Spring 2012

Monday, Wednesday, Friday 11-11:50am in 305 MSEB

Instructor

Dr. Ken Gentry
klgentry@illinois.edu
3105 DCL
217-333-4218
Student hours: Tuesday 12-2pm, Friday 1-3pm, or make an appointment

Description

Introduction to engineering aspects of the detection, acquisition, processing, and display of signals from living systems; biomedical sensors for measurements of biopotentials, ions and gases in aqueous solution, force, displacement, blood pressure, blood flow, heart sounds, respiration, and temperature; therapeutic and prosthetic devices; medical imaging instrumentation. Same as ECE 414. Prerequisite: BIOE 205, ECE 205 or ECE 210.

Course Objectives

  • Understand the limitations of instrumentation in terms of accuracy, resolution, precision, and reliability (l,m).
  • Analyze and design operational amplifier and instrumentation amplifier circuits to amplify biosignals (a,b,c,d).
  • Analyze and design filter circuits to filter unwanted signals from biosignals (a,b,c,d).
  • Understand the origin of cardiac and muscle biosignals and how they are acquired using ECG and electromyogram electrodes (a,c,d,e,k,m).
  • Understand electrode circuit models and how they effect signal acquisition (a,c,e,m).
  • Understand they physical modes of operation of various biosensors (amperometric, enzymatic, optical, resistive, capacitive) (a,k).
  • Describe and compare methods and instrumentation needed to measure pressure and flow in the body (a,e).
  • Determine and characterize the factors that limit medical imaging methods in biological tissue (b,m).
  • Describe the requirements and limitations of bioinstrumentation in the clinical environment (f,h,i,j).
  • Function and interact cooperatively and efficiently as a team member in completing a project (d,f,g).
  • Present work in both written and oral reports (f,g).

Required Textbook

"Medical Instrumentation: Application and Design, Fourth Edition," John Webster, Editor, published by Wiley 2009. This is the latest edition of the book with the blue and brown cover. Changes from the Third Edition are minimal, but end-of-chapter problems have different numbers. Students who use the Third Edition are advised to check the Fourth Edition before starting homework assignments.

Grading

The following grading scale will apply (>97% A+, >93-97% A, >90-93% A-, >87-90% B+, >83-87% B, >80-83% B-, >77-80% C+, >73-77% C, >70-73% C-, >67-70% D+, >63-67% D, >60-63% D-, 0-60% F). Grades will be maintained on Illinois Compass 2g.

Homework

There will be six homework assignments with each worth 10 points. Students are expected to work on the homework alone and to follow the homework guidelines found on the Homework page of this website.

Homework will be accepted up to three days late for 1/2 credit.

Projects

A group project will be worth 40 total points. The project involves researching a medical device and producing a written report and a poster.

Exams

There will be three exams. Each will cover approximately one-third of the course and will be worth 50 points.

Schedule (subject to change)

Week Monday Wednesday Friday
1/18-20 Introduction and Basic Concepts of Medical Instrumentation (1.2-7) Biostatistics (1.8)
1/23-27 Static and Dynamic Characteristics (1.9-10) Operational Amplifiers 1 (3.1-3,14) Operational Amplifiers 2 (3.4, 11)
1/30-2/3 Operational Amplifiers 3 (3.10) Origin of Biopotentials (4.1)
Homework 1 due
Electromyogram and Electrocardiogram (4.2-3,5-6)
2/6-10 Biopotential Electrodes (5.1-3) Electrode Circuit Models (5.4-6) Biopotential Amplifiers (6.1,3-5)
2/13-17 Electrocardiography (6.2-3)
Homework 2 due
Exam review Exam 1
2/20-24 Resistive Sensors (2.1-2) Bridge Circuits (2.3) Temperature Sensors (2.7-9)
2/27-3/2 Optical Sources and Sensors (2.12-16) Blood Pressure Measurement (7.1,3-4) Blood Pressure Measurement System Response (7.4-8,13)
Homework 3 due
3/5-9 Measurement of Blood Flow (8.1-2,5) Plethysmography (8.6-7) EOH - No class
3/12-16 Measurement of Respiratory Flow and Pressure (9.1-3)
3/19-23 Spring Break
3/26-30 Spirometry (9.4) Measurement of Gas Concentration (9.7)
Homework 4 due
Exam review
4/2-6 Exam 2 Spectrophotometry (11.1) Photoplethysmography and Pulse Oximetry (8.8;10.3,6)
4/9-13 Electrochemical Sensors (10.1-2) Hematology (11.5)
Homework 5 due
Introduction to Medical Imaging (12.1-4)
4/16-20 X-ray Imaging (12.5-7) Nuclear Imaging (12.9-11) MR Imaging (12.8)
4/23-27 Ultrasound Imaging (12.12) Other Electrical Stimulators (13.1-2)
Homework 6 due
Exam review
4/30-5/2 Exam 3 Poster session info
5/11 Project poster session
1:30-4:30pm in 1265 DCL
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