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Recent Publications (Requires Adobe Acrobat Reader)
Mundy, D., Machleidt, T., Ying, Y., Anderson, R., and Bloom G. 2002. Dual control of caeolar membran traffic by micortubules and the actin cytoskeleton. Journal of Cell Science 115:
Mateer, S.C., McDaniel, A.E., Nicolas, V., Habermacher, G.M., Sun Lin, M.J., Cromer, D.A., King, M.E., Bloom, G.S. 2002. The Mechanism for Regulation of the F-actin Binding Activity of IQGAP1 by Calcium / Calmodulin. Journal of Biological Chemistry 277: 12324-12333.
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Click to view Calcium Recovery movie
Click to view Calcium Reponse movie
Sontag, E., V. Nunbhakdi-Craig, G. Lee, R. Brandt, C. Kamibayashi, J. Kuret, C. L. White III, M.C. Mumby, and G.S. Bloom. 1999. Molecular Interactions Among Phosphatase 2A, Tau, and Microtubules: Implications for the Regulation of Tau Phosphorylation and the Development of Tauopathies. Journal of Biological Chemistry 274: 25490-25498.
Fullerton, A.T., M.-Y. Bau, P.A. Conrad. and G.S. Bloom. 1998. In Vitro Reconstitution of Microtubule Plus End-directed, GTP S-Sensitive Motility of Golgi Membranes. Molecular Biology of the Cell: 2699-2714.
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Click to view Fragments movie
Click to view Tubules movie
Click to view GTP S movie
Ratner, N., G.S. Bloom, and S.T. Brady. 1998. A Role for Cyclin-Dependent Kinase(s) in the Modulation of Fast Anerograde Axonal Transport: Effects Defined by Olomoucine and the APC Tumor Suppressor Protein. Journal of Neuroscience 18: 7717-7726.
Bashour, A.-M. and G.S. Bloom. 1998. 58K, a Microtubule-binding Golgi Protein, is a Formiminotransferase Cyclodeaminase (FTCD). Journal of Biological Chemistry 273: 19612-19617.
Bloom, G.S. and L.S.B. Goldstein. 1998. Cruising Along Microtubule Highways: How Membranes Move Through the Secretory Pathway. Journal of Cell Biology 140: 1277-1280.
Bashour, A.-M., A.T. Fullerton, M.J. Hart, and G.S. Bloom. 1997. IQGAP1, a Rac- and Cdc42-binding Protein, Is An Actin-Binding Protein That Cross-Links Microfilaments. Journal of Cell Biology: 137: 1555-1566.
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Selected Additional Papers
Lippincott-Schwartz, J., N.B. Cole, A. Marotta, P.A. Conrad and G.S. Bloom. 1995. Kinesin is the Motor for Microtubule-mediated Golgi-to-ER Membrane Traffic. Journal of Cell Biology 128: 293-306.
Elluru, R., G.S. Bloom and S.T. Brady. 1995. Fast Axonal Transport of Kinesin in the Rat Visual System: Functionality of the Kinesin Heavy Chain Isoforms. Molecular Biology of the Cell: 6: 21-40.
Sontag, E., V. Nunbhakdi-Craig, G.S. Bloom and M.C. Mumby. 1995. A Novel Pool of Protein Phosphatase 2A is Associated with Microtubules and Regulated During the Cell Cycle. Journal of Cell Biology 128: 1131-1144.
Conrad, P.A., E.J. Smart, Y.-S. Ying, R.G.W. Anderson and G.S. Bloom. 1995. Caveolin Cycles Between Plasma Membrane Caveolae and the Golgi Complex by Microtubule-dependent and Microtubule independent Steps. Journal of Cell Biology 131: 1421-1433.
Ktistakis, N., M.G. Roth and G.S. Bloom. 1991. PtK1 Cells Contain a Non-Diffusible Factor that Makes the Golgi Apparatus Resistant to Brefeldin A. Journal of Cell Biology 113: 1009-1023.
Cyr, J.L., K.K. Pfister, G.S. Bloom, C.A. Slaughter and S.T. Brady. 1991. Molecular Genetics of Kinesin Light Chains: Generation of Isoforms by Alternative Splicing. Proceedings of the National Academy of Sciences, USA 88: 10114-10118.
Vallee, R.B. and G.S. Bloom. 1991. Mechanisms of Fast and Slow Axonal Transport. Annual Review of Neuroscience 14: 59-92.
Brady, S.T., K.K. Pfister and G.S. Bloom. 1990. A Monoclonal Antibody to the Heavy Chain of Kinesin Inhibits Anterograde and Retrograde Axonal Transport in Isolated Squid Axoplasm. Proceedings of the National Academy of Sciences, USA 87: 1061-1065.
Pfister, K.K., M.C. Wagner, D.L. Stenoien, S.T. Brady and G.S. Bloom. 1989. Monoclonal Antibodies to Kinesin Heavy and Light Chains Stain Vesicle-like Structures, but not Microtubules in Cultured Cells. Journal of Cell Biology 108: 1453-1463.
Hirokawa, N., K.K. Pfister, H. Yorifuji, M.C. Wagner, S.T. Brady and G.S. Bloom. 1989. Submolecular Domains of Bovine Brain Kinesin Identified by Electron Microscopy and Monoclonal Antibody Decoration. Cell 56: 867-878.
Bloom, G.S., M.C. Wagner, K.K. Pfister and S.T. Brady. 1988. Native Structure and Physical Properties of Bovine Brain Kinesin, and Identification of the ATP-Binding Subunit Polypeptide. Biochemistry 27: 3409-3416.
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