Dennis Wright

  • E-Mail
  • Phone
    • (860) 486-9451
  • Fax
    • (860) 486-6857
  • Office
    • School of Pharmacy
      Room 629
  • Mail
    • University of Connecticut
      Dept. of Pharmaceutical Sciences
      69 North Eagleville Road
      Storrs, CT 06269-3092

Professor of Medicinal Chemistry

Educational Background

  • B.S. West Liberty State College, Chemistry
  • Ph.D. Ohio University, Chemistry
  • Postdoctoral Training: Stanford University, Chemistry

Research Interests

  • Development of small-molecule therapeutics based on complex natural products
  • Therapeutic development for infectious disease, cancer and neurodegenerative disorders

Selected Publications

  • Viswanathan, K., Frey, K.M., Scocchera, E.W., Martin, B.D, Dwain, P.W., Alverson, J.B., Priestley, N.D., Anderson, A.C., Wright, D.L.  (2012) Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes,  PLoS ONE 7(2), e29434.
  • Oblak, E.Z., Wright, D.L.  (2011) Highly Substituted Oxabicyclic Derivatives from Furan: Synthesis of (±)-Platensimycin, Org. Lett. 13, 2263-5.
  • Oblak, E.Z., G-Dayanandan, N., Wright, D.L. (2011) Tandem Metathesis Reactions of Oxabicyclo[2.2.1]heptenes: Studies on the Spirocyclic Core of Cyclopamine, Org. Lett. 13, 2433-5.
  • Sunskaya, Y., Swain, P.W., Bergmeier, S.C., McMills, M.C., Priestley, N.D., Wright, D.L. (2011) Natural feedstocks for diversity-oriented synthesis:  macrolide-like scaffolds from nonactate, Arkivoc, 144-66.
  • Sundtrom, T.J., Wright, D.L. (2010) Azaviridins as new scaffolds for the development of PI-3K inhibitors, Synlett, 2875-8.
  • Paulsen, J., Liu, J., Bolstad, D., Smith, A., Priestley, N., Wright, D. and Anderson, A. (2009) In vitro biological activity and structural analysis of 2,4-diamino-5-(2’-argylpropargyl)pyrimidine inhibitors of Candida albicans, Bioorg. Med. Chem. 17, 4866-4872.