|----  1    [E]    COG4413 Urea transporter
------------------||---------------------------------------||||---  1    [E]    COG4448 L-asparaginase II
-------------------------------------------------------|---||||-||  1    [M]    COG4520 Surface antigen
--------------------------|||-----|-------|||--------------||||---  1    [S]    COG4529 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG4530 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||||-------|||----  1    [P]    COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin
----------------------------------|-------|||||-||||---|----||||||  1    [P]    COG4536 Putative Mg2+ and Co2+ transporter CorB
-------------------------------------------------------|---||||---  1    [S]    COG4541 Predicted membrane protein
-----------------------------------------------------------|||||--  1    [S]    COG4544 Uncharacterized conserved protein
---------------------------------------------|-------------|||||--  1    [H]    COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)
----------------------------------|-|------------|---------|||----  1    [P]    COG4548 Nitric oxide reductase activation protein
-----------------------------------||----------------------||||---  1    [S]    COG4549 Uncharacterized protein conserved in bacteria
------------------------------------------------|------|---|-|----  1    [T]    COG4564 Signal transduction histidine kinase
----------------------------------------------|--|-|---|---|||||--  1    [T]    COG4566 Response regulator
-------------------------------------------------|--|--|---|||||--  1    [T    K]    COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
-------------------------------------------------|-----|---||||---  1    [E]    COG4583 Sarcosine oxidase gamma subunit
--|-------------|---||--||----|-----------||||||||||||||||||||||||  1    [M]    COG4591 ABC-type transport system, involved in lipoprotein release, permease component
-------------------|----------------------|||---|----------||||---  1    [E]    COG4597 ABC-type amino acid transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  1    [P]    COG4604 ABC-type enterochelin transport system, ATPase component
--------------------------|------||-||-------|--|----||---||-|----  1    [P]    COG4605 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  1    [P]    COG4606 ABC-type enterochelin transport system, permease component
--------------------------|------||-||-------|--|----||---||-|----  1    [P]    COG4607 ABC-type enterochelin transport system, periplasmic component
---------------------|---------------------------|-----|---||||---  1    [F]    COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A
---------------------|---------------------------|-----|---|||||--  1    [F]    COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B
-----------------|||------|||-------------||||---|-----|---|||||--  1    [P    R]    COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
------------------------------------------------|----------||||---  1    [S]    COG4645 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG4649 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||--|--|----|||---  1    [P]    COG4651 Kef-type K+ transport system, predicted NAD-binding component
------------------||----------------------------|----------||||---  1    [Q]    COG4663 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component
------------------||----------------------------|----------||||---  1    [Q]    COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component
------------------||----------------------------|----------||||---  1    [Q]    COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component
---|----|---|--------|---------------|----------||-|--------||----  1    [R]    COG4666 TRAP-type uncharacterized transport system, fused permease components
---||-----|-|-------|-------------||-|----|||-|--------|----|||---  1    [I]    COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase
------------------------------|||---------|||----------|---|-|||--  1    [S]    COG4695 Phage-related protein
-------------||------------------------------|--------------|||---  1    [S]    COG4702 Uncharacterized conserved protein
------------------------||-----------------------------|||-|||||--  1    [S]    COG4731 Uncharacterized protein conserved in bacteria
--------------------------|----------------------|-----|-----|----  1    [R]    COG4757 Predicted alpha/beta hydrolase
-------------------------------------------------|---------||||---  1    [S]    COG4764 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG4765 Uncharacterized protein conserved in bacteria
-------------||-||||||||||----------------||||||||||||||||||||||||  1    [M]    COG4775 Outer membrane protein/protective antigen OMA87
-------------------|-----------------------------------|---||||---  1    [S]    COG4782 Uncharacterized protein conserved in bacteria
----------------|-||----------------------|||||-||--|--|-----|||--  1    [R]    COG4783 Putative Zn-dependent protease, contains TPR repeats
-------------------------------------------------|---------||||---  1    [R]    COG4784 Putative Zn-dependent protease
--|---------------|----------------------------------------||||---  1    [S]    COG4803 Predicted membrane protein
-----------------------------------|-|---------------------||||---  1    [G]    COG4813 Trehalose utilization protein
-----------------------------------|-|-----------------------|----  1    [R]    COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain
--|----------------|-----------------------------------------||---  1    [S]    COG4872 Predicted membrane protein
----------------------------------------------------|--|-----|----  1    [S]    COG4875 Uncharacterized protein conserved in bacteria with a cystatin-like fold
----------------------------------------------|-|------------|----  1    [S]    COG4890 Predicted outer membrane lipoprotein
----------------------------------------------|--|-----------|----  1    [S]    COG4893 Uncharacterized protein conserved in bacteria
------------------|------------------------------------|-----|----  1    [S]    COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain
--|----------------||------------------------|-----|---------|----  1    [S]    COG4929 Uncharacterized membrane-anchored protein
---------||-|-------------------------|----------------------|----  1    [S]    COG4933 Uncharacterized conserved protein
--------------------|---------------------|||||-|||||||----|||||--  1    [D]    COG4942 Membrane-bound metallopeptidase
-----------------------------------------------------------|||||--  1    [S]    COG4944 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [K]    COG4957 Predicted transcriptional regulator
--------------------|---|-|||||---||||----|||||-||||||||---|||||||  1    [L]    COG4974 Site-specific recombinase XerD
-----------------------------------------------------------|||||--  1    [R]    COG4976 Predicted methyltransferase (contains TPR repeat)
-------------------------------|--||||----|||||-|-||-------|-|-|--  1    [C    O]    COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components
--------------------|-----|||--||-||||----|||||-|-||-------|-|-|--  1    [C    O]    COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components
----------------|------------------------------------|||---|||||||  1    [T]    COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
----------------|-------||----------------|||||-||||||||---|||||||  1    [M]    COG5009 Membrane carboxypeptidase/penicillin-binding protein
--------------|----------------------------------------|-----|-|--  1    [F]    COG5042 Purine nucleoside permease
-------------||------------------------------|---------|---|||||||  1    [O]    COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components
--|-----------------|-----------------------------|--||------|----  1    [P]    COG5266 ABC-type Co2+ transport system, periplasmic component
-------------------------------------------||||--|-----|---|-|----  1    [S]    COG5281 Phage-related minor tail protein
-----------------------------------------------------------|||||--  1    [S]    COG5317 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---|||||--  1    [S]    COG5319 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5321 Uncharacterized protein conserved in bacteria
--|--------------------------------------------------------|-|-|--  1    [S]    COG5323 Uncharacterized conserved protein
-----------------------------------------------------------|||||--  1    [S]    COG5328 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5330 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG5336 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5338 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------||||---  1    [S]    COG5345 Uncharacterized protein conserved in bacteria
-----------------------------------|-----------------------||||---  1    [R]    COG5350 Predicted protein tyrosine phosphatase
------------------------------------------------------------||||--  1    [S]    COG5352 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5360 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||||  1    [S]    COG5375 Uncharacterized protein conserved in bacteria
---------------------------||-------------|||||-------------||----  1    [S]    COG5383 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5385 Uncharacterized protein conserved in bacteria
-------------||--------------------------------------------|||-|--  1    [O]    COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase
-----------------------------------------------------------|||||--  1    [S]    COG5388 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|||||--  1    [S]    COG5389 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------|-|||--  1    [S]    COG5395 Predicted membrane protein
-----------------------------------------------------------|||||--  1    [S]    COG5400 Uncharacterized protein conserved in bacteria
--------|--------------------------------------------------||||---  1    [S]    COG5402 Uncharacterized conserved protein
----------------||-------|--------||||----|||||||||||--|||||||||||  1    [O]    COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit
-----------------------------------------------------------|||||--  1    [E]    COG5425 Usg protein, probable subunit of phosphoribosylanthranilate isomerase
-------------------------------------------------------|---|||||--  1    [S]    COG5429 Uncharacterized secreted protein
--------|---------------------------------------------------|||---  1    [S]    COG5436 Predicted integral membrane protein
-----------------------------------|-|---------------------|-|-|--  1    [S]    COG5437 Predicted secreted protein
---------------------------------------------|--------------|||---  1    [S]    COG5441 Uncharacterized conserved protein
-----------------------------------------------------------|||||--  1    [N]    COG5442 Flagellar biosynthesis regulator FlaF
-----------------------------------------------------------|||||--  1    [N]    COG5443 Flagellar biosynthesis regulator FlbT
-------------------------------------------------|---------|-||---  1    [S]    COG5446 Predicted integral membrane protein
-----------------------------------------------------------|||||--  1    [S]    COG5447 Uncharacterized conserved protein
-----------------------------------------------------------|-|-|-|  1    [S]    COG5448 Uncharacterized conserved protein
-----------------------------------------------------------|-|-|-|  1    [S]    COG5449 Uncharacterized conserved protein
-----------------------------------------------------------|||||--  1    [S]    COG5451 Predicted secreted protein
-----------------------------------------------------------|||||--  1    [S]    COG5452 Uncharacterized conserved protein
------------------------------------------------|----------||||---  1    [S]    COG5453 Uncharacterized conserved protein
-----------------------------------------------------------|||||--  1    [S]    COG5454 Predicted secreted protein
------------------------------------------|||-|--------|---|||||--  1    [S]    COG5455 Predicted integral membrane protein
-----------------------------------------------------------|||||--  1    [P]    COG5456 Predicted integral membrane protein linked to a cation pump
------------------------------------------|||-|--|---------||||---  1    [S]    COG5457 Uncharacterized conserved small protein
-----------------------------------------------------------|||||--  1    [S]    COG5458 Uncharacterized conserved protein
-------------||----------------------------------------------||---  1    [J]    COG5459 Predicted rRNA methylase
-----------------------------------------------------------||||-||  1    [S]    COG5462 Predicted secreted (periplasmic) protein
----------------------||-----------------------------------|||||--  1    [S]    COG5465 Uncharacterized conserved protein
------------------------------------------------------------||||--  1    [S]    COG5467 Uncharacterized conserved protein
-----------------------------------------------------------|||||--  1    [S]    COG5468 Predicted secreted (periplasmic) protein
--|----------------------------------------------------|---||||---  1    [S]    COG5470 Uncharacterized conserved protein
-------------------------------------------------------|---||||---  1    [S]    COG5476 Uncharacterized conserved protein
------------------|----------------------------------------||||---  1    [S]    COG5480 Predicted integral membrane protein
-----------------------------------------------------------|||||--  1    [S]    COG5481 Uncharacterized conserved small protein containing a coiled-coil domain
-------------------------------------------|-||--|-----|---||||---  1    [S]    COG5487 Small integral membrane protein
-------------------------------------------------------|---|||||--  1    [S]    COG5488 Integral membrane protein
----------------------------------------------------|-------||||||  1    [S]    COG5508 Uncharacterized conserved small protein
------------------------------------------------------------||||--  1    [S]    COG5509 Uncharacterized small protein containing a coiled-coil domain
-------------------------------------------|--|--------|-----|-|-|  1    [S]    COG5510 Predicted small secreted protein
-------------------------------------------------------|-----||---  1    [S]    COG5514 Uncharacterized conserved protein
------------------------------|-----------------------------|||---  1    [S]    COG5515 Uncharacterized conserved small protein
------------------------------------------||-||--|-----------|----  1    [N]    COG5567 Predicted small periplasmic lipoprotein
-----------------------------------------------------------|||||--  1    [S]    COG5568 Uncharacterized small protein
------------------------------------------------------------||||--  1    [S]    COG5570 Uncharacterized small protein
---------------------------||-------------------------------|||---  1    [S]    COG5586 Uncharacterized conserved protein
----------------------------------------------------|--------||---  1    [S]    COG5587 Uncharacterized conserved protein
---------------------------------------------|--------------|||---  1    [R]    COG5618 Predicted periplasmic lipoprotein
-------------------------------------------------------|-----||---  1    [K]    COG5631 Predicted transcription regulator, contains HTH domain (MarR family)
------------------|----------------------------------------||||---  1    [O]    COG5661 Predicted secreted Zn-dependent protease
-----------------------------------------------------------||||---  1    [O]    COG5664 Predicted secreted Zn-dependent protease
|||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|---  0    [F]    COG0005 Purine nucleoside phosphorylase
||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|---  0    [P]    COG0025 NhaP-type Na+/H+ and K+/H+ antiporters
---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||--  0    [H]    COG0029 Aspartate oxidase
-||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|---  0    [G]    COG0058 Glucan phosphorylase
||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||--  0    [E]    COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase
||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||--  0    [H]    COG0157 Nicotinate-nucleotide pyrophosphorylase
|||-|||||||||||-|||||---------------|------------|--|-------|-|---  0    [J]    COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family
-------------||||||||||||||||||||||||||||||||||||-|||------||-|---  0    [G]    COG0205 6-phosphofructokinase
-||---|||--------|---|-----||-||-||||||||||||-|-|------|---||-|---  0    [F]    COG0213 Thymidine phosphorylase
-|--||-------|||--|-|------||-|-----------|||||||||||||||||---||--  0    [E]    COG0241 Histidinol phosphatase and related phosphatases
||----||-||||-|---||------|---|-||--||||--|||-|-|-|-||||||--|-||--  0    [L]    COG0270 Site-specific DNA methylase
|--|||----|-|---||||-|--|-|||||||||||||||||||||-|-||-------||-|---  0    [F]    COG0274 Deoxyribose-phosphate aldolase
-|--||----------|-|-|------||-|-----------||||||||||-||-|||---|---  0    [G]    COG0279 Phosphoheptose isomerase
---|------|-|||--|---|---|-||||||||||||||||||||-|-||-------||-||--  0    [F]    COG0295 Cytidine deaminase
--|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|---  0    [G]    COG0296 1,4-alpha-glucan branching enzyme
-|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|---  0    [G]    COG0297 Glycogen synthase
--|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||--  0    [R]    COG0300 Short-chain dehydrogenases of various substrate specificities
||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|---  0    [P]    COG0306 Phosphate/sulphate permeases
-------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-||  0    [O]    COG0326 Molecular chaperone, HSP90 family
--|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||--  0    [G]    COG0366 Glycosidases
|||||||||||-||||----------||||||---|||----|||||-||--|-------|-|---  0    [E]    COG0367 Asparagine synthase (glutamine-hydrolyzing)
|||||||||||||-|--|||----------||||-|||----|||||-------------|-----  0    [C]    COG0371 Glycerol dehydrogenase and related enzymes
--||----|----|----|--------||--------|----|||||-|---|--|---||-||--  0    [P]    COG0376 Catalase (peroxidase I)
||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||--  0    [H]    COG0379 Quinolinate synthase
|---||----|--|||--|-------||||------------|||-|--------|----|-|---  0    [G]    COG0380 Trehalose-6-phosphate synthase
-------------||---||-|----||||------|-----|||||------------||-|---  0    [P]    COG0387 Ca2+/H+ antiporter
-------------||---||------|----------|----|||-|-||--|--|---||--|--  0    [S]    COG0397 Uncharacterized conserved protein
--||---------||---||------|||-||||||||----|||---|-----------|--|--  0    [S]    COG0398 Uncharacterized conserved protein
-------------||---||----------------------|||-|--|---------|------  0    [S]    COG0401 Uncharacterized homolog of Blt101
----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||--  0    [E]    COG0405 Gamma-glutamyltransferase
--|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||--  0    [Q]    COG0412 Dienelactone hydrolase and related enzymes
|-||-------|-|----||------|-----|-||------||||||||----|----|--||--  0    [L]    COG0415 Deoxyribodipyrimidine photolyase
-------------||---|-----------------------||||||||---||||||||-----  0    [F]    COG0418 Dihydroorotase
||||||||||||||||||||||--||||||||--||||----|||||-||----------|-----  0    [L]    COG0420 DNA repair exonuclease
-|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|---  0    [E]    COG0421 Spermidine synthase
||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||--  0    [H]    COG0422 Thiamine biosynthesis protein ThiC
||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|-----  0    [P]    COG0428 Predicted divalent heavy-metal cations transporter
---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||--  0    [R]    COG0431 Predicted flavoprotein
|||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||-----  0    [S]    COG0432 Uncharacterized conserved protein
-|-|--|||||-|-----||----------------------|---|------------|--|---  0    [R]    COG0434 Predicted TIM-barrel enzyme
--||---||-|||---|-------------------------|||||-||||---|--|-|-|---  0    [C]    COG0437 Fe-S-cluster-containing hydrogenase components 1
-----------------|||||||--||||||-|--||----|||||-|-||-------||-|---  0    [G]    COG0448 ADP-glucose pyrophosphorylase
||||||||||||||||--||-|----||||------||-----------|-----|--|||-|---  0    [O]    COG0464 ATPases of the AAA+ class
||||||||||||||--||||---------------------------------------||-|---  0    [T]    COG0467 RecA-superfamily ATPases implicated in signal transduction
-------------||-----|---|------|||||||-||||||||-|-|-----------|---  0    [M]    COG0510 Predicted choline kinase involved in LPS biosynthesis
--|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||--  0    [L]    COG0514 Superfamily II DNA helicase
---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|---  0    [R    T    K    L]    COG0515 Serine/threonine protein kinase
||||||||||||-||-|||-----||-----------|----|||||-|--|--------|-----  0    [P]    COG0530 Ca2+/Na+ antiporter
|||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|---  0    [R]    COG0535 Predicted Fe-S oxidoreductases
|||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----||  0    [H    C]    COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases
---|||||--|-|-----|------------||||-----|-|||-|--||---------|-----  0    [E]    COG0549 Carbamate kinase
--||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|-----  0    [K    L]    COG0553 Superfamily II DNA/RNA helicases, SNF2 family
|-||||||||||||||-||||||||||||||||||||||||||||||||-||-|||---||-|---  0    [R]    COG0561 Predicted hydrolases of the HAD superfamily
|--------------------|----|||||---------|||---|-----------||------  0    [M]    COG0562 UDP-galactopyranose mutase
|-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-||||  0    [P]    COG0607 Rhodanese-related sulfurtransferase
|||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||--  0    [E]    COG0620 Methionine synthase II (cobalamin-independent)
-----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|---  0    [T]    COG0631 Serine/threonine protein phosphatase
-|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||--  0    [T]    COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
|||-----|--|-----|||----------|-----------|||||---||--------|-----  0    [R]    COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  0    [N    T]    COG0643 Chemotaxis protein histidine kinase and related kinases
---|------------|-||-|-----||--------------------|----------|-||--  0    [R]    COG0645 Predicted kinase
--|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||--  0    [I]    COG0657 Esterase/lipase
--|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|---  0    [P]    COG0659 Sulfate permease and related transporters (MFS superfamily)
----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-||||  0    [R]    COG0666 FOG: Ankyrin repeat
---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||--  0    [C]    COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)
||----||--|------|------------|---|-------|||||-||-||--|---||-|---  0    [M]    COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase
|||-----||---|-------|----||||-------|----|||||-||||---|---||-|---  0    [H]    COG0684 Demethylmenaquinone methyltransferase
------------------||-|-----|||-|--||||----------|-------||--|-||--  0    [E]    COG0686 Alanine dehydrogenase
-------------|||----||||-|||||-||||||||||||||||||||||||||||||-----  0    [L]    COG0692 Uracil DNA glycosylase
--||-----------|--||----------|---|||||||||||||-||------||||------  0    [G]    COG0696 Phosphoglyceromutase
-|-------|||----|-------------------------|||||--|||------|-|-----  0    [E]    COG0709 Selenophosphate synthase
-------------||----|-|----|----|-|--------||||||||||||||------||--  0    [E]    COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase
-|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|---  0    [R]    COG0727 Predicted Fe-S-cluster oxidoreductase
|--|----|----||-|||--|--|-|---|||-||||-|--|||||-|-||---|||-||-|---  0    [F]    COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases
----------------|||||||||-|||||----|||----|||||||||||||||||||--|--  0    [I]    COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase
------------------||----------------------------||||----|||||-|---  0    [P]    COG0748 Putative heme iron utilization protein
------------------|-----------------------|||||---|-----||||---|--  0    [E]    COG0754 Glutathionylspermidine synthase
-----------------||||-||||||||||||||||----|||||-||||---||||||-||--  0    [S]    COG0762 Predicted integral membrane protein
|-|---|-|----|---|||------|||-|----||--------------|--|----|------  0    [P]    COG0798 Arsenite efflux pump ACR3 and related permeases
|-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-||  0    [P]    COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin
-----------|--------||--|------||||||-|||||||||||-||----||----|---  0    [F]    COG0813 Purine-nucleoside phosphorylase
-|-------------------------|||||||||||------------|-----||-|--|---  0    [L]    COG0827 Adenine-specific DNA methylase
--||--|||--------|||----||----|----|||----|||||-||--|--||||||-||--  0    [N    T]    COG0835 Chemotaxis signal transduction protein
--||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||--  0    [N    T]    COG0840 Methyl-accepting chemotaxis protein
----------------||||-|----|||||---||||----|||||--|--||||||||--||--  0    [H]    COG0853 Aspartate 1-decarboxylase
----------------|-|||---------------------|||||-|||||||||||---||--  0    [M]    COG0859 ADP-heptose:LPS heptosyltransferase
|||||||||||||---|||||---|--||-||--||-|----|||||-|------||||---||--  0    [C]    COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit
-----------------|---|--------||||||||-|--|||||||-------||-||-|---  0    [G]    COG1015 Phosphopentomutase
-------------||-|----|----|-------|-||----|||||-||--|--|--|-|-----  0    [C]    COG1017 Hemoglobin-like flavoprotein
---|------------|----|-----||--|----||---------------------|--|---  0    [G]    COG1023 Predicted 6-phosphogluconate dehydrogenase
--|-|||||-|-|---|-----------------|-||-----------|-----|----|-|---  0    [O]    COG1030 Membrane-bound serine protease (ClpP class)
|||-|||||||||----|||||-----||-||-----|----|||-|-||------------|---  0    [C]    COG1032 Fe-S oxidoreductase
|||-----||--------||----------------------------------------|-----  0    [C]    COG1035 Coenzyme F420-reducing hydrogenase, beta subunit
-|||||||||||-------|----------------------|||||-||---||-----|-|---  0    [C]    COG1042 Acyl-CoA synthetase (NDP forming)
------------------||----------------------|||||-||-|||||||||------  0    [C]    COG1049 Aconitase B
----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|---  0    [P]    COG1055 Na+/H+ antiporter NhaD and related arsenite permeases
--|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||--  0    [E    R]    COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
--------------------||||-||---||||||||-|||||||||||||||||------||--  0    [G]    COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)
|-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||--  0    [M]    COG1088 dTDP-D-glucose 4,6-dehydratase
|-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-||||  0    [M]    COG1091 dTDP-4-dehydrorhamnose reductase
|||||||||||||||||-||-|----------------------------------------|---  0    [R]    COG1100 GTPase SAR1 and related small G proteins
|||-|----|-|------|||-----||||----|-------|||||-|------|||-||-|---  0    [R]    COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase
|||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|---  0    [C]    COG1145 Ferredoxin
--|-------------|||||----||||||||||||||||||||||-||||||||------|---  0    [R]    COG1162 Predicted GTPases
-------------------|----------||--||||-||||||||--||----|---||-|---  0    [I]    COG1182 Acyl carrier protein phosphodiesterase
--|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||-----  0    [J]    COG1190 Lysyl-tRNA synthetase (class II)
|||||||||||||||||-------------------------|----------------||-----  0    [R]    COG1204 Superfamily II helicase
|||---||||||-||----|-|----|||-------||-----||---------------|-----  0    [R]    COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
|-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||--  0    [M]    COG1209 dTDP-glucose pyrophosphorylase
|-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||--  0    [R]    COG1216 Predicted glycosyltransferases
------------------||-|----|||-------|------------|-----|------||--  0    [E]    COG1231 Monoamine oxidase
||||-------||-----||-|----|||-----||-|-----------------|------||--  0    [Q]    COG1233 Phytoene dehydrogenase and related proteins
||||||||||||||||-|||-|||||||||||||||||----|||-|----|---|------||--  0    [R]    COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
-||||||-|-||||||--||-|--------------------------||-----|---||-||--  0    [J]    COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing
--|-------------|----------||-|---|-||----|||||--|-----|---||-||--  0    [C]    COG1251 NAD(P)H-nitrite reductase
-||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|---  0    [C]    COG1254 Acylphosphatases
|-|---|||-||||--||--------||||------------------------------|-----  0    [I]    COG1260 Myo-inositol-1-phosphate synthase
|-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||--  0    [R]    COG1266 Predicted metal-dependent membrane protease
--------|------------------||-------||-----------|---------||-|---  0    [S]    COG1273 Uncharacterized conserved protein
----------------|----|-------------|||----|||||--------|----|-|---  0    [P]    COG1276 Putative copper export protein
---|--------------------|-|||-----||||----|||||-||||-||-----|-----  0    [M]    COG1292 Choline-glycine betaine transporter
|||---||||--|-----||-------||-|---|-||-----------|------------||--  0    [S]    COG1300 Uncharacterized membrane protein
--||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-||||  0    [C]    COG1301 Na+/H+-dicarboxylate symporters
|-|---||||||----||||-|-----||||----|||-----------||||--|---||-||--  0    [E]    COG1305 Transglutaminase-like enzymes, putative cysteine proteases
-----------------|----||||----|-----||----||||||||-----||||---|---  0    [N    U]    COG1317 Flagellar biosynthesis/type III secretory pathway protein
----------|||--------|--||-||-------||----|||----|-----|---||-|---  0    [C]    COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs
|||||||||||||----|---||||-||||||||||||----|||-|-----|---------|---  0    [K]    COG1321 Mn-dependent transcriptional regulator
|||------|--------|||---------|-----------------------------|-|---  0    [P]    COG1348 Nitrogenase subunit NifH (ATPase)
--||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||--  0    [N    T]    COG1352 Methylase of chemotaxis methyl-accepting proteins
|||-|||||||||||-||--------------------------------------------|---  0    [R]    COG1355 Predicted dioxygenase
--||--------------||-|--|-|||-||---|||----|||||--|-|-------||-||||  0    [S]    COG1357 Uncharacterized low-complexity proteins
--||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||--  0    [S]    COG1359 Uncharacterized conserved protein
||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|-----  0    [G]    COG1363 Cellulase M and related proteins
-----------------||||||||--||-|---||||----------||---------||--|--  0    [T]    COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
-----------------|------------|||-|||-----|||-|-||||-||-|||||-|---  0    [M]    COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
-||-|-||--||-----|--|------||----|-|--------------|-----|||---|--|  0    [R]    COG1373 Predicted ATPase (AAA+ superfamily)
|||-||||||---||-||--||-----||-||--||||----|||||-|-----------|-----  0    [E    R]    COG1387 Histidinol phosphatase and related hydrolases of the PHP family
|||---|||--|-----|---|||------|---|||-----------||||---|---||-|---  0    [P]    COG1392 Phosphate transport regulator (distant homolog of PhoU)
-||-----|-------|--|-|--------|--|--------|||-|---------------|---  0    [O]    COG1397 ADP-ribosylglycohydrolase
--||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|---  0    [O]    COG1404 Subtilisin-like serine proteases
|-|-------|-----|--|-|||--||||||---|||----|------------||||-|-|---  0    [R]    COG1408 Predicted phosphohydrolases
|-||---------|||--||--||||--------|-||----||-----|------------|---  0    [C]    COG1413 FOG: HEAT repeat
|---|||||||||-----------------------------------------------|-|---  0    [S]    COG1415 Uncharacterized conserved protein
|--|||--|-------|----|---------------------------------|------|---  0    [S]    COG1416 Uncharacterized conserved protein
||||||||||------||--||--||----|||||||||-|||||-|---------|||||-----  0    [R]    COG1418 Predicted HD superfamily hydrolase
---||-----|----|-|---|---|----|||||||||||||||||-|-||-------||-|---  0    [F]    COG1435 Thymidine kinase
---------------------------------|--|-----|||-|---||----||--|---||  0    [M]    COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases
---|||||--||--|---||----------------------|||-|-|------|---|---|--  0    [E]    COG1446 Asparaginase
-------------||-----|-||------------------|||||-||||||||----|-|---  0    [E]    COG1448 Aspartate/tyrosine/aromatic aminotransferase
----------------|---|-||------------------|||||-||--|--|--|---||--  0    [N    U]    COG1450 Type II secretory pathway, component PulD
----------------||||||||------||||||||----|||||-||||||||------||--  0    [N    U]    COG1459 Type II secretory pathway, component PulF
------||||--|----|------------------------------------------|-----  0    [R]    COG1483 Predicted ATPase (AAA+ superfamily)
--|-------------|----------||-|||||||||---||||||-------|---||-|---  0    [L]    COG1484 DNA replication protein
-----------------|------------|----|||----|||||-|----------||-|---  0    [G]    COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
-||---|||-||------||-|-----||-----------------|---|-|--|---||-||-|  0    [R]    COG1487 Predicted nucleic acid-binding protein, contains PIN domain
----||----||-||--|-|----------||-|-|-|----|||||--------|---|---|--  0    [G]    COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
------||-----------|-|----|||------------------------||-------||||  0    [E]    COG1505 Serine proteases of the peptidase family S9A
---|||||--|||||---|-||------------|-||-----------|--|------|---|-|  0    [E]    COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases
-||-------------||--||--|-----------||----|||||-|-|||------||-||--  0    [E]    COG1509 Lysine 2,3-aminomutase
--|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|---  0    [G]    COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases
----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||--  0    [R]    COG1524 Uncharacterized proteins of the AP superfamily
----------|||---|----|--|--||-------||----|||----|-----|---||-||--  0    [C]    COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs
------||------------||----|--|----|-||----|||||-|||--|||--||------  0    [R]    COG1540 Uncharacterized proteins, homologs of lactam utilization protein B
-----------------|--|---|-|----------|----|--||-||||-------||--|--  0    [G]    COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
----|--------||--|||-|----|||-||||||||----|||||--|---------||-||--  0    [I    R]    COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
|-|||---|--------|||-------------|--------||||--------|--|--|-||-|  0    [S]    COG1598 Uncharacterized conserved protein
-------------||--|--------|---|-|||-||-----||---|--|---|---|------  0    [G]    COG1621 Beta-fructosidases (levanase/invertase)
-----------------||-|---|-|---------||----|--||-||||---|---||-||--  0    [G]    COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
|-||||||||--|---------------------|--------||-|-|----------||-|---  0    [R]    COG1661 Predicted DNA-binding protein with PD1-like DNA-binding motif
-||-----|--------||--|-------------------------------|-----|---|--  0    [R]    COG1669 Predicted nucleotidyltransferases
|||---|||||-|------------------------------------|---------||-|---  0    [S]    COG1679 Uncharacterized conserved protein
|-|-------------||--|---------|----|||--------|-||-----|---||-|---  0    [S]    COG1683 Uncharacterized conserved protein
|-|||||||-|||----|-|||----||||||||||||----|||||-|------|------||--  0    [K]    COG1695 Predicted transcriptional regulators
-------------||----||---|-----|||||||------------|---||-|-|-|-----  0    [M]    COG1696 Predicted membrane protein involved in D-alanine export
|||---|||||||---||------------|---|-----------|---|--------||----|  0    [R]    COG1708 Predicted nucleotidyltransferases
||||--|||||||----|------------------------|||||-||||-||-------||--  0    [S]    COG1720 Uncharacterized conserved protein
--|--------------|||-------------------------|-----------|--|-||--  0    [N]    COG1724 Predicted periplasmic or secreted lipoprotein
||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||--  0    [K]    COG1733 Predicted transcriptional regulators
-----------|---------|-----||------|-|-||-|---|------------|--|---  0    [R]    COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold
--|---------------|--------||-----|-||----|||-|--|-----|---||-||--  0    [S]    COG1742 Uncharacterized conserved protein
------||||--|----|------------------------------------------|-----  0    [L]    COG1743 Adenine-specific DNA methylase containing a Zn-ribbon
-||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||--  0    [O]    COG1765 Predicted redox protein, regulator of disulfide bond formation
|||---|||||-|------------------------------------|---------||-|---  0    [S]    COG1786 Uncharacterized conserved protein
|||||||||||||||||----------||-------||----------|||--||---|||-||--  0    [L]    COG1793 ATP-dependent DNA ligase
------|||----------------------|----|-----|||||----|---|--|||-||--  0    [M]    COG1794 Aspartate racemase
--|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||--  0    [S]    COG1801 Uncharacterized conserved protein
------------------||--||---------------------|--||||-||-------|---  0    [C]    COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB
||--|||||||||||--|---||---|----|-----------------|------------||--  0    [S]    COG1814 Uncharacterized membrane protein
-------------||----|----|--|-|||----------|||-|-||-----|---||-||--  0    [F]    COG1816 Adenosine deaminase
|||------|---|----|--|-----||||-----|------||||-||------------|---  0    [G    C]    COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
||||--||||-||---|--|--||------------------|||||----|-------||-|---  0    [G]    COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
---|||||--|||---||---|---------|||-|||----|||||--------|--|||-|---  0    [R]    COG1832 Predicted CoA-binding protein
--|---------|-----||-------||-|-----||-----------|----------|-|---  0    [E]    COG1834 N-Dimethylarginine dimethylaminohydrolase
--|-------------|-||-|----|||-|----|||----|||||-||------------||--  0    [K    T]    COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
-|----|||-|||--------|-----||-------------------------------|-----  0    [R]    COG1848 Predicted nucleic acid-binding protein, contains PIN domain
-||---|||---------||----------------|-----------------------|-|---  0    [G]    COG1850 Ribulose 1,5-bisphosphate carboxylase, large subunit
--|-------------|----|--------------------|||||-||-|---|||||--|---  0    [P]    COG1858 Cytochrome c peroxidase
--|-|||||||-|||-----||--------------------|||----|---------|------  0    [J]    COG1859 RNA:NAD 2'-phosphotransferase
--||--|||--------|-------|----|-----||----------||-----|---||--|--  0    [N    T]    COG1871 Chemotaxis protein; stimulates methylation of MCP proteins
|||----|||--|------|--||----|-------------|||||-|--|-------|--||||  0    [S]    COG1872 Uncharacterized conserved protein
------||---------|------------|--|--||-------|------|-------|--|--  0    [G]    COG1874 Beta-galactosidase
|---||----|--|||----------||||------------|||-|--------|------|---  0    [G]    COG1877 Trehalose-6-phosphatase
||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|---  0    [R]    COG1878 Predicted metal-dependent hydrolase
|-|||||||--|-|--|-----||--|||||---|-|-|---|||-|-|--|||||||-||-|--|  0    [R]    COG1881 Phospholipid-binding protein
---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||--  0    [H]    COG1893 Ketopantoate reductase
||--|----|------|-------------------------|||||--|||----|||||-|---  0    [E]    COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase]
--|-||----------|--|-------||--------------------------|||--|-|---  0    [R]    COG1926 Predicted phosphoribosyltransferases
------------------||-|----||||||--||||----|||-|--|-----|--|||-----  0    [S]    COG1937 Uncharacterized protein conserved in bacteria
|-------|----------|------|----|||||||----||||------|||||||||-||--  0    [R]    COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog
--||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||--  0    [L]    COG1943 Transposase and inactivated derivatives
||||-----|-----------------||-------------|||||--|||-------||-|---  0    [S]    COG1944 Uncharacterized conserved protein
---|||-------|---|------------||||||||----|||||-||-||||-------||--  0    [T]    COG1956 GAF domain-containing protein
------------------|||------||||--|||||----|||||-||||---|----|-----  0    [E]    COG1982 Arginine/lysine/ornithine decarboxylases
------||-----|------||----||||----|-||----|||||-|||--|||--||---|--  0    [E]    COG1984 Allophanate hydrolase subunit 2
||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||--  0    [N    O    U]    COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
||||||-||||||---||||-|-----||-|----|||----------|----|||||--|-||--  0    [R]    COG1994 Zn-dependent proteases
---------------------|--|-|||||---|||||||||||||--|||||||----|--|||  0    [S]    COG2001 Uncharacterized protein conserved in bacteria
---|--|||-|||-----||-------||-|----|||----|||--------------||-|---  0    [K]    COG2002 Regulators of stationary/sporulation gene expression
|-|-----||||------------------------------|||||--|||---|--|||-||--  0    [R]    COG2005 N-terminal domain of molybdenum-binding protein
|-||||-|||-||----||--|--------|||----------------|------------||--  0    [S]    COG2013 Uncharacterized conserved protein
|-||---------||------|----||||----||-------------|||||||------||--  0    [E]    COG2021 Homoserine acetyltransferase
-||---|-|---|-----|||------||----|--------|--||-|------|---||-----  0    [J    D]    COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system
-------------||---|--------||||-----|-----|----------------|--|---  0    [E]    COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent)
------||-----|------||----||||----|-||----|||-|-|||--|||--||---|--  0    [E]    COG2049 Allophanate hydrolase subunit 1
-|---------------|||||---||---------||-|--------||-----|---||-||--  0    [P]    COG2059 Chromate transport protein ChrA
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  0    [P]    COG2060 K+-transporting ATPase, A chain
|||||||||||||-------------||--|--------------|---|-|---|---||-||--  0    [N    U]    COG2064 Flp pilus assembly protein TadC
|--------||||--------|-----||-------||----|||----------|---||-||--  0    [R]    COG2068 Uncharacterized MobA-related protein
-------------||---|--|----||||------||-----------|-----|---||-||--  0    [P]    COG2072 Predicted flavoprotein involved in K+ transport
|---||----||||------------|||-------||----|||-|--|-----|---||-|---  0    [R]    COG2079 Uncharacterized protein involved in propionate catabolism
----------|||--------|--||-||-------||----|||----|-----|---||-||--  0    [C]    COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs
||||----||---------|------|----|--------------------|--|---||-|---  0    [R]    COG2085 Predicted dinucleotide-binding enzymes
------------|--|-----|-|-|-||||---|||------------|---------||-|-||  0    [L]    COG2094 3-methyladenine DNA glycosylase
------------------||-|--------||--|-||----|||||-|-||--------|-|---  0    [R]    COG2103 Predicted sugar phosphate isomerase
--|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|---  0    [R]    COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1
--|----------|||--||----|-||||-------------------|---------||-||--  0    [T]    COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)
|||-----||----------------------------------------------------|---  0    [S]    COG2122 Uncharacterized conserved protein
|||---|||||||---|-------------------------------------------|-----  0    [R]    COG2129 Predicted phosphoesterases, related to the Icc protein
---|---------||----|--------------|-|-----|||-|--|-----|------||--  0    [R]    COG2130 Putative NADP-dependent oxidoreductases
----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||--  0    [G]    COG2133 Glucose/sorbosone dehydrogenases
-----------------|--||--|-||||||||||||----|||||-||||-|||---|------  0    [R]    COG2137 Uncharacterized protein conserved in bacteria
--|---|||---------|-----------------|---------|--------|---||-|---  0    [G    R]    COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes
--|---|||----||-----------|---||-|||||----|||-|---||----||-|------  0    [H]    COG2145 Hydroxyethylthiazole kinase, sugar kinase family
--||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||--  0    [P    R]    COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
--|-------------------||------|-----||----------------------|-|-|-  0    [S]    COG2155 Uncharacterized conserved protein
---|||------------||-|-----||-|---||------|||||--|-----|---||-||--  0    [P]    COG2156 K+-transporting ATPase, c chain
---|--||-|-||-----|-------|||-|---||-----------------------||-||--  0    [R]    COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold
-----------------|------------|-----||----|||||-------------|-----  0    [G]    COG2160 L-arabinose isomerase
---|-------------|||-------||----||-------|||-|-|----------|-----|  0    [D]    COG2161 Antitoxin of toxin-antitoxin stability system
---------------------------||-----|-||----|||-|--|------------||--  0    [Q]    COG2162 Arylamine N-acetyltransferase
----------------||||||||------||||||||----|||||-|||||--|--|---||--  0    [N    U]    COG2165 Type II secretory pathway, pseudopilin PulG
------------------||-------||-------------|||-|---------------||--  0    [M]    COG2173 D-alanyl-D-alanine dipeptidase
-------------||------------|||------------||||--||-----|------|---  0    [Q]    COG2175 Probable taurine catabolism dioxygenase
----|-||--|||----|---|---------|||||||----|||||-|----------|------  0    [G]    COG2182 Maltose-binding periplasmic proteins/domains
---------------------------||----|--------|||-|--||-|||-||-||-|---  0    [D]    COG2184 Protein involved in cell division
----------------|-||-------||--------------------|------------||--  0    [S]    COG2187 Uncharacterized protein conserved in bacteria
-----|--|-----------|-----|------|-|--||------|---|||-|-||-|--|---  0    [L]    COG2189 Adenine specific DNA methylase Mod
-|----||-|--------|--|---------------------------|-----|----|-|---  0    [O]    COG2192 Predicted carbamoyl transferase, NodU family
--|-----------------||---|----||||||||----|||||-|-||------|-|--|--  0    [E]    COG2195 Di- and tripeptidases
-------------||---||----------------------|||||-||||----------|---  0    [T]    COG2198 FOG: HPt domain
--||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||--  0    [N    T]    COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
------------------||-|-----||-|---||------|||||-||-----|--|||-||--  0    [T]    COG2205 Osmosensitive K+ channel histidine kinase
----------------||-|-|--||----|------|----------||-----|---|--|---  0    [T]    COG2206 HD-GYP domain
-----------------||||-|||--||-|---||||----------||----------|-|---  0    [T    K]    COG2208 Serine phosphatase RsbU, regulator of sigma subunit
---|||------------||-|-----||-|---||------|||||--|-----|--|||-||--  0    [P]    COG2216 High-affinity K+ transport system, ATPase chain B
---|||-----|-------------|-||--|||||----|-----|-||----------|-|---  0    [E]    COG2235 Arginine deiminase
---||||||||||-----||------||||||-||||-----|---|--|-----|------||--  0    [S]    COG2246 Predicted membrane protein
--|-----------|-----|---------|----||||---|||||-||||-||||||-|-||--  0    [R]    COG2249 Putative NADPH-quinone reductase (modulator of drug activity B)
------------------||------|----|----||----|||-|--|------------|---  0    [S]    COG2268 Uncharacterized protein conserved in bacteria
----------------|-------|-----------------|||||||-|||------||-||--  0    [J]    COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II)
-------------||--|---------||-|-----||---------------------||-||--  0    [G]    COG2273 Beta-glucanase/Beta-glucan synthetase
------------------||----------||-|--||||||-||||-||--||||----|-||--  0    [V]    COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
--|-----|--||-----||||---|||||------||----|--||-||------------|---  0    [R]    COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain
------------------|--|-----|||-------------------|-----|---||-||--  0    [S]    COG2307 Uncharacterized protein conserved in bacteria
-----------|------|--|-----|||-------------------|-----|---||-||--  0    [S]    COG2308 Uncharacterized conserved protein
---|-----------------|-----||-------||----------------------|--|--  0    [R]    COG2312 Erythromycin esterase homolog
--------------|--|---|------------||------|||--------------||-|---  0    [Q]    COG2313 Uncharacterized enzyme involved in pigment biosynthesis
--------------------||----|----|||-||-----|||||--|-----|---|--||--  0    [S]    COG2315 Uncharacterized protein conserved in bacteria
---|--||--|||-------||-------------|||-------|--|-------------|--|  0    [E]    COG2317 Zn-dependent carboxypeptidase
-------------------|||--------||-|--||----|||-|-------------|-----  0    [S]    COG2323 Predicted membrane protein
--|----------||---||-|-----||------------------------------||-||--  0    [M]    COG2335 Secreted and surface protein containing fasciclin-like repeats
-------------------|-|---------------|----|||--------|||---|------  0    [T]    COG2336 Growth regulator
------------------||-|-----||--------------------------|----|-|---  0    [S]    COG2343 Uncharacterized protein conserved in bacteria
----||---------------|----|||-----||------|||||-||--|||||||||-||--  0    [S]    COG2353 Uncharacterized conserved protein
-||---------------|--|-------------------------------|-----|---|--  0    [S]    COG2361 Uncharacterized conserved protein
------||----|--------|-------------||------------------|------|---  0    [E]    COG2362 D-aminopeptidase
-------------||------|-----||--|---|---------|---|-----|---|---|--  0    [T]    COG2365 Protein tyrosine/serine phosphatase
------------------||||-----||||||||||----------------------||-----  0    [V]    COG2367 Beta-lactamase class A
----------------|-||-|---------------------------|-----|---|--|---  0    [O]    COG2370 Hydrogenase/urease accessory protein
---------------------|----|--------|||----|||||--------|----|-|---  0    [R]    COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC
-----------------|-|||--------------------|||||--|-||--|---||-||||  0    [R]    COG2373 Large extracellular alpha-helical protein
---------------------|----|||-------------|||-|-||-----|---||-----  0    [P]    COG2375 Siderophore-interacting protein
------||---||-|--|-|---------------|-|----------------------|--|--  0    [C]    COG2421 Predicted acetamidase/formamidase
----||----|||----|--|---------------------|||-|-------------|-|---  0    [C]    COG2440 Ferredoxin-like protein
---------------------|----||||||||-|||-----------|---------|------  0    [T    Q]    COG2508 Regulator of polyketide synthase expression
----||----|||------|------|||------|||----|||-|-||--||||----|-||--  0    [G]    COG2513 PEP phosphonomutase and related enzymes
------||------|--|-|----------------------|||||-|------|--|---||--  0    [E]    COG2515 1-aminocyclopropane-1-carboxylate deaminase
------------------||--------------|-|------------|-----|--||--|--|  0    [V]    COG2602 Beta-lactamase class D
---------------------|----||||------------||||||||||||||------||--  0    [C]    COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component
|||------|--------|||---------|-----------------------------|-|---  0    [C]    COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains
---|--------------------------|-----||----|||||-||----------|-|---  0    [S]    COG2718 Uncharacterized conserved protein
---|--------------------------|-----||----|||||-||----------|-|---  0    [S]    COG2719 Uncharacterized conserved protein
----||||--||--------------|---||||||||----|||||-|----------||--|--  0    [G]    COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase
--------------------------|||-|-----------|||-|-----|---------|---  0    [S]    COG2733 Predicted membrane protein
-------------------|-|--------|----||---------------------|-|-|---  0    [V]    COG2746 Aminoglycoside N3'-acetyltransferase
----||-------||--|--|---------||||||--|---------|----||-----|-|---  0    [F]    COG2759 Formyltetrahydrofolate synthetase
-------------------|------|||-||--||-|----|||-|--|-----|----|-||--  0    [S]    COG2764 Uncharacterized protein conserved in bacteria
---|--------------------------|-----||----|||||-||----------|-|---  0    [T]    COG2766 Putative Ser protein kinase
--|-----|-------|-||-|--------------|-----------||-----|---||-|---  0    [T]    COG2770 FOG: HAMP domain
----------------||||||||------||||||||----|||||-||||||||--|---||--  0    [N    U]    COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB
-------------|-------|--------------||-----------|--|--|------||--  0    [K]    COG2808 Transcriptional regulator
--------------------------|||--|--||||----|||||--||||--||||||-|---  0    [G]    COG2814 Arabinose efflux permease
---------------------|--------|--|--|------||-|--|---|----||---|--  0    [R]    COG2819 Predicted hydrolase of the alpha/beta superfamily
---------------------|--------|-----------|||||-||||-|||----|---||  0    [R]    COG2823 Predicted periplasmic or secreted lipoprotein
--------------------------|||--|-|---|-|--|||--------|||---||--|--  0    [L]    COG2826 Transposase and inactivated derivatives, IS30 family
------------------------------------|-----|||---||--||||---||-|---  0    [S]    COG2828 Uncharacterized protein conserved in bacteria
-------------------|-|----|||-----|||-----|||||-||-|-|||------|---  0    [P]    COG2837 Predicted iron-dependent peroxidase
--|------------------|-----||---||-||----------------||-----|-||--  0    [M]    COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
------------------------------|---|-------|||||---|--|||----|-----  0    [D]    COG2846 Regulator of cell morphogenesis and NO signaling
-------------------|-|-------------|------|-------|--||-----|--|--  0    [S]    COG2852 Uncharacterized protein conserved in bacteria
-------------------------|-----------|----|||-|--|||------|||-||--  0    [S]    COG2861 Uncharacterized protein conserved in bacteria
--|-------------|----|--------------------|||-||||||---|||||---|--  0    [S]    COG2862 Predicted membrane protein
---------------------|-----------------------|--||-|-||||||-|-----  0    [C]    COG2863 Cytochrome c553
--|-----|-------|-------------------------|||||-||||---|--|-|-----  0    [C]    COG2864 Cytochrome b subunit of formate dehydrogenase
-|--------------|---|---------------------||||||-|||-||||||---||--  0    [M]    COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase
---------------------------||-------------------|----||----|--||--  0    [R]    COG2907 Predicted NAD/FAD-binding protein
-----------------|------------------------|||||-|||||||||||||-||--  0    [S]    COG2908 Uncharacterized protein conserved in bacteria
-------------------------------|-|-||-----------||-----|--|||-|---  0    [R]    COG2910 Putative NADH-flavin reductase
---|---------------||-||-------------|-----------|--||||---||-|---  0    [S]    COG2928 Uncharacterized conserved protein
----------------|-||-------------------------|--||--||||---||-||--  0    [Q]    COG2931 RTX toxins and related Ca2+-binding proteins
------------------|--------||--|--||----------------|-------|-||--  0    [R]    COG2936 Predicted acyl esterases
--|----------|||------||----------------------------|--|------|---  0    [R]    COG2940 Proteins containing SET domain
-------------------|----------------------|||-|-|---||||---||----|  0    [K]    COG2944 Predicted transcriptional regulator
------------------||--------------------------------|||----||-|---  0    [S]    COG2954 Uncharacterized protein conserved in bacteria
--------------------|-----------|---------|||||-||||---|--|-|-----  0    [S]    COG2964 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-|-||-||---|---|---  0    [S]    COG2990 Uncharacterized protein conserved in bacteria
------------------|-----------------------------|----|-|----|-----  0    [O]    COG2994 ACP:hemolysin acyltransferase (hemolysin-activating protein)
-------------||---||-------||-------------------||-----|---||-||--  0    [I]    COG3000 Sterol desaturase
------------------------------------------|||||-||||------|||-----  0    [C]    COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit
------------------||--------------|-||-------|--||--|--|------||--  0    [S]    COG3011 Uncharacterized protein conserved in bacteria
----------|-----|-------------------------------||-|------|-|-----  0    [R]    COG3019 Predicted metal-binding protein
--|---------------------------------------|||||-||||---|------||--  0    [S]    COG3025 Uncharacterized conserved protein
--||||---------------------||-------------|-----|----|||---||-|---  0    [L]    COG3039 Transposase and inactivated derivatives, IS5 family
--------------------------|---------------|||-|-||--------||--||--  0    [M]    COG3040 Bacterial lipocalin
-------------------|-------------|--------|||-|-|-|-|---||-|------  0    [S]    COG3041 Uncharacterized protein conserved in bacteria
--------|---------------------------------|||||-|----|||------|---  0    [R]    COG3042 Putative hemolysin
------------------------------------------|||||-||||------|||-----  0    [C]    COG3043 Nitrate reductase cytochrome c-type subunit
|--|--------------|-----------------------------|----------|---|--  0    [R]    COG3046 Uncharacterized protein related to deoxyribodipyrimidine photolyase
----------------|-------------------------|||||--|||--------|-----  0    [O]    COG3058 Uncharacterized protein involved in formate dehydrogenase formation
------------------------------------------|||||-||||------|||-----  0    [P]    COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase
------------------------------|--|||------|||||-||||-|-|----|-||-|  0    [K]    COG3070 Regulator of competence-specific genes
--------------------|-----------||--------|||||-|-|-|------||----|  0    [L]    COG3077 DNA-damage-inducible protein J
--------------------|-----|----------|----|--||-||||-------||--|--  0    [G]    COG3090 TRAP-type C4-dicarboxylate transport system, small permease component
-------------------||-----|---------------|||---|||-|-------|-||--  0    [R]    COG3093 Plasmid maintenance system antidote protein
------------------|--|--------------------|||||--|--|--|---||-|--|  0    [N    U]    COG3121 P pilus assembly protein, chaperone PapD
------------------------------------------|||----|--|---------||--  0    [S]    COG3128 Uncharacterized iron-regulated protein
------------------------------------------|||||-||------------|---  0    [S]    COG3132 Uncharacterized protein conserved in bacteria
------------------------------------------|||||-||------------|---  0    [R]    COG3136 Uncharacterized membrane protein required for alginate biosynthesis
--------------------|----------|||-|------|||||-|--||------||-||--  0    [P]    COG3142 Uncharacterized protein involved in copper resistance
-------------------------------|--||------|||||-||----------|-||--  0    [S]    COG3152 Predicted membrane protein
------------------------------------------|--|--||--|--|------||--  0    [U]    COG3156 Type II secretory pathway, component PulK
------------------------------------------|||||-||-----|---|--|---  0    [S]    COG3157 Hemolysin-coregulated protein (uncharacterized)
------------------||----------------------|||||-||--||||------|---  0    [N    U]    COG3166 Tfp pilus assembly protein PilN
--||-----------------|-----||--|---|||-----------|-----|---||-||-|  0    [R]    COG3173 Predicted aminoglycoside phosphotransferase
|-||-----|--|---|--------------------------------|-----|----|-|---  0    [S]    COG3174 Predicted membrane protein
--||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--|  0    [S]    COG3177 Uncharacterized conserved protein
---------------------|------------------------|--||---------|-----  0    [R]    COG3179 Predicted chitinase
-------------------||-----|-------|-||----|||-|-||---------||-|---  0    [R]    COG3180 Putative ammonia monooxygenase
--------------------|-----|---------||--------|-||-|---|---||-----  0    [S]    COG3181 Uncharacterized protein conserved in bacteria
--------------------------|-------|--|----------||---|||---|---|--  0    [S]    COG3182 Uncharacterized iron-regulated membrane protein
--|------------------|------------------------|-||------------|---  0    [V]    COG3183 Predicted restriction endonuclease
------------------||------|---------------------||-----|---||-||--  0    [E    R]    COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins
-----------------------|------------------------||-----|------||--  0    [E]    COG3186 Phenylalanine-4-hydroxylase
------------------|-----------------------|||||--|--|--|---|--|--|  0    [N    U]    COG3188 P pilus assembly protein, porin PapC
------------------------------------------------||---||||||-|-||--  0    [P]    COG3197 Uncharacterized protein, possibly involved in nitrogen fixation
-------------------|-------||||-----||-------|---|-----|---|--|---  0    [Q]    COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis
--|---------------------------|----||-----|||||--|-----|------|---  0    [M]    COG3209 Rhs family protein
-------------------|-----------------|----------||--------|||-||--  0    [R]    COG3211 Predicted phosphatase
--|-----------------|-----------|-||||----------||---||-------||--  0    [S]    COG3212 Predicted membrane protein
---------------------|-----||-------------|||-|--|---------||-||--  0    [S]    COG3214 Uncharacterized protein conserved in bacteria
---|---------------|----------------------|||||-||---------||-||--  0    [R]    COG3217 Uncharacterized Fe-S protein
------------------------------|------------------|||-|||----|--|--  0    [S]    COG3220 Uncharacterized protein conserved in bacteria
---|------|--------||-----|||--|--|--|----||||--||---------||-||--  0    [P]    COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component
---------------------|---------------------------|---||----|------  0    [P]    COG3230 Heme oxygenase
---------------------|-----||--|-----------------|----------|-|---  0    [J]    COG3231 Aminoglycoside phosphotransferase
-------------------|------|----||||||-----|||-|--|---------||-||--  0    [S]    COG3237 Uncharacterized protein conserved in bacteria
-------------------|-|----|---||--||------|||-|--|-|-------|--|---  0    [S]    COG3238 Uncharacterized protein conserved in bacteria
------------------||-------||-------|------------|-----|----|-||--  0    [I]    COG3239 Fatty acid desaturase
--------|---------|--------|||------------------||-----|---||-||||  0    [I]    COG3243 Poly(3-hydroxyalkanoate) synthetase
--------|-----------||-----|---------------------|-----|---||-|---  0    [S]    COG3246 Uncharacterized conserved protein
------------------------------------------------||--|---------|---  0    [S]    COG3249 Uncharacterized protein conserved in bacteria
-----------|-----|-------------|||---|----||||------|------||-----  0    [G]    COG3250 Beta-galactosidase/beta-glucuronidase
---------------------------||-------|------|--|--|-----|---|------  0    [S]    COG3251 Uncharacterized protein conserved in bacteria
----||--|-|||---|--------------------|-----------|------------||--  0    [I]    COG3255 Putative sterol carrier protein
--------------------|----------------|----|||-|-||---------|--|---  0    [P]    COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain
-------------||----|-|----|---------------|||||-||-|-|||---||-|---  0    [G]    COG3265 Gluconate kinase
--------------------|-------------|-|-----|||||-|-----------|-----  0    [T]    COG3275 Putative regulator of cell autolysis
-||-||---|-|----|-------------------------|||-|--|||------|-|-----  0    [J]    COG3276 Selenocysteine-specific translation elongation factor
-----------|-------|-|----|||-----------------|--|-----|----|-----  0    [G]    COG3280 Maltooligosyl trehalose synthase
---------------------------||-------||-----------|---------||-|---  0    [L]    COG3285 Predicted eukaryotic-type DNA primase
-|-------|---------|----------------------------||----------|-|---  0    [S]    COG3287 Uncharacterized conserved protein
------------------|-----------------|---------|--|-----|---||-||--  0    [T]    COG3300 MHYT domain (predicted integral membrane sensor domain)
----------------|-------------------------|||||---||----------|---  0    [R]    COG3302 DMSO reductase anchor subunit
--------------------|---------|---|-||----|||-|-|-----------|-----  0    [S]    COG3314 Uncharacterized protein conserved in bacteria
--|----------------||------|||------|-----------||-|--------|-|---  0    [Q]    COG3315 O-Methyltransferase involved in polyketide biosynthesis
-------------||----|-------|||----|--------------|---------|------  0    [Q]    COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes
-------------------|------|||||-----|--------|---------|---||-|---  0    [Q]    COG3321 Polyketide synthase modules and related proteins
--|-----|------------------------------------|--||----------|--|--  0    [T]    COG3322 Predicted periplasmic ligand-binding sensor domain
--|----------------------------|||-|||--------|--|---||-|--|------  0    [S]    COG3326 Predicted membrane protein
-----------|---------------||--------|----|-----------------|-----  0    [K]    COG3327 Phenylacetic acid-responsive transcriptional repressor
--|-||-----|------|--------||-||-----||----||||--------|----|-|---  0    [L]    COG3328 Transposase and inactivated derivatives
--------------------|-----|----------|--------|-||-|---|---||-----  0    [S]    COG3333 Uncharacterized protein conserved in bacteria
--|--|--|--|------||-|----|------|---|-----||-|-------||----|-|---  0    [L]    COG3335 Transposase and inactivated derivatives
---------------------|----||||------||----------------------|-|---  0    [S]    COG3336 Predicted membrane protein
-------------------|---------------|-|----------|--|----||--|-|---  0    [P]    COG3338 Carbonic anhydrase
--|----------|----|||------||-|---|--|----|--||-||----------|-----  0    [L]    COG3344 Retron-type reverse transcriptase
----|-------------|-----------------||-------|-------------||-|---  0    [S]    COG3347 Uncharacterized conserved protein
---|-----------------------||--------------------|-----|----|-----  0    [S]    COG3360 Uncharacterized conserved protein
|--|||---|-------|-|----------------------------------------|-----  0    [S]    COG3367 Uncharacterized conserved protein
|-|-||------|------------------------------------------|------|---  0    [S]    COG3369 Uncharacterized conserved protein
---------||||-----------------|||---||--------|--|-----|------|---  0    [S]    COG3382 Uncharacterized conserved protein
|---||-----|----------------------|||----------------------||-|---  0    [R]    COG3383 Uncharacterized anaerobic dehydrogenase
--||-|-----|------||-|---------------|----|------------|----|-----  0    [L]    COG3385 FOG: Transposase and inactivated derivatives
-||-||-----|-||----|------|||-|------------------------|---|--||--  0    [G]    COG3387 Glucoamylase and related glycosyl hydrolases
--|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|---  0    [S]    COG3391 Uncharacterized conserved protein
-----------|---------|---------------|----|------------|----|-----  0    [S]    COG3396 Uncharacterized conserved protein
----------------|--------------------|----|||-|------------|------  0    [G]    COG3405 Endoglucanase Y
--|-||||---|-|-----|-|---------------|----------------------|-|---  0    [G]    COG3408 Glycogen debranching enzyme
--------------------||---------|-|||-|----|||-----------------|---  0    [S]    COG3412 Uncharacterized protein conserved in bacteria
---|----|--|-------|-|---------------|----------------------|-|---  0    [L]    COG3415 Transposase and inactivated derivatives
-----------------------------------------------|-|--|--|---|------  0    [S]    COG3416 Uncharacterized protein conserved in bacteria
-------------------------------||||-|-----|||-|------------|--|---  0    [R]    COG3443 Predicted periplasmic or secreted protein
------------------||----------------------|||-|--|----------|-|---  0    [T]    COG3447 Predicted integral membrane sensor domain
------------------|------------------------------|-----|---||-|---  0    [T]    COG3448 CBS-domain-containing membrane protein
------------------------------|----|||----|||-|--------|------||--  0    [L]    COG3449 DNA gyrase inhibitor
-----------------|-|--------------------------|--|---------||-|---  0    [R]    COG3450 Predicted enzyme of the cupin superfamily
------------------||----------------------------|-----------|-|---  0    [T]    COG3452 Predicted periplasmic ligand-binding sensor domain
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3455 Uncharacterized protein conserved in bacteria
-------------------------------------------|||--||---------|--|---  0    [T]    COG3456 Uncharacterized conserved protein, contains FHA domain
-----------------|----------------|--|----|---|---------------|---  0    [E]    COG3457 Predicted amino acid racemase
-----------------|---------------|--||---------------------|--|---  0    [Q]    COG3458 Acetyl esterase (deacetylase)
---------------------|---------------|----|------------|----|-----  0    [Q]    COG3460 Uncharacterized enzyme of phenylacetate metabolism
----||-----------|--------------------------------------------|---  0    [S]    COG3461 Uncharacterized conserved protein
--|--|-------------||-----|||----||--|-----------------|---||-|---  0    [L]    COG3464 Transposase and inactivated derivatives
------||---||------------------------------------------|----|-|---  0    [Q]    COG3473 Maleate cis-trans isomerase
--|-----|-----|---||----------||----|----------------------||-----  0    [T]    COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
-|-------|----------|---------||||||||----------------------|-----  0    [R]    COG3481 Predicted HD-superfamily hydrolase
|-|------------------------||------------------------------||-|---  0    [S]    COG3482 Uncharacterized conserved protein
---------------------|---------------------------|-----|------||--  0    [E]    COG3483 Tryptophan 2,3-dioxygenase (vermilion)
------------------|------------------------------|-----|------|---  0    [O]    COG3484 Predicted proteasome-type protease
---|----------|----|-----------------|-------|---|-----|----|-|---  0    [Q]    COG3486 Lysine/ornithine N-monooxygenase
------------------------------------------------||---------||-|---  0    [P]    COG3487 Uncharacterized iron-regulated protein
------------------------------------------------||---------||-|---  0    [C]    COG3488 Predicted thiol oxidoreductase
------------------------------------------------||---------||-|---  0    [R]    COG3489 Predicted periplasmic lipoprotein
------------------------------------------------||---------||-|---  0    [S]    COG3490 Uncharacterized protein conserved in bacteria
--------------|------------------------------|---|-----|--|---||--  0    [R]    COG3491 Isopenicillin N synthase and related dioxygenases
------------------------------------------------||---------||-||--  0    [S]    COG3492 Uncharacterized protein conserved in bacteria
------------------------------------------------||------------|---  0    [S]    COG3495 Uncharacterized protein conserved in bacteria
---------------------------||-------------------|----------|--||--  0    [S]    COG3496 Uncharacterized conserved protein
-------------------|-----------------------||||--|--|--|---|--|---  0    [R]    COG3497 Phage tail sheath protein FI
-------------------------------------------||-|--|--|--|---|------  0    [R]    COG3499 Phage protein U
-------------------|----------------------|||-|--|--|--|---|--|---  0    [R]    COG3500 Phage protein D
-------------------|-----------------------||||-||-----|---|--|---  0    [S]    COG3501 Uncharacterized protein conserved in bacteria
-------------------|----------|---------------|-----|--|||-||-|-||  0    [U]    COG3505 Type IV secretory pathway, VirD4 components
-------------|-----|----------------------------|-----------|-|---  0    [S]    COG3506 Uncharacterized conserved protein
------------------------------||----||----|-----------------|--|--  0    [G]    COG3507 Beta-xylosidase
-----------|------------------------------------||-----|----|-||--  0    [Q]    COG3508 Homogentisate 1,2-dioxygenase
--------------------------||||-------------------|-----|---||-||--  0    [Q]    COG3509 Poly(3-hydroxybutyrate) depolymerase
------------------|--------|||------------------------------|-|---  0    [V]    COG3510 Cephalosporin hydroxylase
-----------|---------------||--------------------|-----|------||--  0    [M]    COG3511 Phospholipase C
---------------------------------------------||-----|||----||-|---  0    [S]    COG3514 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3515 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3516 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3517 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3518 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3519 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3520 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|------|---  0    [S]    COG3521 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3522 Uncharacterized protein conserved in bacteria
-------------------------------------------||||-||-----|---|--|---  0    [S]    COG3523 Uncharacterized protein conserved in bacteria
---------------------------------------------------|-||---|-|-----  0    [M]    COG3524 Capsule polysaccharide export protein
-------------------------------|-|--------------|---|------||--|--  0    [G]    COG3525 N-acetyl-beta-hexosaminidase
---------------------------------------------|--||-----|------|---  0    [O]    COG3531 Predicted protein-disulfide isomerase
-----------------|-------------------|-----||-|------------||-||--  0    [S]    COG3533 Uncharacterized protein conserved in bacteria
-----------------|------------|-----||---------------------||-||--  0    [G]    COG3534 Alpha-L-arabinofuranosidase
------|----|-----------------------|-|---------------------|--|---  0    [S]    COG3535 Uncharacterized conserved protein
-------------------|------|---------|------------|----------|-||--  0    [P]    COG3540 Phosphodiesterase/alkaline phosphatase D
-|-----------------|----------|-----|------------|-----|------|---  0    [R]    COG3541 Predicted nucleotidyltransferase
-------------|----|--------------||--------------------|---||-||--  0    [S]    COG3542 Uncharacterized conserved protein
------------------||-|----|---------------------------------|-|---  0    [S]    COG3544 Uncharacterized protein conserved in bacteria
--|--------|-------||-----||||--||---|-------|---|---||----||-||--  0    [L]    COG3547 Transposase and inactivated derivatives
|--------------------|---------|------------------------------||--  0    [S]    COG3548 Predicted integral membrane protein
-------------------|----------------------------|-|-|-------|-|---  0    [R]    COG3549 Plasmid maintenance system killer protein
--------------------|-----|---------------|||---|-|--|-|---||-||--  0    [R]    COG3550 Uncharacterized protein related to capsule biosynthesis enzymes
-------------------------------------|-----------|------------|---  0    [S]    COG3551 Uncharacterized protein conserved in bacteria
|-----------|--------------||--------------------------|----|-|---  0    [R]    COG3552 Protein containing von Willebrand factor type A (vWA) domain
---------------------------||--------------------|----------|-|---  0    [S]    COG3554 Uncharacterized protein conserved in bacteria
------------------|------------------------------|-----|------|---  0    [S]    COG3556 Predicted membrane protein
------------------|------------------------------|---------|--|---  0    [S]    COG3558 Uncharacterized protein conserved in bacteria
---------------------------------------------------|-||---|-|-----  0    [M]    COG3562 Capsule polysaccharide export protein
---------------------------------------------------|-||---|-|-----  0    [M]    COG3563 Capsule polysaccharide export protein
------------------|------------------------------|---------|--|---  0    [R]    COG3565 Predicted dioxygenase of extradiol dioxygenase family
-----------------------------------|--------------|-|---------|---  0    [S]    COG3566 Uncharacterized protein conserved in bacteria
-----------------------------------|--------------|-|---------|---  0    [S]    COG3567 Uncharacterized protein conserved in bacteria
-------------||------|---------------------------|---------||-|---  0    [L]    COG3569 Topoisomerase IB
---------------------|---------------------------|---------||-|---  0    [V]    COG3570 Streptomycin 6-kinase
---------------------------||--------------------|----------|-|---  0    [R]    COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold
-------------------|-|---------|-|-----------|--|----------|--||--  0    [S]    COG3575 Uncharacterized protein conserved in bacteria
|||----------------|||-----|||--|----------------|---------||-||--  0    [R]    COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
--|----------------|-----------------------------|||---|------|---  0    [H]    COG3585 Molybdopterin-binding protein
---------------|--|-|---------|---|-----------------|------||-|---  0    [G]    COG3588 Fructose-1,6-bisphosphate aldolase
---------------------------------||-|-----|||||-------------|-|---  0    [E]    COG3591 V8-like Glu-specific endopeptidase
--|----------------------------|---|------|||-----------------|---  0    [S]    COG3592 Uncharacterized conserved protein
-||---------------|-|---------------------|||||-||-|-------|--|---  0    [L]    COG3593 Predicted ATP-dependent endonuclease of the OLD family
--|---------------------------|---|||------------|--|---------|---  0    [G]    COG3594 Fucose 4-O-acetylase and related acetyltransferases
----------------|---------------|-------------------|---------|---  0    [L]    COG3598 RecA-family ATPase
------------------------------------------------||----------|-||--  0    [S]    COG3602 Uncharacterized protein conserved in bacteria
--|-----|------------|-------------------------------------||-|---  0    [S]    COG3603 Uncharacterized conserved protein
----------------|-------|-----------------|||-|-||-----|----|-|---  0    [K    T]    COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
--------------------------|----|--||-|---------------------||-|---  0    [R]    COG3607 Predicted lactoylglutathione lyase
-||||||||-|||------|-------||--------------||||-----|--|---||-||--  0    [K]    COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
--|-----------|----------|-----|------|----------|-----|---|--||--  0    [F]    COG3613 Nucleoside 2-deoxyribosyltransferase
------------------|--|--------------------------||------------|---  0    [T]    COG3614 Predicted periplasmic ligand-binding sensor domain
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3624 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3625 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3626 Uncharacterized enzyme of phosphonate metabolism
-------------------|----------------------||||---|---------||-|---  0    [P]    COG3627 Uncharacterized enzyme of phosphonate metabolism
-------------------|-------------------------||--|--|--|------|---  0    [R]    COG3628 Phage baseplate assembly protein W
-----------------|--|------||---|--------------------------||-|---  0    [T]    COG3629 DNA-binding transcriptional activator of the SARP family
--||-----------------|-----||-------|------------|---------|--||--  0    [R]    COG3631 Ketosteroid isomerase-related protein
---------------------------------------------|----|-|--|----|--|--  0    [K]    COG3636 Predicted transcriptional regulator
---|---------------||-----|----|--|--|-|--||||---|---------||-||--  0    [P]    COG3638 ABC-type phosphate/phosphonate transport system, ATPase component
---|------|--------||-----|----|--|--|-|||||||---|---------||-||--  0    [P]    COG3639 ABC-type phosphate/phosphonate transport system, permease component
---------------------|---------------------------|----------|-||--  0    [S]    COG3652 Predicted outer membrane protein
-------------------|-------------------------|----|-|--|----|--|--  0    [S]    COG3657 Uncharacterized protein conserved in bacteria
----------------------------------------------------|-------|--|||  0    [M]    COG3660 Predicted nucleoside-diphosphate-sugar epimerase
----------------------------------||-|-----------|----------|--|--  0    [G]    COG3664 Beta-xylosidase
--------------|------|--------------|----------------------||--|--  0    [S]    COG3665 Uncharacterized conserved protein
--|----------------||---------|-|||--|-----------|---------||--|--  0    [L]    COG3666 Transposase and inactivated derivatives
------------------||----------------------|||||-||----||----|-----  0    [U    N    T    P]    COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
--------------------------------||||------|||-|---------------|---  0    [G]    COG3684 Tagatose-1,6-bisphosphate aldolase
-------------------|----------------------|||-|--|---------||-|---  0    [S]    COG3685 Uncharacterized protein conserved in bacteria
-----------------|-|----------|------|---------------------|---|--  0    [G]    COG3693 Beta-1,4-xylanase
----------------|-||----------------------|||-|--|-----|||--|--|--  0    [P]    COG3696 Putative silver efflux pump
----------------------------------------------------|--|---|--||--  0    [U]    COG3701 Type IV secretory pathway, TrbF components
--------------------|------||||----|-------------|-----|---||-||--  0    [T]    COG3707 Response regulator with putative antiterminator output domain
--------------------|---------|---||||-----------|-|-------||-|---  0    [S]    COG3708 Uncharacterized protein conserved in bacteria
---------------------------||--------|----|||||-|-----------|-|---  0    [K]    COG3710 DNA-binding winged-HTH domains
------------------------------------------|------|-----|---||--|--  0    [P    T]    COG3712 Fe2+-dicitrate sensor, membrane component
--------------------|---------------------|||||-|--|---|---||-||--  0    [M]    COG3713 Outer membrane protein V
------------------------------------||----|||||------------||--|--  0    [G]    COG3717 5-keto 4-deoxyuronate isomerase
-------------------------------------------|||---|-----|----|-|---  0    [P]    COG3720 Putative heme degradation protein
-------------------------------------------|||--|--|-------|------  0    [P]    COG3721 Putative heme iron utilization protein
------------------------------------------|||-|-------||----|--|--  0    [L]    COG3727 DNA G:T-mismatch repair endonuclease
-------------------------------||-|||------|||---|------------|---  0    [L]    COG3728 Phage terminase, small subunit
-----------------------------------|-|----|||-|----|----------|---  0    [G]    COG3730 Phosphotransferase system sorbitol-specific component IIC
-----------------------------------|-|----|||-|----|----------|---  0    [G]    COG3731 Phosphotransferase system sorbitol-specific component IIA
-----------------------------------|-|----||--|----|----------|---  0    [G]    COG3732 Phosphotransferase system sorbitol-specific component IIBC
-----------|--|----|-|--------------------|-------------------|---  0    [Q]    COG3733 Cu2+-containing amine oxidase
-------------------------------|---|||-------------|-------|---|--  0    [S]    COG3739 Uncharacterized integral membrane protein
---------------------------||--|---|-------||-|--------|---|---|--  0    [R]    COG3740 Phage head maturation protease
---------------------------||-------------------------------|-||--  0    [S]    COG3742 Uncharacterized protein conserved in bacteria
------------------||-------||------------------------|-----||-----  0    [S]    COG3744 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||-||--  0    [U]    COG3745 Flp pilus assembly protein CpaB
--------------|------------||--|---|-----------------------|--||--  0    [S]    COG3752 Predicted membrane protein
-------------------------------||--------------------------|--||--  0    [M]    COG3754 Lipopolysaccharide biosynthesis protein
-------------------|-|--------------------|||-|--|---------||-||--  0    [S]    COG3755 Uncharacterized protein conserved in bacteria
------------------------------------------|---------|---------|---  0    [S]    COG3756 Uncharacterized protein conserved in bacteria
--------------------------|----|-|||--------------|--|||---|--|---  0    [S]    COG3759 Predicted membrane protein
------------------------------------||----|||-|--------|---|---|--  0    [S]    COG3766 Predicted membrane protein
-------------------|----------|-----------|||||-----|--|------||-|  0    [R]    COG3772 Phage-related lysozyme (muraminidase)
-------------||-----|---------------------------|--|---|---|------  0    [M]    COG3774 Mannosyltransferase OCH1 and related enzymes
------------------------------------------|----------||-------|---  0    [S]    COG3779 Uncharacterized protein conserved in bacteria
------------------||----------------------|||-|--------|------|---  0    [S]    COG3781 Predicted membrane protein
------------------||-|---------------------|||-------------|---|--  0    [P]    COG3793 Tellurite resistance protein
-------------------------------------------------|-----|---||-||--  0    [S]    COG3795 Uncharacterized protein conserved in bacteria
---------------------------||----|-|-----------------------||-||--  0    [S]    COG3797 Uncharacterized protein conserved in bacteria
---------------------|----------------------------------------||--  0    [S]    COG3798 Uncharacterized protein conserved in bacteria
---|---------------------------------------||-----------------|---  0    [E]    COG3799 Methylaspartate ammonia-lyase
---------------------------||---------------------------------||--  0    [S]    COG3801 Uncharacterized protein conserved in bacteria
--------|------------------||---------------------------------|---  0    [S]    COG3804 Uncharacterized conserved protein related to dihydrodipicolinate reductase
-------------------|----------------------------|-------------|---  0    [Q]    COG3805 Aromatic ring-cleaving dioxygenase
------------------------------------------------|------|------||--  0    [T]    COG3806 Anti-sigma factor
----------|-----------------------------------------------|---||--  0    [S]    COG3809 Uncharacterized protein conserved in bacteria
----------------------------------------------|--|----------|-||--  0    [S]    COG3811 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|------||--  0    [S]    COG3812 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||-||--  0    [S]    COG3813 Uncharacterized protein conserved in bacteria
----------------------------------------------------|---------||--  0    [R]    COG3818 Predicted acetyltransferase, GNAT superfamily
-------------------------------------------------|---------||-||--  0    [S]    COG3821 Predicted membrane protein
-------------------|-----------------------------|-----|------||--  0    [S]    COG3825 Uncharacterized protein conserved in bacteria
---------------------------||--------------------------|------||--  0    [S]    COG3826 Uncharacterized protein conserved in bacteria
-------------------------------------|---------------------||-||--  0    [S]    COG3828 Uncharacterized protein conserved in bacteria
-------------------|||--------------------|||--------------|--|---  0    [S]    COG3831 Uncharacterized conserved protein
--|--------------|--------|||-|---||||-----------|-----|---||-||--  0    [S]    COG3832 Uncharacterized conserved protein
-------------------|----------|-----------------|------|----|-||--  0    [S]    COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain
----------------------------------------------------|--|---||-||||  0    [U]    COG3838 Type IV secretory pathway, VirB2 components (pilins)
---------------------------------|------------------|--|||-|--|---  0    [U]    COG3843 Type IV secretory pathway, VirD2 components (relaxase)
---|---------|-------|---------------------------|-----|------|---  0    [E]    COG3844 Kynureninase
----------------------------------------------------|--|||-|--|---  0    [U]    COG3846 Type IV secretory pathway, TrbL components
-------------------------------------------------|-|---|---||-||--  0    [U]    COG3847 Flp pilus assembly protein, pilin Flp
--------------------------|---||--||-------------|-----|---||-|---  0    [S]    COG3865 Uncharacterized protein conserved in bacteria
-------------------|-|--------|---|||----------------------|------  0    [R]    COG3871 Uncharacterized stress protein (general stress protein 26)
------------------------------|------|--------------------|-|-----  0    [Q]    COG3882 Predicted enzyme involved in methoxymalonyl-ACP biosynthesis
--|-----|---------------------------------------------------|-|---  0    [R]    COG3894 Uncharacterized metal-binding protein
---------------------------||-------------------------------|-|---  0    [V]    COG3896 Chloramphenicol 3-O-phosphotransferase
--------------|----||--------||-|---------------------------|-|---  0    [R]    COG3899 Predicted ATPase
------------------|-----------------------------------------|-|---  0    [S]    COG3900 Predicted periplasmic protein
---------------------------|||------------------------------|-|---  0    [R]    COG3903 Predicted ATPase
-------------------------------------------------|----------|-|---  0    [S]    COG3904 Predicted periplasmic protein
-------------------------------------------------|--|------||-||--  0    [K]    COG3905 Predicted transcriptional regulator
-------------------------------------------------|---||----||-|---  0    [C]    COG3909 Cytochrome c556
--|-----------------------|----------|---------------------|--|---  0    [R]    COG3910 Predicted ATPase
------------------------------------------------|----------|--||--  0    [R]    COG3911 Predicted ATPase
-------------------------------------------------|-----|---|--|---  0    [S]    COG3913 Uncharacterized protein conserved in bacteria
------------------||---------------------------------------|---|--  0    [O]    COG3914 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family
------------------------------------------------||---------|------  0    [S]    COG3915 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-----|---||-|---  0    [T    Q]    COG3916 N-acyl-L-homoserine lactone synthetase
-------------------------------------------------|-----|---|---|--  0    [Q]    COG3917 2-hydroxychromene-2-carboxylate isomerase
---------------------------||------------------------------|--|---  0    [S]    COG3918 Predicted membrane protein
-------------------------------|---------------------------|--|---  0    [R]    COG3919 Predicted ATP-grasp enzyme
------------------------------------------------||---------||-----  0    [S]    COG3930 Uncharacterized protein conserved in bacteria
------------------||---------------------------------------||--|--  0    [R]    COG3932 Uncharacterized ABC-type transport system, permease components
----------------------------------------------|-|-----------|-----  0    [R]    COG3950 Predicted ATP-binding protein involved in virulence
----------------------||----------------------------|------|--|---  0    [S]    COG3952 Predicted membrane protein
------------------------------------------|||||-|-----------|-----  0    [C]    COG3954 Phosphoribulokinase
-|--||-|--|||----|--|------------|-----------||------------||-|---  0    [G]    COG3958 Transketolase, C-terminal subunit
-|--||-|--|||----|--|------------|-----------||------------||-|---  0    [G]    COG3959 Transketolase, N-terminal subunit
------------------------------------------|||-|--|-----|----|-|---  0    [R]    COG3960 Glyoxylate carboligase
----------------------------------------------|------------|--|---  0    [R]    COG3964 Predicted amidohydrolase
-------------------------------------|-------|--|----------||-----  0    [P]    COG3965 Predicted Co/Zn/Cd cation transporters
-------------------|----------||----|------------------|---||-----  0    [M]    COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
-----------|---------------------------------|-------------||-||--  0    [R]    COG3970 Fumarylacetoacetate (FAA) hydrolase family protein
----------------------------------------------|--|--|------|------  0    [R]    COG3972 Superfamily I DNA and RNA helicases
------------------------|-----|-------------------------------|---  0    [S]    COG3976 Uncharacterized protein conserved in bacteria
--------------------||----|---||||---|----------|--|----------|---  0    [R]    COG3981 Predicted acetyltransferase
------------------------------------------------------|---|-|-----  0    [M]    COG4092 Predicted glycosyltransferase involved in capsule biosynthesis
------------------||---------------------------------------||--|--  0    [S]    COG4094 Predicted membrane protein
-----------------|---------------------------|-----|--------|-----  0    [R]    COG4099 Predicted peptidase
----------------------------------------------------|--|----|-|---  0    [G]    COG4101 Predicted mannose-6-phosphate isomerase
-------------------------------------------------------|---|--||--  0    [S]    COG4102 Uncharacterized protein conserved in bacteria
--|----------------|-------------------------|--||-----|---|--|---  0    [S]    COG4104 Uncharacterized conserved protein
-------------------|----------------------||||---|---------||-|---  0    [P]    COG4107 ABC-type phosphonate transport system, ATPase component
-----------------------------------------------------||----||-||--  0    [R]    COG4111 Uncharacterized conserved protein
------|---||------||-------||-------------------------------|-----  0    [R]    COG4113 Predicted nucleic acid-binding protein, contains PIN domain
-------------------------------------|----|||||-------------|-----  0    [R]    COG4114 Uncharacterized Fe-S protein
-------------------|-------||----||------------------------|-----|  0    [S]    COG4115 Uncharacterized protein conserved in bacteria
------------------||-------||------------------------|------|----|  0    [D]    COG4118 Antitoxin of toxin-antitoxin stability system
---------------------------||-------------------------------|-|---  0    [L    R]    COG4119 Predicted NTP pyrophosphohydrolase
||--------------|-||-|---|----------------|||||-||||---|--|||--|--  0    [S]    COG4121 Uncharacterized conserved protein
--||--------|-|-|-||||----||||||||||||-----------|---||-------|---  0    [R]    COG4122 Predicted O-methyltransferase
---------------------------------------------||--|-----|---||-----  0    [S]    COG4125 Predicted membrane protein
------|------||--------------------------------------------||-|---  0    [E]    COG4126 Hydantoin racemase
----------------------------------------------|--------|---||-|---  0    [G]    COG4130 Predicted sugar epimerase
------------------------------------------|||---|-----------|-----  0    [R]    COG4135 ABC-type uncharacterized transport system, permease component
------------------------------------------|||---|-----------|-----  0    [R]    COG4136 ABC-type uncharacterized transport system, ATPase component
-------------------------------------------|||-----|----------|---  0    [R]    COG4158 Predicted ABC-type sugar transport system, permease component
------------------------------------------|||||-||||-------||-|---  0    [E]    COG4160 ABC-type arginine/histidine transport system, permease component
------------------------------------------|||||-||-----|---||-||--  0    [Q]    COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component
-------------------|-------||-|-------------------|--------|------  0    [S]    COG4185 Uncharacterized protein conserved in bacteria
-|--------------|---------|---------------------------------|-----  0    [R]    COG4186 Predicted phosphoesterase or phosphohydrolase
---------------------|--------|-----|-----------------------|-----  0    [E]    COG4187 Arginine degradation protein (predicted deacylase)
------------------||-----------------|-----------|-----|---|---|--  0    [R]    COG4188 Predicted dienelactone hydrolase
-------------------------------------|---------------------||-|---  0    [K]    COG4189 Predicted transcriptional regulator
---|---------------------------------------------|----------|-----  0    [K]    COG4190 Predicted transcriptional regulator
------------------------------------------------||-----|---||-|---  0    [T]    COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system
---------------------------||-------|-------------------------|---  0    [R]    COG4195 Phage-related replication protein
---------------------------|||-----------------------------|--|---  0    [S]    COG4196 Uncharacterized protein conserved in bacteria
------------------------------------------|||-------|------|------  0    [S]    COG4197 Uncharacterized protein conserved in bacteria, prophage-related
-------------------------------|||-|||---------------------|------  0    [G]    COG4209 ABC-type polysaccharide transport system, permease component
------------------------------------------|||||-||||-------||-|---  0    [E]    COG4215 ABC-type arginine transport system, permease component
------------------------------------------|||-|-----|------|------  0    [L]    COG4220 Phage DNA packaging protein, Nu1 subunit of terminase
------------------||-|-----------------------|------------|||-|---  0    [S]    COG4222 Uncharacterized protein conserved in bacteria
------------------------------|-----||-------||------------|------  0    [R]    COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
-------------------|-|---------------------||-------|--|----|----|  0    [S]    COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters
----------------------------------------------------|------|--|---  0    [L]    COG4227 Antirestriction protein
|-|-|||||-||------------------|------------------------|------||--  0    [C]    COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
------------------------------------------|||||-|-------------|---  0    [M]    COG4238 Murein lipoprotein
----------------|-||-----------------------------|----------|-|---  0    [S]    COG4244 Predicted membrane protein
-----------------------------------------------------------||-||--  0    [S]    COG4246 Uncharacterized protein conserved in bacteria
-------------------|--------------------------------|---------|---  0    [R]    COG4249 Uncharacterized protein containing caspase domain
------------------||-|---------------------------|---------|------  0    [T]    COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase)
------------------||-|---------------------------|-----|----|--|--  0    [T]    COG4252 Predicted transmembrane sensor domain
-------------------------------------------------|-----|----|--|--  0    [S]    COG4254 Uncharacterized protein conserved in bacteria
------------------------------------------|||-|--------|----|-|---  0    [P]    COG4256 Hemin uptake protein
---|---------------|--------------|--|-------|---------|----|-----  0    [Q]    COG4264 Siderophore synthetase component
-------------||----------------------------------|-----|----|-----  0    [F]    COG4266 Allantoicase
---------------------|--------------------|||||--------|---||-----  0    [S]    COG4269 Predicted membrane protein
--------|-|--------------------------------------------|----|-|---  0    [S]    COG4274 Uncharacterized conserved protein
-----|-------------------------------------------------|----|-|---  0    [S]    COG4275 Uncharacterized conserved protein
|-------------------|---------|----------------------------|---|--  0    [R]    COG4277 Predicted DNA-binding protein with the Helix-hairpin-helix motif
-----------|-------|------------------------------------------|---  0    [S]    COG4280 Predicted membrane protein
-------------||------|--------------------------------------|-----  0    [G]    COG4282 Protein involved in beta-1,3-glucan synthesis
-------------|||------||-----------------------------------|------  0    [S]    COG4286 Uncharacterized conserved protein related to MYG1 family
-----------------|-|----------------------------------------|-----  0    [S]    COG4288 Uncharacterized protein conserved in bacteria
-----------------|---------------------------|-------------||-----  0    [S]    COG4289 Uncharacterized protein conserved in bacteria
---------------------|------------||-------------------|---||-----  0    [S]    COG4292 Predicted membrane protein
---------------------|--------------|----------------------||-----  0    [S]    COG4297 Uncharacterized protein containing double-stranded beta helix domain
-------------------|-|----------------------------------------|---  0    [S]    COG4298 Uncharacterized protein conserved in bacteria
---------------------------||--------------------------|---|--|---  0    [S]    COG4307 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---||-|---  0    [S]    COG4312 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|----|-|---  0    [C]    COG4313 Protein involved in meta-pathway of phenol degradation
-------------------------------------------------|-----|---||-----  0    [S]    COG4315 Uncharacterized protein conserved in bacteria
--------------------------------------------------|--||-------|---  0    [S]    COG4316 Uncharacterized protein conserved in bacteria
-------------------------------------|-----------|-----|---||-----  0    [S]    COG4317 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|---|--|---  0    [S]    COG4318 Uncharacterized protein conserved in bacteria
-------------------|----------------|------------|-----|----|-|---  0    [S]    COG4319 Ketosteroid isomerase homolog
----------------------------------------------------|--|------|---  0    [S]    COG4320 Uncharacterized protein conserved in bacteria
-------------------------------------------------|-----|------|---  0    [R]    COG4324 Predicted aminopeptidase
------------------||-------||-------------------------------|-----  0    [S]    COG4328 Uncharacterized protein conserved in bacteria
-------------------|-----------------|----------------------|-----  0    [S]    COG4329 Predicted membrane protein
------------------------------||-------------|----------------|---  0    [S]    COG4331 Predicted membrane protein
------------------------------|---------------|------------|--|---  0    [S]    COG4332 Uncharacterized protein conserved in bacteria
----------------------------------|--------||---------------|-----  0    [S]    COG4333 Uncharacterized protein conserved in bacteria
-------------------------------|--------------------|-------|-----  0    [S]    COG4334 Uncharacterized protein conserved in bacteria
------------------------------------|--------------|-------|------  0    [L]    COG4335 DNA alkylation repair enzyme
--------------|-----------|---------|------------|---------|------  0    [S]    COG4336 Uncharacterized conserved protein
-------------------|-----------------------------|------------|---  0    [S]    COG4339 Uncharacterized protein conserved in bacteria
-------------------|-----------------------------|-----|------|---  0    [R]    COG4341 Predicted HD phosphohydrolase
----------------------------------------------|--|--|--|---|------  0    [R]    COG4385 Bacteriophage P2-related tail formation protein
---------------------|----|||--|---------------------------||-||--  0    [S]    COG4420 Predicted membrane protein
---------------------------||-------------------------------|-|---  0    [S]    COG4422 Bacteriophage protein gp37
---------------------------||-------------------------------|-|---  0    [S]    COG4423 Uncharacterized protein conserved in bacteria
---------------------------||-------------------------------|-|---  0    [S]    COG4424 Uncharacterized protein conserved in bacteria
--------------------------|||------------------------------||-|---  0    [S]    COG4425 Predicted membrane protein
---------------------------||------------------------------||--|--  0    [S]    COG4427 Uncharacterized protein conserved in bacteria
-------------------|--------------||||----------------------|-||--  0    [S]    COG4430 Uncharacterized protein conserved in bacteria
------------------||----------------------------------------|-----  0    [C]    COG4451 Ribulose bisphosphate carboxylase small subunit
--------------------|---------------------|||||--|---------|------  0    [V]    COG4452 Inner membrane protein involved in colicin E2 resistance
---------------------------||--------------||-|-|-|-|--|----|-----  0    [S]    COG4453 Uncharacterized protein conserved in bacteria
------------|------|----------------------------||---------||-|---  0    [P]    COG4454 Uncharacterized copper-binding protein
---------------------------------------------||--|---------|------  0    [R]    COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion
------------------|---------------------------|---|-|-------|-||--  0    [S]    COG4456 Virulence-associated protein and related proteins
---------------------------------------------||----|----------|---  0    [S]    COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor
---------------------------------------------||----|----------|---  0    [S]    COG4458 Uncharacterized protein conserved in bacteria, putative virulence factor
------------------------------------------------||---------||-----  0    [C]    COG4459 Periplasmic nitrate reductase system, NapE component
----------------------------------------------|--|------------|---  0    [S]    COG4460 Uncharacterized protein conserved in bacteria
---------------------------||----------------||--|---------|--|---  0    [S]    COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein
--------------------------------||----|-||--------------|||---|---  0    [S]    COG4487 Uncharacterized protein conserved in bacteria
------------------------------------------||||---|----------|-|---  0    [P]    COG4521 ABC-type taurine transport system, periplasmic component
------------------------------------------||||---|---------||-|---  0    [P]    COG4525 ABC-type taurine transport system, ATPase component
---|-------------------------------------------------------|---|--  0    [S]    COG4538 Uncharacterized conserved protein
------------------------------|----|----------|---------------|---  0    [Q]    COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase
-------------------|-----------------------------|-----|------|---  0    [R]    COG4551 Predicted protein tyrosine phosphatase
-------------------------------------------------------|---||-||||  0    [I]    COG4553 Poly-beta-hydroxyalkanoate depolymerase
---------------------|----|----------------|||--||-|-------||-|---  0    [P]    COG4558 ABC-type hemin transport system, periplasmic component
---------------------|----|----------------|||--||---------||-|---  0    [P]    COG4559 ABC-type hemin transport system, ATPase component
------------------------------------------|||||------------|--|---  0    [M]    COG4571 Outer membrane protease
------------------------------------------|||||--------|---||-|---  0    [G]    COG4573 Predicted tagatose 6-phosphate kinase
--------------------------||||-------|----|||-|----|----------|---  0    [K]    COG4578 Glucitol operon activator
--|------------------------||-----||-|-----|||---------|---||-|---  0    [L]    COG4584 Transposase and inactivated derivatives
------------------||-|----|||-||||||||-----------|-----|---||-||--  0    [T]    COG4585 Signal transduction histidine kinase
-------------------------------------------||---|---------|-|-----  0    [R]    COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain
--------------------|---------------------||||--||-|--------|-----  0    [R]    COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase
------------------------------------------|||||-||---------||-|---  0    [E]    COG4598 ABC-type histidine transport system, ATPase component
----------------|----------------------------|---|---------||-||||  0    [R]    COG4618 ABC-type protease/lipase transport system, ATPase and permease components
--------------------|----------------------------|--|--|---|--|---  0    [S]    COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain
------------------------------||--||------|||-----------------|---  0    [R]    COG4626 Phage terminase-like protein, large subunit
--|----------------------------|----------|||||-|--|----------|---  0    [C    H]    COG4635 Flavodoxin
-------------------|-----------------------------|----------|-----  0    [R]    COG4637 Predicted ATPase
------------------------------|-----||----------------------|-----  0    [S]    COG4641 Uncharacterized protein conserved in bacteria
------------------|-------------||---------------|---||-------|---  0    [S]    COG4642 Uncharacterized protein conserved in bacteria
---------------------|--------|--------------|-------------|--|---  0    [L]    COG4644 Transposase and inactivated derivatives, TnpA family
---------------------------------------------------------|-|--|---  0    [K    L]    COG4646 DNA methylase
--------------------------------------------------------||--|-|---  0    [Q]    COG4647 Acetone carboxylase, gamma subunit
---------------------------||--------------||----------|---|--||--  0    [R]    COG4653 Predicted phage phi-C31 gp36 major capsid-like protein
-------------------------------------------------|-----|---||-|---  0    [S]    COG4655 Predicted membrane protein
----------------------||-------------------||||--|-----|------|---  0    [U]    COG4669 Type III secretory pathway, lipoprotein EscJ
------------------||---------------------------------------||-|---  0    [R]    COG4671 Predicted glycosyl transferase
------------------||-|----|----------|-------|---|-----|---||-|---  0    [R]    COG4674 Uncharacterized ABC-type transport system, ATPase component
-------------------|-----------------------------------|------|---  0    [S]    COG4675 Microcystin-dependent protein
-------------------|----------------------|||-|-------------|-|---  0    [S]    COG4680 Uncharacterized protein conserved in bacteria
------------------------------|------------------------|------|---  0    [Q]    COG4689 Acetoacetate decarboxylase
---------------------------||-----------------------|-------|-----  0    [R]    COG4691 Plasmid stability protein
----------------------------------------------|---------||-||-----  0    [G]    COG4692 Predicted neuraminidase (sialidase)
-------------------|-----------------------------------|------|---  0    [S]    COG4705 Uncharacterized membrane-anchored protein conserved in bacteria
----------------------------------------------------|-----||------  0    [R]    COG4710 Predicted DNA-binding protein with an HTH domain
---|----|-------|--|---------------------------------------||-----  0    [S]    COG4711 Predicted membrane protein
--|-------------------------------|||-----------------------|-----  0    [S]    COG4717 Uncharacterized conserved protein
-------------------|-|--------------------------------------|-----  0    [S]    COG4719 Uncharacterized protein conserved in bacteria
-------------|-----|----------------------------------------|-----  0    [T    K]    COG4725 Transcriptional activator, adenine-specific DNA methyltransferase
-------------------|-------------------------|-------------|------  0    [R]    COG4734 Antirestriction protein
------------------------------------------------|-----|||||-|-||--  0    [O]    COG4736 Cbb3-type cytochrome oxidase, subunit 3
-------------------|-----------------------||-|------|||----|-----  0    [S]    COG4737 Uncharacterized protein conserved in bacteria
--------------------------|---------------|||-----------------|---  0    [S]    COG4763 Predicted membrane protein
--------------------|--------------|------|||-|------------|------  0    [E]    COG4766 Ethanolamine utilization protein
------------------------------------------|||||-||--------||------  0    [P]    COG4771 Outer membrane receptor for ferrienterochelin and colicins
------------------------------------------|------|------||--|--|--  0    [P]    COG4772 Outer membrane receptor for Fe3+-dicitrate
-------------------|----------------------||||---|---------||-|---  0    [P]    COG4778 ABC-type phosphonate transport system, ATPase component
--------------------------|---------------|||||-||---------|------  0    [P]    COG4779 ABC-type enterobactin transport system, permease component
----------------------||-------------------||||--|-----|------|---  0    [U]    COG4789 Type III secretory pathway, component EscV
-------------------------------------------||||--|-----|------|---  0    [U]    COG4790 Type III secretory pathway, component EscR
----------------------||-------------------||||--|-----|------|---  0    [U]    COG4791 Type III secretory pathway, component EscT
-------------------------------------------||||--|------------|---  0    [U]    COG4792 Type III secretory pathway, component EscU
----------------------||-------------------||||--|-----|------|---  0    [U]    COG4794 Type III secretory pathway, component EscS
-------------------|------------------------------------------||--  0    [R]    COG4798 Predicted methyltransferase
-----------------------------------|----------------|---------|---  0    [S]    COG4834 Uncharacterized protein conserved in bacteria
-------------------------------|---|-----------------------|--|---  0    [S]    COG4852 Predicted membrane protein
--------------------|---------------|-----------------------|-|---  0    [R]    COG4857 Predicted kinase
--------------------------|------|-------------------------|------  0    [S]    COG4877 Uncharacterized protein conserved in bacteria
---------------------------------|-|------------------------|-----  0    [S]    COG4898 Uncharacterized protein conserved in bacteria
-----------------------------------|----------|---------------|---  0    [Q]    COG4909 Propanediol dehydratase, large subunit
-----------------------------------|----------|---------------|---  0    [Q]    COG4910 Propanediol dehydratase, small subunit
--|-----------------|-----|----|---|------------------------|-|--|  0    [L]    COG4912 Predicted DNA alkylation repair enzyme
--------------------|------------|---------------------|---|------  0    [S]    COG4922 Uncharacterized protein conserved in bacteria
--|--------------|--------------------------------------------|---  0    [S]    COG4923 Uncharacterized conserved protein
--------------------|-------------|-------------------------|-----  0    [R]    COG4927 Predicted choloylglycine hydrolase
-|---------------|-|-|----|-------------------|------------|------  0    [R]    COG4928 Predicted P-loop ATPase
-------------------------------------------------|-----|----|-||--  0    [K]    COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain
---------------------------------|-------------------------|--|---  0    [S]    COG4947 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------||-||--  0    [S]    COG4949 Uncharacterized membrane-anchored protein conserved in bacteria
--------------------------|---------------|||||--------|---||-----  0    [S]    COG4950 Uncharacterized protein conserved in bacteria
-----------------|-----------------------------------------||-|---  0    [M]    COG4952 Predicted sugar isomerase
-------------------||---------------------|||-|----||------||-||-|  0    [M]    COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC
-------------------------------------------------------|---|--|---  0    [S]    COG4954 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|---|--|---  0    [O    U]    COG4959 Type IV secretory pathway, protease TraF
---------------------------------------------|---|-|---|---||-||--  0    [O    U]    COG4960 Flp pilus assembly protein, protease CpaA
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG4961 Flp pilus assembly protein TadG
||----||-|----------------|||-|--------------|---|-||--|---||-||--  0    [U]    COG4962 Flp pilus assembly protein, ATPase CpaF
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG4963 Flp pilus assembly protein, ATPase CpaE
---------------------|---------------------------|-|---|---||-||--  0    [U]    COG4964 Flp pilus assembly protein, secretin CpaC
--------------------------|||----------------|---|-|---|---||-||--  0    [U]    COG4965 Flp pilus assembly protein TadB
------------------------------------------------||--||||------|---  0    [N    U]    COG4970 Tfp pilus assembly protein FimT
--||-------------------------------|--------------------------|---  0    [S]    COG4983 Uncharacterized conserved protein
------------------------------|--|||||----|||||-|----------|--|---  0    [R]    COG4989 Predicted oxidoreductase
------------------------------------------|||-|--|---------||-|---  0    [G]    COG4993 Glucose dehydrogenase
-------------------------------------------------------|---|---|--  0    [T]    COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain
---------------------|----|---------------|||||-||-----|------||--  0    [R]    COG5006 Predicted permease, DMT superfamily
---------------------------------------------|---|-|---|---||-||--  0    [U]    COG5010 Flp pilus assembly protein TadD, contains TPR repeats
|-|-----|-----------|---------------------------------------|-|---  0    [R]    COG5012 Predicted cobalamin binding protein
-------------||--------------------------------------------|------  0    [K]    COG5108 Mitochondrial DNA-directed RNA polymerase
---------------------------------|-------------------------|--||--  0    [S]    COG5255 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---|--||--  0    [S]    COG5267 Uncharacterized protein conserved in bacteria
----------------------------------------------------|--|---|--|---  0    [N    U]    COG5268 Type IV secretory pathway, TrbD component
-------------------|-|---------------|-----------------|---|--||--  0    [T]    COG5278 Predicted periplasmic ligand-binding sensor domain
-------------|-----|-------||--------------------------|----|-|---  0    [Q]    COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin
---------------------------||--------------||-|-------------|-|---  0    [R]    COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid
----------------------------------------------------|--|---|--|---  0    [U]    COG5314 Conjugal transfer/entry exclusion protein
-------------------|---------------------------------------||-|---  0    [S]    COG5331 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---||-|---  0    [S]    COG5343 Uncharacterized protein conserved in bacteria
-------------------------------------------------|---------|--|---  0    [S]    COG5351 Uncharacterized protein conserved in bacteria
--|--------------------------------|-------------------|----|-||--  0    [S]    COG5361 Uncharacterized conserved protein
--|--------------------------------|--------------------------|--|  0    [R]    COG5362 Phage-related terminase
----------------------------------------------------|------||-|---  0    [S]    COG5368 Uncharacterized protein conserved in bacteria
---------------------------------------------|---|-----|---||-|---  0    [S]    COG5373 Predicted membrane protein
----------------------------------------------------|------||-|---  0    [I]    COG5379 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase
------------------|-----------------------------------------|-|---  0    [S]    COG5381 Uncharacterized protein conserved in bacteria
-------------------------------------------------------|---||-||--  0    [S]    COG5394 Uncharacterized protein conserved in bacteria
-----------------------------------------------------------||-||--  0    [S]    COG5397 Uncharacterized conserved protein
---------------------|--------------------------------------|-|---  0    [S]    COG5403 Uncharacterized conserved protein
---------------------------------------------|---------|------||--  0    [S]    COG5419 Uncharacterized conserved protein
-------------------|----------------------------------------|-|---  0    [S]    COG5420 Uncharacterized conserved small protein containing a coiled-coil domain
----|------|----------||-------------------------|----------|----|  0    [H]    COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C
----------------------------------------------|------------|--|---  0    [S]    COG5426 Uncharacterized membrane protein
---------------------------------------------|---|-----|---|--|--|  0    [S]    COG5430 Uncharacterized secreted protein
-------------------|------------|---------|||---------------|-----  0    [L]    COG5433 Transposase
-------------|---|------------|------------------------|---|---|--  0    [M]    COG5434 Endopolygalacturonase
------------------|-----------------------------------------|-|---  0    [S]    COG5439 Uncharacterized conserved protein
---------------------------|||-----------------------------|---|--  0    [K]    COG5450 Transcription regulator of the Arc/MetJ class
-------------------------------------|-------|-------------|---|--  0    [S]    COG5460 Uncharacterized conserved protein
-----------------------------------------------------------||-||--  0    [N]    COG5461 Type IV pili component
------------------------------------------|||||------------|---|--  0    [S]    COG5463 Predicted integral membrane protein
--|-||-----|-----------------------------------------------||-|---  0    [S]    COG5466 Predicted small metal-binding protein
------------------||---------------------------------------|--|---  0    [S]    COG5469 Predicted metal-binding protein
-------------------------------------------||-|-----|------|------  0    [S]    COG5471 Uncharacterized conserved protein
-----------------------------------------------------------||-|---  0    [S]    COG5473 Predicted integral membrane protein
------------------------------------------|||-|------------|--|---  0    [S]    COG5475 Uncharacterized small protein
-------------------------------------------------------|---||-|---  0    [S]    COG5477 Predicted small integral membrane protein
-------------||----------------------------------|---------||-|---  0    [S]    COG5478 Predicted small integral membrane protein
------------------------------|----------------------------||-|---  0    [S]    COG5482 Uncharacterized conserved protein
-------------------|-----------------------------|-----|---||-|---  0    [R]    COG5485 Predicted ester cyclase
-------------------------------------------------------|----|-|---  0    [S]    COG5486 Predicted metal-binding integral membrane protein
-------------------------------------------------------|---||-||--  0    [S]    COG5489 Uncharacterized conserved protein
------------------------------------------------------------|-||--  0    [S]    COG5490 Uncharacterized conserved protein
---------------------|--||----------------------------------|-|---  0    [S]    COG5497 Predicted secreted protein
-------------------|----------------------|||-|-------------|-|---  0    [K]    COG5499 Predicted transcription regulator containing HTH domain
-------------------|----------------------------------------|-|---  0    [S]    COG5500 Predicted integral membrane protein
----------------|--------------------------------------|----|-----  0    [S]    COG5501 Predicted secreted protein
----------------|--|----------------------------------------|-|---  0    [S]    COG5502 Uncharacterized conserved protein
------------------------------------------|||---------------|-|---  0    [S]    COG5507 Uncharacterized conserved protein
-------------------------------------------------------|----|-|---  0    [R]    COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding
-------------------|------------------------------------------||--  0    [S]    COG5526 Uncharacterized conserved protein
-------------------------------------------------|----------|--|--  0    [S]    COG5528 Predicted integral membrane protein
---------------------|--------------------------------------|-|---  0    [S]    COG5530 Predicted integral membrane protein
---------------------|---------------------------------|------|---  0    [L]    COG5534 Plasmid replication initiator protein
----------------------------|-------------------------------|-|---  0    [S]    COG5552 Uncharacterized conserved protein
-------------------|-----------------------------|------------|---  0    [R]    COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily
-------------------|----------------------------------------|-|---  0    [Q]    COG5554 Nitrogen fixation protein
-------------------|----------------------------------------|-|---  0    [N]    COG5555 Cytolysin, a secreted calcineurin-like phosphatase
---------------------------------------------|--------------|-|---  0    [S]    COG5556 Uncharacterized conserved protein
--|----------------|---|-----------------------------------|------  0    [S]    COG5563 Predicted integral membrane proteins containing uncharacterized repeats
---------------------------------------------|--------------|-|---  0    [R]    COG5564 Predicted TIM-barrel enzyme, possibly a dioxygenase
----------------------------------------------------|-------|-|---  0    [R]    COG5565 Bacteriophage terminase large (ATPase) subunit and inactivated derivatives
------------------------------------------|||----------|---||-----  0    [S]    COG5569 Uncharacterized conserved protein
-------------------------------------------------------|----|--|--  0    [S]    COG5572 Predicted integral membrane protein
------------|------|-----------------------------------|----|-----  0    [R]    COG5573 Predicted nucleic-acid-binding protein, contains PIN domain
---------------------------||-------------------------------|-|---  0    [S]    COG5579 Uncharacterized conserved protein
-------------------------------------------------------|----|-|---  0    [S]    COG5588 Uncharacterized conserved protein
------------------------------------------------|-----------|--|--  0    [S]    COG5589 Uncharacterized conserved protein
-------------||---------------------------------------------|-----  0    [M]    COG5597 Alpha-N-acetylglucosamine transferase
--|---------------------------------------------------------|-|---  0    [H]    COG5598 Trimethylamine:corrinoid methyltransferase
-------------------------------------------------------|----|-|---  0    [S]    COG5605 Predicted small integral membrane protein
--|--------|------||-----------------------------|-----|----|-----  0    [S]    COG5607 Uncharacterized conserved protein
----------------|-------------------------------------------|----|  0    [R]    COG5611 Predicted nucleic-acid-binding protein, contains PIN domain
-----------------------------------------------------------|--||--  0    [S]    COG5612 Predicted integral membrane protein
------------------------------|------------||----------|---|------  0    [R]    COG5614 Bacteriophage head-tail adaptor
------------------------------------------------|-----------|-|---  0    [S]    COG5616 Predicted integral membrane protein
-------------------------------------------------|--|------|------  0    [S]    COG5619 Uncharacterized conserved protein
------------------------------|----------------------------|--|---  0    [S]    COG5620 Uncharacterized conserved protein
---------------------|-----||-------------------|----------|------  0    [R]    COG5621 Predicted secreted hydrolase
-----------------------------------------------------------||-|-||  0    [N]    COG5622 Protein required for attachment to host cells
--|---------------||------------------------------------------|---  0    [T]    COG5635 Predicted NTPase (NACHT family)
-------------------------------------------------------|------||--  0    [S]    COG5639 Uncharacterized conserved small protein
------------------------------------------------|-----------|-|---  0    [O]    COG5640 Secreted trypsin-like serine protease
---------------------------------------------|--------------|-|---  0    [S]    COG5642 Uncharacterized conserved protein
-------------------------------------------------------|----|-|---  0    [S]    COG5649 Uncharacterized conserved protein
-----------------------------------------------------------||-||--  0    [M]    COG5653 Protein involved in cellulose biosynthesis (CelD)
---------------------------||----------------|--------------|-|---  0    [S]    COG5654 Uncharacterized conserved protein
------------------|------------------------------------|------|---  0    [L]    COG5659 FOG: Transposase
------------------||----|--||-------||-----------------|---||-|---  0    [K]    COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor)
------------------------------|-----||------------------------|---  0    [S]    COG5663 Uncharacterized conserved protein

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