| (Pae) Pseudomonas aeruginosa | ||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| generin.cgi | Functional categories | |||||||||||||||||||||||||||||||||
| Fun | All | J | A | K | L | B | D | Y | V | T | M | N | Z | W | U | O | C | G | E | F | H | I | P | Q | R | S | ||||||||
| COGs | 2,241 | 144 | 2 | 85 | 100 | 1 | 27 | - | 23 | 87 | 121 | 73 | - | - | 90 | 103 | 155 | 96 | 204 | 66 | 125 | 59 | 154 | 52 | 286 | 362 | ||||||||
| proteins | 4,893 | 200 | 2 | 520 | 159 | 3 | 33 | - | 73 | 428 | 270 | 156 | - | - | 176 | 195 | 338 | 258 | 601 | 107 | 193 | 248 | 381 | 217 | 763 | 495 | ||||||||
| Distribution of COGs by number of proteins | ||||||||||||||||||||||||||||||||||
| proteins | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 17 | 18 | 19 | 20 | 21 | 24 | 26 | 28 | 29 | 30 | 32 | 34 | 37 | 40 | 45 | 49 | 54 | 70 | 121 |
| COGs | 1470 | 372 | 165 | 67 | 44 | 26 | 20 | 11 | 14 | 7 | 5 | 4 | 5 | 1 | 2 | 2 | 4 | 1 | 1 | 4 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Co-ocurrences in sister taxa | No sister genomes in order Pseudomonadales |
|---|
+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ++ + + + + + + + + + + + + + + + + ||------||------|-||||----||||||||||||----|||||-||||||||--||||||-- 121 [K] COG0583 Transcriptional regulator ||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 70 [G E P R] COG0477 Permeases of the major facilitator superfamily -----------------||||-----|||-||-|||||----|||||-||||||||--||||||-- 54 [K] COG2207 AraC-type DNA-binding domain-containing proteins |-||----|----||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 49 [T] COG0642 Signal transduction histidine kinase --|||||||-||||||||||||||--||||||||||||----|||||||||||||||||||||||| 45 [I Q R] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) |-||---||--|----||||||----|||||||||||||---|||||-||||||||--||||||-- 40 [K] COG1309 Transcriptional regulator |||||||||||||||||||||||||-||||||||||||----|||||||||||||||||||||||| 37 [Q R] COG0500 SAM-dependent methyltransferases ---|||--|-||||-----|||----|||||---|-||----|||||-||---|||---|||||-- 34 [I] COG1960 Acyl-CoA dehydrogenases |-||--|||----|||-|||-|--||-||-|----|||----|||||-|||||--|||||||||-- 32 [T] COG0784 FOG: CheY-like receiver ----------------||||-|--|-|||||---||||----|||||-||--|--|---|||||-- 30 [T] COG2199 FOG: GGDEF domain |-||----|-----|-||||-|||-||||||----|||----|||||-||--|--|--||||||-- 30 [T] COG2202 FOG: PAS/PAC domain --||||--|-|||||||-||||---|||||||-||||||||||||||-|||||||||||||||||| 29 [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) --|-----|-|-|----||||||||-||||||||||||----|||||-||||-||||||||||||| 28 [E T] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain --||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 26 [N T] COG0840 Methyl-accepting chemotaxis protein ----------------||||||||--||||||||||||----|||||-|||||||||||||||||| 24 [T K] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ----------------|-|||---------------------|||||-||||||||||||||||-- 24 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport |-|||||||-|||||||||||||||-|||-||-|||||----|||||||||||||||||||||||| 21 [G E R] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily ----------------||||||--|||---|-||||||----|||||-|||||||||||||||||| 21 [M] COG0845 Membrane-fusion protein ||||||---||||||-|-||||----|||||||||||||---|||||-||-|-|||||||||||-| 21 [C] COG1012 NAD-dependent aldehyde dehydrogenases -------------||----|------||||-||||||-----|||||-||-----|--||-||--- 21 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins ----------------|-||-|---||||||----|||----|||||-||--|--|---||||||| 20 [T] COG2200 FOG: EAL domain |||||||||-||||||||||||||--|||||||||||||---|||||-||||||||||||||||-| 19 [K R] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ||||||||||||||||||||||---|||||||||||||----|||||-|||||||||||||||||| 18 [M] COG0438 Glycosyltransferase --|||||||-|||||-|-||-|||-|||||||||-|||----|||||-||||||||||||||||-- 18 [E] COG0665 Glycine/D-amino acid oxidases (deaminating) ----------------|-|||---------------------|||||-|||||||||||||||||| 18 [M U] COG1538 Outer membrane protein -----------------|||||--|-||||||--||||----|||||-||||||||---|||||-- 18 [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog -------------||---||------------||--------|||||-||||||||---||||||| 17 [O] COG0625 Glutathione S-transferase ---|||--|-|||||-|--|||----|||||-|||-||----|||||-||--|--|---||||||| 17 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase |-|-------|-----||-|||--|-|||-||||||||----|||||-||||||||---||||||| 16 [K] COG1396 Predicted transcriptional regulators ------------------||-|----|||-||||||||----|||||-||||||||---|||||-- 16 [T K] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain --|-----|---------||-|----||||------||----------||---|||||||||||-- 14 [C] COG2010 Cytochrome c, mono- and diheme variants |-||--|||--||||---||||----||||||||||||----|||||-||||||||--||||||-- 13 [E] COG0346 Lactoylglutathione lyase and related lyases ||||||--||||||||--|||-||--|||||||||||||||||||||-|||||--|---||||||| 13 [E] COG0531 Amino acid transporters ---|----|-|-|----|||||--||----||||||--|||||||||-||||-|||---|||||-- 13 [E] COG0687 Spermidine/putrescine-binding periplasmic protein |||||||||||||----|-|||----||||||||||||----|||||-||--||||---|||||-- 13 [K] COG1846 Transcriptional regulators ------------------------------------------|------|-----|---||--|-- 13 [P T] COG3712 Fe2+-dicitrate sensor, membrane component |||||||||||||||-||||||--|||||-||||||-|-||||||||-||-|---|---|||||-- 12 [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases -||-----||---||--|||||||--|---|--||-||----||||--||||---|---|||||-- 12 [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components --|-------------||||||---|----|---|-||----|||||-|||||||||||||||||| 12 [V] COG0841 Cation/multidrug efflux pump |||||||||||||--------|----|||-|-----||----|||||-||||-|||---|||||-- 12 [K] COG1522 Transcriptional regulators ||||||||||||||||--|-||---||||||||-||||----|||||-|||----|||-||||||| 11 [I] COG0183 Acetyl-CoA acetyltransferase |-|-||--|||||----||--|----|---------||----|||||-|||||--|--||||||-- 11 [E] COG1280 Putative threonine efflux protein --|||||||||||||-||-|-|--|||||-||||||||----|||||-||--||||--||||||-- 11 [Q] COG1335 Amidases related to nicotinamidase ||||----||-|-------|-|----||||--||||||-|--|||||--|--|--|---|||||-- 11 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ---------||-------||-|----||||||--||||----|||||-||-----|---|||||-- 11 [K] COG2771 DNA-binding HTH domain-containing proteins ||||||||||||-||-||||||---|||||||-|||||----|||||-||||||||||||||||-- 10 [M G] COG0451 Nucleoside-diphosphate-sugar epimerases --|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 10 [E] COG0765 ABC-type amino acid transport system, permease component --||||--|--|-||--|-|||----|||-|||-||||-|--|||||-||--|--|---|||||-- 10 [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family --|||||||-||--|-|----|----|||--|||||||----|||||-||||---|||||||||-- 10 [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism ----------------|---|-||||-----------|----|||||-||-||||||||||||||| 10 [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ----------------|--||-||||-||-------------|||||||||||||||||||||||| 10 [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins -------------------|-----------------------||||-||-----|---|--|--- 10 [S] COG3501 Uncharacterized protein conserved in bacteria |||-||-||||||||-||||-|----||||||-|||||----||||||||||||||--||||||-- 9 [E H] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] ---|--||--|||||-||||||----||||||||||||----||||||||||||||||||||||-- 9 [J] COG0251 Putative translation initiation inhibitor, yjgF family |-||||--|-|||||---||-|||--||||-||-||||----|||||-||||||||--|||||||| 9 [I Q] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II ||||||||||||||||||||||---||||||||||||||||||||||-|||||||||||||||||| 9 [M] COG0463 Glycosyltransferases involved in cell wall biogenesis |-||||--|-|||||||||||||||-||||||||||||----|||||||||||||||||||||||| 9 [L R] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes |||||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||| 9 [O C] COG0526 Thiol-disulfide isomerase and thioredoxins --||||----||-||-|--|-|----||||-|--||||----|||||-||-||--|---|||||-- 9 [C R] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases --|-----|-------|-||||----||||||||||||----|||||-|||||||||||||||||| 9 [K] COG0789 Predicted transcriptional regulators ----||||--|||||--|-|||----|||||-||||||----|||||-||-|---|---|||||-- 9 [K E] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ---|------------||---|----|||-------||----|||||-||||---|--||||||-- 9 [K] COG1414 Transcriptional regulator ----------------|-----------------|-|-----|||||-|||--|||---||||||| 9 [V] COG1566 Multidrug resistance efflux pump ----------------||||||||------||||||||----|||||-|||||--|--|---||-- 9 [N U] COG2165 Type II secretory pathway, pseudopilin PulG --|-||--|----||---||||----|||--|||||-|||--|||||-|||--|||---|||||-- 9 [L] COG2801 Transposase and inactivated derivatives --------------------------|||--|--||||----|||||--||||--||||||-|--- 9 [G] COG2814 Arabinose efflux permease |||||||||||||||-||||-|----||||-|||||||----|||||-|||||||||||||||||| 8 [E] COG0174 Glutamine synthetase --||||--|-|||||-|-||||----|||||-----||----|||||-||||||||||||||||-- 8 [C] COG0277 FAD/FMN-containing dehydrogenases |-|||||||-|||||-||||-|--|-|||||--|||||----|||||-||--||||||||||||-- 8 [R] COG0388 Predicted amidohydrolase ||||||||||||||||||||||----||||||||||||----||||||||||||||||||||||-- 8 [R] COG0491 Zn-dependent hydrolases, including glyoxylases |------------||||||||||||||||||||||||||-|||||||-|||||||||||||||||| 8 [O] COG0542 ATPases with chaperone activity, ATP-binding subunit |||||||||||||-|-|-||-|----||||-|||||||----|||||-||||-|||---||||||| 8 [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins -||-----||-------|||||||--|---|--||-||----||||---|||---|---|||||-- 8 [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component |||||||||||||---||||||----|--|||--||||----|||||-||||||||||||||||-- 8 [R] COG0730 Predicted permeases ----------------||||||--||||||||--||||----|||||||||||||||||||||||| 8 [M] COG0739 Membrane proteins related to metalloendopeptidases -|||||-|-----||--|-|||----||||||||||||--|-|||||-||-|-||||||||||||| 8 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins ----|------|-----|--||----|||-|||-||||----|||||-||---|||---|||||-- 8 [K] COG1802 Transcriptional regulators -------------||||||||||||||||||||||||||||||||||-|||||||||||||||||| 7 [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase |||||||||||||||-||||||--||||||||||---|-|--|||||||||||||||||||||||| 7 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs ---|||----||-||||-||-|||--||||||||||||||||-|-|--|||||--||--|--|--- 7 [R T K L] COG0515 Serine/threonine protein kinase |||||||||||||||-||||||||-|||||||||||||----|||||-|||||||||||||||||| 7 [R] COG0517 FOG: CBS domain |||||||||||-|||-----|--|--||||||----------|||||-||||||||||||||||-- 7 [E] COG0560 Phosphoserine phosphatase -------------||---||-|----|||-----|-||----|||||-||-|||||---||||||| 7 [H C] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases -------------|||||||||--||----||||||||----|||||||||||||||||||||||| 7 [O] COG0760 Parvulin-like peptidyl-prolyl isomerase -------------|||-----|--------------------|||||-||||-|||||||||||-- 7 [R] COG0790 FOG: TPR repeat, SEL1 subfamily |-||||----|||---|-||||--|-|||-|---||||----|||||-||||||||||||||||-- 7 [R] COG0824 Predicted thioesterase ---|---------||-----||----|||-----|-||----||||||||--||||---|||||-- 7 [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 -||-||--||||-----|||||||--|---|--||-||----||||---||||--|---|||||-- 7 [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component ------------------|--|------------|||-----|||||-||||||||--|||||--- 7 [S] COG1289 Predicted membrane protein ----||--|-|--|||-||||-||--|---||||||||||--||||||||||||||||-||||||| 7 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes --|---||--|-|-----||-|----||||||||||||----|||||--|--|--|---||||||| 7 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins -------------------|-|----|||-||||||||||--|||||-||-----|---|||||-- 7 [K] COG2188 Transcriptional regulators -------------||---||----------------------|||||-||||----------|--- 7 [T] COG2198 FOG: HPt domain ------------------|--|--------------------|||||--|--|--|---||-|--| 7 [N U] COG3121 P pilus assembly protein, chaperone PapD --------------------------|-------|--|----------||---|||---|---|-- 7 [S] COG3182 Uncharacterized iron-regulated membrane protein --||----|-|-|----|||||--|||---||||||-||||||||||-||||-|||--||||||-- 7 [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components -------------------------------------------||----|-----|---|||||-- 7 [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain -|-----------||-|---||-|--|||||---|-||----||||||||||||||||||||||-- 6 [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase |-||||--|-|||||||-||-|-----||--|--||||----|||||-||-||--||-||||||-- 6 [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases --||---------||---||||----|||-|----|||----|||-|-||-|---|---|||||-- 6 [R] COG0384 Predicted epimerase, PhzC/PhzF homolog |||||||||||||||-||||-|----|---|--|---|----|||||--||||--|||||||||-- 6 [F R] COG0402 Cytosine deaminase and related metal-dependent hydrolases |||||||||||||||-|||||||||-||||||||||||----|||||-|||||||||||||||||| 6 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase |||||||||--|-|||||||||||||----||||||||----|||||-||-||||||||||||||| 6 [R] COG0457 FOG: TPR repeat |||-||--|--|-||||-||||--|-||||||||||||||||||||||||||||||||-||||||| 6 [L K J] COG0513 Superfamily II DNA and RNA helicases |-||||--|-||-||||-||||---|||||||||||||----|||||||||||||||||||-|||| 6 [P] COG0607 Rhodanese-related sulfurtransferase ---|||----|||||-||||||---|||||-|--||||----|||||-||--|--||--||-||-- 6 [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) |||||||||||||-||||||||--|||||-||||||||----||||||||--|||||||||||||| 6 [M] COG0668 Small-conductance mechanosensitive channel --||--|||--------|||----||----|----|||----|||||-||--|--||||||-||-- 6 [N T] COG0835 Chemotaxis signal transduction protein --|||||||--||||--|-|-|-----||-||||||||--|-|||||-|||-||||---||-||-- 6 [E R] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases --------------------------|||||||-||||----|||||--|---------|-|---- 6 [E] COG1113 Gamma-aminobutyrate permease and related permeases --||--||--||-|||||||||||--|||||||||||||||||||||||||||||||||||||||| 6 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components ---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||--||||||-- 6 [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II ---|||--|-|||-------||-----||||---|-||----|||||-||-----|---||||||| 6 [I] COG1250 3-hydroxyacyl-CoA dehydrogenase ---|------------||--||----|||||||-||||----||||||||||||||---||||||| 6 [K] COG1278 Cold shock proteins --||--------------|-||----|||-||-|-||-----|||||-||-|-|||---||-||-- 6 [S] COG1359 Uncharacterized conserved protein --||---------------|-|-----|||||---|||----|||||-||---||---||||||-- 6 [P] COG2076 Membrane transporters of cations and cationic drugs |-|-||----|||---|-||-|-----||-||---|||----|||||-||||-|||-|-|||||-- 6 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases --|----------------------|-----||--||-----|||||--|-----|---||||--- 6 [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components -------------||------------|||------------||||--||-----|------|--- 6 [Q] COG2175 Probable taurine catabolism dioxygenase ||-|-----|---------|-|-----|||----|-------||||---|-----|--||||||-- 6 [E] COG2303 Choline dehydrogenase and related flavoproteins ------------------|||----------------------|||---|||||||--|----|-- 6 [U] COG3210 Large exoproteins involved in heme utilization or adhesion --|--------|-------||-----||||--||---|-------|---|---||----||-||-- 6 [L] COG3547 Transposase and inactivated derivatives -----------------|||------|||-------------||||---|-----|---|||||-- 6 [P R] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit --||||-|--|||||-||||||----||||||||||||----||||||||||||||||||||||-- 5 [E] COG0031 Cysteine synthase ||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 5 [E H] COG0147 Anthranilate/para-aminobenzoate synthases component I ||||----|||||||-||||||||||||||||||||||||||---|---|---||||||||||||| 5 [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases |||||||||||||||---||-|----||||----||||----|||||-||-|-|||--||||||-- 5 [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) ||-||||||||||---|-||-|----|||-------||----|||||-||||---|||||||||-- 5 [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing -------------||-||||||||--||||||||||||----|||||||||||||||||||||||| 5 [I Q] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase ----------------|-||||||---||-||||||||----|||||-|||||||||||||||||| 5 [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III -------------|||--||||||||||||||||||||-|--|||||||||||||||||||||||| 5 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains |||||||||||||||||-||||----|||||-||-|||----||||||||||||||||||||||-- 5 [O] COG0501 Zn-dependent protease with chaperone function ---|||----|||||---||-|||--||||-|||||||-|||||||||||||||||---||||||| 5 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes |||||||||-|||||||-||||||-||||||||||||||||||||||||||||||||||||||||| 5 [F G R] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases |-||--|||----|--|-||-|--|||||-|||||||||---|||||-||||||||||||||||-- 5 [R] COG0546 Predicted phosphatases |-|||||||--||||---|-|--|--|------||-||----|||||-||||-||||||||||-|| 5 [E R] COG0591 Na+/proline symporter -|--|||||||||||-||--||-|--||||||||||||----|||||||||||||||||||||||| 5 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases -------------||||||||||||-|||||||-||||----|||||-||||||||--||||||-- 5 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases -||||||||||||||-|-||||--||-||-|--|||||-||||||||-||-||--|--||||||-- 5 [R] COG0693 Putative intracellular protease/amidase |||||||||||||---||||-|---||||||---||||----|||||-||--|--|---|||||-- 5 [R] COG0714 MoxR-like ATPases --|||||||-|||---||||||||--|||||||-||||----|||||-||||---||||||||--- 5 [E] COG0747 ABC-type dipeptide transport system, periplasmic component ----||----------||||||||||-||||||||||||||||||||||||||||||||||||||| 5 [L] COG0776 Bacterial nucleoid DNA-binding protein ------------------||-|||--||||||---|||----|||||-||||||||||||||||-- 5 [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins) |-|------|------|-||||||------------------|||||-|||||||||||||||||| 5 [U] COG0811 Biopolymer transport proteins |-||||||||||||||-|||-|----||||||||||||----|||||-||-||--|||-|||||-- 5 [V] COG0842 ABC-type multidrug transport system, permease component ------------------||-|----|||-|---||||----|||||||||||||||||||||||| 5 [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance |||---|||||||---|-||-|----||||||-|-|||-------|--||-----|---|||||-| 5 [F] COG1051 ADP-ribose pyrophosphatase --||---||---||||-|-|||||--|||-|||--|||----|||||-||-||--|---|||||-- 5 [R] COG1073 Hydrolases of the alpha/beta superfamily |-||||||||||||||-|||-|---||||||||||||||||-|||||-||-|||||||-|||||-- 5 [V] COG1131 ABC-type multidrug transport system, ATPase component ||||----|||||---|||||||||||||-|||||||||||||||||||||||||||||||||||| 5 [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component ---|----|-|-|----|-|||--||----||||||--|||||||||-||||-|||---|||||-- 5 [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I ||||||--|||||||-||||||||--||||-|||||||-|||||||||||||||||---||||||| 5 [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes |-|---||||||----||||-|-----||||----|||-----------||||--|---||-||-- 5 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases ----------------|---|-||------------------|||||-||--|--|--|---||-- 5 [N U] COG1450 Type II secretory pathway, component PulD ----------|||---|----|--|--||-------||----|||----|-----|---||-||-- 5 [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs ---|||----|||--------|||--|-------||||----||||||||||-|||||||||||-- 5 [I] COG1607 Acyl-CoA hydrolase ----------------|-----||||----|-----||----||||||||||||||--|||||||| 5 [T] COG1734 DnaK suppressor protein -----|--|-||---------|-----||-------------|||-|--|-----|---|||||-- 5 [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase ----------|||--------|--||-||-------||----|||----|-----|---||-||-- 5 [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs |-||----|-----|-||||-|-----||||---|-||----|||---||-----|---|||||-- 5 [T] COG2203 FOG: GAF domain -------|------|--|--||----|---||||||||----|||||-||||-|||---|||---- 5 [F] COG2233 Xanthine/uracil permeases --|-----------|-----|---------|----||||---|||||-||||-||||||-|-||-- 5 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) ----------------||||||||------||||||||----|||||-||||||||--|---||-- 5 [N U] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB ------------------|||----------------------|||---|||||||--|----|-- 5 [U] COG2831 Hemolysin activation/secretion protein ------------------------------------------|||||-||-----|---|--|--- 5 [S] COG3157 Hemolysin-coregulated protein (uncharacterized) -----------------|-|--------------------------|--|---------||-|--- 5 [R] COG3450 Predicted enzyme of the cupin superfamily ------------------------------------------|||||--|--|------------- 5 [N U] COG3539 P pilus assembly protein, pilin FimA ||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||-- 4 [F] COG0015 Adenylosuccinate lyase ||||||-|||---|||--||-|----|||--|-||||-----|||||-||-||------|--|--- 4 [P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters |||||||||||||||-||||||----||||||--||||----||||||||||||||--||||||-- 4 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase -|||--|||-|||-----||-|---------------|--||||||||||||||||---|||||-- 4 [H J] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 4 [P] COG0226 ABC-type phosphate transport system, periplasmic component |||-|||||||||---||||-|-----||-|------|----||||||||||||||---|||||-- 4 [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs |||||||||||||---|||||-||--||||||||||||----|||||||||||||||||||||||| 4 [E M] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase |||||||||||-||||----------||||||---|||----|||||-||--|-------|-|--- 4 [E] COG0367 Asparagine synthase (glutamine-hydrolyzing) ---|---------||---||-|----|||--|||||||--|||||||-||-|-|||---||-||-- 4 [R] COG0431 Predicted flavoprotein |||-----|--|-||-|-||-||||--||-||||||||----|||||-||||||||||||||||-- 4 [I] COG0439 Biotin carboxylase |||-|||||-|||||||||||||||--|||-||-||||----||||||||-||--||||||||||| 4 [O] COG0450 Peroxiredoxin ||||||||||||||||||||||----|||||||||||||---|||||-||||||||--||||||-- 4 [R] COG0456 Acetyltransferases |||---|||--|-||-|||||||||-||||||||||||----|||||-||||||||||||||||-- 4 [I] COG0511 Biotin carboxyl carrier protein ||||||-||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 4 [E H] COG0512 Anthranilate/para-aminobenzoate synthases component II |||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||-- 4 [F] COG0518 GMP synthase - Glutamine amidotransferase domain |-||--||-|-||-|--||||||||||||||||||||||||||||||-|||||--|||||||||-- 4 [E] COG0520 Selenocysteine lyase --|----------||-|-||||----|||-----|-||----|||||-||--||||||-|||||-- 4 [R] COG0523 Putative GTPases (G3E family) |||-||||||-|-||-||--|---|-|||-||-|-|||----|||||-||---|||---|----|| 4 [H C] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases -------------||---||-||||-|---------------||||||||||||||-------|-- 4 [O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 -------------||||||||||||||||||||||||||||||||||||||||||||||||||||| 4 [J] COG0564 Pseudouridylate synthases, 23S RNA-specific ||||----||||-----||||||||-|||-||||||||----|||||-||-|-|||--||||||-- 4 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component ----|--||---|----||||-----|||-|---|--|-||||||-|-||--||||||||||||-- 4 [R] COG0579 Predicted dehydrogenase ---|||-|--|-||||-|-|||--|-||||||||||||-||||||||-||||---|---|||||-- 4 [C] COG0584 Glycerophosphoryl diester phosphodiesterase ----||-----|------||-|--||||||||--||||----|||||||||||||||||--|||-- 4 [S] COG0586 Uncharacterized membrane-associated protein --|-|||---||-||--|||-|||--|||||||-||||-|--|||||-||||||||---|||||-- 4 [R] COG0637 Predicted phosphatase/phosphohexomutase |||||||||||||---||||||----|||||||-||||----|||||-||-|||||--||||||-- 4 [K] COG0640 Predicted transcriptional regulators --||--|||--------|||-|--||----|----|||----|||||-||--|--||||||-||-- 4 [N T] COG0643 Chemotaxis protein histidine kinase and related kinases --|----------||||-||--||--||||-|---|||----|||-|-||-|---|||-||-|--- 4 [P] COG0659 Sulfate permease and related transporters (MFS superfamily) |||---||||------|||||------||-------||----|||||-||--||||||-|||||-- 4 [G] COG0662 Mannose-6-phosphate isomerase ||||--||-|-|-||||-||||--|-||||||||||||----|||||-|||||--|||-||||||| 4 [I] COG0671 Membrane-associated phospholipid phosphatase -|-|----|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 4 [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component |||||--||||||---||||||----||||||||||||----|||||-||||||||||||||||-- 4 [C] COG0778 Nitroreductase ----------------|-||||||------------------|||||-|||||||||||||||||| 4 [U] COG0848 Biopolymer transport protein ----||||--|||||-|-|||---|-----|-|-||||----|||||-||||-|||||||||||-- 4 [C H R] COG1052 Lactate dehydrogenase and related dehydrogenases --|-----|-|-|----|||||||--|---||||||||----|||||-|||--||||||||||||| 4 [E] COG1126 ABC-type polar amino acid transport system, ATPase component ||||||-|||||-----|||-|----|||||-----------|||-|-||--|--||||||||||| 4 [C] COG1146 Ferredoxin ---|||----|||||--|||||----||||-|-|||||----|||||-||||||||--|||||||| 4 [E] COG1171 Threonine dehydratase ----------------||||||||||||||||||||||-|--|||||||||||||||||||||||| 4 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases ||||||||||-|||--||||-|----|||-||---|||||--|||||-|||-|||||||||||||| 4 [P] COG1226 Kef-type K+ transport systems, predicted NAD-binding component --||--|||--------|-|----||----|----|||----|||||-||-----|--|||-||-- 4 [N T] COG1352 Methylase of chemotaxis methyl-accepting proteins ----||||---|-|---------------------|||----|||-|--|-|-||----------- 4 [F] COG1457 Purine-cytosine permease and related proteins ----------------||||||||------||||||||----|||||-||||||||------||-- 4 [N U] COG1459 Type II secretory pathway, component PulF -----------------|--||----|||-||||||||-|--|||||-|||||--|---|||||-- 4 [K] COG1609 Transcriptional regulators -----------------||-|---|-|---------||----|--||-||||---|---||-||-- 4 [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component -----------------|------|-----------------------||--------|------- 4 [T] COG1639 Predicted signal transduction protein ||||||--|--||-----||||----|||-||--||||----|||||-||-||--|--|||-||-- 4 [K] COG1733 Predicted transcriptional regulators --|-||----|-------||------|||-|-----------|||||-||-|---|---|||||-- 4 [R] COG1741 Pirin-related protein --|----------------|||----||||-||||||------||-|--||-||||---|||||-| 4 [I] COG1835 Predicted acyltransferases --||------|-|-----|||-----|-----|||--|-----||||-||||||||--|||||--- 4 [P] COG1840 ABC-type Fe3+ transport system, periplasmic component ---|----|--|-||-----||----||||----|-|-----|--||-||-----|---|||||-- 4 [I] COG2030 Acyl dehydratase -------------||---|--|----||||------||-----------|-----|---||-||-- 4 [P] COG2072 Predicted flavoprotein involved in K+ transport ---------------------|----|||||----|||----|||||-||||-|||---|||||-- 4 [K] COG2186 Transcriptional regulators --||--|||--------|-|----||----|-----||----|||||-||--|--|--|||-||-- 4 [N T] COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain |-||||-||-|||||-|||||||||-|||||||||||||---|||||-||||-|||||||||||-- 4 [P] COG2217 Cation transport ATPase ---------------------|----|||-|---||||----|||-|--||----|--||-|---- 4 [S] COG2258 Uncharacterized protein conserved in bacteria ---|-------|-||----|-|----||||----|-||----|||||-||||-|||---|||||-- 4 [S] COG2259 Predicted membrane protein ----||--|-|||-----||-|---------------------------|-----|-----|-|-- 4 [R] COG2366 Protein related to penicillin acylase ----------|-|------||-----||-|-||||||-----|||||-||||-|||---|||||-- 4 [S] COG2606 Uncharacterized conserved protein ---------------------------||-|-----------|||||-||---------------- 4 [K] COG2909 ATP-dependent transcriptional regulator --------------------------|||-------------|||||-||-|||||---|||||-- 4 [M] COG2951 Membrane-bound lytic murein transglycosylase B ------------------|-----------------------|||||-||-||-||---|||||-| 4 [C] COG3038 Cytochrome B561 ------------------|-----------------------|||||--|--|--|---|--|--| 4 [N U] COG3188 P pilus assembly protein, porin PapC -------------------|-------||||-----||-------|---|-----|---|--|--- 4 [Q] COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis ------------------------------------------------||---|||||||||||-- 4 [O] COG3278 Cbb3-type cytochrome oxidase, subunit 1 --------------|-------------------------------|--|-----|---|||||-- 4 [S] COG3791 Uncharacterized conserved protein ---------|--------------------------------------||---------------- 4 [O] COG4067 Uncharacterized protein conserved in archaea ---------------------------------------------|---|-----|---|--|--| 4 [S] COG5430 Uncharacterized secreted protein ||||||--|||||-|-|-||||||--|||||---||||----|||||-||-|||||||||||||-- 3 [H] COG0001 Glutamate-1-semialdehyde aminotransferase ||||||--|||||||-|-||||----|||||---||||----||||||||--||||---|||||-- 3 [H] COG0007 Uroporphyrinogen-III methylase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases |||||||||||||||---||||--------|-|-|-||----|||-|-||-|||||||-||||--- 3 [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family ---|||----||||||--||-|||---||--|||||||-|||-------|-----|---||||||| 3 [C] COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control ||||----||---|||||||||||||||||||||||||----|||||-|||||||||||||||||| 3 [J] COG0042 tRNA-dihydrouridine synthase |||||||||||||||-||||||----||||||||||||----|||-|--|--|--|||||||||-- 3 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases ||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||-- 3 [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [R] COG0073 EMAP domain |||---||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [L] COG0084 Mg-dependent DNase ||||---|-||--||--|||-|||--||||||||||||----|||-|-||-|-|||--||||||-| 3 [R] COG0110 Acetyltransferase (isoleucine patch superfamily) |||||||||||||||-||||-|----||||||--||||----|||||-|||||--|||||||||-- 3 [H E] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases ||||||||||||||||||||-|||||||||||||||||-||||||||||||||||||||||||||| 3 [E] COG0112 Glycine/serine hydroxymethyltransferase |||--|||||||-||-||||-|----|||||--|||||----||||||||||||||--||||||-- 3 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases ||||--|||||||||||-||-|------------|-||----------||---|||---|||||-- 3 [B Q] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein --------|-||-||-|-||-|----|||-|-----||----||||||||--||||---|||||-- 3 [P] COG0155 Sulfite reductase, beta subunit (hemoprotein) |-|||||||-|||||||||-|||||-||||||||||||-||||||||||||||||||||||||||| 3 [F] COG0209 Ribonucleotide reductase, alpha subunit |-||||-------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 3 [L] COG0210 Superfamily I DNA and RNA helicases ||||-||||||-|||-||-||------||||-||-|||-||-|||||-|||||--|||--|||||| 3 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases --|----------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 3 [I Q] COG0236 Acyl carrier protein ||||||--|||||---|-||||----||||-|----||----|||||-||||-||||||||||--- 3 [C] COG0247 Fe-S oxidoreductase -------------||---||-|-----|||------------|||||-|||-||||---|||||-- 3 [H] COG0259 Pyridoxamine-phosphate oxidase |--|------||-||---||-|----|||||-||--||----|||||-||||||||||||||||-- 3 [P] COG0288 Carbonic anhydrase ||||||||||||-|---|-|-|||--|||||---||||----||||||||||-||||||||-|--- 3 [P] COG0306 Phosphate/sulphate permeases --|----------||-|-||-|----||||----|-||----||||||||||||||---||||||| 3 [S] COG0316 Uncharacterized conserved protein ----------------||||||---||||||||||||||-|||||||-||||||||||||||||-| 3 [T K] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases -||-||--||-|------||----------|-----------|||-|-||||-|||||||||||-- 3 [C] COG0348 Polyferredoxin ||||||||||||||--||-||-|||-||||||-|||||-|--|||||-||||||||||||||||-| 3 [L] COG0350 Methylated DNA-protein cysteine methyltransferase --|----------|--|-||------|--|----|-||----|||||--|---|||---|||||-- 3 [R] COG0385 Predicted Na+-dependent transporter -------------|||--|-|-----|---|||||||||---|||||--|--||||-------|-- 3 [O] COG0386 Glutathione peroxidase ||||--||||------||||------|||||---|||-|||||||-|--|--|--|---||||--- 3 [S] COG0392 Predicted integral membrane protein ---|||||---||||-||||-|-----|||----||||----|||||--|--||||---|||||-- 3 [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) ----||----||||||--||||----|||-----|-||----|||-|-||--||||||-||-||-- 3 [E] COG0405 Gamma-glutamyltransferase -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 3 [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component --|-|------|-||-|-||-------|||------|-----|||||--|-----|---||-||-- 3 [Q] COG0412 Dienelactone hydrolase and related enzymes -|--|||||||||||-||---|----|---|--|--||----||||||-|--||||||----|--- 3 [E] COG0421 Spermidine synthase ||||||--||||----|||||-------------|-|-----||||||||||-|||--||||||-- 3 [O] COG0425 Predicted redox protein, regulator of disulfide bond formation |-||||-------||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [O] COG0443 Molecular chaperone ||||||||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [O] COG0492 Thioredoxin reductase ---|||||---||||-||||-|||---|||--|-||||-|--|||||-||--||||---|||||-- 3 [E] COG0509 Glycine cleavage system H protein (lipoate-binding) |||||||||||||||--|||-|----||||||||||||----|||||-|||||--|---|||||-- 3 [G] COG0524 Sugar kinases, ribokinase family ||||--|||---|||-|||-||--|||||-|||||||||||||||||-||||||||||||||||-- 3 [V] COG0534 Na+-driven multidrug efflux pump ---|||-||--|||--||||||---|||||||||||||-||||||||-|||||--|---|||||-- 3 [C] COG0554 Glycerol kinase -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 3 [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 3 [K] COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) ---|||-----|-|||--|--|---|||||-|||||||----|||||-|||||--|---||||--- 3 [C] COG0578 Glycerol-3-phosphate dehydrogenase -||---|-|-||-||-||||||----|||||||||||-----|||||-|||||--|||||||||-| 3 [P] COG0598 Mg2+ and Co2+ transporters |||-||--||-|-||--||--|----|||--|---|||-------|---||-||||---|||||-- 3 [S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit -||||||||-|||----|||||----|---|||||||||---|||||-||||---|||||||||-- 3 [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component ----------|-|||-||||||---|-|||||||||||----|||||-|||||--||||||||||| 3 [R] COG0612 Predicted Zn-dependent peptidases ||||--|||-------||||||--|||||-||||||||----|||||||||||||||||||||||| 3 [R] COG0628 Predicted permease -----|-------||-|-||-|||--||||||||||||||||-------|--|--||--|--|--- 3 [T] COG0631 Serine/threonine protein phosphatase |||-||||-|-|----|-||-|----|||-|-----||----|||-|-||--||||--|||||||| 3 [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily ----||----|--|||--||||--|||---|-----------||||--||-|||||--|||-|||| 3 [R] COG0666 FOG: Ankyrin repeat |-||||||-|||-||-||||-|----|---||||||||----|||||-||-|---|||||||||-- 3 [R] COG0673 Predicted dehydrogenases and related proteins ||-------|---||-|||||-----|---||--||||----||||--||-||--|--|||||||| 3 [R] COG0679 Predicted permeases |-|-||--|--|-|||--||||--|||||-||||-||-----|||||-|||||||||||||||||| 3 [L] COG0708 Exonuclease III -|||--|||-||------||-|---------||---------|||||-||--|--||||-|-|--- 3 [R] COG0727 Predicted Fe-S-cluster oxidoreductase --|-||--|-|||---||||||---||||||||-||||--|||||||-||||||||||||||||-- 3 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 3 [O U] COG0740 Protease subunit of ATP-dependent Clp proteases -----------------|||||----||||||||||||----||||||||||||||||||||||-- 3 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) -------------||------|----|-------||||----|||||-||||-||||||||||--- 3 [P] COG0753 Catalase ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 3 [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2 -----------------|---||||||||||||||||||||||||||||||||||||||||||||| 3 [K] COG0782 Transcription elongation factor ----------------|--||---------------------|||||-||||||||||||||||-- 3 [M] COG0810 Periplasmic protein TonB, links inner and outer membranes -------------|||------||--|---------------|||||-||||-||-|||------- 3 [E] COG0814 Amino acid permeases |||------|-|----|--|||--------||||||||----|||||-||||-|||||||||---- 3 [O] COG0826 Collagenase and related proteases --||--|||-------||||-|--------|-----------|||||-||--|---||-|||||-| 3 [M] COG0836 Mannose-1-phosphate guanylyltransferase ----|---|----||||||--||||-|||-||||||||----|||||||||||||||||||||||| 3 [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases -|||---||--|----|-||------|||---|---||----|||||-||-||--|--|||||||| 3 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase ||||--||-|||-|||-|-|-|--|||||-||||||||----|||||-||-|-|||---|||||-- 3 [R] COG1011 Predicted hydrolase (HAD superfamily) ||-|||--|||||||-||||||||--||||||--||||----|||||-|||||||||||||||||| 3 [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit ---|||----||||||--||-|||---||--|||||||-|||-------|-----|---||||||| 3 [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit -|----||-|--|---||--||||-------||||||-----||||||||||||||---||||--- 3 [R] COG1092 Predicted SAM-dependent methyltransferases --|---||------------|||||-|-----|||-||----|||-|-||||-||-|||-||---- 3 [E] COG1115 Na+/alanine symporter |||-|||||||||----|||||--------|-----|-----|||||-|||||||||||||-|--- 3 [C] COG1145 Ferredoxin --|-------------||||||||||||||||||||||----|||||-|||||||||||||||||| 3 [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes -------------------|----------||--||||-||||||||--||----|---||-|--- 3 [I] COG1182 Acyl carrier protein phosphodiesterase ||-|-|||-|||----|-||-||||||||||----|||--|||||||-||--|||||||||||||| 3 [D] COG1192 ATPases involved in chromosome partitioning -----------------|||----------|----||-----|||||-||-----|---------- 3 [K T] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ||||||||||----|-|-|||-||||----||||||||----||||---|-----|---||||||| 3 [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I --|||||||--||----|||-|--||----|---|||||||--------|-----|----||---- 3 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component ----------------|-||||--|--||-||-|-|||----|||||--|||---|---|||---- 3 [S] COG1285 Uncharacterized membrane protein ---|--------------------|-|||-----||||----|||||-||||-||-----|----- 3 [M] COG1292 Choline-glycine betaine transporter --||--||----|---|--||||||||||-|---|-||----|||||-||--|--|--|||-|||| 3 [C] COG1301 Na+/H+-dicarboxylate symporters ----------------||--||----|---||||||||----|||||-||||-|||---||||--- 3 [K G] COG1349 Transcriptional regulators of sugar metabolism --||--------------||-|--|-|||-||---|||----|||||--|-|-------||-|||| 3 [S] COG1357 Uncharacterized low-complexity proteins ----------------||------||----|----|||----|||||-||-----|||||||||-- 3 [N] COG1360 Flagellar motor protein -----------------||||||||--||-|---||||----------||---------||--|-- 3 [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) |-|||||||--||||-||--|-----|---||-|||||----|||||-||-|---|---||||--- 3 [C] COG1454 Alcohol dehydrogenase, class IV --------------------||-||-|---||||||||----|||||-||||||||||||||||-- 3 [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen -------------||------|-----||-------------|||||-||--||||---||||||| 3 [R] COG1485 Predicted ATPase -----------------|||----|------|----||----|||----|-|---|-----|||-- 3 [R] COG1512 Beta-propeller domains of methanol dehydrogenase type ------||------------||----|--|----|-||----|||||-|||--|||--||------ 3 [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B -----------------|--|---|-|----------|----|--||-||||-------||--|-- 3 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component ||||||--|||||||-||--||----||||||||||||----||||||||||||||||||||||-- 3 [E] COG1605 Chorismate mutase --|-||||||||-|--||-|||||--||||-|--|-||----|||||-||-|||||--||||||-- 3 [R] COG1611 Predicted Rossmann fold nucleotide-binding protein ---|----|-|-----|-||-|||--||||----|||-----|||||-|||||||||||||||||| 3 [O] COG1651 Protein-disulfide isomerase --|||||||-|-|---||||-|---|-|||-----|||----------||-----|---|||||-- 3 [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) -----------------|--------|---||||||||-|--|||||-||||-|||---|||||-- 3 [K] COG1737 Transcriptional regulators -------------||||||-|---|--|||-|----||----|||-|-||--||||---||||||| 3 [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily ---|------||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 3 [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3 --------------------|||||||---||||||||||||||||||||||||||---|||||-- 3 [G] COG1925 Phosphotransferase system, HPr-related proteins ----------------||||||-----||-||-|||||----|||||-||||||||--|||||||| 3 [K] COG1959 Predicted transcriptional regulator ------||-----|------||----||||----|-||----|||||-|||--|||--||---|-- 3 [E] COG1984 Allophanate hydrolase subunit 2 ------||-----|------||----||||----|-||----|||-|-|||--|||--||---|-- 3 [E] COG2049 Allophanate hydrolase subunit 1 ----------------|---|---------------------|||||-|||||||-||-|||||-- 3 [I] COG2067 Long-chain fatty acid transport protein --------|----|--||-|||----|||-||||||||-----------|--||||||||||-|-- 3 [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase -||-|||||||||---|--|-||||-----------|-----||||||||-|||||--||||||-- 3 [U] COG2095 Multiple antibiotic transporter ---|---------||---||-|----|||||-----||-----------|--|--|--||||||-- 3 [Q] COG2124 Cytochrome P450 ------------------||-------|||------------|||||-||--||||---|||||-- 3 [P] COG2193 Bacterioferritin (cytochrome b1) ------------------------------------------|||||-|||||||-||||||--|| 3 [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase -----------------||||-|||--||-|---||||----------||----------|-|--- 3 [T K] COG2208 Serine phosphatase RsbU, regulator of sigma subunit ----------------|---------||||----|-||----|||-|--|-----|----||-|-- 3 [P] COG2223 Nitrate/nitrite transporter -------||----||--|-|||----||||||--||||----|||||-||||---|---|||||-- 3 [I] COG2267 Lysophospholipase ----------------------||-------||-|-|-----|||||-||||------|-----|| 3 [G] COG2271 Sugar phosphate permease --|---------------||-|----|||-------------------||-----|--||||||-- 3 [S] COG2326 Uncharacterized conserved protein ----||----|||------|------|||------|||----|||-|-||--||||----|-||-- 3 [G] COG2513 PEP phosphonomutase and related enzymes --|-----------------|-----|---|-|-|-||----|||||-||||-|||---------- 3 [G E] COG2610 H+/gluconate symporter and related permeases -----------|-||---||-------|||||||-|||----|||||-||-|-|||--||||||-- 3 [E] COG2755 Lysophospholipase L1 and related esterases ---------------------|----|---|--|-||-----|||-|--|-----|--|--|---- 3 [P] COG2807 Cyanate permease ---------------------|-----------------------|--||-|-||||||-|----- 3 [C] COG2863 Cytochrome c553 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 3 [J] COG2890 Methylase of polypeptide chain release factors -----|--------------||----|||--|||||-|----|||||-|||----|---|||||-- 3 [L] COG2963 Transposase and inactivated derivatives --------------------|---------------------|||||-||||||||---|||||-| 3 [V] COG3023 Negative regulator of beta-lactamase expression --------------------|-----|----------|----|--||-||||-------||--|-- 3 [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component --||---|------|------------||-------------|||||--|||-------|||||-- 3 [P] COG3119 Arylsulfatase A and related enzymes ----------||------|----------------|------|---|--|-----|---|-|||-- 3 [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol --------------------------||||-------------------|------||||||||-- 3 [E] COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ------------------|-----------------------|||-|--|---------------- 3 [S] COG3204 Uncharacterized protein conserved in bacteria --|---------------------------|----||-----|||||--|-----|------|--- 3 [M] COG3209 Rhs family protein ---|------|--------||-----|||--|--|--|----||||--||---------||-||-- 3 [P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component ------------------------------------------------||---|||-------|-- 3 [C] COG3245 Cytochrome c5 -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3455 Uncharacterized protein conserved in bacteria --------------------------|------------------|---|-----|---||||||| 3 [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3515 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3516 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3517 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3518 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3519 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3520 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3522 Uncharacterized protein conserved in bacteria -------------------------------------------||||-||-----|---|--|--- 3 [S] COG3523 Uncharacterized protein conserved in bacteria ---|------|--------||-----|----|--|--|-|||||||---|---------||-||-- 3 [P] COG3639 ABC-type phosphate/phosphonate transport system, permease component ------------------|------------------------------|-----|-------|-- 3 [M] COG3659 Carbohydrate-selective porin -------------------|-|-----||--------------|||--||--|--|---|||||-- 3 [R] COG3668 Plasmid stabilization system protein ---------------------------||--------------------|-----|-------|-- 3 [R] COG3687 Predicted metal-dependent hydrolase -----------------|||-----|-----------|-----------|--------|||||||| 3 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain --|----------------|-------------------------|--||-----|---|--|--- 3 [S] COG4104 Uncharacterized conserved protein ------------------------------------------|||||-||||-------||-|--- 3 [E] COG4160 ABC-type arginine/histidine transport system, permease component -----------------|--|-|||||||-||-||||-||--|||||-||||---|||-||||--- 3 [E] COG4166 ABC-type oligopeptide transport system, periplasmic component -|------|-|||----|||||----|------|---|----|||||--|-----|--|||||--- 3 [E] COG4177 ABC-type branched-chain amino acid transport system, permease component ------------------------------------------------||-----|---||-|--- 3 [T] COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system ------------------------------------------|||||-||||-------||-|--- 3 [E] COG4215 ABC-type arginine transport system, permease component -------------------------------------------------|-----|----|-|--- 3 [C] COG4313 Protein involved in meta-pathway of phenol degradation ------------------------------------------|||||--|-|---|---------- 3 [S] COG4575 Uncharacterized conserved protein ------------------------------------------|||||-||---------||-|--- 3 [E] COG4598 ABC-type histidine transport system, ATPase component ------------------------------------------|||||-||--------||------ 3 [P] COG4771 Outer membrane receptor for ferrienterochelin and colicins ------------------------------------------|||||--|---||----------- 3 [P] COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid ------------------------------------------|||||-|||||--|-------|-- 3 [U] COG4795 Type II secretory pathway, component PulJ ---|--|||--|-||--|--||----||||------||-----------|-----|---||||||| 3 [I] COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) ---|||--||-||----|||||----||||||--||||----|||||--|-----|---|||||-- 3 [M R] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily ------------------------------------------|||-|--|---------||||--- 3 [S] COG5457 Uncharacterized conserved small protein --------------------------|---------------|||----|-----|---------- 3 [Q] COG5517 Small subunit of phenylpropionate dioxygenase |||-||--||-|-||-||||-|----|||-||--|||||---|||||--|--||||---|||||-- 2 [P] COG0004 Ammonia permease |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 2 [E] COG0006 Xaa-Pro aminopeptidase ||||||||||||||||||||||||||||||||||||||||||||||||||||||||---||||||| 2 [J] COG0009 Putative translation factor (SUA5) |||-||--||---||-||||-|----||||||-|||||----||||||||||||||||||||||-- 2 [E] COG0019 Diaminopimelate decarboxylase ||||||||||||||||||||||||||||||-||||||||||||||||||||||||||||||||||| 2 [J] COG0024 Methionine aminopeptidase |||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-||| 2 [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases ---------|---||-|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0050 GTPases - translation elongation factors |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 2 [E] COG0069 Glutamate synthase domain 2 |||||||||||||||-||||-|---|||||||||||||--|-||||||||||||||--||||||-- 2 [E] COG0078 Ornithine carbamoyltransferase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 2 [E] COG0107 Imidazoleglycerol-phosphate synthase ---|||--|-|||||-|-||-|----||||----||||----||||||-|--|--|---||||||| 2 [O] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor) --||------|||||---|--|||--||||----||||----|||||-|||||||||||||||||| 2 [C] COG0114 Fumarase ||||----|||--||-||||||----||||||||||||----|||||-|||||||||||||||||| 2 [E H] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 2 [E] COG0118 Glutamine amidotransferase |||----||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 2 [E G] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase |||||-|||||||||-||||-|||--||||||-|||||----|||||||||||||||||||||||| 2 [E] COG0136 Aspartate-semialdehyde dehydrogenase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 2 [H] COG0142 Geranylgeranyl pyrophosphate synthase --||||||--|||||----|-|----|||||---|-||----|||||-|||----|---||||--- 2 [E] COG0160 4-aminobutyrate aminotransferase and related aminotransferases |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0162 Tyrosyl-tRNA synthetase |||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 2 [F] COG0167 Dihydroorotate dehydrogenase ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 2 [E] COG0169 Shikimate 5-dehydrogenase -||||-||-||||||---||||----|||-|-----||----||||||||--||||---|||||-- 2 [E H] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes --||||--|----||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit --||||--|----||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0223 Methionyl-tRNA formyltransferase ------------------|--|----||||-----|------|||||-||||---|---||||||| 2 [F] COG0232 dGTP triphosphohydrolase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0242 N-formylmethionyl-tRNA deformylase |||||||||||||||-----||----||||||||||||----|||||-|||-||||||||-|---- 2 [E J] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0254 Ribosomal protein L31 -------------||-||||-||||||||||||||||||||||||||||||||||||||-|||||| 2 [J] COG0257 Ribosomal protein L36 --|----------|||-|--||||--||||||||||||||||||||||||||||||---|||||-| 2 [H] COG0262 Dihydrofolate reductase |-||------||-||-||||||||||||||||||||||----|||||||||||||||||||||||| 2 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain --|||||||-|||||--|||-|----|||-|||-||||----|||||-||||||||--|||||||| 2 [C] COG0281 Malic enzyme --|--------|-|--|-||||||--|||----|--|-----|||||-||||---|---||-|--- 2 [G] COG0296 1,4-alpha-glucan branching enzyme --|----|---|-|||---||-----||||||||||||-----------|-|---|---||-||-- 2 [R] COG0300 Short-chain dehydrogenases of various substrate specificities ----------||-||-|-||||----||||||||-|||----|||||-|||||--||||||||||| 2 [H] COG0302 GTP cyclohydrolase I |||||||||||||---|-||-|----|||||---||||----|||||-||||---|||||||||-- 2 [H] COG0303 Molybdopterin biosynthesis enzyme -------------|||--|||---|||||||----|||----|||||||||||--||||-|-|-|| 2 [O] COG0326 Molecular chaperone, HSP90 family -------------||-||||||||--||||||||||||----|||||-|||||||||||||||||| 2 [I] COG0331 (acyl-carrier-protein) S-malonyltransferase --|||||||-|||||--|||||||--|---|--|||||----|||||--|||-|||||--||-|-- 2 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase ||||--||-|------|||||||||||||||---||||-|--|||||-|||||||||||||||||| 2 [U] COG0342 Preprotein translocase subunit SecD --|-|||||----||-|-||||----||||||-|||||----|||||-||||||||||||||||-- 2 [H] COG0352 Thiamine monophosphate synthase -------------|||||||-||||||||--|-||||-----||||||||||||||||-|||||-- 2 [G] COG0364 Glucose-6-phosphate 1-dehydrogenase --|-||----|--||--|||-|----|||-||||||||-|--|||||-||-----|---||-||-- 2 [G] COG0366 Glycosidases |-||||--|-|||||-||||-|----||||-|--||||----|||||-||-||||||||||||||| 2 [C] COG0372 Citrate synthase --||-------|-||---|||-----|||-|||||||||||||||||-||-|-|||---|||||-- 2 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair |-||----|----||-|-||-|----|||-||||||||----|||-|-||-|||||--||||||-- 2 [T] COG0394 Protein-tyrosine-phosphatase ---|||||--|||----|||-|--|-||||||||-|||-||||||||-||-||--|---||||--- 2 [G] COG0395 ABC-type sugar transport system, permease component ||-----|-||-----||||----|-|||-|--|--|-----|||||-||-|-||||||-||||-- 2 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis ---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||-- 2 [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain --|-||-----|-||-||||||----||||||||||||----|||||-||-||--|---|||||-- 2 [G] COG0406 Fructose-2,6-bisphosphatase -|------|-|||----|||||-----------|--------|||||--|-----|--|||||--- 2 [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component ---|--||--|||||-||||-|----|||||---||||----||||||||--||||||||||||-- 2 [H] COG0413 Ketopantoate hydroxymethyltransferase --|---||-----||-||||||||--|||||-----||----|||||-||-||||||||||||||| 2 [D] COG0424 Nucleotide-binding protein implicated in inhibition of septum formation ---|----|----||---|-|-----|---------------|||||--|---------|-|-|-- 2 [C] COG0427 Acetyl-CoA hydrolase --|----------||-||--||||||----|-----|||||||||||||||||||||||||||||| 2 [O] COG0466 ATP-dependent Lon protease, bacterial type -|||||||--||||||-|||||||-|||||||||||||||||||||||||||||||--||||||-- 2 [G] COG0469 Pyruvate kinase ||----||-|||-||-||||||||||||||||||||||----|||||||||||||||||||||-|| 2 [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase |||-|--------||||-|||-----||||||||-||||||||||||--|----------|||--- 2 [P] COG0474 Cation transport ATPase |||-|||||-|||||-|-||-|---|-|||||--||||----|||||-|||-|||||||||||||| 2 [P] COG0475 Kef-type K+ transport systems, membrane components |-|||||||-|||||||-||||----|||||--|||||----|||||-||||||||||||||||-- 2 [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [J] COG0480 Translation elongation factors (GTPases) --|-||||--|-|||||||--|--|-||||||--||||----|||||-||--|--|--|||||||| 2 [E R] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases ||||--||-||||||--|||||--|||||-||||||||||||||||||||||-||||||||||--- 2 [F] COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins ||||||||||||||||||||-|||||||||||||||||||--|||||||||||||||||||||||| 2 [F] COG0504 CTP synthase (UTP-ammonia lyase) ||-|||||-|--|||-||||||-|-|||||||||||||----||||||||||||||||||||||-- 2 [F] COG0516 IMP dehydrogenase/GMP reductase |||||||||||||---|--|-|----|||||---||||----|||||-||||---|||||||||-- 2 [H] COG0521 Molybdopterin biosynthesis enzymes -------||---|||-|-|--|-----||-|-----||----||||||||--|--|--|-||||-- 2 [P] COG0529 Adenylylsulfate kinase and related kinases |||||||||||||---||||-|-----||-||--|-||-----------|-----|----|-|--- 2 [R] COG0535 Predicted Fe-S oxidoreductases ||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 2 [E] COG0547 Anthranilate phosphoribosyltransferase |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-| 2 [E] COG0548 Acetylglutamate kinase --||-||||--|||||-|||||||--|||-||||-|||--|||||||-|||||-------|----- 2 [K L] COG0553 Superfamily II DNA/RNA helicases, SNF2 family |-|||||||-|||||||||||-|||||||||||||||||||||||||-|||||||||||||||||| 2 [I] COG0558 Phosphatidylglycerophosphate synthase --||--|||----||||||||||||||||||||||||||||||||||||||||||||||||||||| 2 [F] COG0563 Adenylate kinase and related kinases |-------|--|-|||-||-||---|----||||||||-|||||||||-||||--|---|||||-- 2 [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0587 DNA polymerase III, alpha subunit --|----------||||-||-|||--||||||-|||||----||||||||||||||---||||||| 2 [F J] COG0590 Cytosine/adenosine deaminases ----------------||||-||||||||||||||||||||||||||||||||||||||||||||| 2 [L] COG0593 ATPase involved in DNA replication initiation ||||||||||||----|-|||---------||||||||----|||||-|||||||||||||||||| 2 [O] COG0602 Organic radical activating enzymes |-||||----|||||||-||-|||-|||||||||||||----|||||||||||||||||||||||| 2 [P] COG0605 Superoxide dismutase -||||||||-|||----|||||----||||||||||||----|||||-||||---|||||||||-- 2 [P] COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component |||||||||-|-|---|||||||||-||||-----|||----|||||||||||||||||||||||| 2 [O U] COG0616 Periplasmic serine proteases (ClpP class) -------------|||||||||||||||||||||||||----|||||||||||||||||||||||| 2 [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase |||||||||||||---||||||-||-|||||---|-||----|||||||||||||||||||||||| 2 [J] COG0621 2-methylthioadenine synthetase --||||||--|||||--|--||----||||||||||||----|||||-||||||||||||||||-- 2 [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases ----------------|||||||||||||-|||||||||---|||||||||||||||||||||||| 2 [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases -|||||||||||||||-|||||--------||-|-|||----||||||||||||||--|||-||-- 2 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases |-||---------|||--||||--|-||||||||||||----|||||-||||||||||||||||-- 2 [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 2 [U] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase) ---|||||--||||||-||-------||||||||||||----|||||--|-----|---|||||-- 2 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase --|--|--|--|-||--|||-|--|-|||||||-||-|----|||||-||--|--|---||-||-- 2 [I] COG0657 Esterase/lipase -------------|------------|---------------|||||-|||||------------- 2 [G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase ||||||||||||||||||||||||||||||||||||||-|--|||||||||||||||||||||||| 2 [U] COG0681 Signal peptidase I |-||----|----|||-|||-|----|||||||||||-----|||||-||||||||---||||||| 2 [O] COG0695 Glutaredoxin and related proteins ---|---------||-|-||-|----|----|--||||----|||||-|||-|--|---|||||-- 2 [M G] COG0702 Predicted nucleoside-diphosphate-sugar epimerases -------------||----|-|----|----|-|--------||||||||||||||------||-- 2 [E] COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase --|--|-|-|---|||-|||||||---|||||||||||----|||||-||--|--|||-|||||-- 2 [G] COG0726 Predicted xylanase/chitin deacetylase ----------------|||||||||||||||-----------|||||||||||||||||||||||| 2 [R] COG0728 Uncharacterized membrane protein, putative virulence factor ----------------|---|---------------------|||||-||||||||---|||||-- 2 [M] COG0729 Outer membrane protein ----------------||||----||----||||-|||----|||||||||||||||||||||||| 2 [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) -----------------|||||----|||||-----||-------|-||||||--|||||||||-- 2 [E] COG0757 3-dehydroquinate dehydratase II ----------------||||||||------||||||||----|||||||||||||||||||||||| 2 [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases ----------------|-||-------|||------------|||||-|||||||||||||||||| 2 [Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 2 [D] COG0772 Bacterial cell division membrane protein ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 2 [M] COG0773 UDP-N-acetylmuramate-alanine ligase ----------------|-||||||--|||-||||||||----|||||-||||||||||||||||-- 2 [I] COG0777 Acetyl-CoA carboxylase beta subunit --------------|-|-||||--||||||||||||||----|||||-|||||||||||||||||| 2 [M] COG0787 Alanine racemase ---|------------|-||-|----|||-------||----|||-|-|||||--|||||||-|-- 2 [F] COG0788 Formyltetrahydrofolate hydrolase ----||----||----||||||||||----|---||||----|||||-|||||||||||||||||| 2 [M] COG0793 Periplasmic protease -----------------|||||||||----------------|||||-|||||||||||||||||| 2 [R] COG0795 Predicted permeases ----------------|-||----||----|-----------|||||-|||||||||||||||||| 2 [M] COG0797 Lipoproteins -----------------|||----|-----||||--||----|||||-||||||||||-|||||-- 2 [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase -------------||-||||||||--||||||||||||----|||||-||||||||||||||||-| 2 [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase |-||--|||-|-|---|||||||||-||||||||||||-------||--|||-||---|||-|-|| 2 [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin ----||--|----||-||||||||--||||||-||-||----||||||||||||||||||||||-- 2 [H] COG0807 GTP cyclohydrolase II ----------------||||||--|-|||-|||||||||---||||||||||||||||||||||-- 2 [R] COG0820 Predicted Fe-S-cluster redox enzyme --|-----|---------||--||------------------|||||-|||||--||||||||||| 2 [U] COG0823 Periplasmic component of the Tol biopolymer transport system -------------||---------------||--|||-----|||||--|-----|||-------- 2 [E] COG0833 Amino acid transporters --||||--|-|||---|-||-|-----||-------------||||||-|--|||||||||||||| 2 [C] COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A) ---|------||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 2 [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 ------||||||||||||--||----|||||-|-||||-|--|||||-||-|---||||----|-- 2 [K] COG0846 NAD-dependent protein deacetylases, SIR2 family ----------------|-|||---------------------|||||-|||||||||||---||-- 2 [M] COG0859 ADP-heptose:LPS heptosyltransferase ----------------|-|||||||||||||---||||----||||||||||||||||||||||-- 2 [M] COG0860 N-acetylmuramoyl-L-alanine amidase ---|||||---||||-||||-|-----|||----||||----|||||--|--|-||---|||||-- 2 [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain --||||-||-|||---|-||-|----|||-----||||----||||||||--|||||||||||||| 2 [C P] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit |||-|||||||||----|||||-----||-||-----|----|||-|-||------------|--- 2 [C] COG1032 Fe-S oxidoreductase -|||||||||||-------|----------------------|||||-||---||-----|-|--- 2 [C] COG1042 Acyl-CoA synthetase (NDP forming) --||----------|--|||------||||||||||||----||||||||||-|||||||||||-- 2 [E] COG1045 Serine acetyltransferase |||||||||||||-------||--|-----------------|||||-|||||||||||------- 2 [O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 --||||----|||||-|----|----||||||--|||-----|||||-||--||||---||||||| 2 [C] COG1048 Aconitase A -------------||-|||||---||||||||||||||||||||||||||--||||||||||||-- 2 [H] COG1057 Nicotinic acid mononucleotide adenylyltransferase --|-||----|||||---||------||||-||||-||----|||-|--|--|||||||||||--- 2 [R] COG1064 Zn-dependent alcohol dehydrogenases --------|---|||--|||----|||||-||-|||||----|||||--|||---|---||||--- 2 [G] COG1070 Sugar (pentulose and hexulose) kinases --------|----||---||-|----|---|---|-||-|--------||--|--|---------- 2 [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold -------------|||--|-----------------------||||||||||-|||--|||||||| 2 [O] COG1076 DnaJ-domain-containing proteins 1 --------------------||||-||---||||||||-|||||||||||||||||------||-- 2 [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) |||---||||-|-----|||------|||||-|-||||----|||||--|-----|---|||||-- 2 [G] COG1082 Sugar phosphate isomerases/epimerases |-||-||||--||---|-||||----|||||||---||----|---|--|--||||---||-|||| 2 [M] COG1091 dTDP-4-dehydrorhamnose reductase --|-----|----||||||||||||-||||||||||||----||||||||||-||||||||||||| 2 [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes |-||--|||-|-|---|||||||||-||-|||||||||----||||||||||-||---|||||-|| 2 [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components |||||||||||||||||||||||||||||||||||||||-|||||||||||||||||||||||||| 2 [G] COG1109 Phosphomannomutase |||||-||||-|-||||||-|------||||---|---|||||||-|--|--|---|--------| 2 [L] COG1112 Superfamily I DNA and RNA helicases and helicase subunits --------------------|-|||-|---|-|||-|-----|||||-||||-------------- 2 [E] COG1114 Branched-chain amino acid permeases -||||||||--||----|||||----|---|-|||||||-|||||||-||||---|||||||||-- 2 [P H] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components |-||--|||-|||---|||||||||-|--|||||||||----||||||||||-||---|||||-|| 2 [P] COG1121 ABC-type Mn/Zn transport systems, ATPase component ----------------|-||-------|||------------|||||-|||||||||||||||||| 2 [Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component --|-----|-------|-||------|||||||-||||--------|-||-||||---|-|||||| 2 [G M] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component ------------------||||-||-|---||||||||----|||||-||||||||||||||||-- 2 [P] COG1135 ABC-type metal ion transport system, ATPase component ----------------||----||||----|----|||----||||||||-----|||||||||-- 2 [N U] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase --------|----------|||-----||-|||||||-----|||||--|-----|||-||||--- 2 [E] COG1174 ABC-type proline/glycine betaine transport systems, permease component ---|||||--|||----|||-|--|-||||||||||||-||||||||-||-||--|---||||--- 2 [G] COG1175 ABC-type sugar transport systems, permease components ---|--||--|-|-----||||--|-|------|---|----|||||-||||-|||--|||||--- 2 [P] COG1178 ABC-type Fe3+ transport system, permease component ||||----||---||-----|-||-|-||||-----||-----------|--|||||||||||-|| 2 [I] COG1183 Phosphatidylserine synthase -------------||-|||||||||||||||||-||||----|||||||||||||||||||||||| 2 [J] COG1186 Protein chain release factor B ||||||||--|||||||-|||-----|||-||||||||----|||||-||||||||-------|-- 2 [K L] COG1199 Rad3-related DNA helicases |-|-||||||||-||||-||------|---|||-||||----|||||--|-----|---|||||-| 2 [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis --|---|---||-|||||-|-|----|--||||||||-----|||||--|-|||||--||||||-- 2 [P] COG1230 Co/Zn/Cd efflux system component -||------|------|-------------------------|||||-||||||||--|||||||| 2 [S] COG1238 Predicted membrane protein --|-------------|----------||-|---|-||----|||||--|-----|---||-||-- 2 [C] COG1251 NAD(P)H-nitrite reductase ---|-------|-||---||-|----||||-|--||||----|||||-|||----|---||||--- 2 [C] COG1252 NADH dehydrogenase, FAD-containing subunit --||---------||-|||||||||||||-|||||||-|||||||||||||||||||||||||||| 2 [R] COG1253 Hemolysins and related proteins containing CBS domains --|-----------|---||--||---||-------||----------||-|||||---|||||-- 2 [S] COG1262 Uncharacterized conserved protein |-||--||--|-|---|||||||||||||-||||||||-----||||-||-----|------||-- 2 [R] COG1266 Predicted metal-dependent membrane protease --------------------|---|-|-----||||||-|--|||-|-||--------|||||--- 2 [P] COG1283 Na+/phosphate symporter ----------------||------||----|----|||----|||||-||-----|||||||||-- 2 [N] COG1291 Flagellar motor component --|-------------|-||||||--||||||||||||-|--|||||-|||||||||||||||||| 2 [S] COG1295 Predicted membrane protein |||||||||||||||---||-|--||||||-||||||-----|||||-||||-||----||||||| 2 [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases |-|||||||||||||||-||-|-----||--------------||||--|-----|---------- 2 [R] COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily -----------------|----||||----|-----||----||||||||-----||||---|--- 2 [N U] COG1317 Flagellar biosynthesis/type III secretory pathway protein ----------------||------||----|----|||----|||||-||-----|||||||||-- 2 [N] COG1344 Flagellin and related hook-associated proteins --|---||------------||--------||--|-||----|||||-||||-|||-----|---- 2 [M] COG1346 Putative effector of murein hydrolase ||||--|||||-|----|-|||--------||||||||||--|||-|--|----------|----- 2 [G] COG1363 Cellulase M and related proteins -----------------|------------|||-|||-----|||-|-||||-||-|||||-|--- 2 [M] COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily -----------------|||------|||||-----||----|||-|-||---|||---||||--- 2 [S] COG1376 Uncharacterized protein conserved in bacteria --|---||------------||--------||--|-||----|||||-||||-|||-----|---- 2 [R] COG1380 Putative effector of murein hydrolase LrgA ----------------||||||--||||||||||||||||--|||||||||||||||||||||||| 2 [S] COG1385 Uncharacterized protein conserved in bacteria -------------------|||----|--||||||||||-|||||||-||||||||--||||||-- 2 [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family --||----|-|-|||||-||||----|||||-||--||||------|-||--||||--|||-|--- 2 [O] COG1404 Subtilisin-like serine proteases ||||-----|--------||-------||--------------------|-----|---||||--- 2 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases ----------------||||-|----|---||--||------|||||-||||||||---||||||| 2 [S] COG1434 Uncharacterized conserved protein -------------||-----|-||------------------|||||-||||||||----|-|--- 2 [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase ----------------|-||-------|||------------|||||-|||||||||||||||||| 2 [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component -----------|--|--|||-|---|||||||---|||----|||||-||||||||---||||||| 2 [G] COG1472 Beta-glucosidase-related glycosidases --||||||---|-----|||||----|||-||-|||||----|||----|||---|--||||||-- 2 [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase ||-|--|||-|||---|--|-|||||||||||||||||----|||||-||--|||||||||||||| 2 [K] COG1475 Predicted transcriptional regulators --|||||||||||||-||||||--|||||-||||||||||||||||||||-|||||--|||||--- 2 [H] COG1488 Nicotinic acid phosphoribosyltransferase ---------------------|||------------||----|||||-|||||||||||||||||| 2 [O] COG1495 Disulfide bond formation protein DsbB ----------------|-||||||-||||||---|-||----|||||-||||||||--|||||||| 2 [S] COG1496 Uncharacterized conserved protein ---|--||-||||---|||||-||--|||||----|-|----||||||||||||||---||||||| 2 [J] COG1530 Ribonucleases G and E -----------------|------------------|-----|||-|-||-----------|---- 2 [Q] COG1535 Isochorismate hydrolase -------------||---||||||--||||||||||||----|||||-||||||||||||||||-- 2 [H] COG1539 Dihydroneopterin aldolase ---|------------||||||----|||||-||-||||||||||||-||--||||||||||||-- 2 [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced) --------------------|-||--||||------------|||||-|||||||||||||||||| 2 [M] COG1560 Lauroyl/myristoyl acyltransferase --||||||----|---||--||-----||------|||--------|--|-----|---|||||-- 2 [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold ----------------||------||----|-----||----|||||-||-----||||------- 2 [N] COG1580 Flagellar basal body-associated protein -|--|||||-|||---||------------|-----||----||||||-|--|--|---------- 2 [E] COG1586 S-adenosylmethionine decarboxylase ------------------||-------|||-------|----|||||--|--||||---|||||-- 2 [P] COG1613 ABC-type sulfate transport system, periplasmic component ---|----|-||||--|-||-|----||||----||||----||||||-|--|--|---||||||| 2 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 -------------|||-----|--|||---------------|||||-||||||||---|||||-- 2 [L] COG1643 HrpA-like helicases -------------------|-|--||---------||-----|||-|-||-|||||---|||||-- 2 [S] COG1652 Uncharacterized protein containing LysM domain ---|||||--|||----|||-|--|-||||||||-|||----|||||-||-||--|---||||--- 2 [G] COG1653 ABC-type sugar transport system, periplasmic component --|-----|-------|-||------|||||||-||||--------|-||-||||---|-|||||| 2 [G M] COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component |-|-------------||--|---------|----|||--------|-||-----|---||-|--- 2 [S] COG1683 Uncharacterized conserved protein --------------------|-||||||||||||||||----|||||-||||||||---||||||| 2 [M] COG1686 D-alanyl-D-alanine carboxypeptidase |||||||||||||--|||-|-|----|||-|------|----|||-|--|-----|---------- 2 [S] COG1690 Uncharacterized conserved protein --|---|||||||---|||||||||||||-||--||||----|||||-|||||------|||||-| 2 [R] COG1694 Predicted pyrophosphatase -||--------------|--|---|-------||-|--||---|||---|-|---|---|||||-- 2 [S] COG1704 Uncharacterized conserved protein |--------|--------||-------||||----|||----------|||--||||||||||||| 2 [S] COG1714 Predicted membrane protein/domain --------------------||----||||||||||||----|||||-||||-|||||||||||-- 2 [E] COG1760 L-serine deaminase ----||---------------|----|----|--|||---|||||-|-||--|--|---|||||-- 2 [O] COG1764 Predicted redox protein, regulator of disulfide bond formation -||-||||-|-||---||---|----|||-|----|-|--|||||||-||---|||---||-||-- 2 [O] COG1765 Predicted redox protein, regulator of disulfide bond formation ||-----||--------||||---|--||-|-----------|||-|--|--||||-------|-- 2 [C] COG1773 Rubredoxin --------|--|--------||----|||-|-|---||----|------||----|||-|||||-| 2 [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit --|-|||||-|||---||-|-|------------||||----|||||-||-|---|---||-||-- 2 [S] COG1801 Uncharacterized conserved protein ------|||-------|-|||---------|-----|-----|||||--|--||||---|||||-- 2 [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family --||||--|||||---|-||-|----||||----||||----|||||-|||||||||||||||||| 2 [U] COG1826 Sec-independent protein secretion pathway components |-|-|-|||-|||-|-||||||----||||||-|||||----|||||--|-|-|||---||||||| 2 [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family --|-------------|----|--------------------|||||-||-|---|||||--|--- 2 [P] COG1858 Cytochrome c peroxidase ----------------||----||||----|----|||----||||||||-----|||||||||-- 2 [N U] COG1886 Flagellar motor switch/type III secretory pathway protein ---|--|||-|-|||-|--|------|||-|||-||||----|||||-||-----|------||-- 2 [H] COG1893 Ketopantoate reductase ----||-----|-||----|||----||||||-|||||----|||||--|||||||---||||--- 2 [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family ||||||||--||----|||||-----||--|||--|||-------||--|-----||||||||--- 2 [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain -------------|-|----------||||------------|||||-|||||------|||||-- 2 [I] COG1946 Acyl-CoA thioesterase -----------||||---------------------|-----|||||--|-----|----||||-- 2 [F H] COG1953 Cytosine/uracil/thiamine/allantoin permeases ----------|||--------|-----||-------||----|||----|-----|---|||||-- 2 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family ------------------|||------||||--|||||----|||||-||||---|----|----- 2 [E] COG1982 Arginine/lysine/ornithine decarboxylases ----------------|-|||----------------|----|||||-||-|||||||||||||-- 2 [H] COG1995 Pyridoxal phosphate biosynthesis protein ---|---------||--|-|||--------|---||-|----|||||-||-----|---|||||-- 2 [E] COG2008 Threonine aldolase --------------------||-||-|---||||||||----|||||-||||||||||||||||-- 2 [P] COG2011 ABC-type metal ion transport system, permease component ---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||-- 2 [C] COG2025 Electron transfer flavoprotein, alpha subunit --||||--|-|||---|--|-|----|||-------|-----|||||--|-|---|--||||||-- 2 [R] COG2041 Sulfite oxidase and related enzymes -----------|--------||----|||-|-|---||----|------||----|||-|||||-| 2 [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit ||-|||--||||------|||---------|----|----------|--|-----|---||||--- 2 [H] COG2073 Cobalamin biosynthesis protein CbiG |---||----||||------------|||-------||----|||-|--|-----|---||-|--- 2 [R] COG2079 Uncharacterized protein involved in propionate catabolism ------------------||----------||||||||----|||||-||||---|---|||-|-- 2 [R] COG2081 Predicted flavoproteins ---|||--|-|||||--|--||----|||||-----||----|||-|--|--||||---|||||-- 2 [C] COG2086 Electron transfer flavoprotein, beta subunit --|-||||||||||--||--||-----||---|-||------|||-|--|-----|------|--- 2 [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 --|-----|----------|-|----|||||--||-||----|||||--|---|||---|||||-- 2 [S] COG2128 Uncharacterized conserved protein ---|---------||----|--------------|-|-----|||-|--|-----|------||-- 2 [R] COG2130 Putative NADP-dependent oxidoreductases ---|------|--||-|--|------|||-------||----|||||--|||||||--||||||-- 2 [Q] COG2132 Putative multicopper oxidases ----------|-------||-|---|-|||-------|----|||-|--|--|--|---||-||-- 2 [G] COG2133 Glucose/sorbosone dehydrogenases --||||----||--|---||-|----||------|-||----|||||--|--|--|---||-||-- 2 [P R] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases ---------------------------||--|---|||----|||||-||-----|---|||||-| 2 [F] COG2169 Adenosine deaminase -|----||-|--------|--|---------------------------|-----|----|-|--- 2 [O] COG2192 Predicted carbamoyl transferase, NodU family |-||--||||---||-|--|-------||-|-----||----|||-|-||--|----------|-- 2 [R] COG2234 Predicted aminopeptidases -|-|--||------|--|||||--|||---||||||||-|--|||||-||||-||||||-||-|-- 2 [R] COG2252 Permeases ------||-----||-||||||||--|||-||||||||----|||||-||||||||--||||||-- 2 [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase ------------------||----------||-|--||||||-||||-||--||||----|-||-- 2 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain --|-----|--||-----||||---|||||------||----|--||-||------------|--- 2 [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain ------------------|--|-----|||-------------------|-----|---||-||-- 2 [S] COG2307 Uncharacterized protein conserved in bacteria -----------|------|--|-----|||-------------------|-----|---||-||-- 2 [S] COG2308 Uncharacterized conserved protein -||---------------||-|---|-||--|--|-||-----------|-----|---------- 2 [S] COG2314 Predicted membrane protein --|---------------|-||--------------||----|||||-||---|||---|||||-- 2 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) ------||--|||-|------|||-----------|-|-----------|-----|---|||||-- 2 [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog ---|----|---|-----|--|---------------|----------||-|--------||--|| 2 [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component --------|-||---------|--------------||-------||--|-|-------------- 2 [Q] COG2368 Aromatic ring hydroxylase ---|||---|||-----|---|------------|-------|||||-||--|--|--|||||--- 2 [R] COG2391 Predicted transporter component |-||||--|||||||-----------|-------|----------|---|-----|---||||--- 2 [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog ------------------------------------------|||||-||--|----------|-- 2 [E] COG2716 Glycine cleavage system regulatory protein -------------------|------|||-||--||-|----|||-|--|-----|----|-||-- 2 [S] COG2764 Uncharacterized protein conserved in bacteria --|-----|-------|-||-|--------------|-----------||-----|---||-|--- 2 [T] COG2770 FOG: HAMP domain -|----||-|-|-----|---|---------|||||||----||||||||||-------|||||-- 2 [J] COG2813 16S RNA G1207 methylase RsmC --------------------------||||-|||||-|----|||||-||||-|||---|||||-- 2 [L] COG2818 3-methyladenine DNA glycosylase ---------------------|--------|-----------|||||-||||-|||----|---|| 2 [R] COG2823 Predicted periplasmic or secreted lipoprotein --------------------|---------------------|||||-||||||||--|----||| 2 [M] COG2853 Surface lipoprotein --|----------||---|-----------------||----|||||--|---|||-------|-- 2 [E] COG2866 Predicted carboxypeptidase |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 2 [H] COG2896 Molybdenum cofactor biosynthesis enzyme |--|------|||||-|--|-|----||||-------|----|||||-||-----|---|||||-- 2 [P] COG2897 Rhodanese-related sulfurtransferase -----------------|------------------------|||||-|||||||||||||-||-- 2 [S] COG2908 Uncharacterized protein conserved in bacteria --------------------|----------||-|--------|--|--||||||----|||||-- 2 [K] COG2932 Predicted transcriptional regulator --------------------------|-------||||----|||||-||||---|---|||||-- 2 [R] COG2962 Predicted permeases ------------------------------------------|||||-||---|||----|||-|| 2 [M] COG2982 Uncharacterized protein involved in outer membrane biogenesis ----------------|---|-||--|-----||--------------||-----|---||||-|| 2 [R] COG2984 ABC-type uncharacterized transport system, periplasmic component ---|||--------------||----------|-|-||-------||-||-----|---|||||-- 2 [E] COG2986 Histidine ammonia-lyase ------------------------------------------------||---|||||||||||-- 2 [C] COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit -------------||---||-------||-------------------||-----|---||-||-- 2 [I] COG3000 Sterol desaturase ------------------------------------------|||||-||---------|-||--- 2 [S] COG3126 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-------------|-- 2 [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit ------------------------------------------|||||-||---------------- 2 [S] COG3148 Uncharacterized conserved protein ------------------------------------------|-----||-----|---------- 2 [U] COG3149 Type II secretory pathway, component PulM -------------------------------|--||------|||||-||----------|-||-- 2 [S] COG3152 Predicted membrane protein --|----------------|------|----|--||------|||||-||---------|||||-- 2 [R] COG3153 Predicted acetyltransferase ------------------------------------------|--|--||--|--|------||-- 2 [U] COG3156 Type II secretory pathway, component PulK ------------------------------------------------||--||||---------- 2 [N U] COG3170 Tfp pilus assembly protein FimV ------------------------------------------|||||--|||-||----------- 2 [S] COG3171 Uncharacterized protein conserved in bacteria --------------------|-----|---------||--------|-||-|---|---||----- 2 [S] COG3181 Uncharacterized protein conserved in bacteria ------------------||------|---------------------||-----|---||-||-- 2 [E R] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins ---||||||--||------------------------------------|---------------- 2 [S] COG3199 Uncharacterized conserved protein ---|--------------------------------------------||---|---------|-- 2 [S] COG3205 Predicted membrane protein --|-----------------|-----------|-||||----------||---||-------||-- 2 [S] COG3212 Predicted membrane protein -------------------------------------------------|||-||----------- 2 [S] COG3219 Uncharacterized protein conserved in bacteria ------------------------------|------------------|||-|||----|--|-- 2 [S] COG3220 Uncharacterized protein conserved in bacteria ------------------||----||-----------------------|---------------- 2 [N] COG3225 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component ---------------------|---------------------------|---||----|------ 2 [P] COG3230 Heme oxygenase ---------------------|-----------------------||-||-|---|-----|---- 2 [E] COG3232 5-carboxymethyl-2-hydroxymuconate isomerase -------------------|-|----|---||--||------|||-|--|-|-------|--|--- 2 [S] COG3238 Uncharacterized protein conserved in bacteria ------------------||-------||-------|------------|-----|----|-||-- 2 [I] COG3239 Fatty acid desaturase -------------------|--------------------------|-||-||--|---------- 2 [I R] COG3240 Phospholipase/lecithinase/hemolysin --------|---------|--------|||------------------||-----|---||-|||| 2 [I] COG3243 Poly(3-hydroxyalkanoate) synthetase ------------------|------------------------------|-----|--|--|---- 2 [C] COG3258 Cytochrome c ------------------|-----------------------|||||--|||---|---|||||-- 2 [M] COG3264 Small-conductance mechanosensitive channel ---------------------------||-----------------|-||---------------- 2 [U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase) |-|----------------------------------------------|---|||--|------- 2 [R] COG3271 Predicted double-glycine peptidase ------------------------------------------|||||-||||-------------- 2 [K E] COG3283 Transcriptional regulator of aromatic amino acids metabolism -------------------|----------|-----||----|-----||-----|---|||||-- 2 [Q K] COG3284 Transcriptional activator of acetoin/glycerol metabolism ------------------||-------|-|------------|||||-||||-|||---||||||| 2 [C] COG3288 NAD/NADP transhydrogenase alpha subunit ------------------|-----------------|---------|--|-----|---||-||-- 2 [T] COG3300 MHYT domain (predicted integral membrane sensor domain) ------------------------------------------|||||-||-----|----||||-- 2 [R] COG3313 Predicted Fe-S protein --|----------------||------|||------|-----------||-|--------|-|--- 2 [Q] COG3315 O-Methyltransferase involved in polyketide biosynthesis -------------------|------||||------|-----|||||--|-----|-----||--- 2 [Q] COG3319 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases --|-----|------------------------------------|--||----------|--|-- 2 [T] COG3322 Predicted periplasmic ligand-binding sensor domain --------------------|-----|----------|--------|-||-|---|---||----- 2 [S] COG3333 Uncharacterized protein conserved in bacteria --|-|------|--|---------------|-----------|||||--|-|---|-------|-- 2 [S] COG3384 Uncharacterized conserved protein -----------------|||-|--|-----|-----------------||--|------------- 2 [K T] COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain -------------------------------------------|||--||---------|--|--- 2 [T] COG3456 Uncharacterized conserved protein, contains FHA domain --------------|------------------------------|---|-----|--|---||-- 2 [R] COG3491 Isopenicillin N synthase and related dioxygenases ------------------------------------------------||------------|--- 2 [S] COG3495 Uncharacterized protein conserved in bacteria -----------|---------------||--------------------|-----|------||-- 2 [M] COG3511 Phospholipase C -------------------------------------------||||-||-----|------|--- 2 [S] COG3521 Uncharacterized protein conserved in bacteria ---------------------------------------------|--||-----|------|--- 2 [O] COG3531 Predicted protein-disulfide isomerase -------------------------------------------------|---|||---||||--- 2 [S] COG3536 Uncharacterized protein conserved in bacteria -------------------|--------------------------|--|--|--|-----||--- 2 [O] COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases --------------------------------||-|------|||-|--|--|--|---|||||-- 2 [R] COG3568 Metal-dependent hydrolase -------------------------------------------------|---------||||||| 2 [R] COG3577 Predicted aspartyl protease ----------------|-------|-----------------|||-|-||-----|----|-|--- 2 [K T] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains --|-----------|----------|-----|------|----------|-----|---|--||-- 2 [F] COG3613 Nucleoside 2-deoxyribosyltransferase -------------------------------||--|-------|||---||-|--------|---- 2 [K] COG3617 Prophage antirepressor --------------------------|---------------|||||--|||---|----|||--- 2 [G] COG3622 Hydroxypyruvate isomerase --||-----------------|-----||-------|------------|---------|--||-- 2 [R] COG3631 Ketosteroid isomerase-related protein ---|---------------||-----|----|--|--|-|--||||---|---------||-||-- 2 [P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component ---------------------|---------------------------|----------|-||-- 2 [S] COG3652 Predicted outer membrane protein -------------------|------|---|-||-|||-----------|-------------|-- 2 [K] COG3655 Predicted transcriptional regulator --|----------------||---------|-|||--|-----------|---------||--|-- 2 [L] COG3666 Transposase and inactivated derivatives --------------------|------||||----|-------------|-----|---||-||-- 2 [T] COG3707 Response regulator with putative antiterminator output domain -------------------|----------------|-----|||-|--|-------------|-- 2 [R] COG3729 General stress protein -------------------------------------------------|--|----------|-- 2 [P] COG3746 Phosphate-selective porin -------------------------------------------------|-----|---|||||-- 2 [S] COG3749 Uncharacterized protein conserved in bacteria ------------------------------------------|||||--|||-------------- 2 [M] COG3765 Chain length determinant protein -------------------------------------------------|||-||----------- 2 [S] COG3767 Uncharacterized low-complexity protein ------------------------------------------|||||-||---------------- 2 [S] COG3776 Predicted membrane protein -------------------------------------------------|-----|---||-||-- 2 [S] COG3795 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|---|||||-- 2 [S] COG3803 Uncharacterized protein conserved in bacteria ----------------|-------------|----|||----|||-|--|-----|---------- 2 [K T] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains |||||||||||||---||||||--|-||||||||||||-||||||||-||-||--|--|||||--- 2 [G] COG3839 ABC-type sugar transport systems, ATPase components --------------------------|---||--||-------------|-----|---||-|--- 2 [S] COG3865 Uncharacterized protein conserved in bacteria -------------||----------------------------------|---------|||||-- 2 [R] COG3897 Predicted methyltransferase ---------------------------------------------|---|-----|---||-|--- 2 [T Q] COG3916 N-acyl-L-homoserine lactone synthetase -------------------------------------------------|---------||||--- 2 [E] COG3938 Proline racemase --||--------|-|-|-||||----||||||||||||-----------|---||-------|--- 2 [R] COG4122 Predicted O-methyltransferase ---------------------------------------------||--|-----|---||----- 2 [S] COG4125 Predicted membrane protein --------------------|---------------------|||||-||-----|---||||--- 2 [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component ------------------------------------------|||||-||-----|||-||||--- 2 [R] COG4174 ABC-type uncharacterized transport system, permease component --|----------------------|-----||--||-----|||||--|-----|---||||--- 2 [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component --|----------------------|-----||--||-----|||||--|-----|---||||--- 2 [E] COG4176 ABC-type proline/glycine betaine transport system, permease component ----------------------||------------------|||||-||||||||--|----|-- 2 [O C] COG4232 Thiol:disulfide interchange protein -------------------------|----------------|||||-||-----|||-||||--- 2 [R] COG4239 ABC-type uncharacterized transport system, permease component ---------------------------------------------|---|-----|---------- 2 [S] COG4253 Uncharacterized protein conserved in bacteria -------------------|----------------|------------|-----|----|-|--- 2 [S] COG4319 Ketosteroid isomerase homolog ------------------||-|----|||-||||||||-----------|-----|---||-||-- 2 [T] COG4585 Signal transduction histidine kinase --|-------------|---||--||----|-----------|||||||||||||||||||||||| 2 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component ----------------|----------------------------|---|---------||-|||| 2 [R] COG4618 ABC-type protease/lipase transport system, ATPase and permease components ------------------------------------------|||||-||||-------------- 2 [M] COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein ------------------------------------------|||----|-----|---------- 2 [S] COG4676 Uncharacterized protein conserved in bacteria --------------------------|----------------------|-----|-----|---- 2 [R] COG4757 Predicted alpha/beta hydrolase ---|----------------------||||-------------------|-----|---||||||| 2 [I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit ------------------------------------------|------|------||--|--|-- 2 [P] COG4772 Outer membrane receptor for Fe3+-dicitrate ------------------------------------------|||----|--|----------|-- 2 [P] COG4774 Outer membrane receptor for monomeric catechols ----------------|-------------------------|||||-||||||||---------- 2 [N U] COG4969 Tfp pilus assembly protein, major pilin PilA ------------------------------------------------||--||||------|--- 2 [N U] COG4970 Tfp pilus assembly protein FimT |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-- 2 [E] COG4992 Ornithine/acetylornithine aminotransferase ------------------------------------------|||-|--|---------||-|--- 2 [G] COG4993 Glucose dehydrogenase ----|------|----------||-------------------------|----------|----| 2 [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C |||---|||||||||-||||-|----||||||--||||----||||||||-|||||--||||||-- 1 [E] COG0002 Acetylglutamate semialdehyde dehydrogenase |||||||||||||||-||||-------||||-||-|||----|--||--|--|------||-|--- 1 [F] COG0005 Purine nucleoside phosphorylase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0012 Predicted GTPase, probable translation factor |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0013 Alanyl-tRNA synthetase --|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||-- 1 [E] COG0014 Gamma-glutamyl phosphate reductase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0018 Arginyl-tRNA synthetase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 1 [I] COG0020 Undecaprenyl pyrophosphate synthase -------------|||||||-||||-||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0021 Transketolase |||||||||||||||---||----------------------|||||-||||-------------- 1 [J] COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related proteins ---|||----||-||-||||-|----||||-|||||||----|||||-||||||||---|||||-- 1 [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) -|----||---|------||------|||-------|-----|||||-||-|-------------- 1 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) ---|--||---|----|-|||------||||----|||----|||||-||--||||---||-||-- 1 [H] COG0029 Aspartate oxidase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase |--|---|--|||||-||||||--|-|||-|||||||||||||||||-||||-|||--||||||-- 1 [F] COG0035 Uracil phosphoribosyltransferase -|--||-------||||||||||||-||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0036 Pentose-5-phosphate-3-epimerase ||||----||||-||-||||-|----||||||--||||----|||||||||||||---||||||-- 1 [E] COG0040 ATP phosphoribosyltransferase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase ||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--|||||||| 1 [C] COG0045 Succinyl-CoA synthetase, beta subunit ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0048 Ribosomal protein S12 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0049 Ribosomal protein S7 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0051 Ribosomal protein S10 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0052 Ribosomal protein S2 ||||---||||||||-||||||---||||-||||||||----|||||-||-|---|--|||||||| 1 [P] COG0053 Predicted Co/Zn/Cd cation transporters ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 1 [H] COG0054 Riboflavin synthase beta-chain --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0055 F0F1-type ATP synthase, beta subunit --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0056 F0F1-type ATP synthase, alpha subunit -||---||--||-|--|-||||||--|||-||||--||----|||||-||||-------||-|--- 1 [G] COG0058 Glucan phosphorylase |||----|||||-|--||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E H] COG0059 Ketol-acid reductoisomerase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0060 Isoleucyl-tRNA synthetase |||||||||||||||||||||---|||||||||||||||-|||||||||||||||||||||||||| 1 [G] COG0061 Predicted sugar kinase |||||||||||||||-||||-|----|||||-----------|||||-||--|--|||||||||-- 1 [S] COG0062 Uncharacterized conserved protein ||||||||||||||||||||-|----||||||--|||-----|||||-||--||||||||||||-- 1 [G] COG0063 Predicted sugar kinase ||||----||-||||-||||||||||||||||||||||||||-------|---||||||||||||| 1 [J] COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) ||||--||||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0065 3-isopropylmalate dehydratase large subunit |||---||||||-||-||||-|----||||||-|||||----||||||||||||||--||||||-- 1 [E] COG0066 3-isopropylmalate dehydratase small subunit |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 1 [E] COG0067 Glutamate synthase domain 1 |||-----||||-||-||||-|----||||||--||||----|||||-||--|--|--||||||-- 1 [E] COG0070 Glutamate synthase domain 3 |||||||||||||||-||||-|-----||||---|-||----||||||||--|--|---||||||| 1 [O] COG0071 Molecular chaperone (small heat shock protein) |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit ||-|||--|||||||-|-||-|||--||||----|-||----|||||-||||||||--|||||||| 1 [C] COG0074 Succinyl-CoA synthetase, alpha subunit ||||||||||||||--||||-|--------||--|-||--------|-||------||-||-||-- 1 [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase ||||||--||||-||-||||-|----||||||-|||||----|||-||||||||||--||||||-- 1 [E] COG0077 Prephenate dehydratase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0080 Ribosomal protein L11 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0081 Ribosomal protein L1 ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0082 Chorismate synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0087 Ribosomal protein L3 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0088 Ribosomal protein L4 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0089 Ribosomal protein L23 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0090 Ribosomal protein L2 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0091 Ribosomal protein L22 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0092 Ribosomal protein S3 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0093 Ribosomal protein L14 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0094 Ribosomal protein L5 ---|||||---||||-||||--||--|----|||||||-||||||||-||---------------- 1 [H] COG0095 Lipoate-protein ligase A |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0096 Ribosomal protein S8 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0097 Ribosomal protein L6P/L9E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0098 Ribosomal protein S5 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0099 Ribosomal protein S13 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0100 Ribosomal protein S11 |||||||||||--||||||||||||||||||||||||||-|||||||||||||||||||||||||| 1 [J] COG0101 Pseudouridylate synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0102 Ribosomal protein L13 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0103 Ribosomal protein S9 ||||||||||||-||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0104 Adenylosuccinate synthase |||||||||||||||||-||-||||||||||--|||||----|||||-|||||||||||||||||| 1 [F] COG0105 Nucleoside diphosphate kinase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 1 [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase ||||||--|||||||-|-||||||--|||||---||||----|||||-||-||||||||||||||| 1 [H] COG0113 Delta-aminolevulinic acid dehydratase -|----|||||-|-----|-||--------||||||||----||||||||||||||---------- 1 [L] COG0116 Predicted N6-adenine-specific DNA methylase -------------||-||||||||--||||||-||-||----||||||||||||||||||||||-- 1 [H] COG0117 Pyrimidine deaminase ||||||||||||||||--||-|||||----||||||------||||||||||||||---|||||-- 1 [G] COG0120 Ribose 5-phosphate isomerase ||--|-||--||-|----||-------||-------------|||||-||||-|||---||||--- 1 [R] COG0121 Predicted glutamine amidotransferase |-||--|||---||||--|--|-----||-|-----||-|--|||||-||--|--|---|||||-- 1 [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0124 Histidyl-tRNA synthetase ||||||||||||||||||||||||||||||-||||||||||||||||||||||||||||||||||| 1 [F] COG0125 Thymidylate kinase ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0126 3-phosphoglycerate kinase ||||||||||||||||||||||||||||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0127 Xanthosine triphosphate pyrophosphatase ||||||-||||||||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase ||||||||||||||||||||||||||||||||||||||||--||||||||||||||--|||||||| 1 [J] COG0130 Pseudouridine synthase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0131 Imidazoleglycerol-phosphate dehydratase -|-----------|--|-|||--|--|||||---|-||----||||||||||||||||||-|||-- 1 [H] COG0132 Dethiobiotin synthetase ||||---|||---||-|||||||---||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0133 Tryptophan synthase beta chain ||||||-||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0134 Indole-3-glycerol phosphate synthase ||||||-||||||||-||||-||---|---||-|||||----||||||||||||||||||||||-- 1 [E] COG0135 Phosphoribosylanthranilate isomerase ||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0137 Argininosuccinate synthase --||||--|----||-||||||----||||||-|||||----||||||||||||||--||||||-- 1 [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase ||||-----|||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase ||||----||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0141 Histidinol dehydrogenase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0143 Methionyl-tRNA synthetase -|-|--||||||||||-|||||||--|||-||||||||----|||||-||||||||--||||||-- 1 [J] COG0144 tRNA and rRNA cytosine-C5-methylases ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0148 Enolase ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-- 1 [G] COG0149 Triosephosphate isomerase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0150 Phosphoribosylaminoimidazole (AIR) synthetase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||||||||||-- 1 [F] COG0151 Phosphoribosylamine-glycine ligase ||||||||||||-||-||||||----||||||||||||----|||||-||||||||--|||||||| 1 [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase -|--||||-----||||-||||||---|||----|-||----|||||-|||||||||||||||||| 1 [H] COG0156 7-keto-8-aminopelargonate synthetase and related enzymes ||||--||||||-|--|||||-----|||||-||-|||----|||||-||||||||||-||-||-- 1 [H] COG0157 Nicotinate-nucleotide pyrophosphorylase ---|---------||---||----------------------|||||-||||-||||||-||-|-- 1 [G] COG0158 Fructose-1,6-bisphosphatase ||||||-||||||||-||||-||---||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0159 Tryptophan synthase alpha chain |||-||||||||||--|-||-|||------------||----|||||-||-|-|||||||||-||| 1 [H] COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase ||||||||||||||||||||||||-|||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0164 Ribonuclease HII ||||||--||||-||-||||-|----||||||--||||----||||||||||||||--||||||-- 1 [E] COG0165 Argininosuccinate lyase -|-|||----||||||||||||||||||||||||||||-|||||||||||||||||||||||||-- 1 [G] COG0166 Glucose-6-phosphate isomerase ||||--||||--|||-||||||--||------||||||-||||||||-||||-||---||||---- 1 [P] COG0168 Trk-type K+ transport systems, membrane components |||||||||||||||-||||||--||||||||||||||||||||||||||--||||||||||||-- 1 [H] COG0171 NAD synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0172 Seryl-tRNA synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0173 Aspartyl-tRNA synthetase -|--||-------||-||||-|||--|||||-||||||----||||||||||-|||||||||||-- 1 [G] COG0176 Transaldolase ||||||||||||||||||||||||||||||||||||||----|||||||||||||||||||||||| 1 [L] COG0177 Predicted EndoIII-related endonuclease |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0178 Excinuclease ATPase subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0180 Tryptophanyl-tRNA synthetase ||||||--|||||||-|-||||||--|||||---||||----||||||||-||||||||||||||| 1 [H] COG0181 Porphobilinogen deaminase |||-|||||||||||-|||||---------------|------------|--|-------|-|--- 1 [J] COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0184 Ribosomal protein S15P/S13E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0185 Ribosomal protein S19 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0186 Ribosomal protein S17 --||||----||-||-|||||||||||||||||||||||||||||||||||||-|||||||||||| 1 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase -------------||-||||-|--||||||||||||||||||||||||||||-||||||-||||-- 1 [G] COG0191 Fructose/tagatose bisphosphate aldolase -------------||-||||||--||||||||||||||||||||||||||||||||||||||||-- 1 [H] COG0192 S-adenosylmethionine synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0193 Peptidyl-tRNA hydrolase -------------|||||||||||--|||||||||||||||||||||||||||||||||||||||| 1 [F] COG0194 Guanylate kinase |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0195 Transcription elongation factor -------------||-|||||||||-||||||||||||||||||||||||||||||||||||||-- 1 [H] COG0196 FAD synthase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0197 Ribosomal protein L16/L10E |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0198 Ribosomal protein L24 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0199 Ribosomal protein S14 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0200 Ribosomal protein L15 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0201 Preprotein translocase subunit SecY ||-||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0203 Ribosomal protein L17 ||||||||||------||||||--||||||||||||||-||||||||||||||||||||||||||| 1 [D] COG0206 Cell division GTPase |||-----||---|||----||----||||||||||||-|||||||||||||||||---|||||-- 1 [F] COG0207 Thymidylate synthase ---|-------|-||||-|-|||||-||||||||||||-|||||||||||||||||||||-|-||| 1 [F] COG0208 Ribonucleotide reductase, beta subunit -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0211 Ribosomal protein L27 |--|-----||||||-|-|||||||-||||||-|||||--|||||||-|||||||||||||||||| 1 [H] COG0212 5-formyltetrahydrofolate cyclo-ligase --|||||||-|||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0215 Cysteinyl-tRNA synthetase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0216 Protein chain release factor A -------------||-|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [S] COG0217 Uncharacterized conserved protein -|||--||||---|--||--|---------|||||||||||||||||||||||||||||||||||| 1 [R] COG0218 Predicted GTPase ------------------||||||--|||||||||-|||||||||||-||||||||--||||||-- 1 [J] COG0219 Predicted rRNA methylase (SpoU class) -------------||||||||||||-|||||||||||||||||||||||||||||||||||||||| 1 [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase |-||||||-|-||||||-||||||--|||||----|-||||||||||||||||||||||||||||| 1 [C] COG0221 Inorganic pyrophosphatase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0222 Ribosomal protein L7/L12 --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0224 F0F1-type ATP synthase, gamma subunit |-||-------|-||---||||--|-|||||||||||||||||||||-||||||||||||||||-- 1 [O] COG0225 Peptide methionine sulfoxide reductase -------------||-|||||||||||||-|||||||||||||||||||||||||||||-|||||| 1 [J] COG0227 Ribosomal protein L28 -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0228 Ribosomal protein S16 |-||---------||---||||--|-|||-||||||||-||||||||-||||||||||||||||-- 1 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase -------------||-||||-||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0230 Ribosomal protein L34 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0233 Ribosome recycling factor --|----------||-||||||||||||||||||||||--|||||||||||||||||||||||||| 1 [O] COG0234 Co-chaperonin GroES (HSP10) ||||||||||||||||||||||||||||||||||||||-||||||||||||||||||||||||||| 1 [H] COG0237 Dephospho-CoA kinase -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0238 Ribosomal protein S18 -|||--||-|---||-||||-|----|||-|--|||||----|||||-||||||||||||||||-- 1 [D] COG0239 Integral membrane protein possibly involved in chromosome condensation |-------|----|||||||||||||||||||||||||||--|||||-|||||||||||||||||| 1 [C] COG0240 Glycerol-3-phosphate dehydrogenase -|--||-------|||--|-|------||-|-----------|||||||||||||||||---||-- 1 [E] COG0241 Histidinol phosphatase and related phosphatases |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0244 Ribosomal protein L10 ----------------|||||||||-|||||----|||--||||||||||||||||||||||||-- 1 [I] COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase -------------|---|--------|---||-||-||-||-||||||||-|---|---|||||-- 1 [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases --|--------|-|--||||||----|||||------|----|||||-|||||||||||||||||| 1 [F P] COG0248 Exopolyphosphatase --||-|-------|||||||||||||----|||-||||----||||||||||||||---||||||| 1 [L] COG0249 Mismatch repair ATPase (MutS family) |||||||||||||-|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0250 Transcription antiterminator ||------||------|||||-||--|||||---||||----|||||||||||||||||||||||| 1 [E] COG0253 Diaminopimelate epimerase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0255 Ribosomal protein L29 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0256 Ribosomal protein L18 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) ------------|-|||-||||||--||||----|-|||||||||||||||||-|||||||||||| 1 [E] COG0260 Leucyl aminopeptidase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0261 Ribosomal protein L21 --|----------||-||||-|--|-||||||||-|||----|||||-||||||||--||||||-- 1 [E] COG0263 Glutamate 5-kinase --------------|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0264 Translation elongation factor Ts ------------------||-|----||||-||||||||||||||||-||||||||---|||||-| 1 [L] COG0266 Formamidopyrimidine-DNA glycosylase -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0267 Ribosomal protein L33 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0268 Ribosomal protein S20 ---|---------||---||----------------------||||||||||||||---||||||| 1 [T] COG0271 Stress-induced morphogen (activity unknown) ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis ----||-------||-|-||-|||--||||-|-|||||----|||||-|||||||||||||||||| 1 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) ---|---------|||--||----------------------||||||||||||||---||||||| 1 [O] COG0278 Glutaredoxin-related protein -|--||----------|-|-|------||-|-----------||||||||||-||-|||---|--- 1 [G] COG0279 Phosphoheptose isomerase --||-------------||-||--|||||-||||||||||||||||||||||||||-||||||||| 1 [C] COG0280 Phosphotransacetylase --|--------------|||||--|||||-||||||||||||||||||||||-||-|||-|||-|| 1 [C] COG0282 Acetate kinase ---------------||||||||||||||||||||||||||||||||-||||||||---||||||| 1 [F] COG0283 Cytidylate kinase |||||||||||||||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [F] COG0284 Orotidine-5'-phosphate decarboxylase ---|||-------||-||||||--|-||||||||||||----|||||||||||||||||||||||| 1 [H] COG0285 Folylpolyglutamate synthase ||||---||----------|-------||--|||||--|||-|||-|-|||||||||||-||-|-| 1 [V] COG0286 Type I restriction-modification system methyltransferase subunit ||||||--|||||||-||||-|----||||||-|||||----|||||-||||||||||||||||-- 1 [E] COG0287 Prephenate dehydrogenase |||-----||------||||--||--|||-||-|||||----|||||||||||||||||||||||| 1 [E] COG0289 Dihydrodipicolinate reductase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0290 Translation initiation factor 3 (IF-3) -------------|--|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0291 Ribosomal protein L35 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0292 Ribosomal protein L20 ||||||--||---|||--------||----------------||||||||||||||---||||||| 1 [J] COG0293 23S rRNA methylase |||||||||||||||-||||||||--||||||||||||----|||||-||||||||||||||||-| 1 [H] COG0294 Dihydropteroate synthase and related enzymes -|----||--||--|-||||||||------||-|--||----|||||-||||---|---||-|--- 1 [G] COG0297 Glycogen synthase --||||----|--||-||||||----||||||||||||----|||||-||||||||--||||||-- 1 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN |||||||||||||----|------|-----|||||||||||||||||-||||-------------- 1 [H] COG0301 Thiamine biosynthesis ATP pyrophosphatase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0305 Replicative DNA helicase ---|---------||-||||||||--||||||-||-||----||||||||||||||||||||||-- 1 [H] COG0307 Riboflavin synthase alpha chain --|-||----||-|||--||-|----||||-|||--------|||||-||||||||---|||||-- 1 [E] COG0308 Aminopeptidase N ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0313 Predicted methyltransferases |||||||||-|||---|-||-|----|||-----||||----|||||-||||---|||||||||-- 1 [H] COG0314 Molybdopterin converting factor, large subunit |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 1 [H] COG0315 Molybdenum cofactor biosynthesis enzyme ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0319 Predicted metal-dependent hydrolase ---|------|||||-|-||-|||--||||----|-||----||||||||||||||---||||||| 1 [H] COG0320 Lipoate synthase ----------|--||---||-|----||||------------||||||||||||||---||||||| 1 [H] COG0321 Lipoate-protein ligase B |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0322 Nuclease subunit of the excinuclease complex --||---------|||||||||||||----||||||||----||||||||||||||---||||||| 1 [L] COG0323 DNA mismatch repair enzyme (predicted ATPase) -------------||-||||||||||||||||||||||----|||||||||||||||||||||||| 1 [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase --|----------||-||||||----||||||||||||----||||||||||||||||||||||-- 1 [R] COG0325 Predicted enzyme with a TIM-barrel fold ||||--||||---|||---|||||||||-|||||||||||--||||||||||-||||||------- 1 [S] COG0327 Uncharacterized conserved protein ---|------|--||---||-|--|-||||----||||----|||||-|||||||||||||||||| 1 [L] COG0328 Ribonuclease HI -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 1 [J] COG0333 Ribosomal protein L32 -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0335 Ribosomal protein L19 ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0336 tRNA-(guanine-N1)-methyltransferase ----||-|--|||||--|||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0337 3-dehydroquinate synthetase -------------||---||-|----|---------------|||||-||||||||---|||||-- 1 [E] COG0339 Zn-dependent oligopeptidases ||||--|||--|-||-|||||||||-||||||||||||----|||||-|||||||||||||||||| 1 [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase ||||--||-|------|||||||||||||||---||||-|--|||||-|||||||||||||||||| 1 [U] COG0341 Preprotein translocase subunit SecF |||||||||||||-||||||||||-||---||||||||----|||||||||||||||||||||||| 1 [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase ----------------||||||--------|||||||||||||||||-||||-|||||||||||-- 1 [S] COG0344 Predicted membrane protein |-|-||----|||||-||||-|--|-||||||||||||----|||||-||||||||||||||||-- 1 [E] COG0345 Pyrroline-5-carboxylate reductase |||-----||------||||-|----|||-||---||-----|||||-||||||||---|||||-- 1 [E] COG0347 Nitrogen regulatory protein PII -------------|----||------|||||-----------|||||-|||||------||||||| 1 [J] COG0349 Ribonuclease D |||||||||||||||-||-|||--|-||||||||||||----|||||-||||||||||||||||-- 1 [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase ----------------|-|||||||-||||||||||||||--|||||-|||||||||||||||||| 1 [L] COG0353 Recombinational DNA repair protein (RecF pathway) -------------||-|-||-|----||||------------||||||||||||||---||||||| 1 [R] COG0354 Predicted aminomethyltransferase related to GcvT --|----------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) --|----------|--|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0356 F0F1-type ATP synthase, subunit a ----------------||||||--|||||||||||||||||||||||-|||||||||||||||||| 1 [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0358 DNA primase (bacterial type) --------------|-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0359 Ribosomal protein L9 -------------||-|||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0360 Ribosomal protein S6 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0361 Translation initiation factor 1 (IF-1) -------------|||-||||-||||||||||||||||-|--|||||-||||||||||-|||||-- 1 [G] COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase |||||||||||||-----||||----|||-|----|-|----|||-|-||-----|---||||--- 1 [H] COG0368 Cobalamin-5-phosphate synthase -------------|||--||--||----------|-||----||||||||--|||----|-|-|-- 1 [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein) |||---|||||-----||||-|--------||--||------|||||-||--|--||||----|-- 1 [P] COG0370 Fe2+ transport system protein B ||||||--|||||---|-||||||--|||||---||||----|||||-||-||||||||------- 1 [H] COG0373 Glutamyl-tRNA reductase --|||||||-|||---||||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases |||-----||----|-|-||||----|||-----|--||---|||||--||----||||||||--- 1 [O K] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase ||||--||||||----|||||-----|||||----|||----|||||-||--||||||-||-||-- 1 [H] COG0379 Quinolinate synthase ||-|--||---------|||-|--------||-||||-----|||||-||-|-|||--|-----|| 1 [M] COG0381 UDP-N-acetylglucosamine 2-epimerase |||||||||||||||-|-||-|||--|||||------|----|||||-||-||||||||||||||| 1 [H] COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases -------------||---||------|----------|----|||-|-||--|--|---||--|-- 1 [S] COG0397 Uncharacterized conserved protein -------------||---||-|||-------|--||||----|||----|--|------||||-|| 1 [R] COG0400 Predicted esterase -------------||---||----------------------|||-|--|---------|------ 1 [S] COG0401 Uncharacterized homolog of Blt101 --|-||-------||-|-||-|||--||||----||||----|||||-||-||||||||||||||| 1 [H] COG0407 Uroporphyrinogen-III decarboxylase -------------||---||----------------------|||||-||--|--|---||||||| 1 [H] COG0408 Coproporphyrinogen III oxidase -------------||-||||-|----|||||---||||----||||||||--||||||||||||-- 1 [H] COG0414 Panthothenate synthetase |-||-------|-|----||------|-----|-||------||||||||----|----|--||-- 1 [L] COG0415 Deoxyribodipyrimidine photolyase ----------------||||||||------|||||||||||||||||-||-|-|||||||||||-- 1 [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme ||||||||||||||||---|----------------------|||||-||---------------- 1 [L] COG0417 DNA polymerase elongation subunit (family B) -------------||---|-----------------------||||||||---||||||||----- 1 [F] COG0418 Dihydroorotase ||||||||||||||||||||||--||----||--|||-----|||||-||---------------- 1 [L] COG0419 ATPase involved in DNA repair ||||||||||||||||||||||--||||||||--||||----|||||-||----------|----- 1 [L] COG0420 DNA repair exonuclease ||||---|||||----||||||----|||||-----||----|||||-||--||||--|||-||-- 1 [H] COG0422 Thiamine biosynthesis protein ThiC |||---|||-------|||||---------|-----------|||-|--|-----|---------- 1 [C] COG0426 Uncharacterized flavoproteins ||||--||--||||||||-|-|---||||------|------|||-|--|---|||--|-|----- 1 [P] COG0428 Predicted divalent heavy-metal cations transporter -------------|-|--||----------------------|||||-||---|||---------- 1 [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold ||||--|||||||||||--|----------------------|||-|--|-----|---------- 1 [A] COG0430 RNA 3'-terminal phosphate cyclase |||---|||||||-|-||||-|-----||-|-----||----|||-|-||---------||----- 1 [S] COG0432 Uncharacterized conserved protein |||||||||||||---||||-|-----||---|----|----||||---|-|---|---|||||-- 1 [R] COG0433 Predicted ATPase ---|---------||---||------|---------------|||-|-||---------||||--- 1 [O] COG0435 Predicted glutathione S-transferase --||---||-|||---|-------------------------|||||-||||---|--|-|-|--- 1 [C] COG0437 Fe-S-cluster-containing hydrogenase components 1 |||---||||--|||-||||-|----||||||-|||||----||||||||||-|||--||||||-- 1 [E] COG0440 Acetolactate synthase, small (regulatory) subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0441 Threonyl-tRNA synthetase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0442 Prolyl-tRNA synthetase --|||||||-|||---||--||||-||---|||||||||||||||||-||||---||||||||--- 1 [E P] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 1 [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division ||||||||-||||||||||||||||-||||||||||||----||||||||||||||||||||||-- 1 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains |||||||||||||||-||||||---|||||||||||||----|||||-||||||||||||||||-- 1 [H] COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase ||-|--||||------||-|----||-||||-----||----------||-----||||------- 1 [D] COG0455 ATPases involved in chromosome partitioning ||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||-- 1 [E F] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) ||||||||||||||||||||||||||||||||||||||--|||||||||||||||||||||||||| 1 [O] COG0459 Chaperonin GroEL (HSP60 family) |||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0460 Homoserine dehydrogenase |||||||||||||||-||||||-|--||||||||||||----||||||||||||||||||||||-- 1 [F] COG0461 Orotate phosphoribosyltransferase |||||||||||||||-||||||--||||||||||||||||||||||||||||||||||||||||-| 1 [F E] COG0462 Phosphoribosylpyrophosphate synthetase ||||||||||||||||--||-|----||||------||-----------|-----|--|||-|--- 1 [O] COG0464 ATPases of the AAA+ class -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0465 ATP-dependent Zn proteases |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0468 RecA/RadA recombinase |||||||||||||||||||||||||-||||-||||||||||||||||||||||||||||||||||| 1 [L] COG0470 ATPase involved in DNA replication ||-|--||-||--||-|-|--|||--|---|||||-||----|||||-||||||||||||||---- 1 [P] COG0471 Di- and tricarboxylate transporters |||---||||||-||-||||-|----||||||--||||----||||||||||||||--|||||||| 1 [C E] COG0473 Isocitrate/isopropylmalate dehydrogenase ||-|||--|||||||-|-||-|||--||||----|-||----|||||-|||||||||||||||||| 1 [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0481 Membrane GTPase LepA -------------||-||||||||-||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain ||||--||||||||--||||-|---|||||-|||||||----|-||||||||||||--|||||||| 1 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family |-||||-------||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain -------------||-||||||||||----|||||||||||||||||||||||||||||||||||| 1 [R] COG0486 Predicted GTPase ||||||||||||||||||||||----|||||--|||||----|||||-|||||||||||||||||| 1 [D] COG0489 ATPases involved in chromosome partitioning |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0495 Leucyl-tRNA synthetase ||||----|||-||--||||-||||-----------------|||||-||||||||||||||||-- 1 [R] COG0496 Predicted acid phosphatase ----------------|-||||--|-||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0497 ATPase involved in DNA repair |||||||||||||||-||||-|----||||||-|||||----||||||||||||||||||||||-- 1 [E] COG0498 Threonine synthase |||||||||||||||-||||------||||-------------------|--|--|---|||||-- 1 [H] COG0499 S-adenosylhomocysteine hydrolase |||------|---||-|||||--|--|||||---|-||----||||||||||||||||||-|||-- 1 [H] COG0502 Biotin synthase and related enzymes ||||||--||||-||-||||||----||||||||||||----||||||||-|||||||||||||-- 1 [E F] COG0505 Carbamoylphosphate synthase small subunit ---|---------||---||-|----|||-----|-||----|||||--|-|-|||||||||||-- 1 [E] COG0506 Proline dehydrogenase -|-----------||----|-|||-|-||-||||||||-|--|||||||||||||---|||||--- 1 [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member --|---------||||--||||--|-|---||--||||----|||||-||||||||---||-||-- 1 [L] COG0514 Superfamily II DNA helicase |||||||||||||||-||||||-|-|||||||||||||----|||||-||||||||||||||||-- 1 [F] COG0519 GMP synthase, PP-ATPase domain/subunit |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0522 Ribosomal protein S4 and related proteins |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0525 Valyl-tRNA synthetase |||||-|||||||||-||||-|||--||||||-|||||----|||||||||||||||||||||||| 1 [E] COG0527 Aspartokinases |||||||||||||---|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [F] COG0528 Uridylate kinase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0532 Translation initiation factor 2 (IF-2; GTPase) |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0533 Metal-dependent proteases with possible chaperone activity -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG0536 Predicted GTPase ---|||--|-|||||-||||-|-----||--|--||||----|||||--|-|---|||-|||||-- 1 [C] COG0538 Isocitrate dehydrogenases -------------||-||||||||||||||||||||||-|--|||||||||||||||||||||||| 1 [J] COG0539 Ribosomal protein S1 |||||||||||||||-||||||----||||||||||||----||||||||--||||||||||||-- 1 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0541 Signal recognition particle GTPase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) ---|||||--|-|-----|------------||||-----|-|||-|--||---------|----- 1 [E] COG0549 Carbamate kinase |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0550 Topoisomerase IA |||||||||--------|--|-|||-----|||||||||-|||||||||||||||||||------- 1 [L] COG0551 Zn-finger domain associated with topoisomerase type I |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0552 Signal recognition particle GTPase ||||||||||||------||-|-----||-|------|----|||||-||||||||---|||||-- 1 [O] COG0555 ABC-type sulfate transport system, permease component |-||------------|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0556 Helicase subunit of the DNA excision repair complex ---|---------||||||||||||-|---||||||||||||||||||||||||||||||||||-- 1 [K] COG0557 Exoribonuclease R ||||||--||-||-----||-|--------------------|||||-||||||||---|||||-| 1 [J] COG0565 rRNA methylase --------|----||-|||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [J] COG0566 rRNA methylases -------------||------|||--||||----|-||----||||||||||||||---||||||| 1 [C] COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes ||||--|||||-|---||||||--||-||---||||||-||||||||-||||-||---||||---- 1 [P] COG0569 K+ transport systems, NAD-binding component -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0571 dsRNA-specific ribonuclease |||||||||||||---||||||--|-|||||--|-||-----|||||-||--|||||||||||||| 1 [G] COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase |||||||||||||||||||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [I] COG0575 CDP-diglyceride synthetase |-||||-------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0576 Molecular chaperone GrpE (heat shock protein) ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 1 [P] COG0581 ABC-type phosphate transport system, permease component |||||||||--||---||||||||--||||||||||||||--|||||-|||||||||||||||||| 1 [L] COG0582 Integrase |||||||||||||||||----|--------------------|||||-||||----|||------- 1 [S] COG0585 Uncharacterized conserved protein |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog) -----------------||||||||||||||||||||||||||||||||||||||||||-|||||| 1 [J] COG0594 RNase P protein component ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M U] COG0597 Lipoprotein signal peptidase --|||||||-|||---||||||||-||||||||||||||||||||||-||||---||||||||--- 1 [E P] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components |||||||||||||---|-||----------|---|-||----|||||-|||||||||||||||||| 1 [R] COG0603 Predicted PP-loop superfamily ATPase |--------|------||||||---||||-|-----------|||||-||||||||||||||||-| 1 [O] COG0606 Predicted ATPase with chaperone activity ||||||||||||----|||||||||||---||||||||----|||||-|||||||||||||||||| 1 [L] COG0608 Single-stranded DNA-specific exonuclease ||||---||----------|-----------||-||--|||-------||||||--|||-||-|-| 1 [V] COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases |||||||||||||---|-||------||||------||----||||||||||||||--|----|-- 1 [H] COG0611 Thiamine monophosphate kinase ||||----|--||---||||-|--------|------|----|||||-||||-|||---------- 1 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) |||||||||||||||-||-----|--||||-|-|||||----||||||||||||||--||--||-- 1 [E] COG0620 Methionine synthase II (cobalamin-independent) ||||--|||||||||--|--|---|----|||||||||-||||||||-||---------------- 1 [R] COG0622 Predicted phosphoesterase ----------------|-||-|||---|||-|--||||----|||-||-|||-||||||||||||| 1 [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH) -------------|----||------||||-|||||------|||||--|||-|||---|||||-- 1 [R] COG0627 Predicted esterase -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG0629 Single-stranded DNA-binding protein -----------------||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG0632 Holliday junction resolvasome, DNA-binding subunit ---|---------||||-||-|||--|---------------||||||||||-|||---||||||| 1 [C] COG0633 Ferredoxin ----------------||--||----||||||-|||||||||||||||||||||||---|||||-- 1 [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase ||||||||||-||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1 [C] COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K |||||||||||||||-|||||-----|||||-----------|||-|--|--||||---|||||-- 1 [C] COG0644 Dehydrogenases (flavoproteins) ---|------------|-||-|-----||--------------------|----------|-||-- 1 [R] COG0645 Predicted kinase -----------------|||||----|||||---||||----|||||-||-----|---|||||-- 1 [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain ---|--|||--||||-||--|-----|||--|||||||----|||||--|--------|||||||| 1 [G] COG0647 Predicted sugar phosphatases of the HAD superfamily --|||||||-|||---||||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 ||||-||||-|||----|||-|----|||-----||||----|||-|-||---------|||--|| 1 [C P] COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit |||-----||-|-||-|---||-----||||--|||||----||-||-||--|--|---|||-|-| 1 [R] COG0655 Multimeric flavodoxin WrbA ----------------|||||||||||||-|||||||||||||||||-||||||||||||||||-| 1 [R] COG0658 Predicted membrane metal-binding protein |-||||-----|-||---||-------||||------|----|||||-||-|||||---||||||| 1 [R] COG0661 Predicted unusual protein kinase ----------------||||||--||||||||||||||-|--||||||||||||||||||||||-- 1 [H] COG0669 Phosphopantetheine adenylyltransferase -------------||---||||||-|----|||||||--|--|||||-||||-||||||||||||| 1 [R] COG0670 Integral membrane protein, interacts with FtsH --------|---|||--||||---|---------|||-----||||---|-|-||---|--|--|| 1 [P] COG0672 High-affinity Fe2+/Pb2+ permease ||----||--|------|------------|---|-------|||||-||-||--|---||-|--- 1 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [M] COG0682 Prolipoprotein diacylglyceryltransferase |||-----||---|-------|----||||-------|----|||||-||||---|---||-|--- 1 [H] COG0684 Demethylmenaquinone methyltransferase --|-||||--|||||-||||-|----|---||-|||||----||||||||||||||--||||||-- 1 [E] COG0685 5,10-methylenetetrahydrofolate reductase ||||----||---||-----||||---||||-----||----|||||-|||||||||||||||-|| 1 [I] COG0688 Phosphatidylserine decarboxylase |---|||||||||||||--|||----||||-----|||----|||||-||||||||---||||||| 1 [J] COG0689 RNase PH ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0690 Preprotein translocase subunit SecE ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG0691 tmRNA-binding protein -------------|||----||||-|||||-||||||||||||||||||||||||||||||----- 1 [L] COG0692 Uracil DNA glycosylase ---|----|----||---||--||----------||||----|||||||||||---|||||||||| 1 [O] COG0694 Thioredoxin-like proteins and domains --||-----------|--||----------|---|||||||||||||-||------||||------ 1 [G] COG0696 Phosphoglyceromutase -------------|||--||-|-----||-----|-||----|||----|-----||||------- 1 [R] COG0699 Predicted GTPases (dynamin-related) ------------------|-----------|-----||----|||-|-||-----|---------- 1 [S] COG0700 Uncharacterized membrane protein --|----------||-||||||||--||||||||||||----||||||||||||||||||||||-- 1 [E] COG0703 Shikimate kinase |||||||||||||---||||-|---|||||||||||-||-|||||||-||--|--|---|||||-- 1 [P] COG0704 Phosphate uptake regulator -||||-|||||||||-||||-|--|-||||||||||||----|||||-|||||--|--||||||-- 1 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) -------------||-|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [U] COG0706 Preprotein translocase subunit YidC --|------|-|----||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase -|-------|||----|-------------------------|||||--|||------|-|----- 1 [E] COG0709 Selenophosphate synthase --|-------------|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0711 F0F1-type ATP synthase, subunit b -------------||-|||||-----|||||||||||||||||||||||||||||||||||||||| 1 [C] COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) --||||------|---|-||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) |||-----||---||---|||---|-----||||-||-----|||||||||||--||||------- 1 [C] COG0716 Flavodoxins |||||||||||||---|-||--||--|||||------|----||||||-||||||||||||||||| 1 [F] COG0717 Deoxycytidine deaminase -----------------|||||||-||||||||||||||||||||||||||||||||||||||||| 1 [S] COG0718 Uncharacterized protein conserved in bacteria ||||||||||||----||||----------|---|-||----|||||-|||||||||||||||||| 1 [H] COG0720 6-pyruvoyl-tetrahydropterin synthase ||||----||-||---||||||||||||||||||||||--||-------|---||||||||||||| 1 [J] COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit --||||----|||||-|-||-|----|||||-----||----------||--|||||||||||||| 1 [C] COG0723 Rieske Fe-S protein |||||||||||||---|-||-|----|||-|---||||----|||||-||||---|||||||||-- 1 [P] COG0725 ABC-type molybdate transport system, periplasmic component ||||-|-||----------|-------||--|||||--|||||||-|-|||||---|||-||-|-| 1 [V] COG0732 Restriction endonuclease S subunits -----------------|||||||||||||||||||||-|--|||||||||||||||||||||||| 1 [L] COG0742 N6-adenine-specific methylase ----------------|||||||||-|||||----|||----|||||||||||||||||||--|-- 1 [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase |||||||||||||---|-||-|----|||-----||||----|||||-||||--||||||||||-- 1 [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A ------------------||----------------------------||||----|||||-|--- 1 [P] COG0748 Putative heme iron utilization protein -------------|--||||||||||||||||||||||----|||||-|||||||||||||||||| 1 [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains |||||||||||||---||||||||||||||||||||||----|||||-|||||||||||||||||| 1 [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1 ----------------|||||-||-------|||-|||----|||||||||||||||||||||||| 1 [J] COG0751 Glycyl-tRNA synthetase, beta subunit ----------------|||||-||-------|||-|||----|||||||||||||||||||||||| 1 [J] COG0752 Glycyl-tRNA synthetase, alpha subunit --|-----|-|-|---|-||-|----||||----|-||----|||||-|||||||||||||||||| 1 [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component -------------||||---|-|||-||||||||-||-----||||||-|||||||||-||||||| 1 [F] COG0756 dUTPase ----------------||||||--|||||-|-||||||||--|||||-||||||||||||||||-| 1 [L U] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake ----------------||||||||||-||-||||||||----|---|-|||||||||||||||||- 1 [S] COG0759 Uncharacterized conserved protein ----------------|||||||||-|||||-----||----||||||||||||||||||||||-- 1 [I M] COG0761 Penicillin tolerance protein -----------------||||-||||||||||||||||----|||||-||||---||||||-||-- 1 [S] COG0762 Predicted integral membrane protein ----------------|-|||-||------------------|||||-|||||||||||||||||| 1 [M] COG0763 Lipid A disaccharide synthetase ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase |--------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase |||------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase |--------|------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase ----------------|-|||-||------------------|||||-|||||||||||||||||| 1 [M] COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase --|--------------|--|||||||||-||||||||||--||||||||||-|||||||||||-- 1 [F] COG0775 Nucleoside phosphorylase ----------------||||||--|||||-||||||||----|||||-|||||||||||||||||| 1 [S] COG0779 Uncharacterized protein conserved in bacteria ----------|-|---||||-------------||-||----|||||-|||||||||||||||||| 1 [R] COG0780 Enzyme related to GTP cyclohydrolase I ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [K] COG0781 Transcription termination factor ---|--------------||||--|||----|||||||-|--|||||-|||||--|||||-|-||| 1 [P] COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) ------------------|-|-----|-------|-------|||||-|||--||-||-------- 1 [E] COG0786 Na+/glutamate symporter ----------------||||||--|-|||||-----------|||||-||||||||||||||||-- 1 [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase |||---|||||||---|---|-||------|---|||-----|||||-|||||||||||||||||| 1 [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation ----------------|-||||--||||||||||||||----||||||||||-|||||||||||-- 1 [M] COG0796 Glutamate racemase ----------------||||-|||||||||-|||||||----|||||-|||||||||||||||||| 1 [S] COG0799 Uncharacterized homolog of plant Iojap protein ----------------||||||||||||||||||||||-|--|||||-|||||||||||||||||| 1 [R] COG0802 Predicted ATPase or kinase --------------|---||-|----|||-----|-|||----|||---||----|||-||||--- 1 [E] COG0804 Urea amidohydrolase (urease) alpha subunit --||||--|-|||---|-||-|----||||----||||----|||||-|||||||||||||||||| 1 [U] COG0805 Sec-independent protein secretion pathway component TatC ----------------||||||--||||||||||||||----|||||||||||||||||||||||| 1 [J] COG0806 RimM protein, required for 16S rRNA processing ----------------||||||---|----||||||||----|||||||||||||||||||||||| 1 [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [M] COG0812 UDP-N-acetylmuramate dehydrogenase ----------------||||-|||||||||------------|||||-||||-||||||||||||| 1 [M] COG0815 Apolipoprotein N-acyltransferase ----------------||||||||--|||||||-|||||||||||||||||||||||||||||||| 1 [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) -----------------||||||||-||||------------|||||-|||||||||||||||||| 1 [L] COG0817 Holliday junction resolvasome, endonuclease subunit -----------------|||-|--------||||||||----|||||-|||||||||||||||--- 1 [M] COG0818 Diacylglycerol kinase ----------------|||||||||-|||||-----||----||||||||||||||||||||||-- 1 [I] COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis --||----|----|||||-||-||||||||||||||||||||||||||||||-||||||||||||| 1 [C] COG0822 NifU homolog involved in Fe-S cluster formation ----------------|-||||||--|||-||||||||----|||||-||||||||||||||||-- 1 [I] COG0825 Acetyl-CoA carboxylase alpha subunit ----------------|-||--||||----|||||||||-|||||||||||||||||||||||||| 1 [J] COG0828 Ribosomal protein S21 --------------|---||-|----|-------|--||----||----||----|||-||||--- 1 [O] COG0829 Urease accessory protein UreH --------------|---||-|----|||-----|--||----|||---||----|||-||||--- 1 [O] COG0830 Urease accessory protein UreF --------------|---||-|----|||-----|-|||----|||---||----|||-||||--- 1 [E] COG0831 Urea amidohydrolase (urease) gamma subunit --------------|---||-|----|||-----|-|||----|||---||----|||--|||--- 1 [E] COG0832 Urea amidohydrolase (urease) beta subunit ------------------||----------------------|||||--|--||||||-|||||-- 1 [G] COG0837 Glucokinase --||||--|--||---|-||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J) ---------|------||--||--||----||||||||----|||||||||||||||||||||||| 1 [D] COG0849 Actin-like ATPase involved in cell division ----------------||||||--------|----|||----||||||||-|||||||-||||--- 1 [D] COG0850 Septum formation inhibitor ------------------||||--------------------||||||||--||||||-||||--- 1 [D] COG0851 Septum formation topological specificity factor --|||||||-|||---||||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit ----------------||||-|----|||||---||||----|||||--|--||||||||--||-- 1 [H] COG0853 Aspartate 1-decarboxylase ----------------|-||----------------------|||||-||--||||||||||||-- 1 [H] COG0854 Pyridoxal phosphate biosynthesis protein --|---------------||-|-----||||------|----|||||-||--||||||||||||-- 1 [P] COG0855 Polyphosphate kinase ---|----|---------||-|-----||-------------||||||||||-||-|||------- 1 [R] COG0857 BioD-like N-terminal domain of phosphotransacetylase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [J] COG0858 Ribosome-binding factor A --||||--|-|||---|-||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H) ||||--||---------|||-|----|-------||||----------||---------|||--|| 1 [P] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit --||||--|-|||---|-||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N) --||||----------|-||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M) ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG1010 Precorrin-3B methylase -------------||-|----|----|-------|-||----|||||-||--|--|--|-|----- 1 [C] COG1017 Hemoglobin-like flavoprotein ---------------------------||-------|-----|||||-||-----------|---- 1 [Q] COG1021 Peptide arylation enzymes ---|----|-|-|||||-|||---||||||---------------|--||||-------------- 1 [I] COG1022 Long-chain acyl-CoA synthetases (AMP-forming) -------------|||------||------------------|||||-||---------------- 1 [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like ----||-----------|-|------|---|-----||----|||||-||||-||-||||-|---- 1 [E] COG1027 Aspartate ammonia-lyase --|-|||||-|-|---|-----------------|-||-----------|-----|----|-|--- 1 [O] COG1030 Membrane-bound serine protease (ClpP class) -|||--||||-------|------||-----------|-----------|--------|------- 1 [R] COG1033 Predicted exporters of the RND superfamily ----------------||||-|-----||-|-----------||||||-|--|||||||||||||| 1 [C] COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) ----------------||||||--||-||-||||||||----|||||-||||||||||||||||-| 1 [R] COG1040 Predicted amidophosphoribosyltransferases ----------------|-|||-||------------------|||||-|||||||||||||||||| 1 [M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase ----------------|-|||-||------------------|||||-|||||||||||||||||| 1 [M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase ------------------||----------------------|||||-||-|||||||||------ 1 [C] COG1049 Aconitase B ------------------||-|||--|----||||||-----||||||||--|--|---||||||| 1 [R] COG1054 Predicted sulfurtransferase ----|||||-|||----||||-||---|||----||||----||||--||---|||--||--|--- 1 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases -----------|-||---||------||||-------|----|||||--||--|||---|||||-- 1 [C] COG1062 Zn-dependent alcohol dehydrogenases, class III ----------------|||||||||-|||-|||-||||----|||||-|||||||||||||||||| 1 [O] COG1066 Predicted ATP-dependent serine protease ||||||||||-------|------|-----|-----||----|||||-||||-------------- 1 [O] COG1067 Predicted ATP-dependent protease --------------------|-||||-||-||||||||----|||||||||||||||||||||||| 1 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) |---||--||------||-||-||||----|----|||----|||||-|||||--||||----||| 1 [D] COG1077 Actin-like ATPase involved in cell morphogenesis ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG1079 Uncharacterized ABC-type transport system, permease component -|---------------|--|---|-|---|--||-||----------||-||||||||-|||||| 1 [M G] COG1086 Predicted nucleoside-diphosphate sugar epimerases |------------||-|-||||----|---||-|-|||--|||||||-||||-|||||||||||-- 1 [M] COG1087 UDP-glucose 4-epimerase |-|--||||--||-|---||||----|||||||---||----|||||--|||||||---||-||-- 1 [M] COG1088 dTDP-D-glucose 4,6-dehydratase |-|-----|-------|-||-------||-|-----------|||-|-||--|---||-|-|||-- 1 [M] COG1089 GDP-D-mannose dehydratase ----||------------||------||||----||||----|||||--||||------------- 1 [R] COG1090 Predicted nucleoside-diphosphate sugar epimerase --------------------|-----|-----||--------------||-----|---||||-|| 1 [R] COG1101 ABC-type uncharacterized transport system, ATPase component -----------------|--||---||||-||||||||--|||||||-||||---|---------- 1 [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) ||||---||||||---||||-|---||||||||||||||-|||||||-|||||--|--||||||-- 1 [P] COG1117 ABC-type phosphate transport system, ATPase component ------------------||-------||--------|----|||||-||--||||||||||||-- 1 [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component --------|----------|||-----||-|||||||-----|||||--|------||-||||--- 1 [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components -----------------|--|---|||----|----||-|--|||||-||||---|---|||||-- 1 [G] COG1129 ABC-type sugar transport system, ATPase component ----------------||||||||||----------------|||||-|||||||||||||||||| 1 [R] COG1137 ABC-type (unclassified) transport system, ATPase component --|-----|-|-|--------|--------------------|||||-|||||------||||||| 1 [O] COG1138 Cytochrome c biogenesis factor ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 1 [C] COG1140 Nitrate reductase beta subunit |||||||||-|||---||||-|-----||-------------||||||-|--|||||||||||||| 1 [C] COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) ----------------|||||||||-||||||---|||----||||||||||||||||||||||-- 1 [H I] COG1154 Deoxyxylulose-5-phosphate synthase ----------------||--|||||||||||---||||----|||||||||||||||||||||||| 1 [K] COG1158 Transcription termination factor ----------------||||||--|||||||||||||||||||||||||||||||||||||||||| 1 [R] COG1159 GTPase ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [R] COG1160 Predicted GTPases --|-------------|||||----||||||||||||||||||||||-||||||||------|--- 1 [R] COG1162 Predicted GTPases ------------------||-|--------------------|||||-||-||||-|||------- 1 [E] COG1166 Arginine decarboxylase (spermidine biosynthesis) ---|--------------||------||||-|--|||-----|||||-||||---------|---- 1 [H Q] COG1169 Isochorismate synthase -----------------|--|-----|--|-|----||----|||||-||||---|---|||||-- 1 [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components --|||||||-|||---||||||||-||||||||||||||||||||||-||||---||-|||||--- 1 [E P] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components -------------||-----|---------|---|-||----|||||-|||||||||||------- 1 [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 |||-|||||||||---||--|------||-||||||------|||||-||||---|---------- 1 [O] COG1180 Pyruvate-formate lyase-activating enzyme -------------||-||||||||||||||||||||||----|||||||||||||||||||||||| 1 [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) -----------------|--|-----|---||||||||----|||||-||||-|||||||||||-- 1 [J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) --|-------||-|||||||||||--|||||||||||||||||||||||||||||||||||----- 1 [J] COG1190 Lysyl-tRNA synthetase (class II) ----------------||||--|||--||-|---||||----|||||-||-----||||------- 1 [K] COG1191 DNA-directed RNA polymerase specialized sigma subunit |--|------|-|-|------||||-||||||||||||----||||||||||||||||||||||-- 1 [L] COG1194 A/G-specific DNA glycosylase ----------|-------|||||-|-||||||||||||----|||||-|||||------||||||| 1 [L] COG1195 Recombinational DNA repair ATPase (RecF pathway) -||||||||----|||||||||--||||||||||||||||||-------|--|||----|||||-- 1 [D] COG1196 Chromosome segregation ATPases -----------------|||||||||||||||||||||----|||||||||||||||||||||||| 1 [L K] COG1197 Transcription-repair coupling factor (superfamily II helicase) ----------------||||||||||||||||||||||----|||||||||||||||||||||||| 1 [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase ----------------||||||--||||||||||||||----|||||-|||||||||||||||||| 1 [L K] COG1200 RecG-like helicase |||||||||||||------|------|||-------------|||----|-----|---|||||-- 1 [R] COG1201 Lhr-like helicases ----------------||||||----||||||||||||----|||||||||||||||||||||||| 1 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) |||||||||||||||||-||-|----|||||-----||-------||--|--||||--||||||-- 1 [M J] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) |-|||||||--||----|||-|----|||||||---||----|||||--|--||||---||-||-- 1 [M] COG1209 dTDP-glucose pyrophosphorylase |||----|---|----|--||----|||||||||||||--|||||||-||||||||||||||||-- 1 [M] COG1210 UDP-glucose pyrophosphorylase ------|---------|||||||||-|||||--|||||--||||||||||||||||||||||||-- 1 [I] COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase ----------------|---|-||------------------|||||-|||||||||||||||||| 1 [M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase |-----|||---|---|---|----------------------------|--------|----|-- 1 [M] COG1213 Predicted sugar nucleotidyltransferases ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone |-|--||||---|-----||-|----|||||-----------|---|--||-|--|---||-||-- 1 [R] COG1216 Predicted glycosyltransferases ------------------||||----||||||||||||----|||||||||||||||||||||||| 1 [T] COG1217 Predicted membrane GTPase involved in stress response -------------||-|-||--||--||||------------|||||||||||-----|||||||| 1 [P] COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase -------------|--||||||||||||||||||||||----|||||||||||||||||||||||| 1 [O] COG1219 ATP-dependent protease Clp, ATPase subunit ----------------||-------|--------||||----|||||||||||--||||||||||| 1 [O] COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit --||||----|||||-||||-|----|||||---|-||----|||||-||||||||||||||||-| 1 [O] COG1225 Peroxiredoxin |--||||-|--|-|---|--||-----||-|-|-|-||-------||-||-----|---|||||-- 1 [Q] COG1228 Imidazolonepropionase and related amidohydrolases ------------------||-|----|||-------|------------|-----|------||-- 1 [E] COG1231 Monoamine oxidase -||||||-|-||||||--||-|--------------------------||-----|---||-||-- 1 [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing ||||||--||--------||-|----|||--------------------|-----|---------- 1 [H] COG1239 Mg-chelatase subunit ChlI ||||||---|--------||------|||--------------------|-----|---------- 1 [H] COG1240 Mg-chelatase subunit ChlD --||------------|----|-----|||------||----||||||||-|-|||---------- 1 [E] COG1246 N-acetylglutamate synthase and related acetyltransferases --|-------|-|-----||-|----|---||-|||||----|||-|-||-----|---|||||-- 1 [M] COG1247 Sortase and related acyltransferases -||-|||||-|||----|-|-|---|--|-||||||||----|||||-||-|---|----|-|--- 1 [C] COG1254 Acylphosphatases ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1256 Flagellar hook-associated protein ----------------||------------------------||||||||-----|||||||||-- 1 [N O] COG1261 Flagellar basal body P-ring biosynthesis protein --------------------|----||---||||||||-|||||||||||-|---|-------|-- 1 [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific --------------------|----||---||||||||||||||||||||-|---|-------|-- 1 [G] COG1264 Phosphotransferase system IIB components |||---||-||-|---|---|-----------|--|||----|||||-||||-||||||-----|| 1 [I] COG1267 Phosphatidylglycerophosphatase A and related proteins |||||||||||||-----||||-----||-|----|-|--------|-||-----|---||||--- 1 [H] COG1270 Cobalamin biosynthesis protein CobD/CbiB --||||--|-------|-||--||--|||--|--||||----|||||-||||---|--|||||||| 1 [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1 -------------|||----||--|||||-||||||||----|||||-||--|||----|||||-- 1 [R] COG1272 Predicted membrane protein, hemolysin III homolog --------|------------------||-------||-----------|---------||-|--- 1 [S] COG1273 Uncharacterized conserved protein --------------------|-----|||-|---|-||----|||||-||-|---|||-|-|---| 1 [R] COG1279 Lysine efflux permease ----------------||||||--------||||||||-|--|||||-||||||||---|||||-- 1 [O] COG1281 Disulfide bond chaperones of the HSP33 family ------------------||-------|||------------|||||-||||-|||---||||||| 1 [C] COG1282 NAD/NADP transhydrogenase beta subunit ------------------------||-----|||||||----|||||-|||||||||||||||||| 1 [R] COG1286 Uncharacterized membrane protein, required for colicin V production ---|||----||||--|-||-|----||||------||----------||--|||||||||||||| 1 [C] COG1290 Cytochrome b subunit of the bc complex --||------------|-||--||--|||--|--||||----|||||-||||---|--|||||||| 1 [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2 --|-----|-----------||----|----|-|||||----|||||-||||-|||||-||||--- 1 [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance) ---|--|------|-------------||--------------------||-||||--|----|-- 1 [S] COG1297 Predicted membrane protein ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1298 Flagellar biosynthesis pathway, component FlhA --------------------||---||---||||||||-||||||||-|||----|---------- 1 [G] COG1299 Phosphotransferase system, fructose-specific IIC component |||---||||--|-----||-------||-|---|-||-----------|------------||-- 1 [S] COG1300 Uncharacterized membrane protein -----------------|--||----|||-||||||||||||-------|---------------- 1 [S] COG1307 Uncharacterized protein conserved in bacteria ----------------|-|||||||||||||||||||||-|-|||||||||||||||||||||||| 1 [U] COG1314 Preprotein translocase subunit SecG ----------|||--------|--||-||-------||----|||----|-----|---||-|--- 1 [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs ||||--||---------|---|----|-------||||----------||---------|||--|| 1 [P] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit ----------------------||-------|||-----|--|||||-||||||||---||||||| 1 [S] COG1322 Uncharacterized protein conserved in bacteria -----------------||-||||--||||||||||||----|||||-||||||||---|||||-- 1 [K] COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains |||---||-|-------|--|---------||||||------|||||-||||---|---------- 1 [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase ----------------------||-|-||-------------|||||||||||||----------- 1 [L] COG1330 Exonuclease V gamma subunit ----------------||------------|-----||----------||------|||------- 1 [N] COG1334 Uncharacterized flagellar protein FlaG ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1338 Flagellar biosynthesis pathway, component FliP ----------------||------||----|----|||----|||||-||-----||||------- 1 [N] COG1345 Flagellar capping protein ----------------------||---------------------|--||||-||----------- 1 [C] COG1347 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD -||||||||-------||||||--|-||||||||||||||||-------|--||||---|||||-- 1 [S] COG1354 Uncharacterized conserved protein -------------||--|--|----||||||------------------|---------------- 1 [E] COG1362 Aspartyl aminopeptidase |||-----||---||-||||-|----||||||--||||-----------|---|||---|||||-- 1 [E] COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase) ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1377 Flagellar biosynthesis pathway, component FlhB ------------------|||||||-||||||||||||||--|||||-||||||||---||||||| 1 [L] COG1381 Recombinational DNA repair protein (RecF pathway) --|-|||||--------|||||--|-||||||||||||||||-------|--||||---|||||-- 1 [K] COG1386 Predicted transcriptional regulator containing the HTH domain ----------------|----|||-||||-||--||||-------|--||||-------------- 1 [M] COG1388 FOG: LysM repeat ----------------|---------||||------------|||||-||||-|||---|||||-- 1 [O T] COG1391 Glutamine synthetase adenylyltransferase |||---|||--|-----|---|||------|---|||-----------||||---|---||-|--- 1 [P] COG1392 Phosphate transport regulator (distant homolog of PhoU) -------------||---||-----------------------------|-----|--------|| 1 [I] COG1398 Fatty-acid desaturase ----------------||||-|----||||||||||||----|||||-||||||||---------- 1 [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein |-|---|||||-|||-|-||--||--||||||--|||-----|||||-||||---|---|||||-- 1 [R] COG1409 Predicted phosphohydrolases -----------------|||-|----|||||------|----|||||-|||-|--|---|||||-- 1 [E] COG1410 Methionine synthase I, cobalamin-binding domain |-||---------|||--||--||||--------|-||----||-----|------------|--- 1 [C] COG1413 FOG: HEAT repeat ----------------||------||----|----|||----------||-----||||------- 1 [N] COG1419 Flagellar GTP-binding protein -----------------|-|--||||-----|||||||----|||||-|||||--|--------|| 1 [S] COG1426 Uncharacterized protein conserved in bacteria ||||--||||------|-||-|--|-|---------------------||----|-||||||||-- 1 [S] COG1432 Uncharacterized conserved protein --------------------||---||---||||||||-||||||||-||||---|---------- 1 [G] COG1445 Phosphotransferase system fructose-specific component IIB ||||--|||-------|---||----|---|-------||--|||||-||--||||||||||||-| 1 [R] COG1451 Predicted metal-dependent hydrolase ----------------|-------||----------------|||||-|||||||||||||||||| 1 [M] COG1452 Organic solvent tolerance protein OstA ----------------|-||-|--------------------|||||--|---|||-------|-- 1 [M] COG1462 Uncharacterized protein involved in formation of curli polymers ----------------||||-||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG1466 DNA polymerase III, delta subunit ||||||||||--|----|----------------|-||-----------|--||||---------- 1 [S] COG1469 Uncharacterized conserved protein ||||---||----------|-|--------||||||||-----------|-------------|-- 1 [K] COG1476 Predicted transcriptional regulators --|-------------||--|||||-----||||-|------|||||-||||||||----||||-- 1 [H] COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis |---||--|-|||---||||----------|------|----|||||-||||-------|||-|-- 1 [R] COG1489 DNA-binding protein, stimulates sugar fermentation -------------||-||--||----|||-||||||||----|||||-||||-|||---------- 1 [J] COG1490 D-Tyr-tRNAtyr deacylase ||||||--||-|------||||-----||-|----|-|--------|-||-----|---|||||-- 1 [H] COG1492 Cobyric acid synthase ---|||||--|||||---|-||------------|-||-----------|--|------|---|-| 1 [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases ----------------|-----||||----|----|||----|||||-||--||||||||||||-- 1 [K] COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog ----------------|-||----------------------|||----|-----|---------- 1 [P] COG1513 Cyanate lyase |||-|||||||||---||-|-|----|---|---|-||----|||||--|-----|---|||||-- 1 [J] COG1514 2'-5' RNA ligase ----------------||------||----|----|||----|||||-||-----||||------- 1 [N U O] COG1516 Flagellin-specific chaperone FliS ----------------|---|-||------------------|||||-|||||||||||||||||| 1 [M] COG1519 3-deoxy-D-manno-octulosonic-acid transferase ||||--|||--------|---|---|-|||------|-----|||||-||--|--|-------||| 1 [S] COG1520 FOG: WD40-like repeat ----------------||||||--||-||||----|||-|---------|--|||||||----|-- 1 [K] COG1521 Putative transcriptional regulator, homolog of Bvg accessory factor --|--------|-----||-||||--|||-|-||--||-|--|||||-||||---|---||-|--- 1 [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases ----|||||--|-|||-|-|------|---|----|-|-----------|--|-----|-|-||-- 1 [R] COG1524 Uncharacterized proteins of the AP superfamily ||-|--||-|---||-|--|------|-------|-|--|||-------|||-||---|||||--- 1 [L] COG1525 Micrococcal nuclease (thermonuclease) homologs |||-||--|-||--------------|||-----||||----|||||-||||---|--||||||-- 1 [C] COG1526 Uncharacterized protein required for formate dehydrogenase activity -||-|-|||||||----||-|------||-|-----||-----------|-----|---|||||-| 1 [L] COG1533 DNA repair photolyase ||||--||||-||-------|---------||||||||----|||||-||||||||---------- 1 [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein ----------------||----||||----|----|||----||||||||-----|||||||||-- 1 [N] COG1536 Flagellar motor switch protein ----------------||||||-|-|||||||||||||----|||||-|||||--|---||||||| 1 [J] COG1544 Ribosome-associated protein Y (PSrp-1) -----------------|------||----|-----||----|||||||||||---|||------- 1 [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing) |||------|-------|------------------------||||||||||-------------- 1 [P] COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction --|--------------|||||----|||-||||||||----|||||-||||||||--|------- 1 [L] COG1555 DNA uptake protein and related DNA-binding proteins ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1558 Flagellar basal body rod protein ----------------|---||--||||||||||-|||----|||||-|||||||||||||||||| 1 [R] COG1559 Predicted periplasmic solute-binding protein ----------------||--|----|----|----|||----|||||-||||||||---|||||-- 1 [S] COG1561 Uncharacterized stress-induced protein -----------------|-|||||--||||||||||||----|||||-|||||||||||||||||| 1 [L] COG1570 Exonuclease VII, large subunit -----------------|--||--------||||||||||--|||||-||||||||||||||||-- 1 [S] COG1576 Uncharacterized conserved protein ||-|--||-||||----|||||----|||||-----------|||||-||-||------|||||-- 1 [O U] COG1585 Membrane protein implicated in regulation of membrane protease activity ||||||--||||-||-|-||||||--|||||---||||----|||||-||-||||||||||||--- 1 [H] COG1587 Uroporphyrinogen-III synthase ------------------||-|--||||||||||||||----|||||-||||||||---||||||| 1 [M] COG1589 Cell division septal protein ----------------||||----------------------|||-|-||-|||||--||||||-- 1 [M] COG1596 Periplasmic protein involved in polysaccharide export ----|--------||--|||-|----|||-||||||||----|||||--|---------||-||-- 1 [I R] COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase |-|-----|---------||-|--------|-|-||||----|||||-||-----|---|||||-- 1 [C] COG1600 Uncharacterized Fe-S protein -------------|---|--------|||-|----|||----------||--||||--|||||--- 1 [S] COG1610 Uncharacterized conserved protein ---|--------|||-|-||-|----||||----||||-----------|--|--|---||||||| 1 [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly ----||------------||||--|-----||-|-|||-|--|||-|-||---|||--------|| 1 [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF ---|----||-|---------|---|--------|-||----|||-|-||||-||||||--|---- 1 [C] COG1620 L-lactate permease -------------|||---|----||----------------|||-|--|-----|---------- 1 [G] COG1626 Neutral trehalase ----------|-----|-||||||-||||--|||--------|||||-||||---|---------- 1 [G] COG1640 4-alpha-glucanotransferase ||||||--|||-|||-|---|------||-|---||||----||||||||--|||----|||||-- 1 [H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) --||---||------------|--------||||||||----|||||-|||||------------- 1 [K] COG1654 Biotin operon repressor --------------------||----||||||||||||----|||||-||||||||---------- 1 [R] COG1660 Predicted P-loop-containing kinase ----------------|---|-||------------------|||||-|||||||||||||||||| 1 [M] COG1663 Tetraacyldisaccharide-1-P 4'-kinase ----------------------||||----|-----|--------|--||--|--||||----|-- 1 [M] COG1664 Integral membrane protein CcmA involved in cell shape determination -------------------|-------||-------||----|||||-||||---|--|------- 1 [S] COG1666 Uncharacterized protein conserved in bacteria ------------------------||----|---||||----|||||-||---------|||||-- 1 [S] COG1671 Uncharacterized protein conserved in bacteria -------------------|-||||||||||||||||||---|||||-|||||||||||||||||| 1 [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1677 Flagellar hook-basal body protein ---------------------|||--||||------------|||||-||||||||---||||||| 1 [K] COG1678 Putative transcriptional regulator |||---|||||-|------------------------------------|---------||-|--- 1 [S] COG1679 Uncharacterized conserved protein ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1684 Flagellar biosynthesis pathway, component FliR -------------||----||---|-----|||||||------------|---||-|-|-|----- 1 [M] COG1696 Predicted membrane protein involved in D-alanine export ---------||-|---||||-|----||||-|||||||----|||||-||-|||||---|||||-- 1 [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase -----------------|-------------||-|||-----|||||-||-----|-----|---- 1 [N U] COG1705 Muramidase (flagellum-specific) ----------------||-------|----------------||||||||-----|||||||||-- 1 [N] COG1706 Flagellar basal-body P-ring protein |||-----|||------|-------------------------------|-----|---------- 1 [R] COG1712 Predicted dinucleotide-utilizing enzyme ||||||||||||||||-----|-----------------------|---|---------------- 1 [T D] COG1718 Serine/threonine protein kinase involved in cell cycle control ||||--|||||||----|------------------------|||||-||||-||-------||-- 1 [S] COG1720 Uncharacterized conserved protein -----------------|-|||----||||||||||||----|||||-|||||||||||||||||| 1 [L] COG1722 Exonuclease VII small subunit ----------------------||---------------------|--||||-||----------- 1 [C] COG1726 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA ----------------|-------------------------|||||-||--||||---||||||| 1 [S] COG1729 Uncharacterized protein conserved in bacteria ---|----|----------|||-----||-|||||||-----|||-|--|-----|||-||||--- 1 [M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) --||----|-|-|----|--||||-||-------|-|-----|||||-||||-||----||||--- 1 [S] COG1738 Uncharacterized conserved protein --||---------||--|--||---||---||||||||||--|||-|-||||-|||||||||---- 1 [S] COG1739 Uncharacterized conserved protein --|---------------|--------||-----|-||----|||-|--|-----|---||-||-- 1 [S] COG1742 Uncharacterized conserved protein ---|--|||-|-|----|-|-|--||----||||-|||||||-------|-----|---||||--- 1 [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein ----------------|-------||----|----|------||||||||-----|||||||||-- 1 [N] COG1749 Flagellar hook protein FlgE ||||||||||||||||||||-|--||||||||||||||----|||||-|||||||||||||||||| 1 [K] COG1758 DNA-directed RNA polymerase, subunit K/omega --------------------|-|||||---||||||||-||||||||-||||-|||---|||||-- 1 [G T] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein |||---||||-||-------|-----------|---------|||-|-|||--------------- 1 [H] COG1767 Triphosphoribosyl-dephospho-CoA synthetase -------------------|------||||---|--------|||||-||--|------||||||| 1 [E] COG1770 Protease II --|-------------|---|---------------------|||||-|||||||||||------- 1 [R] COG1778 Low specificity phosphatase (HAD superfamily) --||---|-----||--|-|-|----|-------|-||----||||---|--|--|-----|---- 1 [P] COG1785 Alkaline phosphatase |||---|||||-|------------------------------------|---------||-|--- 1 [S] COG1786 Uncharacterized conserved protein -------------||-|--|----------------|------------|--|------------- 1 [S] COG1791 Uncharacterized conserved protein, contains double-stranded beta-helix domain ----------------|--||-||||----||-|||||----|||||-|||||--||||----||| 1 [M] COG1792 Cell shape-determining protein |||||||||||||||||----------||-------||----------|||--||---|||-||-- 1 [L] COG1793 ATP-dependent DNA ligase ||||||--||||------||||-----||-|----|-|--------|--|-----|---||||--- 1 [H] COG1797 Cobyrinic acid a,c-diamide synthase ------------------||--||---------------------|--||||-||-------|--- 1 [C] COG1805 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB ---------------------|------------||||----|||||-||--||||---||||||| 1 [S] COG1806 Uncharacterized protein conserved in bacteria ||--|||||||||||--|---||---|----|-----------------|------------||-- 1 [S] COG1814 Uncharacterized membrane protein ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1815 Flagellar basal body protein -------------||----|----|--|-|||----------|||-|-||-----|---||-||-- 1 [F] COG1816 Adenosine deaminase |||------|---|----|--|-----||||-----|------||||-||------------|--- 1 [G C] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase -----------|-----|-|||---||||-||||||||-|--|||||-|||||------|||||-- 1 [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase ----------------||||-|||||||||----||||----|||||||||||||||||||||||| 1 [J] COG1825 Ribosomal protein L25 (general stress protein Ctc) --|---------|-----||-------||-|-----||-----------|----------|-|--- 1 [E] COG1834 N-Dimethylarginine dimethylaminohydrolase |||---|||||-----||------------|------|----|||||-||--||||-----||--- 1 [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain ||||||||||||||||||--||--||||||||||||||----||||||||||||||----|||||| 1 [J] COG1841 Ribosomal protein L30/L7E --|-------------|-||-|----|||-|----|||----|||||-||------------||-- 1 [K T] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG1843 Flagellar hook capping protein --|-|||||||-|||-----||--------------------|||----|---------|------ 1 [J] COG1859 RNA:NAD 2'-phosphotransferase ----------------||--|-||-|||||||||||||----|||||||||||||||||||||||| 1 [U] COG1862 Preprotein translocase subunit YajC ||||--||---------|---|----|-------||||----------||---------|||--|| 1 [P] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit --|----------||----||----|--------------------|--|-----||||----|-- 1 [F] COG1864 DNA/RNA endonuclease G, NUC1 ------------||------||------------|-||----|||||-||||------|||||--- 1 [C] COG1866 Phosphoenolpyruvate carboxykinase (ATP) ----------------||------||----|----|||----||||||||-----||||||||--- 1 [N] COG1868 Flagellar motor switch protein --||--|||--------|-------|----|-----||----------||-----|---||--|-- 1 [N T] COG1871 Chemotaxis protein; stimulates methylation of MCP proteins -----------------|----||--||||------||----------||--|--|---------- 1 [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH ||||||-||-||-----|||------|||-----|--|-----------|||---|---||-|--- 1 [R] COG1878 Predicted metal-dependent hydrolase --|--------------|--|---|-|--|||----||----|||||-||||---|---|||||-- 1 [G] COG1879 ABC-type sugar transport system, periplasmic component |-----|------------------------|--|||------------|--|------------- 1 [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC |-------------|-||||-|-----||-------------||||||-|--||||---||||||| 1 [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit ---|--|||||||||------|------------||------|||||-||-|----||||||||-- 1 [R] COG1896 Predicted hydrolases of HD superfamily |-|--||||--||-----||||----|||||||||-||----|---|--|-|||||--||||||-- 1 [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes |||-||--||||------|||---------|----|----------|--|-----|---|-|---- 1 [H] COG1903 Cobalamin biosynthesis protein CbiD |-------------|-||||-|-----||-------------||||||-|--||||---||||||| 1 [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit |||----|||-------||--|--------||--||------|||||-||--|--|-||----|-- 1 [P] COG1918 Fe2+ transport system protein A ||--|----|------|-------------------------|||||--|||----|||||-|--- 1 [E] COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase] -|--------------||------------|---||||----|||||-||||||||----||||-- 1 [R] COG1923 Uncharacterized host factor I protein ------------------|-------|||-||||||||----|||||-||||-||----------- 1 [G] COG1929 Glycerate kinase --|----------||----|------||||-|---|||----||||||||||||||--||||||-- 1 [H E] COG1932 Phosphoserine aminotransferase ----------------|-||----------------------|||||-||||||||||||||||-- 1 [S] COG1934 Uncharacterized protein conserved in bacteria ------------------||-|----||||||--||||----|||-|--|-----|--|||----- 1 [S] COG1937 Uncharacterized protein conserved in bacteria --||||-----|-----|-|||------|-|--|---|----|||||-|||--|||||----||-- 1 [L] COG1943 Transposase and inactivated derivatives ||||-----|-----------------||-------------|||||--|||-------||-|--- 1 [S] COG1944 Uncharacterized conserved protein ----------------|||||||-|-|||||---|||||---||||||||||||||||||||||-- 1 [I] COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase -------------||-----------||||------------||||||||||||||---------- 1 [A] COG1949 Oligoribonuclease (3'->5' exoribonuclease) |||---|||||-----||------------|------|----|||||-||--||||-----||--- 1 [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain -|----------------------------------------||||||||||||||---||||||| 1 [U] COG1952 Preprotein translocase subunit SecB ---|||-------|---|------------||||||||----|||||-||-||||-------||-- 1 [T] COG1956 GAF domain-containing protein -----------|-||----|-|----|||-----|--|----|||-|--|-|---|--||||||-- 1 [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase -----||---|-------||-|----|||-|-||||||----|||||-||--|--|---|||||-- 1 [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs -------------|||--------------------------||||||||||-|||--------|| 1 [P] COG1965 Protein implicated in iron transport, frataxin homolog --|----|--|-|---|---|-----|||-||----||----|||||-||||-||||||------- 1 [T] COG1966 Carbon starvation protein, predicted membrane protein |--------|||----||||||---||||||||||-||----||||||||--||||--||||||-- 1 [V] COG1968 Uncharacterized bacitracin resistance protein --|---------------|-||----||||-||||||-----|||||-|||||--|---|||||-- 1 [M] COG1970 Large-conductance mechanosensitive channel |-|-----------------|-----|---|-----||----|||||--|--|||---|------- 1 [S] COG1971 Predicted membrane protein -----------------|||-|----||||||--||||----|||||-|||||--|---|||||-- 1 [K T] COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases) --||||-||-||----|-||-|-----||-----||||----|||||-||||---|||||||||-- 1 [H] COG1977 Molybdopterin converting factor, small subunit ------------------||-----------------------------|--|||||||||||||| 1 [S] COG1981 Predicted membrane protein ||||----|||||||-||||||||--||||||-||-||----||||||||||||||||||||||-- 1 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N U] COG1987 Flagellar biosynthesis pathway, component FliQ |||---||||--|-----------------|---||||----|||||--|-|-------------- 1 [R] COG1988 Predicted membrane-bound metal-dependent hydrolases ||||--||||------||||-|----|||-||||||||----|||||-||||||||--|---||-- 1 [N O U] COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases ---|------|-|||-|----|--------------||----------||--||||--|||||||| 1 [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems ---------------------|--|-|||||---|||||||||||||--|||||||----|--||| 1 [S] COG2001 Uncharacterized protein conserved in bacteria --|-------------|||||---------||||||||----|||||-||||||||---||||--| 1 [L] COG2003 DNA repair proteins |-|-----||||------------------------------|||||--|||---|--|||-||-- 1 [R] COG2005 N-terminal domain of molybdenum-binding protein ---|||--|-|-|||------|||---|||----|-||----|||||-||--|||||||||||||| 1 [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit |-||||-|||-||----||--|--------|||----------------|------------||-- 1 [S] COG2013 Uncharacterized conserved protein -------------|-------------||-------------|||---||-------------|-- 1 [Q] COG2015 Alkyl sulfatase and related hydrolases |-||---------||------|----||||----||-------------|||||||------||-- 1 [E] COG2021 Homoserine acetyltransferase ----------------|-||||----|||||-----||----|||||-||--||||--||||||-- 1 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis --|---------------||-|----||||------|-----|||||-||||||||---------- 1 [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) --------|---|-------|-----|-----|----|----|------||-----||-------- 1 [I] COG2031 Short chain fatty acids transporter |||||||||||||-----||||----|||||------|----|||-|-||-----|---|||||-- 1 [H] COG2038 NaMN:DMB phosphoribosyltransferase ||------||||----|--------------------------------|---------------- 1 [R] COG2044 Predicted peroxiredoxins ||----||-|----------------|---|-----|-----|||-|--|||-------||||--- 1 [C] COG2055 Malate/L-lactate dehydrogenases --------------------|-------------|-||----------||||-||-|||------- 1 [R] COG2056 Predicted permease -|---------------|||||---||---------||-|--------||-----|---||-||-- 1 [P] COG2059 Chromate transport protein ChrA ---|||------------||-|-----||-|---||------|||||--|-----|---||-||-- 1 [P] COG2060 K+-transporting ATPase, A chain --------|-|||---|-||------||||------------|||||-|||||--|--||||||-- 1 [T] COG2062 Phosphohistidine phosphatase SixA ----------------||------------------------||||||||-----|||||||||-- 1 [N] COG2063 Flagellar basal body L-ring protein |||||||||||||-------------||--|--------------|---|-|---|---||-||-- 1 [N U] COG2064 Flp pilus assembly protein TadC ------------------||||----|||-||||||||-----------|||---|---------- 1 [F] COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase ------------------|||-----|---------||----|||||-||-----|---|||||-- 1 [E] COG2066 Glutaminase --------------|-----|------|||||||-|------|||----|--------|||||||| 1 [R] COG2071 Predicted glutamine amidotransferases ----------------|---------|||-||-|||||-|--|||||-||||---||||------- 1 [O] COG2077 Peroxiredoxin ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2082 Precorrin isomerase ------------------||||----|||-|----|-|----|||-|-||-----|---||||--- 1 [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase ------------|--|-----|-|-|-||||---|||------------|---------||-|-|| 1 [L] COG2094 3-methyladenine DNA glycosylase ---||||||-|||-------||----||||-----|||--------|--|-----|---|||||-- 1 [S] COG2096 Uncharacterized conserved protein ||----------------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2099 Precorrin-6x reductase |-|||||||-------|-||||----|||||-----||----||--|-||--||||--||-|||-- 1 [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis -||---|---||------||-|--------------||----|||||-||-----|---------- 1 [S] COG2105 Uncharacterized conserved protein --||||||--|------|||||-----||-------------|||||-||-----|---||||--- 1 [H] COG2109 ATP:corrinoid adenosyltransferase ||||--||---------|||-|----|-------||||----------||---------|||--|| 1 [P] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit --|----------|||--||----|-||||-------------------|---------||-||-- 1 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) ---------|---|------|---------|||||||-----|||||-||||-------------- 1 [P] COG2116 Formate/nitrite family of transporters ---|---------||---||-------||-------------------||-----|-------|-- 1 [S] COG2119 Predicted membrane protein ------------------||-|----|||||-----------|||||-||--||||||||||||-- 1 [S] COG2127 Uncharacterized conserved protein ---|---------|-----|------||||------|-----|||-|--|---------||||--- 1 [S] COG2135 Uncharacterized conserved protein -----------------|--||--|-||||||||||||----|||||-||||-|||---|------ 1 [R] COG2137 Uncharacterized protein conserved in bacteria ----||--|---|--------|-----|||------------|||||-||--||||---||||||| 1 [C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit ---|-------------|||||----|---|--||-||----|||-|-||||||||--||||||-- 1 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis --------------|---|-------|||--|-----|----|||-|-||-----------|---- 1 [R] COG2153 Predicted acyltransferase ---|------||-||-|-||------||||------------------||--|--|----||||-- 1 [H] COG2154 Pterin-4a-carbinolamine dehydratase ---|||------------||-|-----||-|---||------|||||--|-----|---||-||-- 1 [P] COG2156 K+-transporting ATPase, c chain ---------------------------||-----|-||----|||-|--|------------||-- 1 [Q] COG2162 Arylamine N-acetyltransferase ------------------||-|||---||-------------|||||-|||||------|||||-- 1 [R] COG2166 SufE protein probably involved in Fe-S center assembly |----------------|------------------------||||||||||-------------- 1 [P] COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur ---|--------------||------|||-------------|||-|--|-----|---------- 1 [S] COG2170 Uncharacterized conserved protein ---------|-------|--------||||||-|||||----|||||||||||||||||||||||| 1 [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase -------------------|||----||||||||-|||----|||||-|||||||----|||||-- 1 [D] COG2177 Cell division protein --------|-|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 1 [C] COG2180 Nitrate reductase delta subunit --------|-|---------------|||-----|-|-----|||-|--|-----|-----|---- 1 [C] COG2181 Nitrate reductase gamma subunit -------------|||---||---|-|---|||||||||---|||||-||||||||---||||--- 1 [K] COG2183 Transcriptional accessory protein ---------------------------||----|--------|||-|--||-|||-||-||-|--- 1 [D] COG2184 Protein involved in cell division ----------------|-||-------||--------------------|------------||-- 1 [S] COG2187 Uncharacterized protein conserved in bacteria --------------------|----||---||||||||-|||||||||||||---|-------|-- 1 [G] COG2190 Phosphotransferase system IIA components ------------------||-|-----||-|---||------|||||-||-----|--|||-||-- 1 [T] COG2205 Osmosensitive K+ channel histidine kinase ----------------||-|-|--||----|------|----------||-----|---|--|--- 1 [T] COG2206 HD-GYP domain ----------------------||---------------------|--||||-||----------- 1 [C] COG2209 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE |-||--||---------|---|----|-------||||----------||---------|||--|- 1 [P] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit ---|---------|||-|||-|--||----|---------|||||-|-||--|||-||||||||-- 1 [O] COG2214 DnaJ-class molecular chaperone ---|||------------||-|-----||-|---||------|||||--|-----|--|||-||-- 1 [P] COG2216 High-affinity K+ transport system, ATPase chain B ||||||||||||||---|||||----|||-|-||||||----|||||-||-||--|--|||||--| 1 [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold |-----||-|-------|--||--------|-||-||-----|||||--|--|------|||||-- 1 [M] COG2222 Predicted phosphosugar isomerases -----------|-||------|----||||-------|----|||||-||-----|---|||||-- 1 [C] COG2224 Isocitrate lyase ----------||-|-------|----||||-------|----|||||-||-----|---|||||-- 1 [C] COG2225 Malate synthase --|-||----||-||-||||||||--||||----||||----|||||-||-||||||||||||||| 1 [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis -------------||---||-|--------------------|||||-||-|||||---||||||| 1 [H] COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase --|-------------|----|----|||||-----------|||||-||-----|||||||||-- 1 [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases ---|||-----|-------------|-||--|||||----|-----|-||----------|-|--- 1 [E] COG2235 Arginine deiminase |----------------||||-|||||||-|---|-||||-----|--||--|||----||||||| 1 [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain) -------------||------|---||---|-|---------|||||--|||-------|||||-- 1 [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase ||||||--||||------|||-----|||-|----|----------|--|-----|---||||--- 1 [H] COG2241 Precorrin-6B methylase 1 ||||||--||||------|||-----|||-|----|----------|--|---------||||--- 1 [H] COG2242 Precorrin-6B methylase 2 ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2243 Precorrin-2 methylase ||||||||||-|-----|-|||----|---||||||||----|||||-||||||||---|||||-- 1 [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ---||||||||||-----||------||||||-||||-----|---|--|-----|------||-- 1 [S] COG2246 Predicted membrane protein -----------------||||||||||||||||||||||||||||||-|||||||||||||||||| 1 [L] COG2255 Holliday junction resolvasome, helicase subunit -------------||--|--||----|||||||||||||---|||||-||||||||||||||||-- 1 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase -----------------|------|-----|-----||-----------|------|||----|-- 1 [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB -------------------|-|----||||-||||-|-----|||||--|-----|---|||||-- 1 [S] COG2261 Predicted membrane protein -|||--||-||||---||||||||--||||||||||||----|||||-||-|||||---|||||-- 1 [R] COG2262 GTPases ----------------||||||--------||||||||----|||||-||||||||||||||||-- 1 [J] COG2264 Ribosomal protein L11 methylase ------------------||------|----|----||----|||-|--|------------|--- 1 [S] COG2268 Uncharacterized protein conserved in bacteria ---|-------||-------||----|||--||---------|||||-|||----|---|||||-- 1 [G] COG2301 Citrate lyase beta subunit --------------------||----|----|||-||-----|||||--|-----|---|--||-- 1 [S] COG2315 Uncharacterized protein conserved in bacteria ------------------|--|--------------||-----------|---------||||--- 1 [S] COG2318 Uncharacterized protein conserved in bacteria --||-----------------|-----|||------||----------||---------------- 1 [S] COG2320 Uncharacterized conserved protein ---------------------|----|||---|---------|||||--|-|---|---||||--- 1 [R] COG2321 Predicted metalloprotease ---|||-----||--------|----||||----||||-----------|-----|---||||--- 1 [R] COG2329 Conserved protein involved in polyketide biosynthesis related to monooxygenase --|------------------|--------------------|||||-|||||------||||||| 1 [O] COG2332 Cytochrome c-type biogenesis protein CcmE ---|---------------|-|--------||||||||----|||||-||||||||---------- 1 [R] COG2333 Predicted hydrolase (metallo-beta-lactamase superfamily) --------|----|-|---|||---||---|---||||-----------|---------|||||-- 1 [S] COG2340 Uncharacterized protein with SCP/PR1 domains ------------------||||----|---|-----|-----|||||-||||-|||---|||||-- 1 [S] COG2350 Uncharacterized protein conserved in bacteria --------------|------|--------------||----|||-|--|-----|--||||||-- 1 [R] COG2351 Transthyretin-like protein ------------------||-|----|--|--||--------|||||-||||-|||-------|-- 1 [C] COG2352 Phosphoenolpyruvate carboxylase ----||---------------|----|||-----||------|||||-||--|||||||||-||-- 1 [S] COG2353 Uncharacterized conserved protein ---------------------|----|||-------------|||-|-||---|-------|-|-- 1 [S] COG2354 Uncharacterized protein conserved in bacteria ---------------------|--------------|-----||||||||---------------- 1 [L] COG2356 Endonuclease I ------------------||-|--------------------|||||-||--||||--||||||-- 1 [O] COG2360 Leu/Phe-tRNA-protein transferase --------------|----|-|------------||||----|||||-||||-------|||||-- 1 [S] COG2363 Uncharacterized small membrane protein -------------||------|-----||--|---|---------|---|-----|---|---|-- 1 [T] COG2365 Protein tyrosine/serine phosphatase ----------------|-||-|---------------------------|-----|---|--|--- 1 [O] COG2370 Hydrogenase/urease accessory protein ------------------||-|----|-------|--||----|||---||----|||-||||--- 1 [O] COG2371 Urease accessory protein UreE -----------------|-|||--------------------|||||--|-||--|---||-|||| 1 [R] COG2373 Large extracellular alpha-helical protein ------------------||-|--|-|-----|---------------||---------------- 1 [R] COG2374 Predicted extracellular nuclease ---------------------|----|||-------------|||-|-||-----|---||----- 1 [P] COG2375 Siderophore-interacting protein ---------|--------||-|--------------------|||||-||||||||---|||||-- 1 [O] COG2377 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases --------------------||----|||||---||||----|---|-||--|-||--||||||-- 1 [K] COG2378 Predicted transcriptional regulator ----||||--|||----|---|---------------------------|-----|---||||--- 1 [G] COG2379 Putative glycerate kinase ---------------------|----|---|---||||----|||-|--|---------------- 1 [P] COG2382 Enterochelin esterase and related enzymes --|-----|------------|--------------------|||||-|||||------|||||-- 1 [O] COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component --------|---|-------||----|----|--||------|||---||-|-------|||||-- 1 [R] COG2388 Predicted acetyltransferase -||---||--||-||----|-|----|---------------||||--||---------------- 1 [T] COG2453 Predicted protein-tyrosine phosphatase ---------------------|----||||||||-|||-----------|---------|------ 1 [T Q] COG2508 Regulator of polyketide synthase expression ||----||-|---------|-------------------------|---|---||----|-|---- 1 [S] COG2510 Predicted membrane protein ||||--|||||||-|--|------------------------|||||-||--||||||||||||-- 1 [O] COG2518 Protein-L-isoaspartate carboxylmethyltransferase ------------------||--------------|-|------------|-----|--||--|--| 1 [V] COG2602 Beta-lactamase class D -|----------------------------------------|||-|--|--------|------- 1 [R] COG2603 Predicted ATPase ----------------|-||----------|------------------|---|||--||||||-- 1 [R] COG2607 Predicted ATPase (AAA+ superfamily) --||||--|--||||-||||||----|---|||-|||||-------|--|||-|||||-|||---- 1 [P] COG2608 Copper chaperone ---------------------|----||||------------||||||||||||||------||-- 1 [C] COG2609 Pyruvate dehydrogenase complex, dehydrogenase (E1) component -|--------------|-------------|-----------------||-----|--|------- 1 [P] COG2703 Hemerythrin --------------|---------------||-||||-----||||||-|-----|---------- 1 [G] COG2706 3-carboxymuconate cyclase ------------------|-----------|-----||-----------|-----|---------- 1 [R] COG2715 Uncharacterized membrane protein, required for spore maturation in B.subtilis. -------------------|-|--|-----|-----------|||||--|-|---|--||||-|-- 1 [S] COG2717 Predicted membrane protein ---|--------------------------|-----||----|||||-||----------|-|--- 1 [S] COG2718 Uncharacterized conserved protein ---|--------------------------|-----||----|||||-||----------|-|--- 1 [S] COG2719 Uncharacterized conserved protein ---------------------|----|---|-----||-----------|---------------- 1 [V] COG2720 Uncharacterized vancomycin resistance protein ----------------||------------|-----||----|||||-||-----|---------- 1 [K N U] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) ---|--------------------------|-----||----|||||-||----------|-|--- 1 [T] COG2766 Putative Ser protein kinase --------------|---||-|-----||-------------------||-----|---|||||-- 1 [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease ----------------||||||--------|-----------|||||-||--||||---------- 1 [N U] COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT -------------|-------|--------------||-----------|--|--|------||-- 1 [K] COG2808 Transcriptional regulator ----------------|||||||||||||||||||||||||||||||||||||||||||||||||| 1 [L] COG2812 DNA polymerase III, gamma/tau subunits --|----------||------|----|||-|-----------|||||-||||-------|||||-- 1 [L] COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding ---------------------|--------|--|--|------||-|--|---|----||---|-- 1 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily ------------------||----------------------||||||||||-|||---|||||-- 1 [M] COG2821 Membrane-bound lytic murein transglycosylase --------------------------|----|||-|------|||||-||||-|||||||||||-- 1 [P] COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism ----------------||---|||||----------------|||||-||||-|||-------||| 1 [M] COG2825 Outer membrane protein ---|----------------|----------|||||||----|||||-||---||-----||||-- 1 [L] COG2827 Predicted endonuclease containing a URI domain ------------------------------------|-----|||---||--||||---||-|--- 1 [S] COG2828 Uncharacterized protein conserved in bacteria --------------------||-----------||-------|||-|-||||-||----|||---- 1 [S] COG2832 Uncharacterized protein conserved in bacteria -|||----|-------|----|--||----|-----||----|||||-|||||||||||||||||| 1 [M] COG2834 Outer membrane lipoprotein-sorting protein --||------|||-------------||||------------|||||-||-|||||----||||-- 1 [S] COG2835 Uncharacterized conserved protein ---|---------------|----------|-----------------||---||||||------- 1 [S] COG2836 Uncharacterized conserved protein -------------------|-|----|||-----|||-----|||||-||-|-|||------|--- 1 [P] COG2837 Predicted iron-dependent peroxidase --------------------------||||------------------||--|||---|------- 1 [C] COG2838 Monomeric isocitrate dehydrogenase ------------------------|-----------------||||||||||||||---|||||-- 1 [S] COG2840 Uncharacterized protein conserved in bacteria ------------------------------------------|||----|-|-||-|||--|---- 1 [S] COG2841 Uncharacterized protein conserved in bacteria --------------------------|||-------------|||||-||||-|||---|||||-- 1 [O] COG2844 UTP:GlnB (protein PII) uridylyltransferase ----------|-----|----|----|---------------------||-|-|||--|||||||| 1 [S] COG2847 Uncharacterized protein conserved in bacteria --------------------|-||------------|--------||--|---||---|------- 1 [S] COG2849 Uncharacterized protein conserved in bacteria ------------------------------------|-----|||||--|||||||---------- 1 [S] COG2850 Uncharacterized conserved protein --------------------------|-----|-|-||-----------|--|||---|------- 1 [C] COG2851 H+/citrate symporter ------------------------------------------|||||-||||||||--|----||| 1 [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component --------|-----------|-----|----|||||------|||||--|||-|||--||||||-- 1 [S] COG2855 Predicted membrane protein -------------||-|-------------------||----------||--|||||||||||||| 1 [C] COG2857 Cytochrome c1 ---|------||---------|----|----||---||----|||||-||||---|--||||||-- 1 [S] COG2860 Predicted membrane protein -------------------------|-----------|----|||-|--|||------|||-||-- 1 [S] COG2861 Uncharacterized protein conserved in bacteria --|-------------|----|--------------------|||-||||||---|||||---|-- 1 [S] COG2862 Predicted membrane protein --|-----|-------|-------------------------|||||-||||---|--|-|----- 1 [C] COG2864 Cytochrome b subunit of formate dehydrogenase -------------||---------------------------|||||-||-|||||---||||||| 1 [I] COG2867 Oligoketide cyclase/lipid transport protein ----------------------||---------------------|--||||-||----------- 1 [C] COG2869 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC -|--------------|---|---------------------||||||-|||-||||||---||-- 1 [M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase ----------------------||---------------------|--||||-||----------- 1 [C] COG2871 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF --|-||||--||||---|--||--------|------|----------||-----|---||||--- 1 [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain --||---------||--|---|----|||-||---|-|-----------|-|---|--|||||--- 1 [E] COG2873 O-acetylhomoserine sulfhydrylase ||||||--||||------|||------||-|----|----------|--|-----|---||||--- 1 [H] COG2875 Precorrin-4 methylase ----------------|---|-||------------------|||||-|||||||||||||||||| 1 [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase --|--------------|--|---------------------||||||||||||||---------- 1 [C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB ------------------------------------------|||||--|---|||--|------- 1 [S] COG2879 Uncharacterized small protein -----------------|------|-----|-----||----||||||||-----|---------- 1 [N U O] COG2882 Flagellar biosynthesis chaperone -------------------|-|----||||||||-|||----|||||-|||||||----|||||-- 1 [D] COG2884 Predicted ATPase involved in cell division -------------------|----|------|-|||||----|||||-|||||--|---------- 1 [M] COG2891 Cell shape-determining protein ----------------||||||--------|----|||----||||||||--||||||-||||--- 1 [D] COG2894 Septum formation inhibitor-activating ATPase --------------------------|||-|-----------||||||||--||||---|||||-- 1 [P] COG2895 GTPases - Sulfate adenylate transferase subunit 1 --|-----------------------||||-|--|||------------|--|--|---|||||-- 1 [S] COG2898 Uncharacterized conserved protein ------------------------------------------|||||-|||||||----||||--- 1 [S] COG2900 Uncharacterized protein conserved in bacteria ------------------------------------------||||||||||||||---------- 1 [K L] COG2901 Factor for inversion stimulation Fis, transcriptional activator -------------||------------|||------------------||--|------||||||| 1 [E] COG2902 NAD-specific glutamate dehydrogenase ------------------------------------------|||||-|||||--|--------|| 1 [S] COG2904 Uncharacterized protein conserved in bacteria --------|-------|---------|----------|----------||---------------- 1 [T] COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains ------------------|---------|-------------||-||-||--||||-------|-- 1 [P] COG2906 Bacterioferritin-associated ferredoxin -------------------------------|-|-||-----------||-----|--|||-|--- 1 [R] COG2910 Putative NADH-flavin reductase ------------------------------------------||||||||||||||---|||||-- 1 [S] COG2911 Uncharacterized protein conserved in bacteria -------------------|--||------------------|||||||||||--|-------|-- 1 [S] COG2912 Uncharacterized conserved protein ------------------------------------------||||||||||||||---||||||| 1 [J] COG2913 Small protein A (tmRNA-binding) ------------------------------------------||||||||||||||---------- 1 [S] COG2914 Uncharacterized protein conserved in bacteria ------------------------------------------|||||||||||------------- 1 [R] COG2915 Uncharacterized protein involved in purine metabolism ------------------------------------------||||||||||-|||----|||||| 1 [D] COG2917 Intracellular septation protein A ------------------------------|----|------||||||||-|-------------- 1 [H] COG2918 Gamma-glutamylcysteine synthetase ------------------------||||||-|||||||----||||||||||||||---||||||| 1 [D] COG2919 Septum formation initiator --------|-|-------------------------------||||||||||-------------- 1 [P] COG2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit ------------------------------------------||||||||||||||---------- 1 [S] COG2921 Uncharacterized conserved protein |-|--------------|------------------------||||||||||-------------- 1 [P] COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur ------------------------------------------||||||||||||||---------- 1 [C O] COG2924 Fe-S cluster protector protein ------------------------------------------|||||||||||--|---------- 1 [L] COG2925 Exonuclease I ------------------------------------------|||||-||||||||---||||||| 1 [L] COG2927 DNA polymerase III, chi subunit ---|---------------||-||-------------|-----------|--||||---||-|--- 1 [S] COG2928 Uncharacterized conserved protein ----------------|-||-------------------------|--||--||||---||-||-- 1 [Q] COG2931 RTX toxins and related Ca2+-binding proteins ------------------------------------------|||||--||||------------- 1 [R] COG2933 Predicted SAM-dependent methyltransferase -------------||---------------------------------||--|--|--||||||-- 1 [O] COG2935 Putative arginyl-tRNA:protein arginylyltransferase ---------------------------|||------------|||||-|||||------------- 1 [I] COG2937 Glycerol-3-phosphate O-acyltransferase -------------||---------------------------|||||-||||||||---||||||| 1 [S] COG2938 Uncharacterized conserved protein -------------||----------------------------------|--|--|-------||| 1 [H] COG2941 Ubiquinone biosynthesis protein COQ7 ------------------------------------------|||-|-||--|--|-------|-- 1 [M] COG2943 Membrane glycosyltransferase ---|----|----------------------------------------|--||||---||||||| 1 [R] COG2945 Predicted hydrolase of the alpha/beta superfamily --------------|---||-|---------------------------|--|--|---||||--- 1 [S] COG2947 Uncharacterized conserved protein ---------------------|---------|-|-----------|---|--|---|||----|-- 1 [E] COG2957 Peptidylarginine deiminase and related enzymes -------------------------------------------------|--|--||||------- 1 [S] COG2958 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||-|||---------- 1 [H] COG2959 Uncharacterized enzyme of heme biosynthesis ------------------------------------------|||||-||--||||---||||--- 1 [S] COG2960 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||||||---|||||-| 1 [R] COG2961 Protein involved in catabolism of external DNA --------------------|-----------|---------|||||-||||---|--|-|----- 1 [S] COG2964 Uncharacterized protein conserved in bacteria ---------------------|--------------------|||||-||--|--|---|||||-- 1 [P] COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport ------------------------------------------|||||-||||||||---------- 1 [R] COG2969 Stringent starvation protein B --------------------|---------|-||||||----------||--|--|---------- 1 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain ------------------------------------------|||||-||||||||---------- 1 [L] COG2974 DNA recombination-dependent growth factor C ------------------------------------------|||||-|||--|||---------- 1 [S] COG2975 Uncharacterized protein conserved in bacteria ------------------------------------------||||||||||||||---------- 1 [S] COG2976 Uncharacterized protein conserved in bacteria --------------------------||||------------|||||-||---------|-||--- 1 [Q] COG2977 Phosphopantetheinyl transferase component of siderophore synthetase ------------------------------------------|||-|-||-|-||----||||--- 1 [S] COG2979 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||||||---------- 1 [M] COG2980 Rare lipoprotein B ------------------|-----------------------|||||-||||-------||||--- 1 [E] COG2981 Uncharacterized protein involved in cysteine biosynthesis -|----------------------------------------|||||-||||-------|||||-- 1 [S] COG2983 Uncharacterized conserved protein ---|||--------------||----------|-|-||-------|--||-----|---|||||-- 1 [E] COG2987 Urocanate hydratase ------------------||----------------------|||||-||---------------- 1 [E] COG2988 Succinylglutamate desuccinylase ---------------------------------------------|--||||-||----------- 1 [S] COG2991 Uncharacterized protein conserved in bacteria --------------------|---------||||||||----------||---------------- 1 [S] COG2996 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||------|||----- 1 [C] COG3005 Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit ------------------------------|--------------|--||--|------------- 1 [S] COG3007 Uncharacterized paraquat-inducible protein B ------------------------------------------|||||-||||-|||---------- 1 [R] COG3008 Paraquat-inducible protein B ------------------------------------------|||||-||---|||---------- 1 [S] COG3009 Uncharacterized protein conserved in bacteria ------------------||--------------|-||-------|--||--|--|------||-- 1 [S] COG3011 Uncharacterized protein conserved in bacteria ---------------------|----|---------------|||||-||||-|-|---------- 1 [S] COG3012 Uncharacterized protein conserved in bacteria ----------------|-------------------------------||--------|------- 1 [S] COG3016 Uncharacterized iron-regulated protein ------------------------------------------|||||-||||||||---------- 1 [M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis ----------|-----|-------------------------------||-|------|-|----- 1 [R] COG3019 Predicted metal-binding protein ----------------|---|-----|-----||--------|||||-||||-|||--|----|-| 1 [S] COG3022 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||-|||----||||-- 1 [S] COG3024 Uncharacterized protein conserved in bacteria --|---------------------------------------|||||-||||---|------||-- 1 [S] COG3025 Uncharacterized conserved protein ------------------------------------------|||||-||||---|---------- 1 [T] COG3026 Negative regulator of sigma E activity -----------------------|------|---||||----|||||-|||||||----||||||| 1 [S] COG3027 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||||||---------- 1 [S] COG3028 Uncharacterized protein conserved in bacteria --||----------------------||-------|||----|||||-||-|-||----||||--- 1 [R] COG3030 Protein affecting phage T7 exclusion by the F plasmid ----------------|-------------------------|||||-||------|||||||--- 1 [S] COG3034 Uncharacterized protein conserved in bacteria ------------------------------------------|--||-||||-|------------ 1 [S] COG3036 Uncharacterized protein conserved in bacteria --------------------------|---------------|||-|-||--------||--||-- 1 [M] COG3040 Bacterial lipocalin ------------------------------------------|||||-||||------|||----- 1 [C] COG3043 Nitrate reductase cytochrome c-type subunit ------------------------------------------|||||-||---|||---||||--- 1 [S] COG3045 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-||--|---|-||||| 1 [M] COG3047 Outer membrane protein W --------------------|---------------||----|||-|-||---------------- 1 [E] COG3048 D-serine dehydratase ----------------|-------------------------|||||--|||--------|----- 1 [O] COG3058 Uncharacterized protein involved in formate dehydrogenase formation ------------------------------------------|||||-||||------|||----- 1 [P] COG3062 Uncharacterized protein involved in formation of periplasmic nitrate reductase ---------------------------------------------|--||||||||---------- 1 [N U] COG3063 Tfp pilus assembly protein PilF ------------------------------------------|||||-||||-------------- 1 [P] COG3067 Na+/H+ antiporter ------------------------------|--|||------|||||-||||-|-|----|-||-| 1 [K] COG3070 Regulator of competence-specific genes ------------------------------------------|||||-||||||||---------- 1 [H] COG3071 Uncharacterized enzyme of heme biosynthesis ------------------------------------------|||||-||||-------------- 1 [F] COG3072 Adenylate cyclase ------------------------------------------|||||-|||||--|---------- 1 [T] COG3073 Negative regulator of sigma E activity ------------------------------------------|||||-|||||------------- 1 [S] COG3079 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||-------------- 1 [R] COG3081 Nucleoid-associated protein ------------------------------------------|||||-||||-------------- 1 [R] COG3083 Predicted hydrolase of alkaline phosphatase superfamily -----------------|--|---------------------|||||-||||-------------- 1 [T] COG3086 Positive regulator of sigma E activity ------------------------------------------|||||-||||||||---------- 1 [D] COG3087 Cell division protein ---------------------|--------------------|||||--||||------|||||-- 1 [O] COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes ------------------------------------------|||||-||||-------------- 1 [S] COG3089 Uncharacterized protein conserved in bacteria -------------------------------|||||||----|||||-||||-------------- 1 [S] COG3091 Uncharacterized protein conserved in bacteria -------------------||-----|---------------|||---|||-|-------|-||-- 1 [R] COG3093 Plasmid maintenance system antidote protein ------------------------------------------|||||-||||-------------- 1 [S] COG3098 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||||-------------- 1 [S] COG3100 Uncharacterized protein conserved in bacteria -----------------------------------||-----|||||-||||-------------- 1 [T] COG3103 SH3 domain protein ------------------------------------------|||||-||||-------------- 1 [S] COG3105 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-|||||------------- 1 [R] COG3107 Putative lipoprotein ------------------------------------------|||||-||||-------------- 1 [T] COG3109 Activator of osmoprotectant transporter ProP ------------------------------------------|||||-||||-------------- 1 [S] COG3111 Uncharacterized conserved protein ------------------------------------------|||||-||||-------------- 1 [U] COG3114 Heme exporter protein D ------------------------------------------|||||-|||||------------- 1 [D] COG3115 Cell division protein ------------------------------------------|||||||||||--|---------- 1 [D] COG3116 Cell division protein ------------------------------------------|||||-||||||||---------- 1 [S] COG3117 Uncharacterized protein conserved in bacteria --------------------------||||------------|||||-|||||--|---|||||-- 1 [O] COG3118 Thioredoxin domain-containing protein ------------------------------------------|||||--|--|------------- 1 [S] COG3122 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-----|---------- 1 [S] COG3123 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||---------------- 1 [S] COG3124 Uncharacterized protein conserved in bacteria ----------------------------------||||----||||||-|--|--|---|-|||-- 1 [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4 ------------------------------------------|||||-||-----|---|||||-- 1 [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component ------------------------------------------|||----|--|---------||-- 1 [S] COG3128 Uncharacterized iron-regulated protein --------------|---------------------------|||||-||---------------- 1 [R] COG3129 Predicted SAM-dependent methyltransferase ------------------------------------------|||||-||---------------- 1 [J] COG3130 Ribosome modulation factor ------------------------------------------|||-|-||--|--|---------- 1 [P] COG3131 Periplasmic glucans biosynthesis protein ------------------------------------------|||||-||------------|--- 1 [S] COG3132 Uncharacterized protein conserved in bacteria ------------------------------------------|||||--|||---|---------- 1 [M] COG3133 Outer membrane lipoprotein ------------------------------------------|||||--|--|------------- 1 [S] COG3134 Predicted outer membrane lipoprotein ---------------------|----|---------------|||-|-||----------|||--- 1 [Q] COG3135 Uncharacterized protein involved in benzoate metabolism ------------------------------------------|||||-||------------|--- 1 [R] COG3136 Uncharacterized membrane protein required for alginate biosynthesis ------------------------------------------|||||-||---------------- 1 [S] COG3139 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||---------------- 1 [S] COG3141 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-----|---------- 1 [N T] COG3143 Chemotaxis protein -----------------|------------|-----||----||||||||-----|---------- 1 [N] COG3144 Flagellar hook-length control protein --------------|----|------||||------------|||-|-||--|--|---|||||-- 1 [L] COG3145 Alkylated DNA repair protein ------------------||-----------------------------|--|--|---|||||-- 1 [S] COG3146 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||--|--|---------- 1 [S] COG3147 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-|---|---------- 1 [R] COG3150 Predicted esterase ------------------------------------------|||||-||--|------------- 1 [S] COG3151 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||-----|---|||---- 1 [I] COG3154 Putative lipid carrier protein ------------------------------------------|||||-||---------------- 1 [Q] COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis --|-----------------------|----||---------|||||-||--|--|---|||||-- 1 [P] COG3158 K+ transporter ------------------------------------------|||||-||-||--|-------|-- 1 [S] COG3159 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||---------------- 1 [K] COG3160 Regulator of sigma D |||-----||-----------------|||------------|||||-||-|-|||---------- 1 [H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase) ---------------------|----|---------|-----|||||--|--|------------- 1 [S] COG3162 Predicted membrane protein ------------------------------------------|||||-||--|--|---------- 1 [S] COG3164 Predicted membrane protein ------------------------------------------|||||-||-|||||---------- 1 [S] COG3165 Uncharacterized protein conserved in bacteria ------------------||----------------------|||||-||--||||------|--- 1 [N U] COG3166 Tfp pilus assembly protein PilN ------------------------------------------------||--||||---------- 1 [N U] COG3167 Tfp pilus assembly protein PilO ------------------------------------------------||--||||---------- 1 [N U] COG3168 Tfp pilus assembly protein PilP ---------------------|--------------------------||--|-------||---- 1 [S] COG3169 Uncharacterized protein conserved in bacteria ---------------------------||--|----------|||||--|||-------------- 1 [H] COG3172 Predicted ATPase/kinase involved in NAD metabolism --||-----------------|-----||--|---|||-----------|-----|---||-||-| 1 [R] COG3173 Predicted aminoglycoside phosphotransferase |-||-----|--|---|--------------------------------|-----|----|-|--- 1 [S] COG3174 Predicted membrane protein -------------||----------------------------------|-----|---||||||| 1 [O] COG3175 Cytochrome oxidase assembly factor -------------------|-------||-------------------||-----|---|||||-- 1 [R] COG3176 Putative hemolysin --||------------|--||-----|-----|-||-------|||---|-|-|||||-||-|--| 1 [S] COG3177 Uncharacterized conserved protein -------------------------------------------------|--||||---|||||-- 1 [R] COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases ---------------------|------------------------|--||---------|----- 1 [R] COG3179 Predicted chitinase -------------------||-----|-------|-||----|||-|-||---------||-|--- 1 [R] COG3180 Putative ammonia monooxygenase --|------------------|------------------------|-||------------|--- 1 [V] COG3183 Predicted restriction endonuclease -------------------------------------------------|--|||----||||--- 1 [S] COG3184 Uncharacterized protein conserved in bacteria -----------------------|------------------------||-----|------||-- 1 [E] COG3186 Phenylalanine-4-hydroxylase --|---------------|-||----|---------------|||||-||-----||||||||--- 1 [O] COG3187 Heat shock protein ----||-----|--------------|||-----|-------|||-|--|-----|---||||--- 1 [S] COG3189 Uncharacterized conserved protein ----------------------||------------||----||||||||-----|---------- 1 [N] COG3190 Flagellar biogenesis protein ------||---|---------|----||||-------------------|-----|---|||||-- 1 [E Q] COG3191 L-aminopeptidase/D-esterase --------------------|--------------||-----|||-|--|---------------- 1 [E] COG3192 Ethanolamine utilization protein -------------||---------------------------|||-|--|---------||||--- 1 [F] COG3194 Ureidoglycolate hydrolase ---------------------|----|---------||-----------|-----|---|||||-- 1 [S] COG3195 Uncharacterized protein conserved in bacteria ---------------------------||-------------|------|---------------- 1 [S] COG3196 Uncharacterized protein conserved in bacteria ------------------------------------------------||---||||||-|-||-- 1 [P] COG3197 Uncharacterized protein, possibly involved in nitrogen fixation ------------------------------------------------||---||----------- 1 [S] COG3198 Uncharacterized protein conserved in bacteria --------------------------|----|||--------|||||--|||----||-------- 1 [H] COG3201 Nicotinamide mononucleotide transporter ----------------||||----------------------|||-|-||-||--|---|||||-- 1 [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis -------------|----------------------------------||---------------- 1 [Q] COG3207 Pyoverdine/dityrosine biosynthesis protein -------------------|-----------------|----------||--------|||-||-- 1 [R] COG3211 Predicted phosphatase ------------------------------------------------||---|||---|||---- 1 [P] COG3213 Uncharacterized protein involved in response to NO ---------------------|-----||-------------|||-|--|---------||-||-- 1 [S] COG3214 Uncharacterized protein conserved in bacteria -------------------------------------------------|--||||---------- 1 [N U] COG3215 Tfp pilus assembly protein PilZ ------------------|-----------------------------||---------||||--- 1 [S] COG3216 Uncharacterized protein conserved in bacteria ---|---------------|----------------------|||||-||---------||-||-- 1 [R] COG3217 Uncharacterized Fe-S protein -------------------------------------------------|--|-----||||||-- 1 [R] COG3218 ABC-type uncharacterized transport system, auxiliary component ------------------||-------||--------------------|---------------- 1 [S] COG3222 Uncharacterized protein conserved in bacteria -------------------------------|---||-----|||||--||--------------- 1 [S] COG3223 Predicted membrane protein ------------------||-|---------------------------|---------------- 1 [S] COG3224 Uncharacterized protein conserved in bacteria ---------------------------||-------------|||-|--|---------------- 1 [S] COG3226 Uncharacterized protein conserved in bacteria --|----------------|----------|---|-|-----------||---------------- 1 [E] COG3227 Zinc metalloprotease (elastase) ------------------||----------------------|||||--|-----|---------- 1 [S] COG3228 Uncharacterized protein conserved in bacteria ---------------------|-----||--|-----------------|----------|-|--- 1 [J] COG3231 Aminoglycoside phosphotransferase -|----||------------------|||--------------------|-----|---------- 1 [R] COG3233 Predicted deacetylase -----------------|------------------------|||----|-----|---------- 1 [S] COG3234 Uncharacterized protein conserved in bacteria ------------------------------------------------||---||----------- 1 [S] COG3235 Predicted membrane protein -------------------|-|----|---------------|------|---------------- 1 [S] COG3236 Uncharacterized protein conserved in bacteria -------------------|------|----||||||-----|||-|--|---------||-||-- 1 [S] COG3237 Uncharacterized protein conserved in bacteria -------------------------------------------------|--|||----------- 1 [C] COG3241 Azurin ------------------------------------------|||||-||--|--|-----||--- 1 [S] COG3242 Uncharacterized protein conserved in bacteria --------|-----------||-----|---------------------|-----|---||-|--- 1 [S] COG3246 Uncharacterized conserved protein --|----------------|-------||--|--||------||||---|-----|----|||--- 1 [S] COG3247 Uncharacterized conserved protein ------------------------------------------|||-|-||---------------- 1 [M] COG3248 Nucleoside-binding outer membrane protein ------------------------------------------------||--|---------|--- 1 [S] COG3249 Uncharacterized protein conserved in bacteria ---------------------------||-------|------|--|--|-----|---|------ 1 [S] COG3251 Uncharacterized protein conserved in bacteria ----||--|-|||---|--------------------|-----------|------------||-- 1 [I] COG3255 Putative sterol carrier protein ----------||------|------------------------------|---|||---|||---- 1 [P] COG3256 Nitric oxide reductase large subunit ---------------------|--------------------|||-|--|---------||||--- 1 [R] COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization --------------------|----------------|----|||-|-||---------|--|--- 1 [P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain -------------||----|-|----|---------------|||||-||-|-|||---||-|--- 1 [G] COG3265 Gluconate kinase ------------------------------------------|||||-||---------------- 1 [S] COG3266 Uncharacterized protein conserved in bacteria ---|-----------|--|--------|||-------------------|-----------|---- 1 [S] COG3268 Uncharacterized conserved protein |-|---------------------------------------|||||-||---------------- 1 [S] COG3272 Uncharacterized conserved protein -||-||---|-|----|-------------------------|||-|--|||------|-|----- 1 [J] COG3276 Selenocysteine-specific translation elongation factor --------------------|---------||||||||----|||||-||--|--|---|||||-- 1 [K T] COG3279 Response regulator of the LytR/AlgR family -----------|-------|-|----|||-----------------|--|-----|----|----- 1 [G] COG3280 Maltooligosyl trehalose synthase ------------|-------------|||--------------------|-----|---------- 1 [G] COG3281 Uncharacterized protein, probably involved in trehalose biosynthesis ---------------------------||-------||-----------|---------||-|--- 1 [L] COG3285 Predicted eukaryotic-type DNA primase -|-------|---------|----------------------------||----------|-|--- 1 [S] COG3287 Uncharacterized conserved protein ------------------||-|------------|--------------|---------------- 1 [S] COG3296 Uncharacterized protein conserved in bacteria ------------------------------------------|--|--||-------------|-- 1 [U] COG3297 Type II secretory pathway, component PulL -----------------||||---------|--||-------|||||-||||||||||-||||||| 1 [M] COG3307 Lipid A core - O-antigen ligase and related enzymes ------------------------------------------------||---|||---------- 1 [S] COG3308 Predicted membrane protein ------------------------------------------|||||-||||-||----------- 1 [C] COG3312 F0F1-type ATP synthase, subunit I ------------------------------------------|||||-||||-|||---------- 1 [M] COG3317 Uncharacterized lipoprotein ----------------------||------------|-----|||-|-||---||----------- 1 [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA -------------||----|-------|||----|--------------|---------|------ 1 [Q] COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes --------------------|-----||-||---||||-----------|---------------- 1 [S] COG3323 Uncharacterized protein conserved in bacteria --|-----------------------|||--------|--------|-||-|---|---|||||-- 1 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase --|----------------------------|||-|||--------|--|---||-|--|------ 1 [S] COG3326 Predicted membrane protein -------------|-----------------------|-----------|-----|---------- 1 [S] COG3332 Uncharacterized conserved protein ---|------|||------------------------|-----------|---------------- 1 [S] COG3342 Uncharacterized conserved protein --|----------|----|||------||-|---|--|----|--||-||----------|----- 1 [L] COG3344 Retron-type reverse transcriptase -------------||-----------||||-------------------|-----|---||||||| 1 [S] COG3346 Uncharacterized conserved protein ---|-----------------------||--------------------|-----|----|----- 1 [S] COG3360 Uncharacterized conserved protein ---|--------------||-----------------------------|-----|---------- 1 [R] COG3380 Predicted NAD/FAD-dependent oxidoreductase ---------||||-----------------|||---||--------|--|-----|------|--- 1 [S] COG3382 Uncharacterized conserved protein ----||-----|-|-------|------------|-|---------|--|-||--|---|||||-- 1 [G] COG3386 Gluconolactonase --|-|------|-------|-|--||-||-|-----||----|||-|--|-----|----|-|--- 1 [S] COG3391 Uncharacterized conserved protein -------------------------------|---|-|-------|--||---------------- 1 [S] COG3397 Uncharacterized protein conserved in bacteria -----------------------------------------------|-|--|--|---|------ 1 [S] COG3416 Uncharacterized protein conserved in bacteria ------------------------------------------||||||||---------------- 1 [N U O] COG3418 Flagellar biosynthesis/type III secretory pathway chaperone -------------------------------------------------|--|-||---------- 1 [N U] COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 ----------|--------------------------------------|---|||----||---- 1 [P] COG3420 Nitrous oxidase accessory protein --|---------------------------------------||||---|-|-||----|-|||-- 1 [S] COG3422 Uncharacterized conserved protein ---------------------------||-------|-----|||||-||-----------|---- 1 [Q] COG3433 Aryl carrier domain -----------|--------------|----------|-----||-|--|-----|---------- 1 [Q] COG3435 Gentisate 1,2-dioxygenase ------------------||----------------------|||-|--|----------|-|--- 1 [T] COG3447 Predicted integral membrane sensor domain ------------------|------------------------------|-----|---||-|--- 1 [T] COG3448 CBS-domain-containing membrane protein -------------------|----------------------||||---|---------||||--- 1 [P] COG3454 Metal-dependent hydrolase involved in phosphonate metabolism -------------------------------|---|------------||---------------- 1 [G] COG3469 Chitinase -------------------------------------------------|-|-|||---------- 1 [S] COG3471 Predicted periplasmic/secreted protein ---------------------|---------------------------|-----|------||-- 1 [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion) ------------------|------------------------------|-----|------|--- 1 [O] COG3484 Predicted proteasome-type protease ---|----------|----|-----------------|-------|---|-----|----|-|--- 1 [Q] COG3486 Lysine/ornithine N-monooxygenase ------------------------------------------------||---------||-|--- 1 [P] COG3487 Uncharacterized iron-regulated protein ------------------------------------------------||---------||-|--- 1 [C] COG3488 Predicted thiol oxidoreductase ------------------------------------------------||---------||-|--- 1 [R] COG3489 Predicted periplasmic lipoprotein ------------------------------------------------||---------||-|--- 1 [S] COG3490 Uncharacterized protein conserved in bacteria ------------------------------------------------||---------||-||-- 1 [S] COG3492 Uncharacterized protein conserved in bacteria -------------------|-----------------------||||--|--|--|---|--|--- 1 [R] COG3497 Phage tail sheath protein FI -------------------------------------------||-|--|--|--|---------- 1 [R] COG3498 Phage tail tube protein FII -------------------------------------------||-|--|--|--|---|------ 1 [R] COG3499 Phage protein U -------------------|----------------------|||-|--|--|--|---|--|--- 1 [R] COG3500 Phage protein D |-|-----|----------------------------------------|-----|---|||||-- 1 [S] COG3503 Predicted membrane protein -----------|------------------------------------||-----|----|-||-- 1 [Q] COG3508 Homogentisate 1,2-dioxygenase --------------------------||||-------------------|-----|---||-||-- 1 [Q] COG3509 Poly(3-hydroxybutyrate) depolymerase ------------------------------------------------||---------||||--- 1 [O] COG3526 Uncharacterized protein conserved in bacteria -------------------------------------------|-||-||---------------- 1 [R] COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain -------------------------------------------|-||-||-----|---------- 1 [S] COG3530 Uncharacterized protein conserved in bacteria -------------------|------|---------|------------|----------|-||-- 1 [P] COG3540 Phosphodiesterase/alkaline phosphatase D -|-----------------|----------|-----|------------|-----|------|--- 1 [R] COG3541 Predicted nucleotidyltransferase ---------------------|------------|-||-----------|-----|---|||||-- 1 [R] COG3545 Predicted esterase of the alpha/beta hydrolase fold ----------|--------|----------|-----||-----||-|--|---------------- 1 [P] COG3546 Mn-containing catalase -------------------------------------|-----------|------------|--- 1 [S] COG3551 Uncharacterized protein conserved in bacteria ------------------------------------------------||-----------|||-- 1 [S] COG3553 Uncharacterized protein conserved in bacteria ---------------------------||--------------------|----------|-|--- 1 [S] COG3554 Uncharacterized protein conserved in bacteria ------------------|------------------------------|-----|------|--- 1 [S] COG3556 Predicted membrane protein ------------------|------------------------------|---------|--|--- 1 [S] COG3558 Uncharacterized protein conserved in bacteria -------------|----------------||--||-------------|---||----|-|---- 1 [R] COG3560 Predicted oxidoreductase related to nitroreductase ------------------|------------------------------|---------|--|--- 1 [R] COG3565 Predicted dioxygenase of extradiol dioxygenase family -------------||------|---------------------------|---------||-|--- 1 [L] COG3569 Topoisomerase IB ---------------------|---------------------------|---------||-|--- 1 [V] COG3570 Streptomycin 6-kinase ---------------------------||--------------------|----------|-|--- 1 [R] COG3571 Predicted hydrolase of the alpha/beta-hydrolase fold |||----------------|||-----|||--|----------------|---------||-||-- 1 [R] COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase --|----------------|-----------------------------|||---|------|--- 1 [H] COG3585 Molybdopterin-binding protein -||---------------|-|---------------------|||||-||-|-------|--|--- 1 [L] COG3593 Predicted ATP-dependent endonuclease of the OLD family --|---------------------------|---|||------------|--|---------|--- 1 [G] COG3594 Fucose 4-O-acetylase and related acetyltransferases ------------------------------------------------||----------|-||-- 1 [S] COG3602 Uncharacterized protein conserved in bacteria ------------------------------------------|||||-||---------|||||-- 1 [T] COG3605 Signal transduction protein containing GAF and PtsI domains |--|-----|--------------------------------------||---------||||--- 1 [R] COG3608 Predicted deacylase ------------------|--|--------------------------||------------|--- 1 [T] COG3614 Predicted periplasmic ligand-binding sensor domain -------------||-----|-----|||--------------------|-----|---|||||-- 1 [E] COG3616 Predicted amino acid aldolase or racemase ---------------------------------------------|---|-----|--|||||--- 1 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold --|---------------|-|------||-||||-||------------|-----|---||||--- 1 [S] COG3619 Predicted membrane protein -------------------|----------------------||||---|---------||-|--- 1 [P] COG3624 Uncharacterized enzyme of phosphonate metabolism -------------------|----------------------||||---|---------||-|--- 1 [P] COG3625 Uncharacterized enzyme of phosphonate metabolism -------------------|----------------------||||---|---------||-|--- 1 [P] COG3626 Uncharacterized enzyme of phosphonate metabolism -------------------|----------------------||||---|---------||-|--- 1 [P] COG3627 Uncharacterized enzyme of phosphonate metabolism -------------------|-------------------------||--|--|--|------|--- 1 [R] COG3628 Phage baseplate assembly protein W --------------------------------|---------|||||-||||-||---|------- 1 [E] COG3633 Na+/serine symporter -------------------------------||-|-|-----|||-|--|--|--|-------|-- 1 [O] COG3634 Alkyl hydroperoxide reductase, large subunit ---------------------|---------------------------|-----|-------|-- 1 [S] COG3644 Uncharacterized protein conserved in bacteria -------------------|----------------------------||-------------|-- 1 [S] COG3650 Predicted membrane protein -------------------|-------------|-----|-----||-||---|-------|-|-- 1 [R] COG3654 Prophage maintenance system killer protein ---------------------------||--------------------|-----|-------|-- 1 [S] COG3662 Uncharacterized protein conserved in bacteria ----------------------------------||-|-----------|----------|--|-- 1 [G] COG3664 Beta-xylosidase -------------------------------------------------|--|--|-------|-- 1 [P] COG3667 Uncharacterized protein involved in copper resistance ------------------------------------------------||---------|||||-- 1 [S] COG3672 Predicted periplasmic protein -------------|-----------------------------------|-------------|-- 1 [S] COG3673 Uncharacterized conserved protein ------------------||----------------------|||||-||----||----|----- 1 [U N T P] COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein -------------------|----------------------|||-|--|---------||-|--- 1 [S] COG3685 Uncharacterized protein conserved in bacteria -------------------|-----------------------------|---|||---|-|-|-- 1 [S] COG3686 Predicted membrane protein --------------|------|----|||--|---|------|||||-||---------------- 1 [L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase ----------------|-||----------------------|||-|--|-----|||--|--|-- 1 [P] COG3696 Putative silver efflux pump ----------------|-||-|--------||---|||-----------|---|||---|||||-- 1 [E] COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis --------------------|---------|---||||-----------|-|-------||-|--- 1 [S] COG3708 Uncharacterized protein conserved in bacteria ------------------------------------------||||---|---------||||--- 1 [P] COG3709 Uncharacterized component of phosphonate metabolism -------------------------------------------|||---|-----|----|-|--- 1 [P] COG3720 Putative heme degradation protein ------------------------------------------|||||--|-------------|-- 1 [E] COG3724 Succinylarginine dihydrolase ------------------------------------------|||||--|--|------------- 1 [V] COG3725 Membrane protein required for beta-lactamase induction ------------------------------------------|||||-||-|-------------- 1 [R] COG3726 Uncharacterized membrane protein affecting hemolysin expression -------------------------------||-|||------|||---|------------|--- 1 [L] COG3728 Phage terminase, small subunit ------------------------------------------|||-|--|-|-----------|-- 1 [S] COG3738 Uncharacterized protein conserved in bacteria ---------------------|-----------------------|---|---------|||||-- 1 [E] COG3741 N-formylglutamate amidohydrolase -------------------------------------------------|-----|---||-||-- 1 [U] COG3745 Flp pilus assembly protein CpaB -------------------------------------------------|-----|---|||||-- 1 [S] COG3748 Predicted membrane protein -------------|||--||----------------------------||-------------|-- 1 [O] COG3751 Predicted proline hydroxylase ------------------------------------------|||----|-----|----|||--- 1 [S] COG3753 Uncharacterized protein conserved in bacteria -------------------|-|--------------------|||-|--|---------||-||-- 1 [S] COG3755 Uncharacterized protein conserved in bacteria --------------------|-----------|---------||||---|-----|---||||--- 1 [S] COG3758 Uncharacterized protein conserved in bacteria -------------------------------|-----------------|---------|||||-- 1 [S] COG3760 Uncharacterized conserved protein -------------||----------------------------------|-----------|-|-- 1 [S] COG3777 Uncharacterized conserved protein ------------------------------------------------||---||----------- 1 [S] COG3782 Uncharacterized protein conserved in bacteria ------------------------------------------|||||--|-------------|-- 1 [S] COG3784 Uncharacterized protein conserved in bacteria ------------------------------------------|||-|--|-------------|-- 1 [S] COG3789 Uncharacterized protein conserved in bacteria -------------------------------------------------|---------|||||-- 1 [S] COG3802 Uncharacterized protein conserved in bacteria ----------------------------------------------|--|----------|-||-- 1 [S] COG3811 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|------||-- 1 [S] COG3812 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|---||-||-- 1 [S] COG3813 Uncharacterized protein conserved in bacteria -------------------------------------------------|---------|||||-- 1 [S] COG3816 Uncharacterized protein conserved in bacteria -------------------------------------------------|---------||-||-- 1 [S] COG3821 Predicted membrane protein -------------------|-----------------------------|-----|------||-- 1 [S] COG3825 Uncharacterized protein conserved in bacteria -||-----|||---------------||||||-|-|-------------|---||----------- 1 [T] COG3830 ACT domain-containing protein --|--------------|--------|||-|---||||-----------|-----|---||-||-- 1 [S] COG3832 Uncharacterized conserved protein ------------------------------|-----||----|||||-|||--------------- 1 [K T] COG3835 Sugar diacid utilization regulator ---------------------|------------|-------|||||--|-|---|---||||--- 1 [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase ---|---------|-------|---------------------------|-----|------|--- 1 [E] COG3844 Kynureninase ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG3845 ABC-type uncharacterized transport systems, ATPase components -------------------------------------------------|-|---|---||-||-- 1 [U] COG3847 Flp pilus assembly protein, pilin Flp ------------------------------------------|||||-||||-|||---------- 1 [T] COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific ------------------------------------------|||||-||--|--|---|||||-- 1 [T] COG3852 Signal transduction histidine kinase, nitrogen specific ----------------|----|--------|------------------|-----|---------- 1 [S] COG3868 Uncharacterized conserved protein ------------------|-----------------------|||||--|-----|---|||---- 1 [R] COG3895 Predicted periplasmic protein -------------------------------------------------|---|||----||---- 1 [K] COG3901 Regulator of nitric oxide reductase transcription -------------------------------------------------|----------|-|--- 1 [S] COG3904 Predicted periplasmic protein -------------------------------------------------|--|------||-||-- 1 [K] COG3905 Predicted transcriptional regulator ---------------------------------------------|---|--|------------- 1 [R] COG3907 PAP2 (acid phosphatase) superfamily protein -------------------------------------------------|---||----||-|--- 1 [C] COG3909 Cytochrome c556 -------------------------------------------------|-----|---|--|--- 1 [S] COG3913 Uncharacterized protein conserved in bacteria ------------------------------------------------||---------|------ 1 [S] COG3915 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|---|---|-- 1 [Q] COG3917 2-hydroxychromene-2-carboxylate isomerase ----------------------------------------------|--|---------||||--- 1 [S] COG3921 Uncharacterized protein conserved in bacteria ------------------------------------------------||---------||----- 1 [S] COG3930 Uncharacterized protein conserved in bacteria -------------------------------------------------|---------||||--- 1 [E] COG3931 Predicted N-formylglutamate amidohydrolase --------------------------------------------||--|||--------------- 1 [R] COG3941 Mu-like prophage protein ---------------------------------------------||--|---||----------- 1 [R] COG3943 Virulence protein -------------------------------------------------|--|--|---|||---- 1 [U] COG3946 Type IV secretory pathway, VirJ component ----------------------------------------------|--|--|--|---------- 1 [R] COG3948 Phage-related baseplate assembly protein ------------------------|-----------------||||||||-----|---------- 1 [M N O] COG3951 Rod binding protein --------------|---||----------||-----------------|----------|||--- 1 [G] COG3957 Phosphoketolase ------------------------------------------|||-|--|-----|----|-|--- 1 [R] COG3960 Glyoxylate carboligase -------------------------------||--|------|||-|--|-----|---------- 1 [R] COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase ---------------------|-----||-------------|||||--|-|---|---|-|-|-- 1 [Q] COG3971 2-keto-4-pentenoate hydratase ----------------------------------------------|--|--|------|------ 1 [R] COG3972 Superfamily I DNA and RNA helicases ---|---------------------------|---|-|-------||-||---------------- 1 [R] COG3979 Uncharacterized protein contain chitin-binding domain type 3 -------------------|----------|--|--------------||---------------- 1 [P] COG4097 Predicted ferric reductase ----------------|-------------------------|||||||||||||||||||||||| 1 [R] COG4105 DNA uptake lipoprotein ---------------------|-----||-------------||||---|---------||||--- 1 [R] COG4106 Trans-aconitate methyltransferase -------------------|----------------------||||---|---------||-|--- 1 [P] COG4107 ABC-type phosphonate transport system, ATPase component ------------------||-|----|---||||||------||||||||||||||---|||||-- 1 [J] COG4108 Peptide chain release factor RF-3 -------------------|----------------------|||-|--|-----|-----||--- 1 [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) --------------------|-----|-----||--------------||-----|---||||-|| 1 [R] COG4120 ABC-type uncharacterized transport system, permease component ||--------------|-||-|---|----------------|||||-||||---|--|||--|-- 1 [S] COG4121 Uncharacterized conserved protein ---------------------------------------------|--||---------------- 1 [R] COG4128 Zonula occludens toxin -------------------------------------------------|--------|||||--- 1 [R] COG4132 ABC-type uncharacterized transport system, permease component ------------------------------------------|||||-|||||------||||||| 1 [O] COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component ------------------------------------------|||||-||-|||||---------- 1 [R] COG4137 ABC-type uncharacterized transport system, permease component --------|-------|--|-|----|---------||----|||||-||--|--|---------- 1 [R] COG4147 Predicted symporter ----------------------------------|-------|||||-||||-------||||--- 1 [P] COG4148 ABC-type molybdate transport system, ATPase component --|---------|---|-||------|||-----||||----|||||-||||---|||||||||-- 1 [P] COG4149 ABC-type molybdate transport system, permease component ------------------------------------------|||||-||-----|---||-||-- 1 [Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component ------------------||-----------------|-----------|-----|---|---|-- 1 [R] COG4188 Predicted dienelactone hydrolase ---|---------------------------------------------|----------|----- 1 [K] COG4190 Predicted transcriptional regulator ------------------------------------------|||||-||-----|-----|-|-- 1 [H] COG4206 Outer membrane cobalamin receptor protein ------------------||-------||--------|----|||||-||--||||---|||||-- 1 [P] COG4208 ABC-type sulfate transport system, permease component ---|---------||---||||----|||--|-|||------|||-|-||||||||||||||---- 1 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity -------------||-|--------------------------------|--|------------- 1 [C] COG4229 Predicted enolase-phosphatase ------------------------------------------|||||--|-|-|||---|||||-- 1 [C] COG4230 Delta 1-pyrroline-5-carboxylate dehydrogenase ------------------------------------------|||||--||||------|||||-- 1 [O] COG4235 Cytochrome c biogenesis factor ----------------|-||-----------------------------|----------|-|--- 1 [S] COG4244 Predicted membrane protein ------------------||-|---------------------------|---------|------ 1 [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase) ------------------||-|---------------------------|-----|----|--|-- 1 [T] COG4252 Predicted transmembrane sensor domain -------------------------------------------------|-----|----|--|-- 1 [S] COG4254 Uncharacterized protein conserved in bacteria ------------------|------------------------------|-----|---------- 1 [V] COG4257 Streptogramin lyase ---------------------------------------------|---|---|||---------- 1 [S] COG4259 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|----||---- 1 [C] COG4263 Nitrous oxide reductase -------------||----------------------------------|-----|----|----- 1 [F] COG4266 Allantoicase -----------------|--|---------|------------------|-----|---------- 1 [S] COG4267 Predicted membrane protein -------------------|-|------------|--------------|---------------- 1 [S] COG4270 Predicted membrane protein --|---|------------------------------------------|-----|---------- 1 [S] COG4273 Uncharacterized conserved protein -----------|-------|-----------------------------|-----|---------- 1 [S] COG4278 Uncharacterized conserved protein --------------------|---------|----|------|||-|--|-----|---------- 1 [E] COG4302 Ethanolamine ammonia-lyase, small subunit --------------------|---------|----|------|||-|--|-----|---------- 1 [E] COG4303 Ethanolamine ammonia-lyase, large subunit -------------------------------------------------|-----|---||||--- 1 [E] COG4311 Sarcosine oxidase delta subunit -------------------------------------------------|-----|---||-|--- 1 [S] COG4312 Uncharacterized protein conserved in bacteria -------------------------------------------------|---|||----||---- 1 [C] COG4314 Predicted lipoprotein involved in nitrous oxide reduction -------------------------------------------------|-----|---||----- 1 [S] COG4315 Uncharacterized protein conserved in bacteria -------------------------------------|-----------|-----|---||----- 1 [S] COG4317 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|---|--|--- 1 [S] COG4318 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|---||||--- 1 [R] COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis -------------------------------------------------|-----|-------|-- 1 [S] COG4323 Predicted membrane protein -------------------------------------------------|-----|------|--- 1 [R] COG4324 Predicted aminopeptidase --------------|-----------|---------|------------|---------|------ 1 [S] COG4336 Uncharacterized conserved protein -------------------|-----------------------------|------------|--- 1 [S] COG4339 Uncharacterized protein conserved in bacteria -------------------|-----------------------------|-----|------|--- 1 [R] COG4341 Predicted HD phosphohydrolase ---------------------------------------------|---|---|||---------- 1 [S] COG4380 Uncharacterized protein conserved in bacteria ----------------------------------------------|--|--|--|---|------ 1 [R] COG4385 Bacteriophage P2-related tail formation protein ---------------------|---------|-|||-|----------||-----|---------- 1 [S] COG4392 Predicted membrane protein --------------------|----------------------------|----||---------- 1 [S] COG4394 Uncharacterized protein conserved in bacteria ------------------------------------------------||-----|---||||||| 1 [S] COG4395 Uncharacterized protein conserved in bacteria ----------------------------------|--|-------|---|---------------- 1 [S] COG4408 Uncharacterized protein conserved in bacteria ----------------------------------|----------|---|-----------|---- 1 [E] COG4413 Urea transporter -------------------|--------------------------|-||---------------- 1 [F J] COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA ------------------||-----------------------------|-------------|-- 1 [R] COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor --------------------|---------------------|||||--|---------|------ 1 [V] COG4452 Inner membrane protein involved in colicin E2 resistance ------------|------|----------------------------||---------||-|--- 1 [P] COG4454 Uncharacterized copper-binding protein ---------------------------------------------||--|---------|------ 1 [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion ------------------------------------------------||---------||----- 1 [C] COG4459 Periplasmic nitrate reductase system, NapE component ----------------------------------------------|--|------------|--- 1 [S] COG4460 Uncharacterized protein conserved in bacteria ---------------------------||----------------||--|---------|--|--- 1 [S] COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein ---------------------------------------------|---|--|------------- 1 [S] COG4517 Uncharacterized protein conserved in bacteria ---------------------------------------------|--||---------------- 1 [S] COG4519 Uncharacterized protein conserved in bacteria ------------------------------------------||||---|----------|-|--- 1 [P] COG4521 ABC-type taurine transport system, periplasmic component ------------------------------------------||||---|---------||-|--- 1 [P] COG4525 ABC-type taurine transport system, ATPase component ------------------------------------------|||||-||||-------|||---- 1 [P] COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin ------------------------------------------||||||||||||||---------- 1 [P] COG4535 Putative Mg2+ and Co2+ transporter CorC ----------------------------------|-------|||||-||||---|----|||||| 1 [P] COG4536 Putative Mg2+ and Co2+ transporter CorB -------------||----------------------------------|-----|---------- 1 [S] COG4539 Predicted membrane protein ---------------------------------------------||--|--|--|---------- 1 [R] COG4540 Phage P2 baseplate assembly protein gpV ----------------------------------|-|------------|---------|||---- 1 [P] COG4548 Nitric oxide reductase activation protein -------------------|-----------------------------|-----|------|--- 1 [R] COG4551 Predicted protein tyrosine phosphatase ---------------------|----|----------------|||--||-|-------||-|--- 1 [P] COG4558 ABC-type hemin transport system, periplasmic component ---------------------|----|----------------|||--||---------||-|--- 1 [P] COG4559 ABC-type hemin transport system, ATPase component ----------------------------------------------|--|-|---|---|||||-- 1 [T] COG4566 Response regulator -------------------------------------------------|--|--|---|||||-- 1 [T K] COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain ------------------------------------------|||||-||---------------- 1 [K] COG4568 Transcriptional antiterminator ------------------------------------------|||||--|---------------| 1 [R] COG4574 Serine protease inhibitor ecotin ------------------------------------------|||||--|-----|---------- 1 [T] COG4579 Isocitrate dehydrogenase kinase/phosphatase -------------------------------------------------|-----|---||||--- 1 [E] COG4583 Sarcosine oxidase gamma subunit --------------------|---------------------||||--||-|--------|----- 1 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase ---------------------------------------------|--||---------------- 1 [R] COG4590 ABC-type uncharacterized transport system, permease component ------------------------------------------|||||-||---------------- 1 [P] COG4592 ABC-type Fe2+-enterobactin transport system, periplasmic component ---|--|||-|-|----|-|-|--||----||||-||-||||-------|-----|---||||--- 1 [R] COG4603 ABC-type uncharacterized transport system, permease component --|||||||-|||---||--||||-||---||||||||-||||||||-||||---||||||||--- 1 [E] COG4608 ABC-type oligopeptide transport system, ATPase component ------------------------------------------|||-|--|-----|--|------- 1 [Q P] COG4615 ABC-type siderophore export system, fused ATPase and permease components --------------------|----------------------------|--|--|---|--|--- 1 [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain ---------------------|---------------------------|-----|---||||--- 1 [F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A ---------------------|---------------------------|-----|---|||||-- 1 [F] COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B -------------------|-----------------------------|----------|----- 1 [R] COG4637 Predicted ATPase ------------------|-------------||---------------|---||-------|--- 1 [S] COG4642 Uncharacterized protein conserved in bacteria ------------------------------------------|||-|--|-----|---------- 1 [K T] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain ------------------------------------------|||||-||--|--|----|||--- 1 [P] COG4651 Kef-type K+ transport system, predicted NAD-binding component ----------------|--------------------------------|-----|---------- 1 [C] COG4654 Cytochrome c551/c552 -------------------------------------------------|-----|---||-|--- 1 [S] COG4655 Predicted membrane protein --|--------------|--|---||---------|------||||||||||-------------- 1 [C] COG4656 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC --|--------------|--|---------------------||||||||||-------------- 1 [C] COG4657 Predicted NADH:ubiquinone oxidoreductase, subunit RnfA --|--------------|--|---|-----------------||||||||||-------------- 1 [C] COG4658 Predicted NADH:ubiquinone oxidoreductase, subunit RnfD --|--------------|--|---------------------||||||||||-------------- 1 [C] COG4659 Predicted NADH:ubiquinone oxidoreductase, subunit RnfG --|--------------|--|---------------------||||||||||-------------- 1 [C] COG4660 Predicted NADH:ubiquinone oxidoreductase, subunit RnfE ---|----|---|--------|---------------|----------||-|--------||---- 1 [R] COG4666 TRAP-type uncharacterized transport system, fused permease components ---------------------|--------||-|||||--|-||||||||||---|---------- 1 [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain ----------------------||-------------------||||--|-----|------|--- 1 [U] COG4669 Type III secretory pathway, lipoprotein EscJ -------------------------------------------||||--|-----|---------- 1 [S] COG4672 Phage-related protein ------------------||-|----|----------|-------|---|-----|---||-|--- 1 [R] COG4674 Uncharacterized ABC-type transport system, ATPase component ------------------------------------------|||||--|-----|---------- 1 [S] COG4681 Uncharacterized protein conserved in bacteria ------------------------------------------|||----|-----|---------- 1 [S] COG4685 Uncharacterized protein conserved in bacteria --|----------------------------||-------------|--|---------------- 1 [E] COG4690 Dipeptidase ---------------------------------------------|---|-----|---------- 1 [Q] COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis -------------------------------------------||||--|-----|---------- 1 [S] COG4718 Phage-related protein -------------------------------------------||||--|-----|---------- 1 [S] COG4723 Phage-related protein, tail component -------------------------------------------------|--||||---------- 1 [N U] COG4726 Tfp pilus assembly protein PilX ------------------------------|------------------|-----|---------- 1 [S] COG4728 Uncharacterized protein conserved in bacteria ---|----|----------------------------|-----------|-|-------------- 1 [S] COG4729 Uncharacterized conserved protein -------------------------------------------||||--|-----|---------- 1 [S] COG4733 Phage-related protein, tail component |-|------|---------------------------------------|---------------- 1 [S] COG4744 Uncharacterized conserved protein -------------------------------------------------|---------||||--- 1 [S] COG4764 Uncharacterized protein conserved in bacteria -------------||-||||||||||----------------|||||||||||||||||||||||| 1 [M] COG4775 Outer membrane protein/protective antigen OMA87 -------------------|----------------------||||---|---------||-|--- 1 [P] COG4778 ABC-type phosphonate transport system, ATPase component --------------------------|---------------|||||-||---------|------ 1 [P] COG4779 ABC-type enterobactin transport system, permease component ----------------|-||----------------------|||||-||--|--|-----|||-- 1 [R] COG4783 Putative Zn-dependent protease, contains TPR repeats -------------------------------------------------|---------||||--- 1 [R] COG4784 Putative Zn-dependent protease ----------------||------||----|----|||----||||||||-----|||||||||-- 1 [N] COG4786 Flagellar basal body rod protein ------------------------------------------||||||||-----|---------- 1 [N] COG4787 Flagellar basal body rod protein ----------------------||-------------------||||--|-----|------|--- 1 [U] COG4789 Type III secretory pathway, component EscV -------------------------------------------||||--|-----|------|--- 1 [U] COG4790 Type III secretory pathway, component EscR ----------------------||-------------------||||--|-----|------|--- 1 [U] COG4791 Type III secretory pathway, component EscT -------------------------------------------||||--|------------|--- 1 [U] COG4792 Type III secretory pathway, component EscU ----------------------||-------------------||||--|-----|------|--- 1 [U] COG4794 Type III secretory pathway, component EscS ----------------||||----------------------|||||-||||||||---------- 1 [U] COG4796 Type II secretory pathway, component HofQ --------------------|---------------------|||||--|---------------- 1 [S] COG4807 Uncharacterized protein conserved in bacteria --------------------------|||--------------------|---------------- 1 [Q] COG4829 Muconolactone delta-isomerase --------------------|----------------------------|---||----------- 1 [S] COG4859 Uncharacterized protein conserved in bacteria --|----------|||---|----------|-|--|------|||||--|-----|---------- 1 [S] COG4886 Leucine-rich repeat (LRR) protein ----------------------------------------------|--|-----------|---- 1 [S] COG4893 Uncharacterized protein conserved in bacteria -------------------------------------------------|-----|----|-||-- 1 [K] COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain --------------------|---------------------|||||-|||||||----|||||-- 1 [D] COG4942 Membrane-bound metallopeptidase ------------------------------------------|||-|--|--|--------|---- 1 [T] COG4943 Predicted signal transduction protein containing sensor and EAL domains ---------------------------------------------|---|-|---|---||-||-- 1 [O U] COG4960 Flp pilus assembly protein, protease CpaA ---------------------------------------------|---|-|---|---||-||-- 1 [U] COG4961 Flp pilus assembly protein TadG ||----||-|----------------|||-|--------------|---|-||--|---||-||-- 1 [U] COG4962 Flp pilus assembly protein, ATPase CpaF ---------------------------------------------|---|-|---|---||-||-- 1 [U] COG4963 Flp pilus assembly protein, ATPase CpaE ---------------------|---------------------------|-|---|---||-||-- 1 [U] COG4964 Flp pilus assembly protein, secretin CpaC --------------------------|||----------------|---|-|---|---||-||-- 1 [U] COG4965 Flp pilus assembly protein TadB -------------------------------------------------|--||||---------- 1 [N U] COG4966 Tfp pilus assembly protein PilW ------------------------------------------|||||-||--||||---------- 1 [N U] COG4967 Tfp pilus assembly protein PilV ------------------------------------------------||--||||---------- 1 [N U] COG4968 Tfp pilus assembly protein PilE ------------------||-|--------------------------||--||||---------- 1 [N U] COG4972 Tfp pilus assembly protein, ATPase PilM ------------------------------------------|||||-||||||||---------- 1 [L] COG4973 Site-specific recombinase XerC --------------------|---|-|||||---||||----|||||-||||||||---||||||| 1 [L] COG4974 Site-specific recombinase XerD ---------------------------------------------|--||---------------- 1 [P] COG4985 ABC-type phosphate transport system, auxiliary component ----------------------------------------------|--|--|--|---------- 1 [R] COG5004 P2-like prophage tail protein X ---------------------|----|---------------|||||-||-----|------||-- 1 [R] COG5006 Predicted permease, DMT superfamily ------------------------------------------||||||||||||||---------- 1 [K] COG5007 Predicted transcriptional regulator, BolA superfamily ------------------------------------------------||--||||---------- 1 [N U] COG5008 Tfp pilus assembly protein, ATPase PilU ----------------|-------||----------------|||||-||||||||---||||||| 1 [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein ---------------------------------------------|---|-|---|---||-||-- 1 [U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats ----------|-|-------------|||-----|-|-----|||-|--|-----|-----|---- 1 [C] COG5013 Nitrate reductase alpha subunit |||---|-|-------||--|---|-------|-------------|-||-|------|------- 1 [C] COG5016 Pyruvate/oxaloacetate carboxyltransferase --------------|---------------------|------------|---------------- 1 [R] COG5018 Inhibitor of the KinA pathway to sporulation, predicted exonuclease -------------------------------------------||||--|-----|---|-|---- 1 [S] COG5281 Phage-related minor tail protein ----------------------------------------------|--|-----|---------- 1 [R] COG5301 Phage-related tail fibre protein -||---||-----------------------------------------|---------------- 1 [S] COG5306 Uncharacterized conserved protein -------------||----------------------------------|---------------- 1 [G] COG5309 Exo-beta-1,3-glucanase -------------------------------------------------|---------||||--- 1 [S] COG5345 Uncharacterized protein conserved in bacteria -------------------------------------------------|---------|--|--- 1 [S] COG5351 Uncharacterized protein conserved in bacteria ---------------------------------------------|---|-----|---||-|--- 1 [S] COG5373 Predicted membrane protein ------------------------------------------------||--|------------- 1 [O] COG5380 Lipase chaperone ------------------------------------------|||||--|-----|---------- 1 [S] COG5393 Predicted membrane protein ------------------------------------------|||||--|---------------- 1 [D] COG5404 SOS-response cell division inhibitor, blocks FtsZ ring formation ----------------||-------|--------||||----|||||||||||--||||||||||| 1 [O] COG5405 ATP-dependent protease HslVU (ClpYQ), peptidase subunit -------------------------------------------||||--|-----|---------- 1 [S] COG5435 Uncharacterized conserved protein ------------------------------------------|||----|-----|---------- 1 [S] COG5445 Predicted secreted protein -------------------------------------------------|---------|-||--- 1 [S] COG5446 Predicted integral membrane protein -------------||----------------------------------|---------||-|--- 1 [S] COG5478 Predicted small integral membrane protein -------------------|-----------------------------|-----|---||-|--- 1 [R] COG5485 Predicted ester cyclase -------------------------------------------|-||--|-----|---||||--- 1 [S] COG5487 Small integral membrane protein --|---------------------------|------------------|---------------- 1 [S] COG5513 Predicted secreted protein -------------------------------------------------|----------|--|-- 1 [S] COG5528 Predicted integral membrane protein ------------------------------------------|||||--|-----|---------- 1 [R] COG5544 Predicted periplasmic lipoprotein -------------------|-----------------------------|------------|--- 1 [R] COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily ------------------------------------------||-||--|-----------|---- 1 [N] COG5567 Predicted small periplasmic lipoprotein ------------------------------------------|||-|--|-||------------- 1 [N] COG5571 Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion -----------------|------------|-----||----|||||--|---------------- 1 [M] COG5581 Predicted glycosyltransferase ------------------------------|-----||-----------|---------------- 1 [S] COG5583 Uncharacterized small protein --|--------|------||-----------------------------|-----|----|----- 1 [S] COG5607 Uncharacterized conserved protein ------|||----------------------------------------|---------------- 1 [S] COG5608 Conserved secreted protein -------------------------------------------||||--|---------------- 1 [S] COG5613 Uncharacterized conserved protein ----||------|------------------------------------|---------------- 1 [S] COG5615 Predicted integral membrane protein -------------------------------------------------|--|------|------ 1 [S] COG5619 Uncharacterized conserved protein ------------------||-----------------------------|---------------- 1 [S] COG5626 Uncharacterized conserved small protein ------------------------------------------|||||--|||-------------- 1 [R] COG5645 Predicted periplasmic lipoprotein
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